-
1
-
-
36248987815
-
Metastatic carcinoma of the long bones
-
Riccio, A. I., Wodajo, F. M. & Malawer, M. Metastatic carcinoma of the long bones. Am. Fam. Physician 76, 1489-1494 (2007).
-
(2007)
Am. Fam. Physician
, vol.76
, pp. 1489-1494
-
-
Riccio, A.I.1
Wodajo, F.M.2
Malawer, M.3
-
2
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy, G. R. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat. Rev. Cancer 2, 584-593 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
3
-
-
19644378914
-
Mechanisms of cancer metastasis to the bone
-
Yin, J. J., Pollock, C. B. & Kelly, K. Mechanisms of cancer metastasis to the bone. Cell Res. 15, 57-62 (2005).
-
(2005)
Cell Res
, vol.15
, pp. 57-62
-
-
Yin, J.J.1
Pollock, C.B.2
Kelly, K.3
-
4
-
-
0035740253
-
Prostate carcinoma skeletal metastases: Cross-talk between tumor and bone
-
Keller, E. T. et al. Prostate carcinoma skeletal metastases: cross-talk between tumor and bone. Cancer Metastasis Rev. 20, 333-349 (2001).
-
(2001)
Cancer Metastasis Rev
, vol.20
, pp. 333-349
-
-
Keller, E.T.1
-
5
-
-
0034085989
-
Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
-
Bubendorf, L. et al. Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum. Pathol. 31, 578-583 (2000).
-
(2000)
Hum. Pathol.
, vol.31
, pp. 578-583
-
-
Bubendorf, L.1
-
6
-
-
0030749321
-
Skeletal complications of malignancy
-
Coleman, R. E. Skeletal complications of malignancy. Cancer 80, 1558-1594 (1997).
-
(1997)
Cancer
, vol.80
, pp. 1558-1594
-
-
Coleman, R.E.1
-
7
-
-
0037013260
-
Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin li-gases by all cullins
-
Furukawa, M., Ohta, T. & Xiong, Y. Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin li-gases by all cullins. J. Biol. Chem. 277, 15758-15765 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15758-15765
-
-
Furukawa, M.1
Ohta, T.2
Xiong, Y.3
-
8
-
-
33846899259
-
Investigation for bone metastasis from an unknown primary
-
Destombe, C. et al. Investigation for bone metastasis from an unknown primary. Joint Bone Spine 74, 85-89 (2007).
-
(2007)
Joint Bone Spine
, vol.74
, pp. 85-89
-
-
Destombe, C.1
-
9
-
-
33747181617
-
Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: A crossectional and longitudinal evaluation
-
Voorzanger-Rousselot, N. et al. Association of 12 serum biochemical markers of angiogenesis, tumour invasion and bone turnover with bone metastases from breast cancer: a crossectional and longitudinal evaluation. Br. J. Cancer 95, 506-514 (2006).
-
(2006)
Br. J. Cancer
, vol.95
, pp. 506-514
-
-
Voorzanger-Rousselot, N.1
-
10
-
-
80355128186
-
Value of C-telopeptide-cross-linked Type i collagen, osteocalcin, bone-specific alkaline phosphatase and procollagen Type i N-terminal propeptide in the diagnosis and prognosis of bone metastasis in patients with malignant tumors
-
Zhao, H. et al. Value of C-telopeptide-cross-linked Type I collagen, osteocalcin, bone-specific alkaline phosphatase and procollagen Type I N-terminal propeptide in the diagnosis and prognosis of bone metastasis in patients with malignant tumors. Med. Sci. Monit. 17, CR626-CR633 (2011).
-
(2011)
Med. Sci. Monit.
, vol.17
, pp. CR626-CR633
-
-
Zhao, H.1
-
11
-
-
0034660097
-
Markers of bone turnover in bone metastases
-
Fontana, A. & Delmas, P. D. Markers of bone turnover in bone metastases. Cancer 88, 2952-2960 (2000).
-
(2000)
Cancer
, vol.88
, pp. 2952-2960
-
-
Fontana, A.1
Delmas, P.D.2
-
12
-
-
0036299033
-
Osteoprotegerin secretion from prostate cancer isstimulated by cytokines, in vitro
-
Penno, H. et al. Osteoprotegerin secretion from prostate cancer isstimulated by cytokines, in vitro. Biochem. Biophys. Res. Commun. 293, 451-455 (2002).
