A handheld laser-induced fluorescence detector for multiple applications

Talanta

Volumn 150, Issue , 2016, Pages 135-141

  Fang, Xiao Xia ^a   Li, Han Yang ^a   Fang, Pan ^a   Pan, Jian Zhang ^a   Fang, Qun ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Abbreviations LIF laser induced fluorescence; ADC analog to digital converter; APD avalanche photodiode; CE capillary electrophoresis; FITC fluorescein isothiocyanate; FSC forward scattered; LED light emitting diode; NA numerical aperture; PD photodiode; POCT point of care testing; SNR signal to noise ratio

Indexed keywords

ANALOG TO DIGITAL CONVERSION; AVALANCHE DIODES; BANDPASS FILTERS; CAPILLARY ELECTROPHORESIS; DIODES; DROP FORMATION; FLUORESCENCE; FORWARD SCATTERING; LASER EXCITATION; LASER OPTICS; LASER PRODUCED PLASMAS; LENSES; LIGHT; PHOTODIODES; PHOTOMULTIPLIERS; SIGNAL TO NOISE RATIO; SPEED CONTROL;

ANALOG TO DIGITAL CONVERTERS; FLUORESCEIN ISOTHIOCYANATE; FSC FORWARD SCATTERED; LED LIGHTS; LIF LASER; NUMERICAL APERTURE; POINT-OF-CARE TESTING; SNR SIGNAL TO NOISE RATIO;

LASER MIRRORS;

EID: 84950252116     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2015.12.018     Document Type: Article

References (34)

