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Volumn 23, Issue 4, 2015, Pages 128-131

Choosing initial antiretroviral therapy: Current recommendations for initial therapy and newer or investigational agents

Author keywords

Antiretroviral drugs; BMS 663068; BMS 955176; Cabotegravir; CD4 attachment inhibitor; Doravirine; HIV; HIV maturation inhibitor; Initial therapy; TAF; Tenofovir

Indexed keywords

ABACAVIR; ABACAVIR PLUS DOLUTEGRAVIR PLUS LAMIVUDINE; ABACAVIR PLUS LAMIVUDINE; ANTIRETROVIRUS AGENT; ATAZANAVIR; BEVIRIMAT; BMS 955176; CABOTEGRAVIR; COBICISTAT; CYTOCHROME P450; DARUNAVIR; DARUNAVIR PLUS RITONAVIR; DOLUTEGRAVIR; DORAVIRINE; EFAVIRENZ; EMTRICITABINE; FOSTEMSAVIR; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; LAMIVUDINE; LOPINAVIR; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; PROTEINASE INHIBITOR; RALTEGRAVIR; RIFAMPICIN; RILPIVIRINE; RITONAVIR; RNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR ALAFENAMIDE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84949493908     PISSN: 21615861     EISSN: 21615853     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (25)
  • 1
    • 84901317078 scopus 로고    scopus 로고
    • Efficacy of initial antiretroviral therapy for HIV-1 infection in adults: A systematic review and meta-analysis of 114 studies with up to 144 weeks' follow-up
    • Lee FJ, Amin J, Carr A. Efficacy of initial antiretroviral therapy for HIV-1 infection in adults: a systematic review and meta-analysis of 114 studies with up to 144 weeks' follow-up. PLoS One. 2014; 9(5):e97482.
    • (2014) Plos One , vol.9 , Issue.5
    • Lee, F.J.1    Amin, J.2    Carr, A.3
  • 2
    • 84887052771 scopus 로고    scopus 로고
    • Dolutegravir plus abacavir-lamivudine for the treatment of HIV-1 infection
    • Walmsley SL, Antela A, Clumeck N, et al. Dolutegravir plus abacavir-lamivudine for the treatment of HIV-1 infection. N Engl J Med. 2013;369(19): 1807-1818.
    • (2013) N Engl J Med , vol.369 , Issue.19 , pp. 1807-1818
    • Walmsley, S.L.1    Antela, A.2    Clumeck, N.3
  • 3
    • 84903303497 scopus 로고    scopus 로고
    • Once-daily dolutegravir versus darunavir plus ritonavir in antiretroviral-naive adults with HIV-1 infection (FLAMINGO): 48 week results from the randomized open-label phase 3b study
    • Clotet B, Feinberg J, van Lunzen J, et al. Once-daily dolutegravir versus darunavir plus ritonavir in antiretroviral-naive adults with HIV-1 infection (FLAMINGO): 48 week results from the randomized open-label phase 3b study. Lancet. 2014;383(9936):2222-2231.
    • (2014) Lancet , vol.383 , Issue.9936 , pp. 2222-2231
    • Clotet, B.1    Feinberg, J.2    Van Lunzen, J.3
  • 4
    • 84908086389 scopus 로고    scopus 로고
    • Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: A randomized, controlled equivalence trial
    • Lennox JL, Landovitz RJ, Ribaudo HJ, et al. Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial. Ann Intern Med. 2014;161(7):461-471.
    • (2014) Ann Intern Med , vol.161 , Issue.7 , pp. 461-471
    • Lennox, J.L.1    Landovitz, R.J.2    Ribaudo, H.J.3
  • 5
    • 84937215233 scopus 로고    scopus 로고
    • Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: Two randomised, double-blind, phase 3, non-inferiority trials
    • Sax PE, Wohl D, Yin MT, et al. Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials. Lancet. 2015;385(9987):2606-2615.
    • (2015) Lancet , vol.385 , Issue.9987 , pp. 2606-2615
    • Sax, P.E.1    Wohl, D.2    Yin, M.T.3
  • 6
    • 72049086981 scopus 로고    scopus 로고
    • Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection
    • Gill VS, Lima VD, Zhang W, et al. Improved virological outcomes in British Columbia concomitant with decreasing incidence of HIV type 1 drug resistance detection. Clin Infect Dis. 2010;50(1):98-105.
