Effect of myrrh and thyme on Trichinella spiralis enteral and parenteral phases with inducible nitric oxide expression in mice

Memorias do Instituto Oswaldo Cruz

Volumn 110, Issue 8, 2015, Pages 1035-1041

  Attia, Rasha A H ^a   Mahmoud, Abeer E ^a   Farrag, Haiam Mohammed Mahmoud ^a   Makboul, Rania ^b   Mohamed, Mona Embarek ^c   Ibraheim, Zedan ^d  

^a ASSIUT UNIVERSITY   (Egypt)

^b Assiut University   (Egypt)

^c Assiut University Faculty of Medicine   (Egypt)

^d Assiut University   (Egypt)

Author keywords

Albendazole; Cytotoxicity tests; Enteral, parenteral phases; iNOS; Limulus amoebocyte lysate assay; Myrrh; Thyme; Trichinella spiralis

Indexed keywords

ALBENDAZOLE; ANTINEMATODAL AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; MYRRH OIL; TERPENE;

ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; COMMIPHORA; DRUG EFFECTS; ENZYMOLOGY; FIBROBLAST; IMMUNOHISTOCHEMISTRY; LARVA; METABOLISM; PARASITOLOGY; SKELETAL MUSCLE; SMALL INTESTINE; THYMUS (PLANT); TRICHINELLA SPIRALIS;

ALBENDAZOLE; ANIMALS; ANTINEMATODAL AGENTS; CELL LINE; COMMIPHORA; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; INTESTINE, SMALL; LARVA; MICE, INBRED BALB C; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE TYPE II; TERPENES; THYMUS PLANT; TRICHINELLA SPIRALIS;

EID: 84949639699     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/0074-02760150295     Document Type: Article

References (47)

