Effectiveness of ring vaccination as control strategy for Ebola virus disease

Emerging Infectious Diseases

Volumn 22, Issue 1, 2016, Pages 105-108

  Kucharski, Adam J ^a   Eggo, Rosalind M ^a   Watson, Conall H ^a   Camacho, Anton ^a   Funk, Sebastian ^a   Edmunds, W John ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EBOLA VACCINE;

ARTICLE; DRUG EFFICACY; EBOLA HEMORRHAGIC FEVER; GEOGRAPHIC DISTRIBUTION; HUMAN; NONHUMAN; RING VACCINATION; VACCINATION; VIRUS ISOLATION; VIRUS TRANSMISSION; AFRICA; DISEASE OUTBREAKS; EBOLAVIRUS; EPIDEMIC; HEMORRHAGIC FEVER, EBOLA; IMMUNOLOGY; PROCEDURES; THEORETICAL MODEL;

AFRICA, WESTERN; DISEASE OUTBREAKS; EBOLAVIRUS; EPIDEMICS; HEMORRHAGIC FEVER, EBOLA; HUMANS; MODELS, THEORETICAL; VACCINATION;

EID: 84950259396     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid2201.151410     Document Type: Article

References (14)

1. Wellcome Trust, Center for Infectious Disease Research and Policy. Recommendations for accelerating the development of Ebola vaccines [cited 2015 Oct 20]. http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtp058693.pdf
2. Ebola ça Suffit Ring Vaccination Trial Consortium. The ring vaccination trial: a novel cluster randomised controlled trial design to evaluate vaccine efficacy and effectiveness during outbreaks, with special reference to Ebola. BMJ. 2015;351:h3740.
3. Henao-Restrepo AM, Longini I Jr, Egger M, Dean NE, Edmunds WJ, Camacho A, et al. Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet. 2015;386:857–66.
4. Fenner F, Henderson DA, Arita I, Jezek Z, Ladnyi ID. Smallpox and its eradication. Geneva: World Health Organization; 1988.
5. Wells C, Yamin D, Ndeffo-Mbah ML, Wenzel N, Gaffney SG, Townsend JP, et al. Harnessing case isolation and ring vaccination to control Ebola. PLoS Negl Trop Dis. 2015;9:e0003794. http://dx.doi.org/10.1371/journal.pntd.0003794
6. Althaus CL. Ebola superspreading. Lancet Infect Dis. 2015;15:507–8. http://dx.doi.org/10.1016/S1473-3099(15)70135-0
7. Faye O, Böelle PY, Heleze E, Faye O, Loucoubar C, Magassouba N, et al. Chains of transmission and control of Ebola virus disease in Conakry, Guinea, in 2014: an observational study. Lancet Infect Dis. 2015;15:320–6. http://dx.doi.org/10.1016/S1473-3099(14)71075-8
8. Kretzschmar M, Van den Hof S, Wallinga J, Van Wijngaarden J. Ring vaccination and smallpox control. Emerg Infect Dis. 2004;10:832–41. http://dx.doi.org/10.3201/eid1005.030419
9. Lloyd-Smith JO, Schreiber SJ, Kopp PE, Getz WM. Superspreading and the effect of individual variation on disease emergence. Nature. 2005;438:355–9. http://dx.doi.org/10.1038/nature04153
10. WHO Ebola Response Team. Ebola virus disease in West Africa— the first 9 months of the epidemic and forward projections. N Engl J Med. 2014;371:1481–95. http://dx.doi.org/10.1056/NEJMoa1411100
11. Centre for the Mathematical Modelling of Infectious Diseases. Visualisation and projections of the Ebola outbreak in West Africa [cited 2015 Oct 20]. http://cmmid.lshtm.ac.uk/ebola/
12. Nielsen CF, Kidd S, Sillah AR, Davis E, Mermin J, Kilmarx PH. Improving burial practices and cemetery management during an Ebola virus disease epidemic—Sierra Leone, 2014. MMWR Morb Mortal Wkly Rep. 2015;64:20–7.
13. Camacho A, Kucharski AJ, Funk S, Breman J, Piot P, Edmunds WJ. Potential for large outbreaks of Ebola virus disease. Epidemics. 2014;9:70–8. http://dx.doi.org/10.1016/j.epidem.2014.09.003
14. Heymann DL. Ebola: learn from the past. Nature. 2014;514:299–300. http://dx.doi.org/10.1038/514299a