Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer

EBioMedicine

Volumn 2, Issue 7, 2015, Pages 681-689

  Candido dos Reis, Francisco J ^a,b   Lynn, Stuart ^c   Ali, H Raza ^d   Eccles, Diana ^e   Hanby, Andrew ^f   Provenzano, Elena ^g   Caldas, Carlos ^d   Howat, William J ^d   McDuffus, Leigh Anne ^d   Liu, Bin ^d   Daley, Frances ^h   Coulson, Penny ^h   Vyas, Rupesh J ^d   Harris, Leslie M ^d   Owens, Joanna M ^d   Carton, Amy F M ^d   McQuillan, Janette P ^d   Paterson, Andy M ^d   Hirji, Zohra ^d   Christie, Sarah K ^d   Holmes, Amber R ^d   Schmidt, Marjanka K ⁱ   Garcia Closas, Montserrat ^h   Easton, Douglas F ^a   Bolla, Manjeet K ^a   Wang, Qin ^a   Benitez, Javier ^j,k   Milne, Roger L ^l,m   Mannermaa, Arto ⁿ   Couch, Fergus ^o   Devilee, Peter ^p   Tollenaar, Robert A E M ^p   Seynaeve, Caroline ^c   Cox, Angela ^q   Cross, Simon S ^q   Blows, Fiona M ^a   Sanders, Joyce ⁱ   de Groot, Renate ⁱ   Figueroa, Jonine ^r   Sherman, Mark ^r   Hooning, Maartje ^s   Brenner, Hermann ^t   Holleczek, Bernd ^u   Stegmaier, Christa ^u   Lintott, Chris ^c   Pharoah, Paul D P ^a   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^f UNIVERSITY OF LEEDS   (United Kingdom)

^g ADDENBROOKE S HOSPITAL   (United Kingdom)

^h INSTITUTE OF CANCER RESEARCH   (United Kingdom)

ⁱ ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^j Centro Nacional de Investigaciones Oncológicas   (Spain)

^k CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

^l CANCER EPIDEMIOLOGY CENTRE   (Australia)

^m UNIVERSITY OF MELBOURNE   (Australia)

ⁿ UNIVERSITY OF EASTERN FINLAND   (Finland)

^o MAYO CLINIC   (United States)

^p LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^q UNIVERSITY OF SHEFFIELD   (United Kingdom)

^r NATIONAL CANCER INSTITUTE   (United States)

^s ERASMUS MC CANCER INSTITUTE   (Netherlands)

^t GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^u SAARLAND CANCER REGISTRY   (Germany)

more..

Author keywords

Breast cancer; Citizen science; Crowd science; Crowdsourcing

Indexed keywords

ESTROGEN RECEPTOR; TUMOR MARKER;

ARTICLE; CANCER SURVIVAL; CLINICAL PRACTICE; CORRELATION COEFFICIENT; CROWDSOURCING; DISEASE ASSESSMENT; FOLLOW UP; HUMAN; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MATHEMATICAL MODEL; MEASUREMENT ACCURACY; MEDICAL RECORD REVIEW; MOLECULAR PATHOLOGY; NEOPLASM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; TISSUE MICROARRAY; BREAST TUMOR; FEMALE; KAPLAN MEIER METHOD; METABOLISM; MORTALITY; PATHOLOGY; PROPORTIONAL HAZARDS MODEL;

BREAST NEOPLASMS; CROWDSOURCING; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; PATHOLOGY, MOLECULAR; PROPORTIONAL HAZARDS MODELS; RECEPTORS, ESTROGEN; ROC CURVE;

EID: 84951573783     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.05.009     Document Type: Article

References (25)

