Renin-angiotensin-aldosterone system gender differences in an Afro-Caribbean population

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 16, Issue 3, 2015, Pages 539-546

  Cohall, Damian H ^a   Scantlebury Manning, Thea ^a   James, Stephen ^a   Hall, Kiana ^a   Ferrario, Carlos M ^b  

^a UNIVERSITY OF THE WEST INDIES   (Jamaica)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Afro Caribbean; angiotensin II; angiotensin (1 7); blood pressure; gender; Plasma renin activity

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN II; ANGIOTENSIN[1-7]; BIOLOGICAL MARKER;

ADULT; AFRICAN CARIBBEAN; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE MONITORING; BLOOD SAMPLING; FEMALE; HUMAN; MALE; PLASMA RENIN ACTIVITY; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; URINALYSIS; BLACK PERSON; BLOOD; BLOOD PRESSURE; CARIBBEAN; DEMOGRAPHY; METABOLISM; MIDDLE AGED; REGRESSION ANALYSIS; SEXUAL DEVELOPMENT; SYSTOLE; YOUNG ADULT;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ANGIOTENSIN II; BIOMARKERS; BLOOD PRESSURE; CARIBBEAN REGION; DEMOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; REGRESSION ANALYSIS; RENIN-ANGIOTENSIN SYSTEM; SEX CHARACTERISTICS; SYSTOLE; YOUNG ADULT;

EID: 84950314137     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320314523659     Document Type: Article

References (29)

1. Gorman BK, Read JG,. Gender disparities in adult health: An examination of three measures of morbidity. J Health Soc Behav 2006; 47: 95-110.
2. Mensah GA, Mokdad AH, Ford ES, et al. State of disparities in cardiovascular health in the United States. Circulation 2005; 111: 1233-1241.
3. Lane D, Beevers DG, Lip GY,. Ethnic differences in blood pressure and the prevalence of hypertension in England. J Hum Hypertens 2002; 16: 267-273.
4. Svetkey LP, McKeown SP, Wilson AF,. Heritability of salt sensitivity in Black Americans. Hypertension 2006; 28: 854-858.
5. Lane DA, Lip GYH,. Ethnic differences in hypertension and blood pressure control in the UK. QJM 2001; 94: 391-396.
6. Duffy SJ, Beigelsen ES, Eberhardt RT, et al. Low renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension 2005; 46: 707-713.
7. Keidar S, Strizevsky A, Raz A, et al. ACE2 activity is increased in monocyte-derived macrophages from prehypertensive subjects. Nephrol Dial Transplant 2007; 22: 597-601.
8. Reich HN, Oudit GY, Penninger JM, et al. Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease. Kidney Int 2008; 74: 1610-1616.
9. Sagnella GA,. Why is plasma renin activity lower in populations of African origin? J Hum Hypertens 2001; 15: 17-25.
10. Pendergrass KD, Pirro NT, Westwood BM, et al. Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats. Am J Physiol-Heart C 2008; 295: H10-H20.
11. Mullins JJ, Peters J, Ganten D,. Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene. Nature 1990; 344: 541-544.
12. Jessup JA, Wang H, Macnamara LM, et al. Estrogen therapy, independent of timing, improves cardiac structure and function in oophorectomized mRen2. Lewis rats. Menopause 2013; epub. Accessed June 15, 2013.
13. Sullivan JC,. Sex and the renin-angiotensin system: Inequality between the sexes in response to RAS stimulation and inhibition. J Physiol- Reg I 2008; 294: R1220-R1226.
14. Benn-Torres J, Bonilla C, Robbins CM, et al. Admixture and population stratification in African Caribbean populations. Ann Hum Genet 2008; 72: 90-98.
15. Reyes-Engel A, Morcillo L, Aranda FJ, et al. Influence of gender and genetic variability on plasma angiotensin peptides. J Renin Angiotensin Aldosterone Syst 2006; 7: 92-97.
16. Luque M, Martin P, Martell N, et al. Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension. J Hypertens 1996; 14: 799-805.
17. Ferrario CM, Martell N, Yunis C, et al. Characteri-zation of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects. Am J Hypertens 1998; 11: 137-146.
18. Kohara K, Tabuchi Y, Senanayake P, et al. Reassessment of plasma angiotensins measurement: Effects of protease inhibitors and sample handling procedures. Peptides 1991; 12: 1135-1141.
19. Sachdeva A, Weder AB,. Nocturnal sodium excretion, blood pressure dipping, and sodium sensitivity. Hypertension 2006; 48: 527-533.
20. Chappell MC, Yamaleyeva LM, Westwood BM,. Estrogen and salt sensitivity in the female mRen (2).Lewis rats. J Physiol-Reg I 2006; 291: R1557-R1593.
21. Lemmer B,. The importance of circadian rhythms on drug response in hypertension and coronary heart disease-from mice and man. Pharmacol Ther 2006; 111: 629-651.
22. Ferrario CM, Averill DB, Brosnihan KB, et al. Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat. Kidney Int 2002; 62: 1349-1357.
23. Ferrario CM, Smith RD, Brosnihan B, et al. Effects of omapatrilat on the renin-angiotensin system in salt-sensitive hypertension. Am J Hypertens 2002; 15: 557-564.
24. Ferrario CM, Jessup J, Gallagher PE, et al. Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Int 2005; 68: 2189-2196.
25. Ferrario CM, Varagic J,. The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function. Am J Physiol Renal Physiol 2010; 298: F1297-F1305.
26. Gallagher PE, Li P, Lenhart JR, et al. Estrogen regulation of angiotensin-converting enzyme mRNA. Hypertens 1999; 33: 323-328.
27. Brosnihan KB, Li P, Ganten D, et al. Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS. Am J Physiol 1997; 273: R1908-R1915.
28. Bhatia K, Zimmerman MA, Sullivan JC,. Sex differences in angiotensin-converting enzyme modulation of Ang (1-7) levels in normotensive WKY rats. Am J Hypertens 2013; 26: 591-598.
29. Francis J., Haddy, Paul M, et al. Role of potassium in regulating blood flow and blood pressure. Am J Physiol Regul Integr Comp Physiol 2006; 290: R546-R552.