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Volumn 53, Issue 1, 2016, Pages 37-43

Ki-67 as a Prognostic Factor in Feline Mammary Carcinoma: What Is the Optimal Cutoff Value?

Author keywords

cutoff value; feline mammary carcinoma; Ki 67 proliferation index; prognostic factor

Indexed keywords

KI 67 ANTIGEN; TUMOR MARKER;

EID: 84952002585     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1177/0300985815588606     Document Type: Article
Times cited : (27)

References (45)
  • 1
    • 84873828310 scopus 로고    scopus 로고
    • Expression of ER/PR/HER2, basal markers and adhesion molecules in primary breast cancer and in lymph nodes metastases: a comparative immunohistochemical analysis
    • A.AdamczykJ.NiemiecA.Ambicka. Expression of ER/PR/HER2, basal markers and adhesion molecules in primary breast cancer and in lymph nodes metastases: a comparative immunohistochemical analysis. Pol J Pathol. 2012;63:226–234.
    • (2012) Pol J Pathol , vol.63 , pp. 226-234
    • Adamczyk, A.1    Niemiec, J.2    Ambicka, A.3
  • 2
    • 84875252409 scopus 로고    scopus 로고
    • Molecular phenotype in mammary tumours of queens: correlation between primary tumour and lymph node metastasis
    • B.BrunettiP.AsproniG.Beha. Molecular phenotype in mammary tumours of queens: correlation between primary tumour and lymph node metastasis. J Comp Pathol. 2013;148:206–213.
    • (2013) J Comp Pathol , vol.148 , pp. 206-213
    • Brunetti, B.1    Asproni, P.2    Beha, G.3
  • 3
    • 77951042246 scopus 로고    scopus 로고
    • Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions
    • G.P.BurraiS.I.MohammedM.A.Miller. Spontaneous feline mammary intraepithelial lesions as a model for human estrogen receptor- and progesterone receptor-negative breast lesions. BMC Cancer. 2010;10:156.
    • (2010) BMC Cancer , vol.10 , pp. 156
    • Burrai, G.P.1    Mohammed, S.I.2    Miller, M.A.3
  • 4
    • 0032199152 scopus 로고    scopus 로고
    • Ki-67 index as indicator of the post-surgical prognosis in feline mammary carcinomas
    • M.CastagnaroR.De MariaE.Bozzetta. Ki-67 index as indicator of the post-surgical prognosis in feline mammary carcinomas. Res Vet Sci. 1998;65(3):223–226.
    • (1998) Res Vet Sci , vol.65 , Issue.3 , pp. 223-226
    • Castagnaro, M.1    De Maria, R.2    Bozzetta, E.3
  • 5
    • 66849140730 scopus 로고    scopus 로고
    • Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer
    • M.C.U.CheangS.K.ChiaD.Voduc. Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst. 2009;101:736–750.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 736-750
    • Cheang, M.C.U.1    Chia, S.K.2    Voduc, D.3
  • 6
    • 79952018585 scopus 로고    scopus 로고
    • Prognostic significance of Ki-67 labeling índex after short-term presurgical tamoxifen in women with ER-positive breast cancer
    • A.DeCensiA.Guerrieri-GonzagaS.Gandini. Prognostic significance of Ki-67 labeling índex after short-term presurgical tamoxifen in women with ER-positive breast cancer. Ann Oncol. 2011;22:582–587.
    • (2011) Ann Oncol , vol.22 , pp. 582-587
    • DeCensi, A.1    Guerrieri-Gonzaga, A.2    Gandini, S.3
  • 7
    • 84887042578 scopus 로고    scopus 로고
    • Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial
    • C.DenkertS.LoiblB.M.Müller. Ki67 levels as predictive and prognostic parameters in pretherapeutic breast cancer core biopsies: a translational investigation in the neoadjuvant GeparTrio trial. Ann Oncol. 2013;24(11):2786–2793.
    • (2013) Ann Oncol , vol.24 , Issue.11 , pp. 2786-2793
    • Denkert, C.1    Loibl, S.2    Müller, B.M.3
  • 8
    • 84871762532 scopus 로고    scopus 로고
    • Effect of ASCO/CAP guidelines for determining ER status on Molecular subtype
    • B.DeyarminJ.L.KaneA.L.Valente. Effect of ASCO/CAP guidelines for determining ER status on Molecular subtype. Ann Surg Oncol. 2013;20(1):87–93.
