Development and validation of a multi-analyte LC-MS/MS approach for quantification of neuroleptics in whole blood, plasma, and serum

Drug Testing and Analysis

Volumn 8, Issue 10, 2016, Pages 1080-1089

  Montenarh, Deborah ^a   Hopf, Markus ^a   Maurer, Hans H ^a   Schmidt, Peter ^a   Ewald, Andreas H ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

LC MS MS; matrix effects; neuroleptics; validation

Indexed keywords

BLOOD; COPYRIGHTS; EFFICIENCY; EXTRACTION; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ALGEBRA; QUALITY CONTROL;

BLOOD SERUM; LC-MS-MS; LC.MS/MS; MATRICES EFFECT; MULTI-ANALYTES; NEUROLEPTIC; PROCESS EFFICIENCY; VALIDATION; WHOLE BLOOD; WHOLE BLOOD PLASMAS;

RECOVERY;

AMISULPRIDE; ARIPIPRAZOLE; ASENAPINE; BENPERIDOL; BROMPERIDOL; BUSPIRONE; CHLORPROMAZINE; CHLORPROTHIXENE; CLOZAPINE; DROPERIDOL; FLUPENTIXOL; FLUPHENAZINE; FLUSPIRILENE; HALOPERIDOL; LEVOMEPROMAZINE; MELPERONE; MOPERONE; NEUROLEPTIC AGENT; OLANZAPINE; PERAZINE; PERPHENAZINE; PIMOZIDE; PIPAMPERONE; PROMAZINE; PROMETHAZINE; PROTHIPENDYL; QUETIAPINE; RISPERIDONE; SERTINDOLE; UNINDEXED DRUG; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SCREENING; HUMAN; ISOTOPE LABELING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; NORMAL HUMAN; PRIORITY JOURNAL; QUALITY CONTROL; STABLE ISOTOPE LABELLED INTERNAL STANDARD; VALIDATION PROCESS; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLASMA; PROCEDURES; TANDEM MASS SPECTROMETRY;

ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LIMIT OF DETECTION; PLASMA; TANDEM MASS SPECTROMETRY;

EID: 84949571094     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1923     Document Type: Article

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