    • (2010) Clin Infect Dis , vol.50 , Issue.1 , pp. 98-105
    • Gill, V.S.1    Lima, V.D.2    Zhang, W.3
  • 7
    • 84904568743 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society–USA panel
    • Günthard HF, Aberg JA, Eron JJ, et al. Antiretroviral treatment of adult HIV infection: 2014 recommendations of the International Antiviral Society–USA panel. JAMA. 2014;312(4):410-425.
    • (2014) JAMA , vol.312 , Issue.4 , pp. 410-425
    • Günthard, H.F.1    Aberg, J.A.2    Eron, J.J.3
  • 12
    • 84874411899 scopus 로고    scopus 로고
    • Once-daily dolutegravir versus raltegravir in antiretroviral-naive adults with HIV-1 infection: 48 week results from the randomised, double-blind, non-inferiority SPRING-2 study
    • Raffi F, Rachlis A, Stellbrink HJ, et al. Once-daily dolutegravir versus raltegravir in antiretroviral-naive adults with HIV-1 infection: 48 week results from the randomised, double-blind, non-inferiority SPRING-2 study. Lancet. 2013;381(9868):735-743.
    • (2013) Lancet , vol.381 , Issue.9868 , pp. 735-743
    • Raffi, F.1    Rachlis, A.2    Stellbrink, H.J.3
  • 14
    • 84896855316 scopus 로고    scopus 로고
    • In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor
    • Lai MT, Feng M, Falgueyret JP, et al. In vitro characterization of MK-1439, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2014;58(3):1652-1663.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.3 , pp. 1652-1663
    • Lai, M.T.1    Feng, M.2    Falgueyret, J.P.3
  • 15
    • 85018217254 scopus 로고    scopus 로고
    • The effect of single and multiple dose rifampin on the pharmacokinetics of doravirine [CROI abstract 521]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections
    • Yee KL, Khalilieh SG, Liu R, et al. The effect of single and multiple dose rifampin on the pharmacokinetics of doravirine [CROI abstract 521]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2015; 23(e-1):217.
    • (2015) Top Antivir Med , vol.23 , Issue.1 , pp. 217
    • Yee, K.L.1    Khalilieh, S.G.2    Liu, R.3
  • 16
    • 84947550674 scopus 로고    scopus 로고
    • Safety, tolerability and pharmacokinetics of doravirine, a novel HIV non-nucleoside reverse transcriptase inhibitor, after single and multiple doses in healthy subjects
    • Anderson MS, Gilmartin J, Cilissen C, et al. Safety, tolerability and pharmacokinetics of doravirine, a novel HIV non-nucleoside reverse transcriptase inhibitor, after single and multiple doses in healthy subjects. Antivir Ther. 2014;20(4):397-405.
    • (2014) Antivir Ther , vol.20 , Issue.4 , pp. 397-405
    • Anderson, M.S.1    Gilmartin, J.2    Cilissen, C.3
  • 17
    • 85018219786 scopus 로고    scopus 로고
    • A randomized, doubleblind, placebo-controlled, short-term monotherapy study of doravirine in treatment-naive HIV-infected patients
    • Schurmann D, Sobotha C, Gilmartin J, et al. A randomized, doubleblind, placebo-controlled, short-term monotherapy study of doravirine in treatment-naive HIV-infected patients. AIDS. 2015; [Epub ahead of print].
    • (2015) AIDS
    • Schurmann, D.1    Sobotha, C.2    Gilmartin, J.3
  • 18
    • 85018220586 scopus 로고    scopus 로고
    • Safety and antiviral effect of MK-1439, a novel NNRTI (+FTC/TDF) in ART-naive HIVinfected patients [CROI Abstract 92LB]. In Special Issue: Abstracts From the 2014 Conference on Retroviruses and Opportunistic Infections
    • Morales-Ramirez JO, Gatell JM, Hagins DP, et al. Safety and antiviral effect of MK-1439, a novel NNRTI (+FTC/TDF) in ART-naive HIVinfected patients [CROI Abstract 92LB]. In Special Issue: Abstracts From the 2014 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2014;22(e-1):46-47.
    • (2014) Top Antivir Med , vol.22 , Issue.1 , pp. 46-47