1. Abd El Aal AA, EI-Arousy M, lssa RM 2003. Nitric oxide release during experimental schistosomiasis and trichinellosis. Egypt J Med Sci 24: 343-354.
2. Abu El Ezz NM 2005. Effect of Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats. J Egypt Soc Parasitol 35: 511-523.
3. Ahmad A, Khan A, Yousuf S, Khan LA, Manzoor N 2010. Proton translocating ATPase mediated fungicidal activity of eugenol and thymol. Fitoterapia 81: 1157-1162.
4. Ascenzi P, Gradoni L 2002. Nitric oxide limits parasite development in vectors and in invertebrate intermediate hosts. IUMBM Life 53: 121-123.
5. Basyoni MM, El-Sabaa AA 2013. Therapeutic potential of myrrh and ivermectin against experimental Trichinella spiralis infection in mice. Korean J Parasitol 51: 297-304.
6. Boczon’ K, Wandurska-Nowak E, Wierzbicki A, Frydrychowicz M, Mozer-Lisewska I, Zeromski J 2004. mRNA expression and immunohistochemical localization of inducible nitric oxide synthase (NOS-2) in the muscular niche of Trichinella spiralis. Folia Histochem Cytobiol 42: 209-213.
7. Boczon’ K, Wandurska-Nowak E, Szulc M 2002. The effect of albendazole on iNOS-derived NO production in experimental trichinellosis. Helminthol 39: 17-21.
8. Boczon’ K, Wargin B 2000. Inducible nitric oxide synthase in the muscles of Trichinella sp. infected mice treated with glucocorticoid methylprednisolone. Comp Parasitol 67: 230-235.
9. Bruschi F, Lucchi NW 2001. Enzymatic antioxidant systems in helminth parasites: no doubt on their evasive role. Acta Parasitol 46: 233-241.
10. Caner A, Döşkaya M, Değirmenci A, Can H, Baykan S, Uner A, Başdemir G, Zeybek U, Gürüz Y 2008. Comparison of the effects of Artemisia vulgaris and Artemisia absinthium growing in western Anatolia against trichinellosis (Trichinella spiralis) in rats. Exp Parasitol 119: 173-179.
11. Chung MS, Joo KH, Quan FS, Kwon HS, Cho SW 2001. Efficacy of flubendazole and albendazole against Trichinella spiralis in mice. Parasite 8 (Suppl. 2): S195-S198.
12. Clark IA, Awburn MM, Whitten RO, Harper CG, Liomba NG, Mo- lyneux ME, Taylor TE 2003. Tissue distribution of migration inhibitory factor and inducible nitric oxide synthase in falciparum malaria and sepsis in African children. Malar J 2-6: 1-17.
13. Denham DA, Martinez AR 1970. Studies with methyridine and Trichinella spiralis. 2. The use of drugs to study the rate of larval production in mice. J Helminthol 44: 357-363.
14. Dolara P, Corte B, Ghelardini C, Pugliese AM, Cerbai E, Menichetti S, Lo Nostro A 2000. Local anaesthetic and antifungal properŧies of sesquiterpenes from myrrh. Planta Med 66: 356-358.
15. Dorman HJ, Deans SG 2000. Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J Appl Microbiol 88: 308-316.
16. EDQM Council of Europe 2014. European Pharmacopoeia. Available from: edqm.eu/en/european-pharmacopoeia-8th-edition-1563.html
17. Evans WC 2002. Trease & Evans’ Pharmacognosy, 15th ed., Elsevier, Edinburgh, 585 pp
18. Fathy FM 2011. Effect of mirazid (Commiphora molmol) on experimental giardiasis. J Egypt Soc Parasitol 41: 155-177.
19. Gamble HR 1996. Detection of trichinellosis in pigs by artificial digestion and enzyme immunoassay. J Food Prot 59: 295-298.
20. Goettsch W, Garssen J, Deijns A, De Gruijl FR, Van Loveren H 1994. UV-B exposure impairs resistance to infection by Trichinella spiralis. Environ Health Perspect 102: 298-301.
21. Gottstein B, Pozio E, Nöckler K 2009. Epidemiology, diagnosis, treatment, and control of trichinellosis. Clin Microbiol Rev 22: 127-145.
22. Hussaini SN, Hassanali HT 1987. Limulus amoebocyte lysate assay of endotoxin: a method for visual detection of the positive gel reaction. J Med Microbiol 24: 89-90.
23. Issa RM, Shalaby MA, Sabry HY, Hagag SH 2008. Estimation of nitric oxide level in mice infected by Trichinella spiralis. PUJ 1: 137-143.
24. Jarillo-Luna RA, Campos-Rodríguez R, Tsutsumi V 2002. Entamoeba histolytica: immunohistochemical study of hepatic amoebiasis in mouse. Neutrophils and nitric oxide as possible factors of resistance. Exp Parasitol 101: 40-56.
25. Kołodziej-Sobocińska M, Dvoroznakova E, Dziemian E, Machnicka-Rowińska B 2007. Trichinella spiralis reinfection: macrophage activity in BALB/c mice. Parasitol Res 101: 629-637.