1. Ali A.M., Dawson S.J., Blows F.M., Provenzano E., Ellis I.O., Baglietto L., Huntsman D., Caldas C., Pharoah P.D. Comparison of methods for handling missing data on immunohistochemical markers in survival analysis of breast cancer. Br. J. Cancer 2011, 104(4):693-699.
2. Ali H.R., Irwin M., Morris L., Dawson S.J., Blows F.M., Provenzano E., Mahler-Araujo B., Pharoah P.D., Walton N.A., Brenton J.D., Caldas C. Astronomical algorithms for automated analysis of tissue protein expression in breast cancer. Br. J. Cancer 2013, 108(3):602-612.
3. Ali H.R., Provenzano E., Dawson S.J., Blows F.M., Liu B., Shah M., Earl H.M., Poole C.J., Hiller L., Dunn J.A., Bowden S.J., Twelves C., Bartlett J.M., Mahmoud S.M., Rakha E., Ellis I.O., Liu S., Gao D., Nielsen T.O., Pharoah P.D., Caldas C. Association between CD8+ T-cell infiltration and breast cancer survival in 12,439 patients. Ann. Oncol. 2014, 25(8):1536-1543.
4. Badve S.S., Baehner F.L., Gray R.P., Childs B.H., Maddala T., Liu M.L., Rowley S.C., Shak S., Perez E.A., Perez E.D., Shulman L.J., Martino S., Davidson N.E., Sledge G.W., Goldstein L.J., Sparano J.A. Estrogen- and progesterone-receptor status in ECOG 2197: comparison of immunohistochemistry by local and central laboratories and quantitative reverse transcription polymerase chain reaction by central laboratory. J. Clin. Oncol. 2008, 26(15):2473-2481.
5. Blows F.M., Driver K.E., Schmidt M.K., Broeks A., van Leeuwen F.E., Wesseling J., Cheang M.C., Gelmon K., Nielsen T.O., Blomqvist C., Heikkilä P., Heikkinen T., Nevanlinna H., Akslen L.A., Bégin L.R., Foulkes W.D., Couch F.J., Wang X., Cafourek V., Olson J.E., Baglietto L., Giles G.G., Severi G., McLean C.A., Southey M.C., Rakha E., Green A.R., Ellis I.O., Sherman M.E., Lissowska J., Anderson W.F., Cox A., Cross S.S., Reed M.W., Provenzano E., Dawson S.J., Dunning A.M., Humphreys M., Easton D.F., García-Closas M., Caldas C., Pharoah P.D., Huntsman D. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Med. 2010, 7(5):e1000279.
6. Bolton K.L., Garcia-Closas M., Pfeiffer R.M., Duggan M.A., Howat W.J., Hewitt S.M., Yang X.R., Cornelison R., Anzick S.L., Meltzer P., Davis S., Lenz P., Figueroa J.D., Pharoah P.D., Sherman M.E. Assessment of automated image analysis of breast cancer tissue microarrays for epidemiologic studies. Cancer Epidemiol. Biomarkers Prev. 2010, 19(4):992-999.
7. Breast Cancer Association Consortium Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium. J. Natl. Cancer Inst. 2006, 98(19):1382-1396.
8. Camp R.L., Neumeister V., Rimm D.L. A decade of tissue microarrays: progress in the discovery and validation of cancer biomarkers. J. Clin. Oncol. 2008, 26(34):5630-5637.
9. Cooper S., Khatib F., Treuille A., Barbero J., Lee J., Beenen M., Leaver-Fay A., Baker D., Popović Z., Players F. Predicting protein structures with a multiplayer online game. Nature 2010, 466(7307):756-760.
10. Giltnane J.M., Rimm D.L. Technology insight: identification of biomarkers with tissue microarray technology. Nat. Clin. Pract. Oncol. 2004, 1(2):104-111.
11. Graham J.W., Olchowski A.E., Gilreath T.D. How many imputations are really needed? Some practical clarifications of multiple imputation theory. Prev. Sci. 2007, 8(3):206-213.