    • Morales-Ramirez, J.O.1    Gatell, J.M.2    Hagins, D.P.3
  • 19
    • 84969378771 scopus 로고    scopus 로고
    • Forty-eight-week efficacy and safety and early CNS tolerability of doravirine (MK-1439), a novel NNRTI, with TDF/FTC in ART-naive HIV-positive patients
    • Gatell JM, Morales-Ramirez JO, Hagins DP, et al. Forty-eight-week efficacy and safety and early CNS tolerability of doravirine (MK-1439), a novel NNRTI, with TDF/FTC in ART-naive HIV-positive patients. J Int AIDS Soc. 2014;17(4 Suppl 3):19532.
    • (2014) J Int AIDS Soc , vol.17 , pp. 19532
    • Gatell, J.M.1    Morales-Ramirez, J.O.2    Hagins, D.P.3
  • 20
    • 84925557632 scopus 로고    scopus 로고
    • GSK1265744 pharmacokinetics in plasma and tissue after single-dose long-acting injectable administration in healthy subjects
    • Spreen W, Ford SL, Chen S, et al. GSK1265744 pharmacokinetics in plasma and tissue after single-dose long-acting injectable administration in healthy subjects. JAIDS 2014;67(5):481-486.
    • (2014) JAIDS , vol.67 , Issue.5 , pp. 481-486
    • Spreen, W.1    Ford, S.L.2    Chen, S.3
  • 21
    • 84942191100 scopus 로고    scopus 로고
    • Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): A randomised, phase 2b, dose-ranging trial
    • Margolis DA, Brinson CC, Smith GH, et al. Cabotegravir plus rilpivirine, once a day, after induction with cabotegravir plus nucleoside reverse transcriptase inhibitors in antiretroviral-naive adults with HIV-1 infection (LATTE): a randomised, phase 2b, dose-ranging trial. Lancet Infect Dis. 2015;15(10):1145-1155.
    • (2015) Lancet Infect Dis , vol.15 , Issue.10 , pp. 1145-1155
    • Margolis, D.A.1    Brinson, C.C.2    Smith, G.H.3
  • 22
    • 84866124136 scopus 로고    scopus 로고
    • Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects
    • Nettles RE, Schurmann D, Zhu L, et al. Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects. J Infect Dis. 2012;206(7):1002-1011.
    • (2012) J Infect Dis , vol.206 , Issue.7 , pp. 1002-1011
    • Nettles, R.E.1    Schurmann, D.2    Zhu, L.3
  • 23
    • 85018215969 scopus 로고    scopus 로고
    • Attachment inhibitor prodrug BMS-663068 in ARV-experienced subjects: Week 48 analysis [CROI abstract 545]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections
    • Thompson M, Lalezari J, Kaplan R, et al. Attachment inhibitor prodrug BMS-663068 in ARV-experienced subjects: week 48 analysis [CROI abstract 545]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2015;23(e-1):227-228.
    • (2015) Top Antivir Med , vol.23 , Issue.1 , pp. 227-228
    • Thompson, M.1    Lalezari, J.2    Kaplan, R.3
  • 24
    • 85018221831 scopus 로고    scopus 로고
    • HIV-1 attachment inhibitor prodrug BMS-663068: Model-based dose selection [CROI abstract 509]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections
    • Landry IS, Zhu L, Abutarif M, et al. HIV-1 attachment inhibitor prodrug BMS-663068: model-based dose selection [CROI abstract 509]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2015;23 (e-1):211.
    • (2015) Top Antivir Med , vol.23 , Issue.1 , pp. 211
    • Landry, I.S.1    Zhu, L.2    Abutarif, M.3
  • 25
    • 85018218742 scopus 로고    scopus 로고
    • Antiviral activity/safety of a second-generation HIV-1 maturation inhibitor [CROI abstract 114LB]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections
    • Hwang C, Schurmann D, Sobotha C, et al. Antiviral activity/safety of a second-generation HIV-1 maturation inhibitor [CROI abstract 114LB]. In Special Issue: Abstracts From the 2015 Conference on Retroviruses and Opportunistic Infections. Top Antivir Med. 2015; 23(e-1):48.
    • (2015) Top Antivir Med , vol.23 , Issue.1 , pp. 48
    • Hwang, C.1    Schurmann, D.2    Sobotha, C.3


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