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 451-455
-
-
Penno, H.1
-
13
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet, W. S. et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89, 309-319 (1997).
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
-
14
-
-
77957661914
-
Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of non-randomized studies in metaanalyses
-
Stang, A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of non-randomized studies in metaanalyses. Eur. J. Epidemiol. 25, 603-605 (2010).
-
(2010)
Eur. J. Epidemiol.
, vol.25
, pp. 603-605
-
-
Stang, A.1
-
15
-
-
49649128846
-
Serum osteoprotegerin as a novel marker of bone metastasis in prostate cancer
-
Chen, H. X. et al. Serum osteoprotegerin as a novel marker of bone metastasis in prostate cancer. Chin. J. Surg. 45, 412-414 (2007).
-
(2007)
Chin. J. Surg.
, vol.45
, pp. 412-414
-
-
Chen, H.X.1
-
16
-
-
56149084790
-
Osteoclasts are active in bone forming metastases of prostate cancer patients
-
Roato, I. et al. Osteoclasts are active in bone forming metastases of prostate cancer patients. Plos One 3, e3627 (2008).
-
(2008)
Plos One
, vol.3
, pp. e3627
-
-
Roato, I.1
-
17
-
-
67650067152
-
The clinical significance of serum markers of bone turnover in NSCLC patients: Surveillance, management and prognostic implications
-
Terpos, E. et al. The clinical significance of serum markers of bone turnover in NSCLC patients: surveillance, management and prognostic implications. Anticancer Res. 29, 1651-1658 (2009).
-
(2009)
Anticancer Res
, vol.29
, pp. 1651-1658
-
-
Terpos, E.1
-
18
-
-
84950283870
-
The clinical value of serum osteoprotegerin level in the diagnosis of lung cancer
-
Yin, J. L. & Chen, X. Y. The clinical value of serum osteoprotegerin level in the diagnosis of lung cancer. Exp. Lab. Med. 27, 7-9 (2009).
-
(2009)
Exp. Lab. Med.
, vol.27
, pp. 7-9
-
-
Yin, J.L.1
Chen, X.Y.2
-
19
-
-
84950236998
-
Clinical value of measuring serum osteoprotegerin in patients with prostate cancer
-
Zhao, X. Z. et al. Clinical value of measuring serum osteoprotegerin in patients with prostate cancer. Clinical Medicine of China 26, 1242-1243 (2010).
-
(2010)
Clinical Medicine of China
, vol.26
, pp. 1242-1243
-
-
Zhao, X.Z.1
-
20
-
-
77956479847
-
Serum bone turnover markers may be involved in the metastatic potential of lung cancer patients
-
Karapanagiotou, E. M. et al. Serum bone turnover markers may be involved in the metastatic potential of lung cancer patients. Med. Oncol. 27, 332-338 (2010).
-
(2010)
Med. Oncol.
, vol.27
, pp. 332-338
-
-
Karapanagiotou, E.M.1
-
21
-
-
80052773257
-
Significance of serum osteoprotegerin and receptor activator of nuclear factor B ligand in Japanese prostate cancer patients with bone metastasis
-
Kamiya, N. et al. Significance of serum osteoprotegerin and receptor activator of nuclear factor B ligand in Japanese prostate cancer patients with bone metastasis. Int. J. Clin. Oncol. 16, 366-372 (2011).
-
(2011)
Int. J. Clin. Oncol.
, vol.16
, pp. 366-372
-
-
Kamiya, N.1
-
22
-
-
84950261930
-
The clinical assessment on lesions shown 99mTc-MDP whole body bone scan and determination of serum levels of OPG BSP and TRACP-5b in lung cancerpatients with bone metastasis
-
Zhu, B., Shao, K. J., Yuan, H. & Xu, Y. F. The clinical assessment on lesions shown 99mTc-MDP whole body bone scan and determination of serum levels of OPG, BSP and TRACP-5b in lung cancerpatients with bone metastasis. J. Radioimmunology. 26, 545-547 (2013).