    • (2013) Ann Surg Oncol , vol.20 , Issue.1 , pp. 87-93
    • Deyarmin, B.1    Kane, J.L.2    Valente, A.L.3
  • 9
    • 81555208345 scopus 로고    scopus 로고
    • Assessment of Ki67 in breast cancer: recommendations from the international Ki67 in Breast Cancer Working Group
    • M.DowsettT.O.NielsenR.A’Hern. Assessment of Ki67 in breast cancer: recommendations from the international Ki67 in Breast Cancer Working Group. J Natl Cancer Inst. 2011;103:1656–1664.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1656-1664
    • Dowsett, M.1    Nielsen, T.O.2    A’Hern, R.3
  • 10
    • 0000055417 scopus 로고    scopus 로고
    • Assessment of histological grade
    • Rosen P.P., (ed), Philadelphia, PA: Lippincott-Raven,,. In:,, ed
    • C.W.ElstonI.O.Ellis. Assessment of histological grade. In: P.P.Rosen, ed. Rosen’s Breast Pathology. Philadelphia, PA: Lippincott-Raven; 1998:365–382.
    • (1998) Rosen’s Breast Pathology , pp. 365-382
    • Elston, C.W.1    Ellis, I.O.2
  • 11
    • 81055148214 scopus 로고    scopus 로고
    • Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment
    • P.A.FaschingK.HeusingerL.Haeberle. Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment. BMC Cancer. 2011;11:486.
    • (2011) BMC Cancer , vol.11 , pp. 486
    • Fasching, P.A.1    Heusinger, K.2    Haeberle, L.3
  • 12
    • 84883325272 scopus 로고    scopus 로고
    • Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
    • A.GoldhirschE.P.WinerA.S.Coates. Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013. Ann Oncol. 2013;24:2206–2223.
    • (2013) Ann Oncol , vol.24 , pp. 2206-2223
    • Goldhirsch, A.1    Winer, E.P.2    Coates, A.S.3
  • 13
    • 77954331064 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version)
    • M.E.HammondD.F.HayesM.Dowsett. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version). Arch Pathol Lab Med. 2010;134(7):48–72.
    • (2010) Arch Pathol Lab Med , vol.134 , Issue.7 , pp. 48-72
    • Hammond, M.E.1    Hayes, D.F.2    Dowsett, M.3
  • 14
    • 36849069347 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer
    • L.HarrisH.FritscheR.Mennel. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol. 2007;25(33):5287–5312.
    • (2007) J Clin Oncol , vol.25 , Issue.33 , pp. 5287-5312
    • Harris, L.1    Fritsche, H.2    Mennel, R.3
  • 15
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen Receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • J.M.HarveyG.M.ClarkC.K.Osborne. Estrogen Receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol. 1999;17(5):1474–1481.
    • (1999) J Clin Oncol , vol.17 , Issue.5 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3
  • 16
    • 84874207349 scopus 로고    scopus 로고
    • ER, PR, HER2, Ki-67 and Ck5 in early and late relapsing breast cancer: reduced Ck5 expression in metastases
    • K.JoensuuM.LeideniusM.Kero. ER, PR, HER2, Ki-67 and Ck5 in early and late relapsing breast cancer: reduced Ck5 expression in metastases. Breast Cancer (Auckl). 2013;7:23–34.
    • (2013) Breast Cancer (Auckl) , vol.7 , pp. 23-34
    • Joensuu, K.1    Leidenius, M.2    Kero, M.3
  • 17
    • 84860390436 scopus 로고    scopus 로고
    • Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis
    • B.KeamS.A.ImK.H.Lee. Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis. Breast Cancer Res. 2011;13:R22.
    • (2011) Breast Cancer Res , vol.13 , pp. R22
    • Keam, B.1    Im, S.A.2    Lee, K.H.3
  • 18
    • 84865171628 scopus 로고    scopus 로고
    • Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review
    • E.LuporsiF.AndreF.Spyratos. Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review. Breast Cancer Res Treat. 2012;132:895–915.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 895-915
    • Luporsi, E.1    Andre, F.2    Spyratos, F.3
  • 19
    • 0021763820 scopus 로고
    • Prognostic factors for feline mammary tumors
    • E.G.MacEwenA.A.HayesH.J.Harvey. Prognostic factors for feline mammary tumors. J Am Vet Med Assoc. 1984;185(2):201–204.
