Identification of O-linked glycoproteins binding to the lectin Helix pomatia agglutinin as markers of metastatic colorectal cancer

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Peiris, Diluka ^a   Ossondo, Marlène ^b   Fry, Simon ^a   Loizidou, Marilena ^c   Smith Ravin, Juliette ^b   Dwek, Miriam V ^a  

^a UNIVERSITY OF WESTMINSTER   (United Kingdom)

^b UNIVERSITÉ DES ANTILLES ET DE LA GUYANE   (France)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTININ; BIOLOGICAL MARKER; GLYCOPROTEIN; HELIX POMATIA AGGLUTININ; K RAS PROTEIN; LIPOCORTIN 4; PROTEIN P53; UNCLASSIFIED DRUG; HELIX LECTIN; KRAS PROTEIN, HUMAN; LECTIN; PROTEIN BINDING; PROTEIN P21; TUMOR MARKER;

ARTICLE; BINDING AFFINITY; CANCER SURVIVAL; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; CORRELATIONAL STUDY; GEL ELECTROPHORESIS; HELIX POMATIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; METASTATIC COLORECTAL CANCER; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEOMICS; SURVIVAL TIME; COLORECTAL TUMOR; DNA MUTATIONAL ANALYSIS; GENETICS; GLYCOSYLATION; KAPLAN MEIER METHOD; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; METABOLISM; METASTASIS; PATHOLOGY; REPRODUCIBILITY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BIOMARKERS, TUMOR; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LECTINS; NEOPLASM METASTASIS; PROTEIN BINDING; PROTEOMICS; PROTO-ONCOGENE PROTEINS P21(RAS); REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84949745937     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138345     Document Type: Article

References (40)