12. Harvey J.M., Clark G.M., Osborne C.K., Allred D.C. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J. Clin. Oncol. 1999, 17(5):1474-1481.
13. Howat W.J., Blows F.M., Provenzano E., Brook M.N., Morris L., Gazinska P., Johnson N., McDuffus L.-A., Miller J., Sawyer E.J., Pinder S., van Deurzen C.H.M., Jones L., Sironen R., Visscher D., Caldas C., Daley F., Coulson P., Broeks A., Sanders J., Wesseling J., Nevanlinna H., Fagerholm R., Blomqvist C., Heikkilä P., Ali H.R., Dawson S.-J., Figueroa J., Lissowska J., Brinton L., Mannermaa A., Kataja V., Kosma V.-M., Cox A., Brock I.W., Cross S.S., Reed M.W., Couch F.J., Olson J.E., Devillee P., Mesker W.E., Seyaneve C.M., Hollestelle A., Benitez J., Perez J.I.A., Menéndez P., Bolla M.K., Easton D.F., Schmidt M.K., Pharoah P.D., Sherman M.E., García-Closas M. Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium. J. Pathol. Clin. Res. 2015, 1(1):18-32.
14. Howe J. Crowdsourcing: a definition (Accessed: May 16th 2014 2014). http://crowdsourcing.typepad.com/cs/2006/06/crowdsourcing_a.html.
15. Kawrykow A., Roumanis G., Kam A., Kwak D., Leung C., Wu C., Zarour E., Sarmenta L., Blanchette M., Waldispühl J., Players P. Phylo: a citizen science approach for improving multiple sequence alignment. PLoS One 2012, 7(3):e31362.
16. Kononen J., Bubendorf L., Kallioniemi A., Bärlund M., Schraml P., Leighton S., Torhorst J., Mihatsch M.J., Sauter G., Kallioniemi O.P. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat. Med. 1998, 4(7):844-847.
17. Lesueur F., Pharoah P.D., Laing S., Ahmed S., Jordan C., Smith P.L., Luben R., Wareham N.J., Easton D.F., Dunning A.M., Ponder B.A. Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer. Hum. Mol. Genet. 2005, 14(16):2349-2356.
18. Lintott C., Schawinski K., Slosar A., Land K., Bamford S., Thomas D., Raddick M., Nichol R., Szalay A., Andreescu D., Murray P., Vandenberg J. Galaxy Zoo: morphologies derived from visual inspection of galaxies from the Sloan Digital Sky Survey. Mon. Not. R. Astron. Soc. 2008, 389(3):1179-1189.
19. Mattingly K., Ponsonby A.L. A consideration of group work processes in modern epidemiology. Ann. Epidemiol. 2014, 24(4):319-323.
20. Page S.E. The Difference: How the Power of Diversity Creates Better Groups, Firms, Schools, and Societies 2008, vol. 456. Princeton University Press, Princeton, NJ.
21. Pierdominici M., Maselli A., Colasanti T., Giammarioli A.M., Delunardo F., Vacirca D., Sanchez M., Giovannetti A., Malorni W., Ortona E. Estrogen receptor profiles in human peripheral blood lymphocytes. Immunol. Lett. 2010, 132(1-2):79-85.
22. Rubin D.B. Inference and missing data. Biometrika 1976, 63(3):581-592.
23. Starr J., Schweik C.M., Bush N., Fletcher L., Finn J., Fish J., Bargeron C.T. Lights, camera...citizen science: assessing the effectiveness of smartphone-based video training in invasive plant identification. PLoS One 2014, 9(11):e111433.
24. Wan W.H., Fortuna M.B., Furmanski P. A rapid and efficient method for testing immunohistochemical reactivity of monoclonal antibodies against multiple tissue samples simultaneously. J. Immunol. Methods 1987, 103(1):121-129.
25. White I.R., Royston P., Wood A.M. Multiple imputation using chained equations: issues and guidance for practice. Stat. Med. 2011, 30(4):377-399.