    • (1984) J Am Vet Med Assoc , vol.185 , Issue.2 , pp. 201-204
    • MacEwen, E.G.1    Hayes, A.A.2    Harvey, H.J.3
  • 20
    • 0242455889 scopus 로고    scopus 로고
    • Role of HER2 gene overexpression in breast carcinoma
    • S.MénardE.TagliabueM.Campiglio. Role of HER2 gene overexpression in breast carcinoma. J Cell Physiol. 2000;182(2):150–162.
    • (2000) J Cell Physiol , vol.182 , Issue.2 , pp. 150-162
    • Ménard, S.1    Tagliabue, E.2    Campiglio, M.3
  • 21
    • 13244251101 scopus 로고    scopus 로고
    • Overexpression of HER-2 in feline invasive mammary carcinomas: na immunohistochemical survey and evaluation of its prognostic potential
    • F.MillantaM.CalandrellaS.Citi. Overexpression of HER-2 in feline invasive mammary carcinomas: na immunohistochemical survey and evaluation of its prognostic potential. Vet Pathol. 2005;42:30–34.
    • (2005) Vet Pathol , vol.42 , pp. 30-34
    • Millanta, F.1    Calandrella, M.2    Citi, S.3
  • 22
    • 33745698623 scopus 로고    scopus 로고
    • Steroid hormone receptors in normal, dysplastic and neoplastic feline mammary tissues and their prognostic significance
    • F.MillantaM.CalandrellaI.Vannozzi. Steroid hormone receptors in normal, dysplastic and neoplastic feline mammary tissues and their prognostic significance. Veterinary Record. 2006;158:821–824.
    • (2006) Veterinary Record , vol.158 , pp. 821-824
    • Millanta, F.1    Calandrella, M.2    Vannozzi, I.3
  • 23
    • 0036052806 scopus 로고    scopus 로고
    • MIB-1 labeling index in feline dysplastic and neoplastic mammary lesions and its relationship with postsurgical prognosis
    • F.MillantaG.LazzeriM.Mazzei. MIB-1 labeling index in feline dysplastic and neoplastic mammary lesions and its relationship with postsurgical prognosis. Vet Pathol. 2002;39:120–126.
    • (2002) Vet Pathol , vol.39 , pp. 120-126
    • Millanta, F.1    Lazzeri, G.2    Mazzei, M.3
  • 25
    • 10344263365 scopus 로고    scopus 로고
    • Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study
    • S.K.MohsinH.WeissT.Havighurst. Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study. Mod Pathol. 2004;17:1545–1554.
    • (2004) Mod Pathol , vol.17 , pp. 1545-1554
    • Mohsin, S.K.1    Weiss, H.2    Havighurst, T.3
  • 26
    • 84888246639 scopus 로고    scopus 로고
    • Randomized trial of preoperative docetaxel with or without capecitabine after 4 cycles of 5–fluorouracil-epirubicin-cyclophosphamide (FEC) in early-stage breast cancer: exploratory analyses identify Ki67 as a predictive biomarker for response to neoadjuvant chemotherapy
    • S.OhnoL.W.C.ChowN.Sato. Randomized trial of preoperative docetaxel with or without capecitabine after 4 cycles of 5–fluorouracil-epirubicin-cyclophosphamide (FEC) in early-stage breast cancer: exploratory analyses identify Ki67 as a predictive biomarker for response to neoadjuvant chemotherapy. Breast Cancer Res Treat. 2013;142:69–80.
    • (2013) Breast Cancer Res Treat , vol.142 , pp. 69-80
    • Ohno, S.1    Chow, L.W.C.2    Sato, N.3
  • 27
    • 84875919958 scopus 로고    scopus 로고
    • Prognostic impact of Ki-67 labeling indices with 3 different cut-off values, histological grade, and nuclear grade in hormone-receptor-positive, HER2-negative, node-negative invasive breast cancers
    • M.OnoH.TsudaM.Yunokawa. Prognostic impact of Ki-67 labeling indices with 3 different cut-off values, histological grade, and nuclear grade in hormone-receptor-positive, HER2-negative, node-negative invasive breast cancers. Breast Cancer. 2013;22:141–152.
    • (2013) Breast Cancer , vol.22 , pp. 141-152
    • Ono, M.1    Tsuda, H.2    Yunokawa, M.3
  • 28
    • 84856358910 scopus 로고    scopus 로고
    • Characteristics and outcomes according to molecular subtypes of breast cancer as classified by panel of four biomarkers using immunohistochemistry
    • S.ParkJ.S.KooM.S.Kim. Characteristics and outcomes according to molecular subtypes of breast cancer as classified by panel of four biomarkers using immunohistochemistry. Breast. 2012;21:50–57.