1. Schima W, Kulinna C, Langenberger H, Ba-Ssalamah A. Liver metastases of colorectal cancer: US, CT or MR? Cancer Imag. 2005, 5:S149-S155
2. Brooks SA, Leathem AJC, Prediction of lymph node involvement in breast cancer by detection of altered glycosylation in the primary tumour, Lancet. 1991, 338:71-74. PMID: 1712062
3. Ghazarian H, Idoni B, Oppenheimer SB, A glycobiology review: carbohydrates, lectins, and implications in cancer therapeutics, Acta Histochem. 2011, 113:236-247. doi: 10.1016/j.acthis.2010.02.004 PMID: 20199800
4. Bhattacharyya L, Brewer CF, Lectin-carbohydrate interactions. Studies of the nature of hydrogen bonding between D-galactose and certain D-galactose-specific lectins, and between D-mannose and concanavalin A, Euro. J. Biochem. 1988, 176:207-212.
5. Sanchez JF, Lescar J, Chazalet V, Audfray A, Gagnon J, Alvarez R, et al, Biochemical and structural analysis of Helix pomatia agglutinin-A hexameric lectin with a novel fold, J Biol. Chem. 2006, 281:20171-20180. PMID: 16704980
6. Markiv A, Peiris D, Curley GP, Odell M, Dwek MV., Identification, cloning, and characterization of two N-acetylgalactosamine-binding lectins from the albumen gland of Helix pomatia, J. Biol. Chem. 2011, 286: 20260-20266. doi: 10.1074/jbc.M110.184515 PMID: 21372134
7. Leathem A, Dokal I, Atkins N, Lectin binding to normal and malignant breast tissue, Diagn. Histopathol. 1983, 6: 171-180.
8. Fukutomi T, et al, Prognostic contributions of Helix pomatia and carcinoembryonic antigen staining using histochemical techniques in breast carcinomas, Jpn. J. Clin. Onco. 1989, 19: 127-134.
9. Ikeda Y, Itabashi M, Tsugane S, Yamamoto H, Nanasawa T, Hirota T., Prognostic value of the histochemical expression of Helix pomatia agglutinin in advanced colorectal cancer; A univariate and multivariate analysis. Dis. Colon Rectum. 1994, 37: 181-184. PMID: 8306842
10. Schumacher U, Mukhtar D, Stehling P, Reutter W., Is the lectin binding pattern of human breast and colon cancer cells influenced by modulators of sialic acid metabolism? Histochem. Cell Biol. 1996, 106: 599-604. PMID: 8985749
11. Schnegelsberg B, Schumacher U, Valentiner U, Lectin histochemisry of metastasizing and Non-metastasizing breast and colon cells, Anticancer Res. 2011, 31:1589-1598. PMID: 21617214
12. Saint-Guirons J, Zeqiraj E, Schumacher U, Greenwell P, Dwek M., Proteome analysis of metastatic colorectal cancer cells recognised by the lectin Helix pomatia agglutinin (HPA), Proteomics, 2007: 7: 4802-4809.
13. Rambaruth NDS, Greenwell P, Dwek MV, The lectin Helix pomatia agglutinin recognises O-GlcNAc containing glycoproteins in human breast cancer, Glycobiology 2012, 22: 839-848. doi: 10.1093/glycob/cws051 PMID: 22322011
14. Laemmli UK, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 1970, 227: 680-685. PMID: 5432063
15. Candiano G, Bruschi M, Musante L, Santucci L, Ghiggeri GM, Carnemolla B, et al, Blue Silver: A very sensitive colloidal coomassie G-250 staining for proteome analysis, Electrophoresis, 2004, 25:1327-1333. PMID: 15174055
16. Görg A, Obermaier C, Boguth G, Harder A, Scheibe B, Wildgruber R, et al, The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 2000, 21: 1037-1053. PMID: 10786879
17. Arrington AK, Heinrich EL, Lee W, Duldulao M, Patel S, Sanchez J, et al, Prognostic and Predictive Roles of KRAS Mutation in Colorectal Cancer, Int. J. Mol. Sci. 2012, 13: 12153-12168 doi: 10.3390/ijms131012153 PMID: 23202889
18. Markiv A, Rambaruth ND, Dwek MV, Beyond the genome and proteome: targeting protein modifications in cancer, Curr. Opin Pharmacol. 2012, 12: 408-413. doi: 10.1016/j.coph.2012.04.003 PMID: 22560919
19. Rambaruth NDS, Dwek MV, Cell surface glycan-lectin interactions in tumor metastasis, Acta Histochem. 2011, 113: 591-600. doi: 10.1016/j.acthis.2011.03.001 PMID: 21501858
20. Kim Y, Son OL, Lee JY, Kim SH, Oh S, Lee YS, et al, Lectin precipitation using phytohemagglutinin-L4 coupled to avidin-agarose for serological biomarker discovery in colorectal cancer, Proteomics 2008, 8: 3229-3235. doi: 10.1002/pmic.200800034 PMID: 18633972
