Mapping tissue inhomogeneity in acute myocarditis: A novel analytical approach to quantitative myocardial edema imaging by T2-mapping

Journal of Cardiovascular Magnetic Resonance

Volumn 17, Issue 1, 2015, Pages

  Baeßler, Bettina ^a   Schaarschmidt, Frank ^b   Dick, Anastasia ^a   Stehning, Christian ^c   Schnackenburg, Bernhard ^c   Michels, Guido ^a   Maintz, David ^a   Bunck, Alexander C ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^c PHILIPS RESEARCH LABORATORIES   (Germany)

Author keywords

Acute myocarditis; Cardiovascular magnetic resonance; Myocardial edema; T2 mapping; Tissue characterization

Indexed keywords

ACUTE DISEASE; ADULT; AGED; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HEART EDEMA; HUMAN; MALE; MYOCARDITIS; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; TISSUE CHARACTERIZATION; BREATH HOLDING; CARDIAC MUSCLE; CINE MAGNETIC RESONANCE IMAGING; COMPUTER ASSISTED DIAGNOSIS; FIBROSIS; MIDDLE AGED; PATHOLOGY; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; RETROSPECTIVE STUDY; YOUNG ADULT;

ACUTE DISEASE; ADULT; AGED; BREATH HOLDING; EDEMA, CARDIAC; FEMALE; FIBROSIS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDITIS; MYOCARDIUM; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84951274071     PISSN: 10976647     EISSN: 1532429X     Source Type: Journal    
DOI: 10.1186/s12968-015-0217-y     Document Type: Article

References (41)

