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Volumn 68, Issue 1, 2016, Pages 174-183

Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; STAT4 PROTEIN; UNTRANSLATED RNA; BLK PROTEIN, HUMAN; CASEIN KINASE II; CELL CYCLE PROTEIN; HLA DQ ANTIGEN; HLA-DQA1 ANTIGEN; HLA-DQB1 ANTIGEN; MSH5 PROTEIN, HUMAN; PROTEIN TYROSINE KINASE; STAT4 PROTEIN, HUMAN; TENASCIN; TENASCIN X; TRANSCRIPTOME;

EID: 84951988436     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39403     Document Type: Article
Times cited : (21)

References (50)
  • 1
    • 17244373451 scopus 로고    scopus 로고
    • Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort
    • on behalf of the Grupo Latinoamericano de Estudio del Lupus Eritematoso (GLADEL)
    • Alarcon-Segovia D, Alarcon-Riquelme ME, Cardiel MH, Caeiro F, Massardo L, Villa AR, et al, on behalf of the Grupo Latinoamericano de Estudio del Lupus Eritematoso (GLADEL). Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort. Arthritis Rheum 2005; 52: 1138-47.
    • (2005) Arthritis Rheum , vol.52 , pp. 1138-1147
    • Alarcon-Segovia, D.1    Alarcon-Riquelme, M.E.2    Cardiel, M.H.3    Caeiro, F.4    Massardo, L.5    Villa, A.R.6
  • 4
    • 84865473936 scopus 로고    scopus 로고
    • Genetic susceptibility to lupus: The biological basis of genetic risk found in B cell signaling pathways
    • Vaughn SE, Kottyan LC, Munroe ME, Harley JB., Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways. J Leukoc Biol 2012; 92: 577-91.
    • (2012) J Leukoc Biol , vol.92 , pp. 577-591
    • Vaughn, S.E.1    Kottyan, L.C.2    Munroe, M.E.3    Harley, J.B.4
  • 5
    • 84908387757 scopus 로고    scopus 로고
    • Genetics of systemic lupus erythematosus: Immune responses and end organ resistance to damage
    • Dai C, Deng Y, Quinlan A, Gaskin F, Tsao BP, Fu SM., Genetics of systemic lupus erythematosus: immune responses and end organ resistance to damage. Curr Opin Immunol 2014; 31: 87-96.
    • (2014) Curr Opin Immunol , vol.31 , pp. 87-96
    • Dai, C.1    Deng, Y.2    Quinlan, A.3    Gaskin, F.4    Tsao, B.P.5    Fu, S.M.6
  • 6
    • 40049108936 scopus 로고    scopus 로고
    • Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
    • Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, et al., Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008; 358: 900-9.
    • (2008) N Engl J Med , vol.358 , pp. 900-909
    • Hom, G.1    Graham, R.R.2    Modrek, B.3    Taylor, K.E.4    Ortmann, W.5    Garnier, S.6
  • 7
    • 38649125210 scopus 로고    scopus 로고
    • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
    • Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, et al., Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40: 204-10.
    • (2008) Nat Genet , vol.40 , pp. 204-210
    • Harley, J.B.1    Alarcon-Riquelme, M.E.2    Criswell, L.A.3    Jacob, C.O.4    Kimberly, R.P.5    Moser, K.L.6
  • 8
    • 50449111452 scopus 로고    scopus 로고
    • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
    • Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, et al., Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 1059-61.
    • (2008) Nat Genet , vol.40 , pp. 1059-1061
    • Graham, R.R.1    Cotsapas, C.2    Davies, L.3    Hackett, R.4    Lessard, C.J.5    Leon, J.M.6
  • 10
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
    • Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, et al., A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet 2009; 41: 1228-33.
