-
1
-
-
78650549662
-
Preexposure chemoprophylaxis for HIV preventioninmenwhohavesex withmen
-
Grant R, Lama J, Anderson P, et al. Preexposure chemoprophylaxis for HIV preventioninmenwhohavesex withmen. NEngl JMed2010;363:2587-2599.
-
(2010)
NEngl JMed
, vol.363
, pp. 2587-2599
-
-
Grant, R.1
Lama, J.2
Anderson, P.3
-
2
-
-
84906793896
-
Uptake of preexposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: A cohort study
-
Grant R, Anderson P, McMahan V, et al. Uptake of preexposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study. Lancet 2014; 14:820-829.
-
(2014)
Lancet
, vol.14
, pp. 820-829
-
-
Grant, R.1
Anderson, P.2
McMahan, V.3
-
4
-
-
84928406861
-
Pragmatic open-label randomised trial of preexposure prophylaxis: The proud study
-
online dx doi
-
McCormack S, Dunn D, Desai, M. et al. Pragmatic open-label randomised trial of preexposure prophylaxis: The PROUD study Lancet online 2015 dx. doi.
-
(2015)
Lancet
-
-
McCormack, S.1
Dunn, D.2
Desai, M.3
-
5
-
-
84864505868
-
Antiretroviral prophylaxis for HIV prevention in heterosexual men and women
-
Baeten J, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med 2012; 367:399-410.
-
(2012)
N Engl J Med
, vol.367
, pp. 399-410
-
-
Baeten, J.1
Donnell, D.2
Ndase, P.3
-
6
-
-
84886804053
-
Exploring concentration response in HIV preexposure prophylaxis to optimize clinical care and trial design
-
Hendrix C. Exploring concentration response in HIV preexposure prophylaxis to optimize clinical care and trial design. Cell 2013; 155:515-518.
-
(2013)
Cell
, vol.155
, pp. 515-518
-
-
Hendrix, C.1
-
8
-
-
84866283847
-
Emtricitabine-tenofovir concentrations and preexposure prophylaxis efficacy in men who have sex with men
-
Anderson P, Glidden D, Liu A, et al. Emtricitabine-tenofovir concentrations and preexposure prophylaxis efficacy in men who have sex with men. Sci Transl Med 2012; 4:151ra125.
-
(2012)
Sci Transl Med
, vol.4
, pp. 151ra125
-
-
Anderson, P.1
Glidden, D.2
Liu, A.3
-
9
-
-
84950274249
-
Predicting effective truvada prep dosing strategies with a novel pk-pd model incorporating tissue active metabolites and endogenous nucleotides (en) [abstract oa22. 06 lb]
-
28-31 October; Cape Town, South Africa
-
Cottrell M, Yang K, Prince H, et al. Predicting effective truvada PrEP dosing strategies with a novel PK-PD model incorporating tissue active metabolites and endogenous nucleotides (EN) [Abstract OA22. 06 LB]. HIV Research for Prevention (HIV R4P); 28-31 October 2014; Cape Town, South Africa.
-
(2014)
HIV Research for Prevention (HIV R4P
-
-
Cottrell, M.1
Yang, K.2
Prince, H.3
-
10
-
-
83155177076
-
Penetration of tenofovir and emtricitabine in mucosal tissues: Implications for prevention of HIV-1 transmission
-
Patterson K, Prince H, Kraft E, et al. Penetration of tenofovir and emtricitabine in mucosal tissues: implications for prevention of HIV-1 transmission. Sci Transl Med 2011; 3:112re114.
-
(2011)
Sci Transl Med
, vol.3
, pp. 112re114
-
-
Patterson, K.1
Prince, H.2
Kraft, E.3
-
11
-
-
84931273616
-
Pharmacokinetics of longacting tenofoviralafenamide (gs-7340) subdermal implant for HIV prophylaxis
-
Gunawardana M, Remedios-ChanM, Miller C, et al. Pharmacokinetics of longacting tenofoviralafenamide (GS-7340) subdermal implant for HIV prophylaxis. Antimicrob Agents Chemother 2015; AAC-00656.
-
(2015)
Antimicrob Agents Chemother
, pp. AAC-00656
-
-
Gunawardana, M.1
Remedios-Chan, M.2
Miller, C.3
-
12
-
-
84896769378
-
Long-Acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus
-
Andrews C, Spreen W,Mohri H, et al. Long-Acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus. Science 2014; 343:1151-1154.
