Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 6, 2015, Pages 1703-1706.e5

  Romao, Susana ^a,b   Puente, Emilio Tejera ^b   Nytko, Katarzyna J ^b   Siler, Ulrich ^b   Münz, Christian ^a   Reichenbach, Janine ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

3 MA; HISTONE; HISTONE H4; HYDROLASE; LEUKOCYTE ELASTASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; WORTMANNIN; 3-METHYLADENINE; ADENINE; ANDROSTANE DERIVATIVE; BENZYLAMINE DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; QUINAZOLINE DERIVATIVE; SPAUTIN-1;

AUTOPHAGOSOME; BACTERIAL INFECTION; CANDIDA ALBICANS; CELL NUCLEUS MEMBRANE; CELL STIMULATION; CHRONIC GRANULOMATOUS DISEASE; CONFOCAL MICROSCOPY; EXTRACELLULAR TRAP; HUMAN; LETTER; MACROAUTOPHAGY; MYCOSIS; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL NUCLEUS; DRUG EFFECTS; IMMUNOLOGY; METABOLISM;

ADENINE; ANDROSTADIENES; BENZYLAMINES; CANDIDA ALBICANS; CELL NUCLEUS; EXTRACELLULAR TRAPS; GRANULOMATOUS DISEASE, CHRONIC; HISTONES; HUMANS; HYDROLASES; NEUTROPHILS; PHOSPHATIDYLINOSITOL 3-KINASES; QUINAZOLINES; REACTIVE OXYGEN SPECIES; TETRADECANOYLPHORBOL ACETATE;

EID: 84952637417     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.09.007     Document Type: Article

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