Mass Spectrometry Imaging of Drug Related Crystal-Like Structures in Formalin-Fixed Frozen and Paraffin-Embedded Rabbit Kidney Tissue Sections

Journal of the American Society for Mass Spectrometry

Volumn 27, Issue 1, 2016, Pages 117-123

  Bruinen, Anne L ^a   Van Oevelen, Cateau ^b   Eijkel, Gert B ^a   Van Heerden, Marjolein ^b   Cuyckens, Filip ^b   Heeren, Ron M A ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

DESI; Imaging mass spectrometry; MALDI; Metabolites; Multimodal; SIMS

Indexed keywords

BIOLOGICAL ORGANS; BIOMOLECULES; DATA HANDLING; DESORPTION; ELECTROSPRAY IONIZATION; FORMALDEHYDE; MASS SPECTROMETRY; METABOLITES; PARAFFINS; PRINCIPAL COMPONENT ANALYSIS; SECONDARY ION MASS SPECTROMETRY; SPECTROMETRY; TOXICITY;

DESI; DESORPTION ELECTROSPRAY IONIZATION MASS SPECTROMETRIES; IMAGING MASS SPECTROMETRY; MALDI; MASS SPECTROMETRY IMAGING (MSI); MASS-SPECTROMETRY IMAGING; MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME OF FLIGHTS; MULTI-MODAL;

MOLECULAR IMAGING;

DRUG METABOLITE; FORMALDEHYDE; PARAFFIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DEMETHYLATION; HISTOPATHOLOGY; IMAGE ANALYSIS; KIDNEY PARENCHYMA; MASS SPECTROMETRY; NONHUMAN; PRECIPITATION; PRINCIPAL COMPONENT ANALYSIS; RABBIT; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; KIDNEY; MALE; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; MOLECULAR IMAGING; PROCEDURES;

ANIMALS; FORMALDEHYDE; KIDNEY; MALE; MOLECULAR IMAGING; PARAFFIN EMBEDDING; RABBITS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84951036083     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-015-1254-3     Document Type: Article

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