Efficacy of Chloroquine as a first line agent in the treatment of uncomplicated malaria due to Plasmodium vivax in children and treatment practices in Pakistan: A pilot study

Journal of the Pakistan Medical Association

Volumn 66, Issue 1, 2016, Pages 30-33

  Waqar, Talal ^a   Khushdil, Arshad ^b   Haque, Khalid ^c  

^a National University of Medical Sciences   (Pakistan)

^b CMH   (Pakistan)

^c NONE   (United States)

Author keywords

Chloroquine; Pakistan; Vivax malaria; WHO

Indexed keywords

ARTEMISIN; C REACTIVE PROTEIN; CHLOROQUINE; PYRIMETHAMINE PLUS SULFADOXINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; LACTONE;

ARTICLE; BLOOD CELL COUNT; BLOOD CULTURE; CHILD; CLINICAL ARTICLE; HEALTH SURVEY; HUMAN; INFANT; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; MALARIA; PAKISTAN; PARASITEMIA; PEDIATRICIAN; PHYSICIAN ATTITUDE; PILOT STUDY; PLASMODIUM VIVAX; PRACTICE GUIDELINE; QUASI EXPERIMENTAL STUDY; TELEPHONE INTERVIEW; TREATMENT RESPONSE; CLINICAL PRACTICE; COMBINATION DRUG THERAPY; FEMALE; MALARIA, VIVAX; MALE; PRESCHOOL CHILD; PROSPECTIVE STUDY; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME;

ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; CHLOROQUINE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INFANT; LACTONES; MALARIA, VIVAX; MALE; PAKISTAN; PEDIATRICIANS; PILOT PROJECTS; PRACTICE PATTERNS, PHYSICIANS'; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84950145517     PISSN: 00309982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Butler D. Malaria. Nature 2013 [incomplete match not found on pubmed and google]
2. World Health Organization. World malaria report: 2011. Geneva: The Organization; 2011.[Online] [cited 2015 March 20]. Available from:URL http://www.who.int/malaria/world_malaria_report_2011/WMR2011_noprofiles_lowres.pdf.
3. World Health Organization.World malaria report 2013.
4. Pakistan. Directorate of Malaria Control Program, Malaria No More, 2011.[Online] [cited 2015 March 20]. Available from: URL: http://www.dmc.gov.pk/index.php?option=com_content&view=article&id=55&Itemid=88
5. Kakar Q, Khan MA, Bile KM. Malaria control in Pakistan: new tools at hand but challenging epidemiological realities. East Mediterr Health J 2010; 16: S54-S60.
6. Malik M, Azmi M, Hassali A, Shafie AA, Hussain A. Why Don ' t Medical Practitioners Treat Malaria Rationally?? A Qualitative Study from Pakistan. Trop J Pharm Res 2012; 11: 673-81
7. Khattak AA, Venkatesan M, Khatoon L, Quattara A, Kenefic LJ, Nadeem MF, et al. Prevalence and patterns of antifolate and chloroquine drug resistance markers in Plasmodium vivax across Pakistan. Malaria J 2013; 12: 310.
8. Khatoon L, Baliraine FN, Malik SA, Yan G. Sequence analysis of genes associated with resistance to chloroquine and sulphadoxine pyrimethamine in P. falciparum and P. vivax isolates fromthe Bannu district of Pakistan. Brazil J Infect Dis 2013; 7: 596-600.
9. Khatoon L, Baliraine FN, Bonizzoni M, Malik SA, Yan G. Prevalence of Antimalarial Drug Resistance Mutations in Plasmodium vivax and P. falciparum from a Malaria-Endemic Area of Pakistan. Am J Trop Med Hyg 2009; 81: 525-8.
10. Leslie T, Mayan MI, Hasan MA, Safi MH, Klinkenberg E, Whitty CJ, et al. Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the Treatment of Plasmodium vivax Malaria in Afghanistan and Pakistan: a randomized controlled trial. JAMA 2007; 297: 2201-9.
11. Awab GR, Pukrittayakamee S, Imwong M, Dondorp AM, Woodrow CJ, Lee SJ. et al. Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial. Malaria J 2010; .9: 105
12. World Health Organization. Guidelines for the treatment of malaria, 2nd ed. WHO Library Cataloguing-in-Publication Data; 2010: 197.
13. Chareonkul C, Khun VL, Boonshuyar C. Rational drug use in Cambodia: study of three pilot health centers in Kampong Thom Province. Southeast Asian J TropMed Public Health 2002; 33: 418-24.
14. Abuaku BK, Koram KA, Binka FN. Antimalarial prescribing practices: A challenge tomalaria control in Ghana.Med Princ Pract 2005; 14: 332-7.
15. Sharma VP. Battling the malaria iceberg with chloroquine in India. Malaria J 2007; 6: 105.
16. Valecha N, Joshi H, Eapen A, Ravinderan J, Kumar A, Prajapati SK. Therapeutic efficacy of chloroquine in Plasmodiumvivax fromareas with different epidemiological patterns in India and their Pvdhfr genemutation pattern. Trans R Soc TropMed Hyg 2006; 100: 831-7.