-
(2014)
Science
, vol.343
, pp. 1151-1154
-
-
Andrews, C.1
Spreen, W.2
Mohri, H.3
-
13
-
-
84950301595
-
Correlation of in vivo cabotegravir concentration and prevention of siv in macaques [abstract 966lb]
-
23-26 February; Seattle, Washington
-
Spreen W, Lowry A, Pal R, et al. Correlation of in vivo cabotegravir concentration and prevention of SIV in macaques [Abstract 966LB]. 22nd Conference on Retroviruses and Opportunistic Infections (CROI); 23-26 February 2015; Seattle, Washington.
-
(2015)
22nd Conference on Retroviruses and Opportunistic Infections (CROI
-
-
Spreen, W.1
Lowry, A.2
Pal, R.3
-
14
-
-
84927638575
-
744 and rilpivirine as two-drug oral maintenance therapy: Lai116482 (latte) week 48 results [abstract 91lb]
-
3-6 March; Boston, Massachusetts
-
Margolis D, Brinson C, Eron J, et al. 744 and rilpivirine as two-drug oral maintenance therapy: Lai116482 (latte) week 48 results [Abstract 91LB]. 21st Conference on Retroviruses and Opportunistic Infections (CROI); 3-6 March 2014; Boston, Massachusetts.
-
(2014)
21st Conference on Retroviruses and Opportunistic Infections (CROI
-
-
Margolis, D.1
Brinson, C.2
Eron, J.3
-
15
-
-
84950245690
-
Cabotegravir and rilpivirine as 2-drug oral maintenance therapy: Latte w96 results [abstract 554lb]
-
23-26 February; Seattle, Washington
-
Margolis D, Brinson C, Smith G, et al. Cabotegravir and rilpivirine as 2-drug oral maintenance therapy: LATTE W96 results [Abstract 554LB]. 22nd Conference on Retroviruses and Opportunistic Infections (CROI); 23-26 February 2015; Seattle, Washington.
-
(2015)
22nd Conference on Retroviruses and Opportunistic Infections (CROI
-
-
Margolis, D.1
Brinson, C.2
Smith, G.3
-
16
-
-
75749118495
-
Tmc278, a next-generation nonnucleoside reverse transcriptase inhibitor (nnrti), active against wild-type and nnrtiresistant HIV-1
-
Azijn H, Tirry I, Vingerhoets J, et al. TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTIresistant HIV-1. Antimicrob Agent Chemother 2010; 54:718-727.
-
(2010)
Antimicrob Agent Chemother
, vol.54
, pp. 718-727
-
-
Azijn, H.1
Tirry, I.2
Vingerhoets, J.3
-
17
-
-
67650456668
-
Rilpivirine: A novel nonnucleoside reverse transcriptase inhibitor
-
Garvey L, Winston A. Rilpivirine: A novel nonnucleoside reverse transcriptase inhibitor. Expert Opin Investig Drugs 2009; 18:1035-1041.
-
(2009)
Expert Opin Investig Drugs
, vol.18
, pp. 1035-1041
-
-
Garvey, L.1
Winston, A.2
-
18
-
-
84950250095
-
Preclinical evaluation of tmc-278la, a long-Acting formulation of rilpivirine, demonstrates significant protection from vaginal HIV infection [abstract oa03. 01]
-
28-31 October Cape Town, South Africa
-
Snyder O, Vincent H, Lachau-Durant S, et al. Preclinical evaluation of TMC-278LA, a long-Acting formulation of rilpivirine, demonstrates significant protection from vaginal HIV infection [Abstract OA03. 01]. HIV Research for Prevention (HIV R4P); 28-31 October 2014; Cape Town, South Africa.
-
(2014)
HIV Research for Prevention (HIV R4P
-
-
Snyder, O.1
Vincent, H.2
Lachau-Durant, S.3
-
19
-
-
84907878697
-
A compartmental pharmacokinetic evaluation of long-Acting rilpivirine in HIV-negative volunteers for preexposure prophylaxis
-
Jackson A, Else L, Mesquita P, et al. A compartmental pharmacokinetic evaluation of long-Acting rilpivirine in HIV-negative volunteers for preexposure prophylaxis. Clin Pharmacol Ther 2014; 96:314-323.
-
(2014)
Clin Pharmacol Ther
, vol.96
, pp. 314-323
-
-
Jackson, A.1
Else, L.2
Mesquita, P.3
-
20
-
-
84942846401
-
A phase 1 open label safety, acceptability, pharmacokinetic, and pharmacodynamic study of intramuscular tmc278la (the mwri-01 study) [abstract oa27. 06 lb]
-
28-31 October Cape Town, South Africa
-
McGowan I, Siegel A, Duffill K, et al. A phase 1 open label safety, acceptability, pharmacokinetic, and pharmacodynamic study of intramuscular TMC278LA (the MWRI-01 study) [Abstract OA27. 06 LB]. HIV Research for Prevention (HIV R4P); 28-31 October 2014; Cape Town, South Africa.
