Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast-like synovial cells through high mobility group box chromosomal protein 1

Arthritis Research and Therapy

Volumn 17, Issue 1, 2015, Pages

  Xu, Ke ^a   Cai, Yong song ^a   Lu, She Min ^a   Li, Xiao li ^a   Liu, Lin ^a   Li, Zhong ^a   Liu, Hui ^a   Xu, Peng ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Fibroblast like synovial cells; Methotrexate; Rheumatoid arthritis

Indexed keywords

BECLIN 1; CASPASE; HIGH MOBILITY GROUP B1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; METHOTREXATE; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTIRHEUMATIC AGENT; HMGB1 PROTEIN, HUMAN;

ADULT; AGED; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL ISOLATION; CELL STIMULATION; CELL VIABILITY; CLINICAL ARTICLE; DRUG EXPOSURE; DRUG SENSITIVITY; FEMALE; FIBROBLAST LIKE SYNOVIAL CELL; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MALE; MTT ASSAY; OSTEOARTHRITIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; ARTHRITIS, RHEUMATOID; BIOSYNTHESIS; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; DRUG RESISTANCE; FIBROBLAST; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SYNOVIUM;

AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; AUTOPHAGY; BLOTTING, WESTERN; CELL SURVIVAL; DRUG RESISTANCE; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; HMGB1 PROTEIN; HUMANS; MALE; METHOTREXATE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; RNA, SMALL INTERFERING; SYNOVIAL MEMBRANE; TRANSFECTION;

EID: 84951807395     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0892-y     Document Type: Article

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