Is Psychosis a Disorder of XY Epigenetics?

EBioMedicine

Volumn 2, Issue 8, 2015, Pages 794-795

  Crow, Timothy J ^a  

^a WARNEFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

47,XXX SYNDROME; ANATOMICAL VARIATION; ANXIETY; AUTISM; BRAIN ASYMMETRY; BRAIN GROWTH; EPIGENETIC REPRESSION; GENETIC ASSOCIATION; GENETIC LINKAGE; HEMISPHERIC DOMINANCE; HUMAN; KLINEFELTER SYNDROME; NOTE; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; PSYCHOSIS; SEX CHROMOSOME ABERRATION; SUBSTANCE ABUSE; TURNER SYNDROME; FEMALE; GENETIC EPIGENESIS; GENETIC VARIATION; GENETICS; MALE; METABOLISM; X CHROMOSOME; Y CHROMOSOME;

CHROMOSOMES, HUMAN, X; CHROMOSOMES, HUMAN, Y; EPIGENESIS, GENETIC; FEMALE; GENETIC VARIATION; HUMANS; MALE; PSYCHOTIC DISORDERS;

EID: 84951573323     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.06.015     Document Type: Note

References (10)

1. Bora E., Fornito A., Yuecel M., Pantelis C. The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder. Psychol. Med. 2012, 42:295-307. 10.1017/s0033291711001450.
2. Crow T.J. The case for an X-Y homologous determinant of cerebral asymmetry. Cytogenet. Cell Genet. 1994, 67:393-394.
3. Crow T.J. The 'big bang' theory of the origin of psychosis and the faculty of language. Schizophr. Res. 2008, 102:31-52. 10.1016/j.schres.2008.03.010.
4. Goodkind M., Eickhoff S.B., Oathes D.J., et al. Identification of a common neurobiological substrate for mental illness. JAMA Psychiatry 2015, 10.1001/jamapsychiatry.2014.2206.
5. Ji B., Higa K.K., Kelsoe J.R., Zhou X. Over-expression of XIST, the master gene for X chromosome inactivation, in females with major affective disorders. EBio. Med. 2015, 2:907-916.
6. Lin A., et al. Mapping the stability of human brain asymmetry across five sex-chromosome aneuploidies. J. Neurosci. 2015, 35:140-145. 10.1523/JNeurosci.3489-14.2015.
7. Pletikos M., et al. Temporal specification and bilaterality of human neocortical topographic gene expression. Neuron 2014, 81:321-332. 10.1016/j.neuron.2013.11.018.
8. Power R.A., et al. Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings. JAMA Psychiatry 2013, 70:22-30. 10.1001/jamapsychiatry.2013.268.
9. Rezaie R., et al. The influence of sex chromosome aneuploidy on brain asymmetry. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009, 150B:74-85. 10.1002/ajmg.b.30772.
10. Williams N.A., Close J., Giouzeli M., Crow T.J. Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2006, 141B:623-633.