    • (2009) Nat Genet , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3    Taylor, K.E.4    Chung, S.A.5    Sun, X.6
  • 11
    • 66149083275 scopus 로고    scopus 로고
    • Review of recent genome-wide association scans in lupus
    • Graham RR, Hom G, Ortmann W, Behrens TW., Review of recent genome-wide association scans in lupus. J Intern Med 2009; 265: 680-8.
    • (2009) J Intern Med , vol.265 , pp. 680-688
    • Graham, R.R.1    Hom, G.2    Ortmann, W.3    Behrens, T.W.4
  • 12
    • 84862959180 scopus 로고    scopus 로고
    • Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase
    • Jacob CO, Eisenstein M, Dinauer MC, Ming W, Liu Q, John S, et al., Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A 2012; 109: E59-67.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E59-E67
    • Jacob, C.O.1    Eisenstein, M.2    Dinauer, M.C.3    Ming, W.4    Liu, Q.5    John, S.6
  • 13
    • 84859491100 scopus 로고    scopus 로고
    • Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study
    • Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, et al., Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet 2012; 90: 648-60.
    • (2012) Am J Hum Genet , vol.90 , pp. 648-660
    • Lessard, C.J.1    Adrianto, I.2    Ice, J.A.3    Wiley, G.B.4    Kelly, J.A.5    Glenn, S.B.6
  • 14
    • 78650862201 scopus 로고    scopus 로고
    • Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study
    • Lessard CJ, Adrianto I, Kelly JA, Kaufman KM, Grundahl KM, Adler A, et al., Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet 2011; 88: 83-91.
    • (2011) Am J Hum Genet , vol.88 , pp. 83-91
    • Lessard, C.J.1    Adrianto, I.2    Kelly, J.A.3    Kaufman, K.M.4    Grundahl, K.M.5    Adler, A.6
  • 15
    • 79952261842 scopus 로고    scopus 로고
    • Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes
    • Taylor KE, Chung SA, Graham RR, Ortmann WA, Lee AT, Langefeld CD, et al., Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. PLoS Genet 2011; 7: e1001311.
    • (2011) PLoS Genet , vol.7 , pp. e1001311
    • Taylor, K.E.1    Chung, S.A.2    Graham, R.R.3    Ortmann, W.A.4    Lee, A.T.5    Langefeld, C.D.6
  • 16
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, Hu Z, et al., Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 2009; 41: 1234-7.
    • (2009) Nat Genet , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5    Hu, Z.6
  • 17
    • 84857487791 scopus 로고    scopus 로고
    • A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese
    • Okada Y, Shimane K, Kochi Y, Tahira T, Suzuki A, Higasa K, et al., A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet 2012; 8: e1002455.
    • (2012) PLoS Genet , vol.8 , pp. e1002455
    • Okada, Y.1    Shimane, K.2    Kochi, Y.3    Tahira, T.4    Suzuki, A.5    Higasa, K.6
  • 19
    • 77649206245 scopus 로고    scopus 로고
    • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    • Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, et al., Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet 2010; 6: e1000841.
    • (2010) PLoS Genet , vol.6 , pp. e1000841
    • Yang, W.1    Shen, N.2    Ye, D.Q.3    Liu, Q.4    Zhang, Y.5    Qian, X.X.6
  • 20
    • 84872328824 scopus 로고    scopus 로고
    • Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians
    • Yang W, Tang H, Zhang Y, Tang X, Zhang J, Sun L, et al., Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet 2013; 92: 41-51.
    • (2013) Am J Hum Genet , vol.92 , pp. 41-51
    • Yang, W.1    Tang, H.2    Zhang, Y.3    Tang, X.4    Zhang, J.5    Sun, L.6
  • 21
    • 84885633157 scopus 로고    scopus 로고
    • The development of genome-wide association studies and their application to complex diseases, including lupus
    • Bentham J, Vyse TJ., The development of genome-wide association studies and their application to complex diseases, including lupus. Lupus 2013; 22: 1205-13.
