Delayed hemoglobin switching and perinatal neocytolysis in mice with gain-of-function erythropoietin receptor

Journal of Molecular Medicine

Volumn 94, Issue 5, 2016, Pages 597-608

  Divoky, Vladimir ^a   Song, Jihyun ^b   Horvathova, Monika ^a   Kralova, Barbora ^a   Votavova, Hana ^c   Prchal, Josef T ^b   Yoon, Donghoon ^b,d  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Augmented Stat5 signaling; Fetal polycythemia; Human EPOR mutation; Neocytolysis; Prolonged primitive erythropoiesis

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; HEMOGLOBIN; PHOSPHATIDYLSERINE; STAT5 PROTEIN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; FETUS LIVER; GAIN OF FUNCTION MUTATION; GENOTYPE; HEMATOCRIT; LIVER CELL; MOUSE; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; POLYCYTHEMIA; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; TRANSGENIC MOUSE;

ANEMIA; ANIMALS; ERYTHROCYTES; ERYTHROID PRECURSOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN; GAIN OF FUNCTION MUTATION; GENE EXPRESSION REGULATION; GENOTYPE; HEMATOCRIT; HEMOGLOBINS; HUMANS; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; POLYCYTHEMIA; RECEPTORS, ERYTHROPOIETIN; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR;

EID: 84952038094     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-015-1375-y     Document Type: Article

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