-
(2013)
J. Radioimmunology.
, vol.26
, pp. 545-547
-
-
Zhu, B.1
Shao, K.J.2
Yuan, H.3
Xu, Y.F.4
-
23
-
-
84950283053
-
And clinical significance of serum OPG, BMP-7 and PSA in patients with prostatic cancer
-
Bu, J. S. Changes and clinical significance of serum OPG, BMP-7 and PSA in patients with prostatic cancer. Chinese Journal of Health Laboratory Technology 23, 168-170 (2013).
-
(2013)
Chinese Journal of Health Laboratory Technology
, vol.23
, pp. 168-170
-
-
Bu, J.S.1
Changes2
-
24
-
-
84979679617
-
The diagnostic value of serum osteoclast differentiation factor and inhibitory factor in bone metastasis of lung cancer
-
Li, L., Tan, B. Y., Liu, Z. W., Chen, M. & Zhang, Y. The diagnostic value of serum osteoclast differentiation factor and inhibitory factor in bone metastasis of lung cancer. Int. J. Lab. Med. 34, 1930-1934 (2013).
-
(2013)
Int. J. Lab. Med.
, vol.34
, pp. 1930-1934
-
-
Li, L.1
Tan, B.Y.2
Liu, Z.W.3
Chen, M.4
Zhang, Y.5
-
25
-
-
84950263063
-
Significance of ODF and OCIF in diagnosis of prostate cancer bone metastases
-
Tan, Y. C. Significance of ODF and OCIF in diagnosis of prostate cancer bone metastases. China Journal of Modern Medicine 24, 37-40 (2014)
-
(2014)
China Journal of Modern Medicine
, vol.24
, pp. 37-40
-
-
Tan, Y.C.1
-
26
-
-
0031747833
-
Prostate-specific antigen in the cerebrospinal fluid leads to diagnosis of solitary cauda equina metastasis: A unique case report and review of the literature
-
Schaller, B. et al. Prostate-specific antigen in the cerebrospinal fluid leads to diagnosis of solitary cauda equina metastasis: a unique case report and review of the literature. Br. J. Cancer 77, 2386-2389 (1998).
-
(1998)
Br. J. Cancer
, vol.77
, pp. 2386-2389
-
-
Schaller, B.1
-
27
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast
-
Paget, S. The distribution of secondary growths in cancer of the breast. Cancer Metastasis Rev. 8, 98-101 (1989).
-
(1989)
Cancer Metastasis Rev
, vol.8
, pp. 98-101
-
-
Paget, S.1
-
28
-
-
0030879065
-
Mechanisms of bone metastasis
-
Gregory, R. & Mundy, M. D. Mechanisms of bone metastasis. Cancer 80, 1546-1556 (1997).
-
(1997)
Cancer
, vol.80
, pp. 1546-1556
-
-
Gregory, R.1
Mundy, M.D.2
-
29
-
-
4043138669
-
Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAILinduced apoptosis
-
Neville-Webbe, H. L. et al. Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAILinduced apoptosis. Breast Cancer Res. Treat. 86, 269-279 (2004).
-
(2004)
Breast Cancer Res. Treat.
, vol.86
, pp. 269-279
-
-
Neville-Webbe, H.L.1
-
30
-
-
3242781731
-
Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
-
Hofbauer, L. C. & Schoppet, M. Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 292, 490-495 (2004).
-
(2004)
JAMA
, vol.292
, pp. 490-495
-
-
Hofbauer, L.C.1
Schoppet, M.2
-
31
-
-
0034673525
-
Cancer cells responsible for humoral hypercalcaemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation
-
Nagai, M., Kyakumoto, S. & Sato, N. Cancer cells responsible for humoral hypercalcaemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation. Biochem. Biophys. Res. Commun. 269, 532-536 (2000).
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.269
, pp. 532-536
-
-
Nagai, M.1
Kyakumoto, S.2
Sato, N.3
-
32
-
-
0036845366
-
Tumor cells produce receptor activator of NF-kB ligand (RANKL) in skeletal metastases
-
Huang, L., Cheng, Y. Y., Chow, L. T., Kumta, S. M. & Zheng, M. H. Tumor cells produce receptor activator of NF-kB ligand (RANKL) in skeletal metastases. J. Clin. Pathol. 55, 877-878 (2002).
