Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14

EMBO Journal

Volumn 34, Issue 22, 2015, Pages 2775-2788

  Fong, Jerry J ^a,b   Sreedhara, Karthik ^a,b   Deng, Liwen ^a   Varki, Nissi M ^a   Angata, Takashi ^c   Liu, Qinglian ^d   Nizet, Victor ^a,e   Varki, Ajit ^a,b,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

glycobiology; Hsp70; innate immunity; Siglec

Indexed keywords

HEAT SHOCK PROTEIN 70; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 14; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 5; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 7; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; DIFFERENTIATION ANTIGEN; LECTIN; LEUKOCYTE ANTIGEN; SIGLEC14 PROTEIN, HUMAN; SIGLEC5 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA POLYMORPHISM; EMBRYO; ENZYME ACTIVATION; GENE CONVERSION; GENE DELETION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MALE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL LINE, TUMOR; HEK293 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INFLAMMATION; LECTINS; MONOCYTES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 84949521619     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201591407     Document Type: Article

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