-
(2014)
HIV Research for Prevention (HIV R4P
-
-
McGowan, I.1
Siegel, A.2
Duffill, K.3
-
21
-
-
84950294750
-
Selection of rilpivirine resistant HIV-1 in a seroconverter on long-Acting rilpivirine (tmc278la) from the lowest dose arm of the ssat 040 trial [abstract oa27. 01]
-
28-31 October; Cape Town, South Africa
-
Penrose K, Parikh U, Hamanishi K, et al. Selection of rilpivirine resistant HIV-1 in a seroconverter on long-Acting rilpivirine (TMC278LA) from the lowest dose arm of the SSAT 040 trial [Abstract OA27. 01]. HIV Research for Prevention (HIV R4P); 28-31 October 2014; Cape Town, South Africa.
-
(2014)
HIV Research for Prevention (HIV R4P
-
-
Penrose, K.1
Parikh, U.2
Hamanishi, K.3
-
22
-
-
40649085987
-
Hormonal contraceptive discontinuation patterns according to formulation: Investigation of associations in an administrative claims database
-
Murphy P, Brixner D. Hormonal contraceptive discontinuation patterns according to formulation: investigation of associations in an administrative claims database. Contraception 2008; 77:257-263.
-
(2008)
Contraception
, vol.77
, pp. 257-263
-
-
Murphy, P.1
Brixner, D.2
-
23
-
-
34548679894
-
Assessing regional differences in contraceptive discontinuation, failure and switching in Brazil
-
Leite IC, Gupta N. Assessing regional differences in contraceptive discontinuation, failure and switching in Brazil. Reprod Health 2007; 4:6.
-
(2007)
Reprod Health
, vol.4
, pp. 6
-
-
Leite, I.C.1
Gupta, N.2
-
24
-
-
84942191100
-
Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (latte): A randomised, phase 2b, dose-ranging trial
-
Margolis DA, Brinson CC, Smith GHR, et al. Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised, phase 2b, dose-ranging trial. Lancet 2015; 15:1145-1155.
-
(2015)
Lancet
, vol.15
, pp. 1145-1155
-
-
Margolis, D.A.1
Brinson, C.C.2
Smith, G.H.R.3
-
25
-
-
84943155332
-
Meta-Analysis of safety data from 8 clinical studies with gsk1265744 an HIV integrase inhibitor dosed orally or as injection of long-Acting parenteral nanosuspension (lap) [abstract 1752]
-
10-13 September 2013 Denver, Colorado
-
Lou Y, Gould E, Chen S, et al. Meta-Analysis of safety data from 8 clinical studies with GSK1265744, an HIV integrase inhibitor, dosed orally or as injection of long-Acting parenteral nanosuspension (LAP) [Abstract 1752]. 53rd ICAAC Interscience Conference on Antimicrobial Agents and Chemotherapy; 10-13 September 2013; Denver, Colorado.
-
53rd ICAAC Interscience Conference on Antimicrobial Agents and Chemotherapy
-
-
Lou, Y.1
Gould, E.2
Chen, S.3
-
26
-
-
84886473877
-
Pharmacokinetics, safety, and monotherapy antiviral activity of gsk1265744, an HIV integrase strand transfer inhibitor
-
Spreen W, Min S, Ford S, et al. Pharmacokinetics, safety, and monotherapy antiviral activity of GSK1265744, an HIV integrase strand transfer inhibitor. HIV Clin Trials 2013; 14:192-203.
-
(2013)
HIV Clin Trials
, vol.14
, pp. 192-203
-
-
Spreen, W.1
Min, S.2
Ford, S.3
-
27
-
-
84860455337
-
Long-term efficacy, safety, and tolerability of rilpivirine (rpv, tmc278) in HIV type 1-infected antiretroviralnaive patients: Week 192 results from a phase iib randomized trial
-
Wilkin A, Poznaik AL, Morales-Ramirez J, et al. Long-term efficacy, safety, and tolerability of rilpivirine (RPV, TMC278) in HIV type 1-infected antiretroviralnaive patients: Week 192 results from a phase IIb randomized trial. AIDS Res Hum Retroviruses 2012; 28:437-446.
-
(2012)
AIDS Res Hum Retroviruses
, vol.28
, pp. 437-446
-
-
Wilkin, A.1
Poznaik, A.L.2
Morales-Ramirez, J.3
-
28
-
-
84950290079
-
Ethical considerations regarding oral preexposure prophylaxis in HIV prevention trials
-
Sugarman J. Ethical considerations regarding oral preexposure prophylaxis in HIV prevention trials. Curr Opin HIV AIDS 2016; 11:109-115.
-
(2016)
Curr Opin HIV AIDS
, vol.11
, pp. 109-115
-
-
Sugarman, J.1
|