-
(2002)
J. Clin. Pathol.
, vol.55
, pp. 877-878
-
-
Huang, L.1
Cheng, Y.Y.2
Chow, L.T.3
Kumta, S.M.4
Zheng, M.H.5
-
33
-
-
0034771689
-
Osteoprotegerin in serum as a novel marker of bone metastatic spread in prostate cancer
-
Jung, K. et al. Osteoprotegerin in serum as a novel marker of bone metastatic spread in prostate cancer. Clin. Chem. 47, 2061-2063 (2001).
-
(2001)
Clin. Chem.
, vol.47
, pp. 2061-2063
-
-
Jung, K.1
-
34
-
-
2342646240
-
The receptor activity modifying protein family of G protein coupled receptor accessory proteins
-
Udawela, M., Hay, D. L. & Sexton, P. M. The receptor activity modifying protein family of G protein coupled receptor accessory proteins. Semin. Cell Dev. Biol. 15, 299-308 (2004).
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 299-308
-
-
Udawela, M.1
Hay, D.L.2
Sexton, P.M.3
-
35
-
-
9244252016
-
The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodelling
-
Theoleyre, S. et al. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodelling. Cytokine Growth Factor Rev. 15, 457-475 (2004).
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 457-475
-
-
Theoleyre, S.1
-
36
-
-
33644789211
-
Role of osteoprotegerin (OPG) in cancer
-
Holen, I. & Shipman, C. M. Role of osteoprotegerin (OPG) in cancer. Clin. Sci. 110, 279-291 (2006).
-
(2006)
Clin. Sci.
, vol.110
, pp. 279-291
-
-
Holen, I.1
Shipman, C.M.2
-
37
-
-
0142182080
-
Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis
-
Grimaud, E. et al. Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis. Am. J. Pathol. 163, 2021-2031 (2003).
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2021-2031
-
-
Grimaud, E.1
-
38
-
-
0043245842
-
Soluble receptor activator of nuclear factor kappa-B ligand-osteoprotegerin ratio predicts survival in multiple myeloma: Proposal for a novel prognostic index
-
Terpos, E. et al. Soluble receptor activator of nuclear factor kappa-B ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index. Blood 102, 1064-1069 (2003).
-
(2003)
Blood
, vol.102
, pp. 1064-1069
-
-
Terpos, E.1
-
39
-
-
0042914647
-
Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial-The Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
-
Rosen, L. S. et al. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial-the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J. Clin. Oncol. 21, 3150-3157 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3150-3157
-
-
Rosen, L.S.1
-
40
-
-
43049109229
-
Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy
-
Russell, R. G., Watts, N. B., Ebetino, F. H. & Rogers, M. J. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos. Int. 19, 733-759 (2008).
-
(2008)
Osteoporos. Int.
, vol.19
, pp. 733-759
-
-
Russell, R.G.1
Watts, N.B.2
Ebetino, F.H.3
Rogers, M.J.4
-
41
-
-
79958716455
-
Biochemical and molecular mechanisms of action of bisphosphonates
-
Rogers, M. J., Crockett, J. C., Coxon, F. P. & Mönkkönen, J. Biochemical and molecular mechanisms of action of bisphosphonates. Bone 49, 34-41 (2010).
-
(2010)
Bone
, vol.49
, pp. 34-41
-
-
Rogers, M.J.1
Crockett, J.C.2
Coxon, F.P.3
Mönkkönen, J.4
-
42
-
-
84881024325
-
Efficacy and safety of denosumab versus zoledronic acid in patients with bone metastases: A systematic review and meta-analysis
-
Sun, L. & Yu, S. Efficacy and safety of denosumab versus zoledronic acid in patients with bone metastases: a systematic review and meta-analysis. Am. J. Clin. Oncol. 36, 399-403 (2013).
-
(2013)
Am. J. Clin. Oncol.
