In vivo monitoring of urea cycle activity with 13C-acetate as a tracer of ureagenesis

Molecular Genetics and Metabolism

Volumn 117, Issue 1, 2016, Pages 19-26

  Opladen, Thomas ^a   Lindner, Martin ^a,b   Das, Anibh M ^c   Marquardt, Thorsten ^d   Khan, Aneal ^e   Emre, Sukru H ^f   Burton, Barbara K ^g   Barshop, Bruce A ^h   Böhm, Thea ⁱ   Meyburg, Jochen ^a   Zangerl, Kathrin ^a   Mayorandan, Sebene ^c   Burgard, Peter ^a   Dürr, Ulrich H N ⁱ   Rosenkranz, Bernd ^j   Rennecke, Jörg ⁱ   Derbinski, Jens ⁱ   Yudkoff, Marc ^k   Hoffmann, Georg F ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^e ALBERTA CHILDREN'S HOSPITAL   (Canada)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g CHILDREN'S MEMORIAL HOSPITAL   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ Cytonet GmbH and Co KG   (Germany)

^j UNIVERSITY OF STELLENBOSCH   (South Africa)

^k CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

more..

Author keywords

13C stable isotope; Sodium 1,2 13C acetate; UCD; Urea cycle defect; Ureagenesis

Indexed keywords

SODIUM ACETATE C 13; TRACER; UNCLASSIFIED DRUG; UREA; ACETIC ACID; CARBON;

ABDOMINAL PAIN; ADULT; AGED; AREA UNDER THE CURVE; ARGININOSUCCINATE SYNTHETASE 1 DEFICIENCY; ARGININOSUCCINIC ACIDURIA; ARTICLE; ASYMPTOMATIC DISEASE; CARBAMOYL PHOSPHATE SYNTHETASE I DEFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; DIZZINESS; FEMALE; GENE MUTATION; HEADACHE; HUMAN; HYPOTENSION; IN VIVO STUDY; MALAISE; MALE; NAUSEA; ORNITHINE TRANSCARBAMYLASE DEFICIENCY; PRIORITY JOURNAL; SINGLE DRUG DOSE; THROMBOPHLEBITIS; UREA BLOOD LEVEL; UREA CYCLE; UREA CYCLE DISORDER; ADOLESCENT; CHILD; EVALUATION STUDY; HYPERAMMONEMIA; INFANT; METABOLISM; MIDDLE AGED; NEWBORN; ORAL DRUG ADMINISTRATION; ORNITHINE CARBAMOYLTRANSFERASE DEFICIENCY DISEASE; PHYSIOLOGIC MONITORING; PRESCHOOL CHILD; UREA CYCLE DISORDERS, INBORN; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; CARBON ISOTOPES; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPERAMMONEMIA; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; MONITORING, PHYSIOLOGIC; ORNITHINE CARBAMOYLTRANSFERASE DEFICIENCY DISEASE; RADIOACTIVE TRACERS; SODIUM ACETATE; UREA; UREA CYCLE DISORDERS, INBORN; YOUNG ADULT;

EID: 84951831390     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2015.11.007     Document Type: Article

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