Prevalence and genetic diversity of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in nursing homes in Bavaria, Germany

Veterinary Microbiology

Volumn 200, Issue , 2017, Pages 138-141

  Valenza, Giuseppe ^a   Nickel, Silke ^a   Pfeifer, Yvonne ^b   Pietsch, Michael ^b   Voigtländer, Elzbieta ^c   Lehner Reindl, Verena ^a   Höller, Christiane ^d  

^a Bavarian Health and Food Safety Authority   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c Bavarian Health and Food Safety Authority   (Germany)

^d Bavarian Health and Food Safety Authority   (Germany)

Author keywords

Antibiotic resistance; Colonisation; CTX M 15; ST131

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 1; BETA LACTAMASE CTX M 14; BETA LACTAMASE CTX M 15; BETA LACTAMASE CTX M 27; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFPODOXIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; ERTAPENEM; FOSFOMYCIN; GENTAMICIN; IMIPENEM; NALIDIXIC ACID; TETRACYCLINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BETA LACTAMASE; BETA-LACTAMASE CTX-M-15;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL TRANSMISSION; BACTERIUM DETECTION; BACTERIUM ISOLATE; CLONE; COMPARATIVE STUDY; CONTROLLED STUDY; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ESCHERICHIA COLI; FEMALE; GENETIC VARIABILITY; GERMANY; HUMAN; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; NONHUMAN; NURSING HOME; NURSING HOME PATIENT; POLYMERASE CHAIN REACTION; PREVALENCE; PULSED FIELD GEL ELECTROPHORESIS; ANIMAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ENZYMOLOGY; ESCHERICHIA COLI; GENETIC VARIATION; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; RISK FACTOR; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CIPROFLOXACIN; DRUG RESISTANCE, BACTERIAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; FEMALE; GENETIC VARIATION; GERMANY; HUMANS; MALE; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; MOLECULAR TYPING; NURSING HOMES; PREVALENCE; RISK FACTORS;

EID: 84950284893     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2015.10.008     Document Type: Article

References (18)