, vol.36
, pp. 399-403
-
-
Sun, L.1
Yu, S.2
-
43
-
-
84895880108
-
Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: An analysis of data from patients with solid tumors
-
Henry, D. et al. Delaying skeletal-related events in a randomized phase 3 study of denosumab versus zoledronic acid in patients with advanced cancer: an analysis of data from patients with solid tumors. Support Care Cancer 22, 679-87 (2014).
-
(2014)
Support Care Cancer
, vol.22
, pp. 679-687
-
-
Henry, D.1
-
44
-
-
0035021176
-
Osteoprotegerin inhibits prostate cancer induced osteoclastogenesis and prevents tumor growth in the bone
-
Zhang, J. et al. Osteoprotegerin inhibits prostate cancer induced osteoclastogenesis and prevents tumor growth in the bone. J. Clin. Invest. 107, 1235-1244 (2001).
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1235-1244
-
-
Zhang, J.1
-
45
-
-
51049121618
-
RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis
-
Miller, R. E. et al. RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis. Mol. Cancer Ther. 7, 2160-2169 (2008).
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2160-2169
-
-
Miller, R.E.1
-
46
-
-
0032578781
-
Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone-resorbing activity of isolated mature osteoclasts
-
Hakeda, Y. et al. Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone-resorbing activity of isolated mature osteoclasts. Biochem. Biophys. Res. Commun. 251, 796-801 (1998).
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.251
, pp. 796-801
-
-
Hakeda, Y.1
-
47
-
-
0037302045
-
Mechanisms of tumor metastasis to the bone: Challenges and opportunities
-
Reddi, A. H., Roodman, D., Freeman, C. & Mohla, S. Mechanisms of tumor metastasis to the bone: challenges and opportunities. J. Bone Miner. Res. 18, 190-194 (2003).
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 190-194
-
-
Reddi, A.H.1
Roodman, D.2
Freeman, C.3
Mohla, S.4
-
48
-
-
0032544518
-
Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast
-
Akatsu, T. et al. Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast. Biochem. Biophys. Res. Commun. 250, 229-234 (1998).
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.250
, pp. 229-234
-
-
Akatsu, T.1
-
49
-
-
0037086077
-
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells
-
Holen, I., Crouche, P. I., Hamdy, F. C. & Eaton, C. L. Osteoprotegerin (OPG) is a survival factor for human prostate cancer cells. Cancer Res. 62, 1619-1623 (2002).
-
(2002)
Cancer Res
, vol.62
, pp. 1619-1623
-
-
Holen, I.1
Crouche, P.I.2
Hamdy, F.C.3
Eaton, C.L.4
-
50
-
-
13444294592
-
Human bone marrow stromal cells protect prostate cancer cells from TRAIL-induced apoptosis
-
Nyambo, R. et al. Human bone marrow stromal cells protect prostate cancer cells from TRAIL-induced apoptosis. J. Bone Miner. Res. 191, 712-1721 (2004).
-
(2004)
J. Bone Miner. Res.
, vol.191
, pp. 712-1721
-
-
Nyambo, R.1
-
51
-
-
0346158479
-
Expression of osteoprotegerin and RANK ligand in breast cancer bone metastasis
-
Park, H. R. et al. Expression of osteoprotegerin and RANK ligand in breast cancer bone metastasis. J. Korean Med. Sci. 18, 541-546 (2003).
-
(2003)
J. Korean Med. Sci.
, vol.18
, pp. 541-546
-
-
Park, H.R.1
-
52
-
-
24644435593
-
Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo-A role in tumour cell survival
-
Holen, I. et al. Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo-a role in tumour cell survival Breast Cancer Res. Treat. 92, 207-215 (2005).
-
(2005)
Breast Cancer Res. Treat
, vol.92
, pp. 207-215
-
-
Holen, I.1
-
53
-
-
33645221176
-
Osteoprotegerin (OPG)-A potential new role inthe regulation of endothelial cell phenotype and tumour angiogenesis Int
-
Cross, S. S. et al. Osteoprotegerin (OPG)-a potential new role inthe regulation of endothelial cell phenotype and tumour angiogenesis Int. J. Cancer 118, 1901-1908 (2006).
-
(2006)
J. Cancer
, vol.118
, pp. 1901-1908
-
-
Cross, S.S.1
|