    • (2012) Breast , vol.21 , pp. 50-57
    • Park, S.1    Koo, J.S.2    Kim, M.S.3
  • 29
    • 84878344513 scopus 로고    scopus 로고
    • Ki67 and proliferation in breast cancer
    • N.PathmanathanR.L.Balleine. Ki67 and proliferation in breast cancer. J Clin Pathol. 2013;66:512–516.
    • (2013) J Clin Pathol , vol.66 , pp. 512-516
    • Pathmanathan, N.1    Balleine, R.L.2
  • 30
    • 4344672151 scopus 로고    scopus 로고
    • Cell proliferation in feline normal, hyperplastic and neoplastic mammary tissue: an immunohistochemical study
    • P.D.PereiraJ.CarvalheiraF.Gärtner. Cell proliferation in feline normal, hyperplastic and neoplastic mammary tissue: an immunohistochemical study. Vet J. 2004;168:180–185.
    • (2004) Vet J , vol.168 , pp. 180-185
    • Pereira, P.D.1    Carvalheira, J.2    Gärtner, F.3
  • 31
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • C.M.PerouT.SurlieM.B.Eisen. Molecular portraits of human breast tumours. Nature. 2000;406:747–752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Surlie, T.2    Eisen, M.B.3
  • 32
    • 0036700127 scopus 로고    scopus 로고
    • Multiparametric survival analysis of histological stage and proliferative activity in feline mammary carcinomas
    • R.PreziosiG.SarliC.Benazzi. Multiparametric survival analysis of histological stage and proliferative activity in feline mammary carcinomas. Res Vet Sci. 2002;73:53–60.
    • (2002) Res Vet Sci , vol.73 , pp. 53-60
    • Preziosi, R.1    Sarli, G.2    Benazzi, C.3
  • 33
    • 79551505266 scopus 로고    scopus 로고
    • An immunohistochemical study of HER-2 expression in feline mammary tumours
    • R.RasottoD.CaliariM.Castagnaro. An immunohistochemical study of HER-2 expression in feline mammary tumours. J Comp Path. 2011;144(2–3):170–179.
    • (2011) J Comp Path , vol.144 , Issue.2-3 , pp. 170-179
    • Rasotto, R.1    Caliari, D.2    Castagnaro, M.3
  • 34
    • 84896549618 scopus 로고    scopus 로고
    • Benefit from anthracyclines in relation to biological profiles in early breast cancer
    • A.RoccaS.BravacciniE.Scarpi. Benefit from anthracyclines in relation to biological profiles in early breast cancer. Breast Cancer Res Treat. 2014;144(2):307–318.
    • (2014) Breast Cancer Res Treat , vol.144 , Issue.2 , pp. 307-318
    • Rocca, A.1    Bravaccini, S.2    Scarpi, E.3
  • 35
    • 84891317175 scopus 로고    scopus 로고
    • ERBB2 in cat mammary neoplasias disclosed a positive correlation between RNA and protein low expression levels: a model for erbB-2 negative human breast cancer
    • S.SantosC.BaptistaR.M.V.Abreu. ERBB2 in cat mammary neoplasias disclosed a positive correlation between RNA and protein low expression levels: a model for erbB-2 negative human breast cancer. Plos One. 2013;8(12):e83673.
    • (2013) Plos One , vol.8 , Issue.12 , pp. e83673
    • Santos, S.1    Baptista, C.2    Abreu, R.M.V.3
  • 36
    • 77951887041 scopus 로고    scopus 로고
    • Molecular-based tumour subtypes of canine mammary carcinomas assessed by immunohistochemistry
    • F.SassiC.BenazziG.Castellani. Molecular-based tumour subtypes of canine mammary carcinomas assessed by immunohistochemistry. BMC Vet Res. 2010;6:5.
    • (2010) BMC Vet Res , vol.6 , pp. 5
    • Sassi, F.1    Benazzi, C.2    Castellani, G.3
  • 37
    • 78650555787 scopus 로고    scopus 로고
    • Grade is an independent prognostic factor for feline mammary carcinomas: a clinicopathological and survival analysis
    • F.SeixasC.PalmeiraM.A.Pires. Grade is an independent prognostic factor for feline mammary carcinomas: a clinicopathological and survival analysis. Vet J. 2011;187(1):65–71.
