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EIF4G1 R1205H and VPS35 D620N mutations are rare in Parkinson's disease from South Africa
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Translation initiator EIF4G1 mutations in familial Parkinson disease
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Chartier-Harlin M.C., Dachsel J.C., Vilariño-Güell C., Lincoln S.J., Leprêtre F., Hulihan M.M., Kachergus J., Milnerwood A.J., Tapia L., Song M.S., Le Rhun E., Mutez E., Larvor L., Duflot A., Vanbesien-Mailliot C., Kreisler A., Ross O.A., Nishioka K., Soto-Ortolaza A.I., Cobb S.A., Melrose H.L., Behrouz B., Keeling B.H., Bacon J.A., Hentati E., Williams L., Yanagiya A., Sonenberg N., Lockhart P.J., Zubair A.C., Uitti R.J., Aasly J.O., Krygowska-Wajs A., Opala G., Wszolek Z.K., Frigerio R., Maraganore D.M., Gosal D., Lynch T., Hutchinson M., Bentivoglio A.R., Valente E.M., Nichols W.C., Pankratz N., Foroud T., Gibson R.A., Hentati F., Dickson D.W., Destée A., Farrer M.J. Translation initiator EIF4G1 mutations in familial Parkinson disease. Am. J. Hum. Genet. 2011, 89:398-406.
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Nishioka, K.18
Soto-Ortolaza, A.I.19
Cobb, S.A.20
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Williams, L.26
Yanagiya, A.27
Sonenberg, N.28
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Zubair, A.C.30
Uitti, R.J.31
Aasly, J.O.32
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Opala, G.34
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Maraganore, D.M.37
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Bentivoglio, A.R.41
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3
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VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from Southwest China
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Chen Y., Chen K., Song W., Chen X., Cao B., Huang R., Zhao B., Guo X., Burgunder J., Li J., Shang H.F. VPS35 Asp620Asn and EIF4G1 Arg1205His mutations are rare in Parkinson disease from Southwest China. Neurobiol. Aging 2013, 34:1709.e7-1709.e8.
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Chen, Y.1
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Chen, X.4
Cao, B.5
Huang, R.6
Zhao, B.7
Guo, X.8
Burgunder, J.9
Li, J.10
Shang, H.F.11
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4
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Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein
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Dhungel N., Eleuteri S., Li L.B., Kramer N.J., Chartron J.W., Spencer B., Kosberg K., Fields J.A., Stafa K., Adame A., Lashuel H., Frydman J., Shen K., Masliah E., Gitler AD. Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein. Neuron 2015, 85:657.
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Lashuel, H.11
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Masliah, E.14
Gitler, A.D.15
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Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia
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Fujioka S., Sundal C., Strongosky A.J., Castanedes M.C., Rademakers R., Ross O.A., Vilariño-Güell C., Farrer M.J., Wszolek Z.K., Dickson D.W. Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia. Acta Neuropathol. 2013, 125:425-438.
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Fujioka, S.1
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Ross, O.A.6
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Farrer, M.J.8
Wszolek, Z.K.9
Dickson, D.W.10
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EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts
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Huttenlocher J., Krüger R., Capetian P., Lohmann K., Brockmann K., Csoti I., Klein C., Berg D., Gasser T., Bonin M., Riess O., Bauer P. EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts. J. Med. Genet. 2014, November. doi:10.1136/jmedgenet-2014-102570.
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EIF4G1 in familial Parkinson's disease: pathogenic mutations or rare benign variants?
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Lesage S., Condroyer C., Klebe S., Lohmann E., Durif F., Damier P., Tison F., Anheim M., Honoré A., Viallet F., Bonnet A.M., Ouvrard-Hernandez A.M., Vidailhet M., Durr A., Brice A. EIF4G1 in familial Parkinson's disease: pathogenic mutations or rare benign variants?. Neurobiol. Aging 2012, 33:2233.e1-2233.e5. French Parkinson's Disease Genetics Study Group.
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Largescale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
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International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI); 23andMe; GenePD; NeuroGenetics Research Consortium (NGRC); Hussman Institute of Human Genomics (HIHG); Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC); Greek Parkinson's Disease Consortium; Alzheimer Genetic Analysis Group, Ikram M.A., Ioannidis J.P., Hadjigeorgiou G.M., Bis J.C., Martinez M., Perlmutter J.S., Goate A., Marder K., Fiske B., Sutherland M., Xiromerisiou G., Myers R.H., Clark L.N., Stefansson K., Hardy J.A., Heutink P., Chen H., Wood N.W., Houlden H., Payami H., Brice A., Scott W.K., Gasser T., Bertram L., Eriksson N., Foroud T., Singleton A.B.
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Nalls, M.A., Pankratz, N., Lill, C.M., Do, C.B., Hernandez, D.G., Saad, M., DeStefano, A.L., Kara E., Bras J., Sharma M., Schulte C., Keller M.F., Arepalli S., Letson C., Edsall C., Stefansson H., Liu X., Pliner H., Lee J.H., Cheng R.; International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI); 23andMe; GenePD; NeuroGenetics Research Consortium (NGRC); Hussman Institute of Human Genomics (HIHG); Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC); Greek Parkinson's Disease Consortium; Alzheimer Genetic Analysis Group, Ikram M.A., Ioannidis J.P., Hadjigeorgiou G.M., Bis J.C., Martinez M., Perlmutter J.S., Goate A., Marder K., Fiske B., Sutherland M., Xiromerisiou G., Myers R.H., Clark L.N., Stefansson K., Hardy J.A., Heutink P., Chen H., Wood N.W., Houlden H., Payami H., Brice A., Scott W.K., Gasser T., Bertram L., Eriksson N., Foroud T., Singleton A.B., 2014. Largescale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat. Genet. 46, 989-993.
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EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population
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Nishioka K., Funayama M., Vilariño-Güell C., Ogaki K., Li Y., Sasaki R., Kokubo Y., Kuzuhara S., Kachergus J.M., Cobb S.A., Takahashi H., Mizuno Y., Farrer M.J., Ross O.A., Hattori N. EIF4G1 gene mutations are not a common cause of Parkinson's disease in the Japanese population. Parkinsonism Relat. Disord. 2014, 20:659-661.
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Farrer, M.J.13
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Mutations in EIF4G1 are not a common cause of Parkinson's disease
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Study of the genetic variability in a Parkinson's disease gene: EIF4G1
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