Bioactivity of umbilical cord blood dendritic cells and anti-leukemia effect

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 10, 2015, Pages 19725-19730

  Wei, Xu Cang ^a   Yang, Di Di ^a   Han, Xiu Rui ^a   Zhao, Yu An ^a   Li, Yan Chun ^a   Zhang, Li Jie ^a   Wang, Jiu Ju ^a  

^a SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Co culture; Cytokine induced killer cells (CIK); Cytotoxicity; Dendritic cells (DCs); Leukemia; Umbilical cord blood

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL COUNT; CELL KILLING; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE INDUCED KILLER CELL; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT REJECTION; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IMMUNOTHERAPY; LEUKEMIA CELL LINE; MONONUCLEAR CELL; MTT ASSAY; PHENOTYPE; PROTEIN EXPRESSION; UMBILICAL CORD BLOOD DENDRITIC CELL;

EID: 84949643455     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Rosenblatt J and Avigan D. Can leukemia-derived dendritic cells generate antileukemia immunity? Expert Rev Vaccines 2006; 5: 467-472.
2. Linn YC and Hui KM. Cytokine induced Killer cells: NK-like T cells with cytotolytic specificity against leukemia. Leuk Lymphoma 2003; 44: 1457-1462.
3. Wei XC, Zhai XH, Han XR, Yang DD and Zhao WL. DC, CIK cells in vitro biological activity and anti-leukemia effect research (UK). Journal of Experimental Hematology 2008; 16: 1150-1153.
4. Zhao ZL, Chai YH, He HL, Wei XC, Wang T, Xing PN and Li MS. Myeloid leukemia source for CML interferon a dendritic cells express Th cytokines or when the CCR7 (English). Journal of Experimental Hematology 2008; 16: 401-405.
5. Zoll B, Lefterova P, Ebert O, Huhn D, Von Ruecker A and Schmidt-Wolf IG. Modulation of cell surface markers on NK-like T lymphocytes by using IL-2, IL-7 or IL-12 in vitro stimulation. Cytokine 2000; 12: 1385-1390.
6. Märten A, Ziske C, Schöttker B, Renoth S, Weineck S, Buttgereit P, Schakowski F, von Rücker A, Sauerbruch T and Schmidt-Wolf IG. Interactions between dendritic cells and cytokine-induced Killer cells lead to an activation of both populations. J Immunother 2001; 24: 502-510.
7. Linn YC and Hui KM. Cytokine-induced killer cells: NK-like T cells with cytotolytic specificity against leukemia. Leuk Lymphoma 2003; 44: 1457-1462.
8. Schmidt J, Eisold S, Büchler MW and Märten A. Dendritic cells reduce number and function of CD4+CD25+ cells in cytokine-induced killer cells deried from patients with pancreatic carcinoma. Cancer Immunol Immunother 2004; 53: 1018-1026.
9. Fujii S, Shimizu K, Kronenberg M, Steinman RM. Prolonged IFN-gamma-producing NKT response indued with alpha-galactosylceramide-loaded DCs. Nat Immunol 2002; 3: 867-874.
10. Cooper MA, Fehniger TA, Fuchs A. Nk cell and DC interactions. Immunol 2004; 5: 47-52.
11. Nishimura T, Kitamura H, Iwakabe K, Yahata T, Ohta A, Sato M, Takeda K, Okumura K, Van Kaer L, Kawano T, Taniguchi M, Nakui M, Sekimoto M and Koda T. The interface between innate and acquired immunity: glycolipid antigen presentation by CD1a-expressing dendritic cells to NKT cells induces the differentiation of antigen specific cytotoxic T lymphocytes. Int Immunol 2000; 12: 987-994.