Changes of ribbon synapses number of cochlear hair cells in C57BL/6J mice with ageΔ

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 10, 2015, Pages 19058-19064

  Jiang, Xing Wang ^a   Li, Xiao Rui ^b   Zhang, Yan Ping ^a  

^a 309TH HOSPITAL OF PLA   (China)

^b Department of Otolaryngology   (China)

Author keywords

C57BL 6J mice; Inner hair cell; Ribbon synapse

Indexed keywords

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BASILAR MEMBRANE; COCHLEA; CONFOCAL LASER MICROSCOPY; IMAGE RECONSTRUCTION; IMMUNOHISTOCHEMISTRY; INNER HAIR CELL; MOUSE; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRESBYACUSIS; PRESYNAPTIC MEMBRANE; SYNAPSE; THREE DIMENSIONAL IMAGING;

EID: 84949665324     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Francis HW, Rivas A, Lehar M and Ryugo DK. Two types of afferent terminals innervate cochlear inner hair cells in C57BL/6J mice. Brain Res 2004; 1016: 182-194.
2. Li SN, Jiang XJ, Liu K and Ren C. Ribbon synapse of inner hair cell. Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008; 43: 391-394.
3. Khimich D, Nouvian R, Pujol R, Tom Dieck S, Egner A, Gundelfinger ED and Moser T. Hair cell synaptic ribbons are essential for synchronous auditory signalling. Nature 2005; 434: 889-894.
4. Jing Z, Rutherford MA, Takago H, Frank T, Fejtova A, Khimich D, Moser T and Strenzke N. Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse. Neurosci 2013; 33: 4456-4467.
5. Singer W, Zuccotti A, Jaumann M, Lee SC, Panford-Walsh R, Xiong H, Zimmermann U, Franz C, Geisler HS, Köpschall I, Rohbock K, Varakina K, Verpoorten S, Reinbothe T, Schimmang T, Rüttiger L and Knipper M. Noise-induced inner hair cell ribbon loss disturbs central arcobilization: a novel molecular paradigm for understanding tinnitus. Mol Neurobiol 2013; 47: 261-279.
6. Li SN, Liu K, Gao J, Ren C and Jiang XJ. Three-dimensional Reconstruction Model in Counting Ribbon Synapse in Cochlear Inner Hair Cell. Journal of China Medical University 2008; 5: 580-582.
7. Zenisek D, Davila V, Wan L and Almers W. Imaging calcium entry sites and ribbon structures in two presynaptic cells. J Neurosci 2003; 23: 2538-2548.
8. Rodríguez-Contreras A and Yamoah EN. Effects of permeant ion concentrations on the gating of L-type Ca2+ channels in hair cells. Biophys J 2003; 84: 3457-3469.
9. Sidi S, Busch-Nentwich E, Friedrich R, Schoenberger U and Nicolson T. Gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses. J Neurosci 2004; 24: 4213-4223.
10. Stamataki S, Francis HW, Lehar M, May BJ and Ryugo DK. Synaptic alterations at inner hair cells precede spiral ganglion cell loss in aging C57BL/6J mice. Hear Res 2006; 221: 104-118.
11. Noben-Trauth K, Zheng QY and Johnson KR. Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat Genet 2003; 35: 21-23.
12. Siemens J, Lillo C, Dumont RA, Reynolds A, Williams DS, Gillespie PG and Müller U. Cadherin 23 is a component of the tip link in hair-cell stereocilia. Nature 2004; 428: 950-955.
13. Di Palma F, Holme RH, Bryda EC, Belyantseva IA, Pellegrino R, Kachar B, Steel KP and Noben-Trauth K. Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D. Nat Genet 2003; 27: 103-107.
14. Liu K, Jiang X, Shi C, Shi L, Yang B, Shi L, Xu Y, Yang W and Yang S. Cochlear Inner Hair Cell Ribbon Synapse is the Primary Target of Ototoxic Aminoglycoside Stimuli. Mol Neurobiol 2013; 48: 647-654.