Downregulation of PRRX1 Confers Cancer Stem Cell-Like Properties and Predicts Poor Prognosis in Hepatocellular Carcinoma

Annals of Surgical Oncology

Volumn 22, Issue , 2015, Pages 1402-1409

  Hirata, Hidenari ^a   Sugimachi, Keishi ^a   Takahashi, Yusuke ^a,b   Ueda, Masami ^a   Sakimura, Shotaro ^a   Uchi, Ryutaro ^a   Kurashige, Junji ^a   Takano, Yuki ^a   Nanbara, Sho ^a   Komatsu, Hisateru ^a   Saito, Tomoko ^a   Shinden, Yoshiaki ^a   Iguchi, Tomohiro ^a   Eguchi, Hidetoshi ^a   Atsumi, Kazushige ^a   Sakamoto, Katsumi ^a   Doi, Toshiro ^a   Hirakawa, Masakazu ^a   Honda, Hiroshi ^c   Mimori, Koshi ^a  

^a KYUSHU UNIVERSITY BEPPU HOSPITAL   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; EPITHELIAL CELL ADHESION MOLECULE; FLUOROURACIL; MICROSOMAL AMINOPEPTIDASE; PAIRED RELATED HOMEOBOX 1; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; HOMEODOMAIN PROTEIN; MESSENGER RNA; PRRX1 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER INHIBITION; CANCER PROGNOSIS; CANCER RESISTANCE; CANCER STEM CELL; CELL ADHESION; CELL GROWTH; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; FEMALE; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOSENSITIVITY; UPREGULATION; APOPTOSIS; CANCER STAGING; CELL PROLIFERATION; DRUG EFFECTS; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BIOMARKERS, TUMOR; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; MALE; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 84952870034     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-4242-0     Document Type: Article

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