    • (2013) Lupus , vol.22 , pp. 1205-1213
    • Bentham, J.1    Vyse, T.J.2
  • 22
    • 84949097483 scopus 로고    scopus 로고
    • Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
    • E-pub ahead of print
    • Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, et al., Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nat Genet 2015. E-pub ahead of print.
    • (2015) Nat Genet
    • Bentham, J.1    Morris, D.L.2    Cunninghame Graham, D.S.3    Pinder, C.L.4    Tombleson, P.5    Behrens, T.W.6
  • 24
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [lettter]
    • for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology
    • Hochberg MC, for the Diagnostic and Therapeutic Criteria Committee of the American College of Rheumatology. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [lettter]. Arthritis Rheum 1997; 40: 1725.
    • (1997) Arthritis Rheum , vol.40 , pp. 1725
    • Hochberg, M.C.1
  • 26
    • 79953294312 scopus 로고    scopus 로고
    • Functional polymorphisms of the coagulation factor II gene (F2) and susceptibility to systemic lupus erythematosus
    • Demirci FY, Dressen AS, Kammerer CM, Barmada MM, Kao AH, Ramsey-Goldman R, et al., Functional polymorphisms of the coagulation factor II gene (F2) and susceptibility to systemic lupus erythematosus. J Rheumatol 2011; 38: 652-7.
    • (2011) J Rheumatol , vol.38 , pp. 652-657
    • Demirci, F.Y.1    Dressen, A.S.2    Kammerer, C.M.3    Barmada, M.M.4    Kao, A.H.5    Ramsey-Goldman, R.6
  • 27
    • 33750526654 scopus 로고    scopus 로고
    • A comparison of damage accrual across different calendar periods in systemic lupus erythematosus patients
    • Pineau CA, Bernatsky S, Abrahamowicz M, Neville C, Karp I, Clarke AE., A comparison of damage accrual across different calendar periods in systemic lupus erythematosus patients. Lupus 2006; 15: 590-4.
    • (2006) Lupus , vol.15 , pp. 590-594
    • Pineau, C.A.1    Bernatsky, S.2    Abrahamowicz, M.3    Neville, C.4    Karp, I.5    Clarke, A.E.6
  • 28
    • 58149467920 scopus 로고    scopus 로고
    • Differences in subclinical cardiovascular disease between African American and Caucasian women with systemic lupus erythematosus
    • Rhew EY, Manzi SM, Dyer AR, Kao AH, Danchenko N, Barinas-Mitchell E, et al., Differences in subclinical cardiovascular disease between African American and Caucasian women with systemic lupus erythematosus. Transl Res 2009; 153: 51-9.
    • (2009) Transl Res , vol.153 , pp. 51-59
    • Rhew, E.Y.1    Manzi, S.M.2    Dyer, A.R.3    Kao, A.H.4    Danchenko, N.5    Barinas-Mitchell, E.6
  • 29
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • Willer CJ, Li Y, Abecasis GR., METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 2010; 26: 2190-1.
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 30
    • 77953808087 scopus 로고    scopus 로고
    • Genotype imputation for genome-wide association studies
    • Marchini J, Howie B., Genotype imputation for genome-wide association studies. Nat Rev Genet 2010; 11: 499-511.
    • (2010) Nat Rev Genet , vol.11 , pp. 499-511
    • Marchini, J.1    Howie, B.2
  • 31
    • 84890172667 scopus 로고    scopus 로고
    • Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
    • Grundberg E, Meduri E, Sandling JK, Hedman AK, Keildson S, Buil A, et al., Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am J Hum Genet 2013; 93: 876-90.
    • (2013) Am J Hum Genet , vol.93 , pp. 876-890
    • Grundberg, E.1    Meduri, E.2    Sandling, J.K.3    Hedman, A.K.4    Keildson, S.5    Buil, A.6
  • 32
    • 84866871814 scopus 로고    scopus 로고
    • Mapping cis- and trans-regulatory effects across multiple tissues in twins
    • for the MuTHER consortium
    • Grundberg E, Small KS, Hedman AK, Nica AC, Buil A, Keildson S, et al, for the MuTHER consortium. Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 2012; 44: 1084-9.