1. Arvand, M., Moser, V., Pfeifer, Y., Prevalence of extended-spectrum beta-lactamase-producing E. coli and spread of the epidemic clonal lineage ST131 in nursing homes in Hesse, Germany. J. Antimicrob. Chemother., 6, 2013, 10.1093/jac/dkt226.
2. Blanco, M., Alonso, M.P., Nicolas-Chanoine, M.H., Dahbi, G., Mora, A., Blanco, J.E., López, C., Cortés, P., Llagostera, M., Leflon-Guibout, V., Puentes, B., Mamani, R., Herrera, A., Coira, M.A., García-Garrote, F., Pita, J.M., Blanco, J., Molecular epidemiology of E. coli producing extended-spectrum {beta}-lactamases in Lugo (Spain): dissemination of clone O25b:H4-ST131 producing CTX-M-15. J. Antimicrob. Chemother. 63 (2009), 1135–1141.
3. Clermont, O., Bonacorsi, S., Bingen, E., Rapid and simple determination of the E. coli phylogenetic group. Appl. Environ. Microbiol. 66 (2000), 4555–4558.
4. Clermont, O., Lavollay, M., Vimont, S., Deschamps, C., Forestier, C., Branger, C., Denamur, E., Arlet, G., The CTX-M-15-producing E. coli diffusing clone belongs to a highly virulent B2 phylogenetic subgroup. J. Antimicrob. Chemother. 61 (2008), 1024–1028.
5. Clinical, Laboratory Standards Institute, Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement. CLSI Document M100-S19. 2010, Clinical and Laboratory Standards Institute, Wayne, PA, USA.
6. Eller, C., Simon, S., Miller, T., Frick, J.S., Prager, R., Rabsch, W., Guerra, B., Werner, G., Pfeifer, Y., Presence of ß-lactamases in extended spectrum-cephalosporin-resistant Salmonella enterica of 30 different serovars in Germany 2005-11. J. Antimicrob. Chemother. 68 (2013), 1978–1981.
7. Geser, N., Stephan, R., Korczak, B.M., Beutin, L., Hächler, H., Molecular identification of extended-spectrum-ß-lactamase genes from Enterobacteriaceae isolated from healthy human carriers in Switzerland. Antimicrob. Agents Chemother. 56 (2012), 1609–1612.
8. Gröbner, S., Linke, D., Schütz, W., Fladerer, C., Madlung, J., Autenrieth, I.B., Witte, W., Pfeifer, Y., Emergence of carbapenem-non-susceptible extended-spectrum beta-lactamase producing Klebsiella pneumoniae isolates at the university hospital of Tubingen, Germany. J. Med. Microbiol. 58 (2009), 912–922.
9. Gruber, I., Heudorf, U., Werner, G., Pfeifer, Y., Imirzalioglu, C., Ackermann, H., Brandt, C., Besier, S., Wichelhaus, T.A., Multidrug-resistant bacteria in geriatric clinics, nursing homes, and ambulant care-prevalence and risk factors. Int. J. Med. Microbiol. 303 (2013), 405–409.
10. Johnson, J.R., Johnston, B., Clabots, C., Kuskowski, M.A., Castanheira, M., E. coli sequence type ST131 as the major cause of serious multidrug-resistant E. coli infections in the United States. Clin. Infect. Dis. 51 (2010), 286–294.
11. Kresken, M., Pfeifer, Y., Hafner, D., Wresch, R., Körber-Irrgang, B., Working Party ‘Antimicrobial Resistance’ of the Paul-Ehrlich-Society for Chemotherapy,. Occurrence of multidrug resistance to oral antibiotics among E. coli urine isolates from outpatient departments in Germany: extended-spectrum β-lactamases and the role of fosfomycin. Int. J. Antimicrob. Agents 44 (2014), 295–300.
12. Lübbert, C., Straube, L., Stein, C., Makarewicz, O., Schubert, S., Mössner, J., Pletz, M.W., Rodloff, A.C., Colonization with extended-spectrum beta-lactamase-producing and carbapenemase-producing Enterobacteriaceae in international travelers returning to Germany. Int. J. Med. Microbiol. 305 (2015), 148–156.
13. Mathers, A.J., Peirano, G., Pitout, J.D., E. coli ST131: the quintessential example of an international multiresistant high-risk clone. Adv. Appl. Microbiol. 90 (2015), 109–154.
14. Nicolas-Chanoine, M.H., Blanco, J., Leflon-Guibout, V., Demarty, R., Alonso, M.P., Caniça, M.M., Park, Y.J., Lavigne, J.P., Pitout, J., Johnson, J.R., Intercontinental emergence of E. coli clone O25:H4-ST131 producing CTX-M-15. J. Antimicrob. Chemother. 61 (2008), 273–281.
15. Nicolas-Chanoine, M.H., Gruson, C., Bialek-Davenet, S., Bertrand, X., Thomas-Jean, F., Bert, F., Moyat, M., Meiller, E., Marcon, E., Danchin, N., Noussair, L., Moreau, R., Leflon-Guibout, V., 10-Fold increase (2006–11) in the rate of healthy subjects with extended-spectrum-ß-lactamase-producing E. coli faecal carriage in a Parisian check-up centre. J. Antimicrob. Chemother. 68 (2013), 562–568.
16. Ruscher, C., Pfeifer, Y., Layer, F., Schaumann, R., Levin, K., Mielke, M., Inguinal skin colonization with multidrug-resistant bacteria among residents of elderly care facilities: frequency, persistence, molecular analysis and clinical impact. Int. J. Med. Microbiol. 304 (2014), 1123–1134.
17. Tenover, F.C., Arbeit, R.D., Goering, R.V., Mickelsen, P.A., Murray, B.E., Persing, D.H., Swaminathan, B., Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 33 (1995), 2233–2239.
18. Valenza, G., Nickel, S., Pfeifer, Y., Eller, C., Krupa, E., Lehner-Reindl, V., Höller, C., Extended-spectrum-ö-lactamase-producing E. coli as intestinal colonizers in the German community. Antimicrob. Agents Chemother. 58 (2014), 1228–1230.