Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology

Epilepsia

Volumn 56, Issue 12, 2015, Pages e198-e202

  Furman, Moran ^a   Zhan, Qiong ^a,b   McCafferty, Cian ^a   Lerner, Benjamin A ^a   Motelow, Joshua E ^a   Meng, Jin ^a   Ma, Chanthia ^a   Buchanan, Gordon F ^a   Witten, Ilana B ^c   Deisseroth, Karl ^d   Cardin, Jessica A ^a   Blumenfeld, Hal ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c PRINCETON UNIVERSITY   (United States)

^d Stanford University   (United States)

Author keywords

Acetylcholine; Consciousness; Epilepsy; Neurostimulation; Optogenetics; Sudden unexpected death in epilepsy (SUDEP)

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AROUSAL; ARTICLE; BRAIN DYSFUNCTION; BRAIN STEM; CHOLINERGIC NERVE CELL; CHOLINERGIC STIMULATION; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DELTA RHYTHM; FEMALE; GAMMA RHYTHM; MALE; NEUROPHYSIOLOGY; NONHUMAN; OPTOGENETICS; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PRIORITY JOURNAL; RAT; SLEEP; UNCONSCIOUSNESS; ANIMAL; BRAIN CORTEX; DISEASE MODEL; LIMBIC CORTEX; LONG EVANS RAT; METABOLISM; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; PROCEDURES; SEIZURE;

CHANNELRHODOPSIN 2, RAT; RHODOPSIN;

ANIMALS; BRAIN STEM; CEREBRAL CORTEX; CHOLINERGIC NEURONS; DISEASE MODELS, ANIMAL; FEMALE; LIMBIC LOBE; MALE; OPTOGENETICS; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PHOTIC STIMULATION; RATS; RATS, LONG-EVANS; RHODOPSIN; SEIZURES;

EID: 84951568913     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.13220     Document Type: Article

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