    • (2012) Nat Genet , vol.44 , pp. 1084-1089
    • Grundberg, E.1    Small, K.S.2    Hedman, A.K.3    Nica, A.C.4    Buil, A.5    Keildson, S.6
  • 33
    • 77957232748 scopus 로고    scopus 로고
    • Genevar: A database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies
    • Yang TP, Beazley C, Montgomery SB, Dimas AS, Gutierrez-Arcelus M, Stranger BE, et al., Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies. Bioinformatics 2010; 26: 2474-6.
    • (2010) Bioinformatics , vol.26 , pp. 2474-2476
    • Yang, T.P.1    Beazley, C.2    Montgomery, S.B.3    Dimas, A.S.4    Gutierrez-Arcelus, M.5    Stranger, B.E.6
  • 34
    • 84855267424 scopus 로고    scopus 로고
    • Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans
    • Rotival M, Zeller T, Wild PS, Maouche S, Szymczak S, Schillert A, et al., Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet 2011; 7: e1002367.
    • (2011) PLoS Genet , vol.7 , pp. e1002367
    • Rotival, M.1    Zeller, T.2    Wild, P.S.3    Maouche, S.4    Szymczak, S.5    Schillert, A.6
  • 35
    • 38649138296 scopus 로고    scopus 로고
    • Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus
    • Kozyrev SV, Abelson AK, Wojcik J, Zaghlool A, Linga Reddy MV, Sanchez E, et al., Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 211-6.
    • (2008) Nat Genet , vol.40 , pp. 211-216
    • Kozyrev, S.V.1    Abelson, A.K.2    Wojcik, J.3    Zaghlool, A.4    Linga Reddy, M.V.5    Sanchez, E.6
  • 36
    • 79952787492 scopus 로고    scopus 로고
    • Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus
    • Sheng YJ, Gao JP, Li J, Han JW, Xu Q, Hu WL, et al., Follow-up study identifies two novel susceptibility loci PRKCB and 8p11.21 for systemic lupus erythematosus. Rheumatology (Oxford) 2011; 50: 682-8.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 682-688
    • Sheng, Y.J.1    Gao, J.P.2    Li, J.3    Han, J.W.4    Xu, Q.5    Hu, W.L.6
  • 39
    • 84881478367 scopus 로고    scopus 로고
    • A long noncoding RNA mediates both activation and repression of immune response genes
    • Carpenter S, Aiello D, Atianand MK, Ricci EP, Gandhi P, Hall LL, et al., A long noncoding RNA mediates both activation and repression of immune response genes. Science 2013; 341: 789-92.
    • (2013) Science , vol.341 , pp. 789-792
    • Carpenter, S.1    Aiello, D.2    Atianand, M.K.3    Ricci, E.P.4    Gandhi, P.5    Hall, L.L.6
  • 41
    • 84893818867 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway
    • Gu Z, Tan W, Feng G, Meng Y, Shen B, Liu H, et al., Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway. Mol Cell Biochem 2014; 387: 27-37.
    • (2014) Mol Cell Biochem , vol.387 , pp. 27-37
    • Gu, Z.1    Tan, W.2    Feng, G.3    Meng, Y.4    Shen, B.5    Liu, H.6
  • 42
    • 84874771771 scopus 로고    scopus 로고
    • Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases
    • Tuller T, Atar S, Ruppin E, Gurevich M, Achiron A., Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases. Genes Immun 2013; 14: 67-82.