1. J.M. Cunliffe, R.K. Sunahara, and R.T. Kennedy Detection of g protein coupled receptor mediated adenylyl cyclase activity by capillary electrophoresis using fluorescently labeled ATP Anal. Chem. 79 2007 7534 7539 10.1021/ac071203
2. Z. Zhang, S. Krylov, E.A. Arriaga, R. Polakowski, and N.J. Dovichi One-dimensional protein analysis of an HT29 human colon adenocarcinoma cell Anal. Chem. 72 2000 318 322 10.1021/ac990694y
3. D.J. Harrison, A. Manz, Z.H. Fan, H. Luedi, and H.M. Widmer Capillary electrophoresis and sample injection systems integrated on a planar glass chip Anal. Chem. 64 1992 1926 1932 10.1021/ac00041a030
4. J.R. Scherer, P. Liu, and R.A. Mathies Design and operation of a portable scanner for high performance microchip capillary array electrophoresis Rev. Sci. Instrum. 81 2010 11310510.1063/1.3502457
5. P. Chen, D. Pan, and Z. Mao Development of a portable laser-induced fluorescence system used for in situ measurements of dissolved organic matter Opt. Laser Technol. 64 2014 213 219 10.1016/j.optlastec.2014.05.021
6. M. Benhabib, T.N. Chiesl, A.M. Stockton, J.R. Scherer, and R.A. Mathies Multichannel capillary electrophoresis microdevice and instrumentation for in situ planetary analysis of organic molecules and biomarkers Anal. Chem. 82 2010 2372 2379 10.1021/ac9025994
7. A.J. Tudos, G.J. Besselink, and R.B. Schasfoort Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry Lab Chip 1 2001 83 95 10.1039/b106958f
8. A.M. Skelley, J.R. Scherer, A.D. Aubrey, W.H. Grover, R.H.C. Ivester, P. Ehrenfreund, F.J. Grunthaner, J.L. Bada, and R.A. Mathies Development and evaluation of a microdevice for amino acid biomarker detection and analysis on Mars Proc. Natl. Acad. Sci. USA 102 2005 1041 1046 10.1073/pnas.0406798102
9. M.A. Seia, S.V. Pereira, C.A. Fontán, I.E. De Vito, G.A. Messina, and J. Raba Laser-induced fluorescence integrated in a microfluidic immunosensor for quantification of human serum IgG antibodies to Helicobacter pylori Sens. Actuators B Chem. 168 2012 297 302 10.1016/j.snb.2012.04.026
10. R.J. Meagher, A.V. Hatch, R.F. Renzi, and A.K. Singh An integrated microfluidic platform for sensitive and rapid detection of biological toxins Lab Chip 8 2008 2046 2053 10.1039/b815152k
11. L. Riddick, and W.C. Brumley Capillary electrophoresis with laser-induced fluorescence P. Schmitt-Kopplin, Capillary Electrophoresis - Methods and Protocols 2008 Humana Press Totowa, USA 119 134 10.1007/978-1-59745-376-9-6
12. E.H. Turner, K. Lauterbach, H.R. Pugsley, V.R. Palmer, and N.J. Dovichi Detection of green fluorescent protein in a single bacterium by capillary electrophoresis with laser-induced fluorescence Anal. Chem. 79 2007 778 781 10.1021/ac061778r
13. A.B. Anderson, C.M. Ciriacks, K.M. Fuller, and E.A. Arriaga Distribution of zeptomole-abundant doxorubicin metabolites in subcellular fractions by capillary electrophoresis with laser-induced fluorescence detection Anal. Chem. 75 2003 8 15 10.1021/ac020426r
14. R.F. Renzi, J. Stamps, B.A. Horn, S. Ferko, V.A. Vandernoot, J.A.A. West, and et al. Hand-held microanalytical instrument for chip-based electrophoretic separations of proteins Anal. Chem. 77 2005 435 441 10.1021/ac049214f
15. L. Novak, P. Neuzil, J. Pipper, Y. Zhang, and S. Lee An integrated fluorescence detection system for lab-on-a-chip applications Lab Chip 7 2007 27 29 10.1039/b611745g
16. S.-L. Wang, X.-J. Huang, Z.-L. Fang, and P.K. Dasgupta A miniaturized liquid core waveguide-capillary electrophoresis system with flow injection sample introduction and fluorometric detection using light-emitting diodes Anal. Chem. 73 2001 4545 4549 10.1021/ac010341a
17. F.-B. Yang, J.-Z. Pan, T. Zhang, and Q. Fang A low-cost light-emitting diode induced fluorescence detector for capillary electrophoresis based on an orthogonal optical arrangement Talanta 78 2009 1155 1158 10.1016/j.talanta.2009.01.033
18. J. Wu, X. Liu, L. Wang, L. Dong, and Q. Pu An economical fluorescence detector for lab-on-a-chip devices with a light emitting photodiode and a low-cost avalanche photodiode Analyst 137 2012 519 525 10.1039/c1an15867h
19. T. Zhang, Q. Fang, W.-B. Du, and J.-L. Fu Microfluidic picoliter-scale translational spontaneous sample introduction for high-speed capillary electrophoresis Anal. Chem. 81 2009 3693 3698 10.1021/ac900573x
20. W.-B. Du, Q. Fang, and Z.-L. Fang Microfluidic sequential injection analysis in a short capillary Anal. Chem. 78 2006 6404 6410 10.1021/ac060714d
21. Q. Fang, G.-M. Xu, and Z.-L. Fang A high-throughput continuous sample introduction interface for microfluidic chip-based capillary electrophoresis systems Anal. Chem. 74 2002 1223 1231 10.1021/ac010925c
22. B.C. Giordano, L. Jin, A.J. Couch, J.P. Ferrance, and J.P. Landers Microchip laser-induced fluorescence detection of proteins at submicrogram per milliliter levels mediated by dynamic labeling under pseudonative conditions Anal. Chem. 76 2004 4705 4714 10.1021/ac030349f
23. Z.D. Sandlin, M. Shou, J.G. Shackman, and R.T. Kennedy Microfluidic electrophoresis chip coupled to microdialysis for in vivo monitoring of amino acid neurotransmitters Anal. Chem. 77 2005 7702 7708 10.1021/ac051044z
24. J.-H. Qin, N.-N. Ye, L.-F. Yu, D.-Y. Liu, Y.-S. Fung, W. Wang, and et al. Simultaneous and ultrarapid determination of reactive oxygen species and reduced glutathione in apoptotic leukemia cells by microchip electrophoresis Electrophoresis 26 2005 1155 1162 10.1002/elps.200410136
25. K. Sathiyamoorthy, V.K. Mohankumar, and V.M. Murukeshan Real time monitoring of fluorescent particles in micro-channels by high resolution dual modality probe imaging Opt. Photon. J. 1 2011 197 203 10.4236/opj.2011.14031
26. Q. Li, T. Zhang, Y. Zhu, Y.-Q. Cheng, Q.-H. Lin, and Q. Fang Automated high-speed CE system for multiple samples Electrophoresis 34 2013 557 561 10.1002/elps.201200401
27. J.-L. Fu, Q. Fang, T. Zhang, X.-H. Jin, and Z.-L. Fang Laser-induced fluorescence detection system for microfluidic chips based on an orthogonal optical arrangement Anal. Chem. 78 2006 3827 3834 10.1021/ac060153q
28. Y. Zhu, N.-N. Chen, Q. Li, and Q. Fang Improving the sensitivity of confocal laser induced fluorescence detection to the sub-picomolar scale for round capillaries by laterally shifting the laser focus point Analyst 138 2013 4642 4648 10.1039/c3an00345k
29. A.M. Skelley, and R.A. Mathies Chiral separation of fluorescamine-labeled amino acids using microfabricated capillary electrophoresis devices for extraterrestrial exploration J. Chromatogr. A 1021 2003 191 199 10.1016/j.chroma.2003.08.096
30. K. Hata, Y. Kichise, T. Kaneta, and T. Imasaka Hadamard transform microchip electrophoresis combined with diode laser fluorometry Anal. Chem. 75 2003 1765 1768 10.1021/ac026330e
31. S. Götz, and U. Karst Recent developments in optical detection methods for microchip separations Anal. Bioanal. Chem. 387 2007 183 192 10.1007/s00216-006-0820-8
32. T. Kamei Miniaturized and integrated fluorescence detectors for microfluidic capillary electrophoresis devices A. Rasooly, K.E. Herold, Biosensors and Biodetection 2009 361 374 10.1007/978-1-60327-567-5-20
33. C. Wohlfarth Refractive index of water M.D. Lechner, Refractive indices of pure liquids and binary liquid mixtures 2008 Springer Berlin Heidelberg 37 41 10.1007/978-3-540-75291-2-4
34. S. Terabe, Capillary electrophoresis and microchip, in: S. Kitamori, T. Fujita, H. Hasebe (Eds.), Proceedings of Micro Total analysis systems, Tokyo, Japan, 2006, pp. 1032-1033.