1. Cooper LT, Fairweather D. We see only what we look for: imaging cardiac inflammation. Circ Cardiovasc Imaging. 2013;6:165-6.
2. Greulich S, Ferreira VM, Dall'Armellina E, Mahrholdt H. Myocardial Inflammation-Are We There Yet? Curr Cardiovasc Imaging Rep. 2015;8:6-11.
3. Park CH, Choi E-Y, Greiser A, Paek MY, Hwang SH, Kim TH. Diagnosis of acute global myocarditis using cardiac MRI with quantitative t1 and t2 mapping: case report and literature review. Korean J Radiol. 2013;14:727-32.
4. Buser PT. Prediction of LV functional recovery by CMR in myocarditis: bright signals - bright answers? Eur Heart J Cardiovasc Imaging. 2014;15:1177-8.
5. Francone M, Chimenti C, Galea N, Scopelliti F, Verardo R, Galea R, et al. CMR sensitivity varies with clinical presentation and extent of cell necrosis in biopsy-proven acute myocarditis. J Am Coll Cardiol Img. 2014;7:254-63.
6. Friedrich MG, Sechtem U, Schulz-Menger J, Holmvang G, Alakija P, Cooper LT, et al. Cardiovascular Magnetic Resonance in Myocarditis: A JACC White Paper. J Am Coll Cardiol. 2009;53:1475-87.
7. Thavendiranathan P, Walls M, Giri S, Verhaert D, Rajagopalan S, Moore S, et al. Improved detection of myocardial involvement in acute inflammatory cardiomyopathies using T2 mapping. Circ Cardiovasc Imaging. 2012;5:102-10.
8. Giri S, Chung Y-C, Merchant A, Mihai G, Rajagopalan S, Raman SV, et al. T2 quantification for improved detection of myocardial edema. J Cardiovasc Magn Reson. 2009;11:56.
9. Baeßler B, Schaarschmidt F, Stehning C, Schnackenburg B, Maintz D, Bunck AC. A systematic evaluation of three different cardiac T2-mapping sequences at 1.5 and 3 T in healthy volunteers. Eur J Radiol. 2015;84:2161-70.
10. Verhaert D, Thavendiranathan P, Giri S, Mihai G, Rajagopalan S, Simonetti OP, et al. Direct T2 quantification of myocardial edema in acute ischemic injury. J Am Coll Cardiol Img. 2011;4:269-78.
11. Baeßler B, Schaarschmidt F, Stehning C, Schnackenburg B, Maintz D, Bunck AC. Cardiac T2-mapping using a fast gradient echo spin echo sequence - first in vitro and in vivo experience. J Cardiovasc Magn Reson. 2015;17:67.
12. Caforio ALP, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013;34:2636-48.
13. Cocker MS, Strohm O, Smith DJ, Butler C, Belenkie I, Meeuwisse W, et al. Sub-clinical systolic dysfunction with persistent myocardial edema and inflammation in elite high-endurance athletes with common colds: a cardiovascular magnetic resonance study. J Cardiovasc Magn Reson. 2009;11:O3.
14. Zagrosek A, Messroghli D, Schulz O, Dietz R, Schulz-Menger J. Effect of binge drinking on the heart as assessed by cardiac magnetic resonance imaging. JAMA. 2010;304:1328-30.
15. Simonetti OP, Finn JP, White RD, Laub G, Henry DA. "Black blood" T2-weighted inversion-recovery MR imaging of the heart. Radiology. 1996;199:49-57.
16. Friedrich MGM, Strohm OO, Schulz-Menger JJ, Marciniak HH, Luft FCF, Dietz RR. Contrast media-enhanced magnetic resonance imaging visualizes myocardial changes in the course of viral myocarditis. Circulation. 1998;97:1802-9.
17. Kramer CM, Barkhausen J, Flamm SD, Kim RJ, Nagel E, Society for Cardiovascular Magnetic Resonance Board of Trustees Task Force on Standardized Protocols. Standardized cardiovascular magnetic resonance imaging (CMR) protocols, society for cardiovascular magnetic resonance: board of trustees task force on standardized protocols. J Cardiovasc Magn Reson. 2008;10:35.
18. Feinberg DA, Oshio K. GRASE (gradient- and spin-echo) MR imaging: a new fast clinical imaging technique. Radiology. 1991;181:597-602.
19. 2 mapping at 3 T: reference values, influencing factors and implications. J Cardiovasc Magn Reson. 2013;15:1-1.
20. Payne AR, Casey M, McClure J, McGeoch R, Murphy A, Woodward R, et al. Bright-blood T2-weighted MRI has higher diagnostic accuracy than dark-blood short tau inversion recovery MRI for detection of acute myocardial infarction and for assessment of the ischemic area at risk and myocardial salvage. Circ Cardiovasc Imaging. 2011;4:210-9.
21. Cerqueira MD, Verani MS, Schwaiger M, Heo J, Iskandrian AS. Safety profile of adenosine stress perfusion imaging: results from the Adenoscan Multicenter Trial Registry. J Am Coll Cardiol. 1994;23:384-9.
22. Abdel-Aty H, Boyé P, Zagrosek A, Wassmuth R, Kumar A, Messroghli D, et al. Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis: comparison of different approaches. J Am Coll Cardiol. 2005;45:1815-22.
23. Friedrich MG, Marcotte F. Cardiac magnetic resonance assessment of myocarditis. Circ Cardiovasc Imaging. 2013;6:833-9.
24. R Core Team: R: A language and environment for statistical computing. R Foundation for Statistical Computing. Available at: http://www.R-project.org/. Accessed November 2015.
25. Wickham H, Chang W: ggplot2: An implementation of the Grammar of Graphics. Available at: http://ggplot2.org. Accessed November 2015.
26. Grosjean P, Ibanez F, Etienne M: Pastecs: Package for Analysis of Space-Time Ecological Series. Available at: https://cran.r-project.org/web/packages/pastecs/. Accessed November 2015.
27. Maindonald JH, Braun WJ: DAAG: Data Analysis And Graphics data and functions. Available at: http://www.stats.uwo.ca/DAAG. Accessed November 2015.
28. Liaw A, Wiener M, Breiman L, Cutler A: randomForest: Breiman and Cutler's random forests for classification and regression. Available at: https://www.stat.berkeley.edu/~breiman/RandomForests/cc-home.htm. Accessed November 2015.
29. Therneau T, Atkinson B, Ripley B: Recursive Partitioning and Regression Trees. http://www.R-project.org/. Accessed November 2015.
30. Breiman L, Friedman J, Stone CJ, Olshen RA. Classification and Regression Trees. 1st ed. Belmont: Chapman and Hall/CRC; 1984.
31. Sing T, Sander O, Beerenwinkel N, Lengauer T: ROCR: Visualizing the performance of scoring classifiers. Available at: http://rocr.bioinf.mpi-sb.mpg.de/. Accessed November 2015.
32. Butler CR, Savu A, Bakal JA, Toma M, Thompson R, Chow K, et al. Correlation of Cardiovascular MRI Findings and Endomyocardial Biopsy Results in Patients Undergoing Screening for Heart Transplant RejectionCardiovascular MRI and Heart Transplant Rejection. J Heart Lung Transplant. 2015;34(5):643-50.
33. Radunski UK, Bohnen S, Lund G, Säring D, Stehning C, Schnackenburg B, et al. T1 and T2 mapping CMR to quantify focal myocardial injury in patients with myocarditis. J Cardiovasc Magn Reson. 2015;17:O90.
34. Bönner F, Spieker M, Stanske B, Haberkorn SM, Butzbach B, Horn P, et al. T2-Mapping CMR increases the diagnostic sensitivity for detection of myocardial inflammation in patients with possible myocarditis - a prospective endomyocardial biopsy-controlled study. J Cardiovasc Magn Reson. 2015;17:P319.
35. Wassmuth R, Prothmann M, Utz W, Dieringer M, von Knobelsdorff-Brenkenhoff F, Greiser A, et al. Variability and homogeneity of cardiovascular magnetic resonance myocardial T2-mapping in volunteers compared to patients with edema. J Cardiovasc Magn Reson. 2013;15:27.
36. Radunski UK, Lund GK, Stehning C, Schnackenburg B, Bohnen S, Adam G, et al. CMR in Patients With Severe Myocarditis: Diagnostic Value of Quantitative Tissue Markers Including Extracellular Volume Imaging. J Am Coll Cardiol Img. 2014;7:667-75.
37. Crouser ED, Ono C, Tran T, He X, Raman SV. Improved detection of cardiac sarcoidosis using magnetic resonance with myocardial T2 mapping. Am J Respir Crit Care Med. 2014;189:109-12.
38. Vermes E, Childs H, Faris P, Friedrich MG. Predictive value of CMR criteria for LV functional improvement in patients with acute myocarditis. Eur Heart J Cardiovasc Imaging. 2014;15:1140-4.
39. Mayr A, Schanen P, Loewen A, Schocke M. Cardiac magnetic resonance T2 relaxometry in acute myocarditis correlations with myocardial function and cardiac biomarkers. J Cardiovasc Magn Reson. 2015;17:P302.
40. Cooper LT, Baughman KL, Feldman AM, Frustaci A, Jessup M, Kuhl U, et al. The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology. Eur Heart J. 2007;28:3076-93.
41. Magnani JW, Dec GW. Myocarditis: current trends in diagnosis and treatment. Circulation. 2006;113:876-90.