21. Drake MP, Cho W, Li B, Prakobphol A, Johansen E, Anderson NL, et al, Sweetening the pot: adding glycosylation to the biomarker discovery equation. Clin. Chem. 2010, 56: 223-236. doi: 10.1373/clinchem.2009.136333 PMID: 19959616
22. Schumacher U, Higgs D, Loizidou M, Pickering R, Leathem A, Taylor I., Helix pomatia binding is a useful prognostic indicator in colorectal carcinoma, Cancer 1994, 74: 3104-3107. PMID: 7982174
23. Brooks SA, Lymboura M, Schumacher U, Leathem AJ., Breast cancer: methodology makes a difference, J. Histochem. Cytochem. 1996, 44: 519-524. PMID: 8627008
24. Moss SE, Morgan RO, The Annexins, Genome Biol. 2004, 5: 219.1-219.9 PMID: 15059252
25. Gerke V, Moss SE, Annexins: from structure to function, Physiol. Rev. 2002, 82: 331-371.
26. Yeoh L, Dharmaraj S, Gooi BH, Singh M, Gam LH., Chemometrics of differentially expressed proteins from colorectal cancer patients. World J. Gastroentero. 2011, 28: 2096-2103.
27. Alfonso P, Cañamero M, Fernández-Carbonié F, Núñez A, Casal JI., Proteome analysis of membrane fractions in colorectal carcinomas by using 2-DE-DIGE saturation labelling, J. Proteome Res. 2008, 7: 4247-4255. doi: 10.1021/pr800152u PMID: 18707159
28. Duncan R, Carpenter B, Main LC, Telfer C, Murray GI, Characterisation and protein expression profiling of annexins in colorectal cancer, Br J. Cancer. 2008, 98: 426-433. PMID: 18071363
29. Zimmerman U, Balabanov S, Giebel J, Teller S, Junker H, Schmoll D, Protzel C, et al, Increased expression and altered location of annexin A4 in renal clear cell carcinoma: a possible role in tumour dissemination, Cancer Lett. 2004, 209: 111-118. PMID: 15145526
30. Zhang X, Liu S, Guo C, Zong J, Sun MZ, The association of annexin A2 and cancers. Clin. Transl. Oncol. 2012, 14: 634-640. doi: 10.1007/s12094-012-0855-6 PMID: 22855149
31. Guzman-Aranguez A, Olmo N, Turnay J, Lecona E, Pérez-Ramos P, López de Silanes I, et al, Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5, J. Cell Biochem. 2005, 94: 178-193. PMID: 15526283
32. Xue G, Hao LQ, Ding FX, Mei Q, Huang JJ, Fu CG, et al, Expression of Annexin A5 is associated with higher tumour stage and poor prognosis in colorectal adenocarcinomas, J. Clin. Gastroenterol. 2009, 43: 831-837. doi: 10.1097/MCG.0b013e31819cc731 PMID: 19461527
33. Bustin SA, Li SR, Dorudi S, Expression of the Ca2+-activated chloride channel genes CLCA1 and CLCA2 is downregulated in human colorectal cancer, DNA Cell. Biol. 2001, 20: 331-338. PMID: 11445004
34. Abdel-Ghany M, Cheng HC, Elble RC, Pauli BU, The breast cancer β4 integrin and endothelial human CLCA2 mediate lung metastasis, J. Biol. Chem. 2001, 276: 25438-25446. PMID: 11320086
35. Hart G, Slawson C, Ramirez-Correa G, Lagerlof O, Crosstalk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription and chronic disease, Annu. Rev. Biochem. 2011, 80: 825-858. doi: 10.1146/annurev-biochem-060608-102511 PMID: 21391816
36. Yehezkel G, Cohen L, Kliger A, Manor E, Khalaila I, O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-β-D-glucosaminidase silencing on cell phenotype and transcriptome, J. Biol. Chem. 2012, 287: 28755-28769. doi: 10.1074/jbc.M112.345546 PMID: 22730328
37. Yang WH, Kim JE, Nam HW, Ju JW, Kim HS, Kim YS, et al, Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability, Nat. Cell Biol. 2006, 8: 1074-1083. PMID: 16964247
38. Mi W, Gu Y, Han C, Liu H, Fan Q, Zhang X, Cong Q, et al, O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy, Biochim. Biophys. Acta. 2011, 1812: 514-519. doi: 10.1016/j.bbadis.2011.01.009 PMID: 21255644
39. Kijima M, Togo S, Ichikawa Y, Miura M, Yamagishi S, Matsuo K, et al, Clinical significance of serum CEA protein and CEA mRNA after resection of colorectal liver metastases, Anticancer Res. 2005, 25: 1327-1332. PMID: 15865086
40. Li N, Chen X, Wan X, Luo X, Han L, Zhou M, Yin D, et al, Relationship between expression of CEA, E-cadherin and liver metastasis in colorectal cancer, Chin. J. Clin. Oncol. 2008, 5:429-432.