    • (2013) Genes Immun , vol.14 , pp. 67-82
    • Tuller, T.1    Atar, S.2    Ruppin, E.3    Gurevich, M.4    Achiron, A.5
  • 43
    • 79551676333 scopus 로고    scopus 로고
    • Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development
    • Tveita AA, Rekvig OP., Alterations in Wnt pathway activity in mouse serum and kidneys during lupus development. Arthritis Rheum 2011; 63: 513-22.
    • (2011) Arthritis Rheum , vol.63 , pp. 513-522
    • Tveita, A.A.1    Rekvig, O.P.2
  • 44
    • 55049083176 scopus 로고    scopus 로고
    • A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome
    • Bassuk AG, Wallace RH, Buhr A, Buller AR, Afawi Z, Shimojo M, et al., A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome. Am J Hum Genet 2008; 83: 572-81.
    • (2008) Am J Hum Genet , vol.83 , pp. 572-581
    • Bassuk, A.G.1    Wallace, R.H.2    Buhr, A.3    Buller, A.R.4    Afawi, Z.5    Shimojo, M.6
  • 45
    • 84892383122 scopus 로고    scopus 로고
    • Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders
    • Cukier HN, Dueker ND, Slifer SH, Lee JM, Whitehead PL, Lalanne E, et al., Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders. Mol Autism 2014; 5: 1.
    • (2014) Mol Autism , vol.5 , pp. 1
    • Cukier, H.N.1    Dueker, N.D.2    Slifer, S.H.3    Lee, J.M.4    Whitehead, P.L.5    Lalanne, E.6
  • 46
    • 79851516501 scopus 로고    scopus 로고
    • Mutations in prickle orthologs cause seizures in flies, mice, and humans
    • Tao H, Manak JR, Sowers L, Mei X, Kiyonari H, Abe T, et al., Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet 2011; 88: 138-49.
    • (2011) Am J Hum Genet , vol.88 , pp. 138-149
    • Tao, H.1    Manak, J.R.2    Sowers, L.3    Mei, X.4    Kiyonari, H.5    Abe, T.6
  • 47
    • 55349142293 scopus 로고    scopus 로고
    • IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
    • Isnardi I, Ng YS, Srdanovic I, Motaghedi R, Rudchenko S, von Bernuth H, et al., IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 2008; 29: 746-57.
    • (2008) Immunity , vol.29 , pp. 746-757
    • Isnardi, I.1    Ng, Y.S.2    Srdanovic, I.3    Motaghedi, R.4    Rudchenko, S.5    Von Bernuth, H.6
  • 48
    • 68949094003 scopus 로고    scopus 로고
    • IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease
    • Staschke KA, Dong S, Saha J, Zhao J, Brooks NA, Hepburn DL, et al., IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease. J Immunology 2009; 183: 568-77.
    • (2009) J Immunology , vol.183 , pp. 568-577
    • Staschke, K.A.1    Dong, S.2    Saha, J.3    Zhao, J.4    Brooks, N.A.5    Hepburn, D.L.6
  • 49
    • 79251552829 scopus 로고    scopus 로고
    • Immune complex-mediated cell activation from systemic lupus erythematosus and rheumatoid arthritis patients elaborate different requirements for IRAK1/4 kinase activity across human cell types
    • Chiang EY, Yu X, Grogan JL., Immune complex-mediated cell activation from systemic lupus erythematosus and rheumatoid arthritis patients elaborate different requirements for IRAK1/4 kinase activity across human cell types. J Immunol 2011; 186: 1279-88.
    • (2011) J Immunol , vol.186 , pp. 1279-1288
    • Chiang, E.Y.1    Yu, X.2    Grogan, J.L.3
  • 50
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identification of trans eQTLs as putative drivers of known disease associations
    • Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, et al., Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet 2013; 45: 1238-43.
    • (2013) Nat Genet , vol.45 , pp. 1238-1243
    • Westra, H.J.1    Peters, M.J.2    Esko, T.3    Yaghootkar, H.4    Schurmann, C.5    Kettunen, J.6


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