    • (2011) Vet J , vol.187 , Issue.1 , pp. 65-71
    • Seixas, F.1    Palmeira, C.2    Pires, M.A.3
  • 38
    • 84880270936 scopus 로고    scopus 로고
    • Feline HER2 protein expression levels and gene status in feline mammary carcinoma: optimization of immunohistochemistry (IHC) and in situ hybridization (ISH) techniques
    • M.SoaresJ.CorreiaP.Rodrigues. Feline HER2 protein expression levels and gene status in feline mammary carcinoma: optimization of immunohistochemistry (IHC) and in situ hybridization (ISH) techniques. Microsc Microanal. 2013;19:1–7.
    • (2013) Microsc Microanal , vol.19 , pp. 1-7
    • Soares, M.1    Correia, J.2    Rodrigues, P.3
  • 39
    • 84901863871 scopus 로고    scopus 로고
    • Tumors of the mammary gland
    • Withrow S.J., Vail D.M., Page R.L., (eds), 5th, Missouri, MO: Saunders,,. In:,, eds., ed
    • K.U.SorenmoD.R.WorleyM.H.Goldschmidt. Tumors of the mammary gland. In: S.J.WithrowD.M.VailR.L.Page, eds. Small Animal Clinical Oncology. 5th ed. Missouri, MO: Saunders; 2013:538–556.
    • (2013) Small Animal Clinical Oncology , pp. 538-556
    • Sorenmo, K.U.1    Worley, D.R.2    Goldschmidt, M.H.3
  • 40
    • 84912079307 scopus 로고    scopus 로고
    • Prognostic value of Ki-67 expression in HR-negative breast cancer before and after neoadjuvant chemotherapy
    • Q.X.TanQ.H.QinW.P.Yang. Prognostic value of Ki-67 expression in HR-negative breast cancer before and after neoadjuvant chemotherapy. Int J Clin Exp Pathol. 2014;7:6862–6870.
    • (2014) Int J Clin Exp Pathol , vol.7 , pp. 6862-6870
    • Tan, Q.X.1    Qin, Q.H.2    Yang, W.P.3
  • 41
    • 79251598806 scopus 로고    scopus 로고
    • Prognostic significance of Ki67 index after neoadjuvant chemotherapy in breast cancer
    • T.TaneiA.ShimomuraK.Shimazu. Prognostic significance of Ki67 index after neoadjuvant chemotherapy in breast cancer. EJSO. 2011;37:155–161.
    • (2011) EJSO , vol.37 , pp. 155-161
    • Tanei, T.1    Shimomura, A.2    Shimazu, K.3
  • 42
    • 73349088461 scopus 로고    scopus 로고
    • Animal tumour registry of two provinces in northern Italy: incidence of spontaneous tumours in dogs and cats
    • M.VascellariE.BaioniG.Ru. Animal tumour registry of two provinces in northern Italy: incidence of spontaneous tumours in dogs and cats. BMC Vet Res. 2009;5:39.
    • (2009) BMC Vet Res , vol.5 , pp. 39
    • Vascellari, M.1    Baioni, E.2    Ru, G.3
  • 43
    • 0020621166 scopus 로고
    • Prognostic factors in feline mammary carcinoma
    • K.WeijerA.A.M.Hart. Prognostic factors in feline mammary carcinoma. J Natl Cancer Inst. 1983;70:709–716.
    • (1983) J Natl Cancer Inst , vol.70 , pp. 709-716
    • Weijer, K.1    Hart, A.A.M.2
  • 44
    • 84890254448 scopus 로고    scopus 로고
    • Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update
    • A.C.WolffM.E.HammondD.G.Hicks. Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. J Clin Oncol. 2013;31:3997–4014.
    • (2013) J Clin Oncol , vol.31 , pp. 3997-4014
    • Wolff, A.C.1    Hammond, M.E.2    Hicks, D.G.3
  • 45
    • 75249083420 scopus 로고    scopus 로고
    • Ki67 in breast cancer: prognostic and predictive potential
    • R.YerushalmiR.WoodsP.M.Ravdin. Ki67 in breast cancer: prognostic and predictive potential. Lancet Oncol. 2010;11:174–183.
    • (2010) Lancet Oncol , vol.11 , pp. 174-183
    • Yerushalmi, R.1    Woods, R.2    Ravdin, P.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.