26. Lawrence CE, Paterson JC, Wei XQ, Liew FY, Garside P, Kennedy MW 2000. Nitric oxide mediates intestinal pathology but not immune expulsion during Trichinella spiralis infection in mice. J Immunol 164: 4229-4234.
27. Long XC, Li YL, Ruppel A 2004. Expression of inducible nitric oxide synthase in the livers of mice infected with Schistosoma japonicum. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 22: 157-159.
28. Massoud A, EL Sisi S, Salama O, Massoud A 2001. Preliminary study of therapeutic efficacy of a new fasciolicidal drug derived from Commiphora molmol (myrrh). Am J Trop Med Hyg 65: 96-99
29. Mathela CS, Singh KK, Gupta VK 2010. Synthesis and in vitro antibacterial activity of thymol and carvacrol derivatives. Acta Pol Pharm 67: 375-380.
30. Mikus J, Harkenthal M, Steverding D, Reichling J 2000. In vitro effect of essential oils and isolated mono- and sesquiterpenes on Leishmania major and Trypanosoma brucei. Planta Med 66: 366-368.
31. Moazeni M, Saharkhiz MJ, Hosseini AA 2012. In vitro lethal effect of a jowan (Trachysperm umammi L.) essential oil on hydatid cyst protoscoleces. Vet Parasitol 187: 203-208.
32. Monib MEM, Shaheen MS, Galal LA, Farrag HM 2010. Role of T. spiralis adult and larval antigens in immunomodulation of nitric oxide (NO) in intestinal and muscular phase of trichinelosis. Assiut Med J 34: 147-158.
33. Moreira DL, Teixeira SS, Monteiro MH, De-Oliveira AA, Paumgartten FJR 2014. Traditional use and safety of herbal medicines. Rev Bras Farmacogn 24: 248-257.
34. Nasrabadi NT, Mirghasemi N, Bakhtiari N, Zarrinkoub N, Mirghasemi N 2012. Comparison of anti-parasitic effects of garden thyme (Thymus vulgaris) extract and metronidazole on Trichomonas gallinae. RPS 7 (Suppl.): S788.
35. Nassef NE, El-Sobky MM, Afifi AF 2010. Worm and larval burden, histopathological and ultrastructural evaluation of T. spiralis vaccination using crude worms and/or larvae antigens: Experimental studies. PUJ 3: 27-38.
36. Pozio E 2007. World distribution of Trichinella spp infections in animals and humans. Vet Parasitol 149: 3-21.
37. Repetto G, del Peso A, Zurita JL 2008. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat Protoc 3: 1125-1131.
38. Santoro GF, das Graças Cardoso M, Guimarães LG, Salgado AP, Menna-Barreto RF, Soares MJ 2007. Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure. Parasitol Res 100: 783-790.
39. Shalaby MA, Moghazy FM, Shalaby HA, Nasr SM 2010. Effect of methanolic extract of Balanites aegyptiaca fruits on enteral and parenteral stages of Trichinella spiralis in rats. Parasitol Res 107: 17-25.
40. Sheir Z, Nasr AA, Massoud A, Salama O, Badra GA, El-Shennawy H, Hassan N, Hammad SM 2001. A safe, effective, herbal antischistosomal therapy derived from myrrh. Am J Trop Med Hyg 65: 700-704
41. Shoheib ZS, Shamloula MM, Abdin AA, El-Segai O 2006. Role of α-chymotrypsin and colchicine as adjuvant therapy in experimental muscular trichinellosis: parasitological, biochemical and immunohistochemical study. EJMM 15: 773-790.
42. Siriyasatien P, Yingyourd P, Nuchprayoon S 2003. Efficacy of albendazole against early and late stage of Trichinella spiralis infection in mice. J Med Assoc Thai 86 (Suppl.): S257-S262.
43. Ündeğer U, Başaran A, Degen GH, Başaran NN 2009. Antioxidant activities of major thyme ingredients and lack of (oxidative) DNA damage in V79 Chinese hamster lung fibroblast cells at low levels of carvacrol and thymol. Food Chem Toxicol 47: 2037-2043.
44. Yadav AK, Temjenmongla 2006. Anthelmintic activity of Gynura angulosa DC against Trichinella spiralis infections in mice. PhOL 2: 299-306.
45. Yadav AK, Temjenmongla 2012. Efficacy of Lasia spinosa leaf ex- tract in treating mice infected with Trichinella spiralis. Parasitol Res 110: 493-498.
46. Zarrini G, Delgosha ZB, Moghaddam KM, Shahverdi AR 2010. Post- antibacterial effect of thymol. Pharm Biol 48: 633-636.
47. Zeromski J, Boczoń K, Wandurska-Nowak E, Mozer-Lisewska I 2005. Effect of aminoguanidine and albendazole on inducible nitric oxide synthase (iNOS) activity in T. spiralis-infected mice muscles. Folia Histochem Cytobiol 43: 157-159.