A mouse model of subchronic and mild social defeat stress for understanding stress-induced behavioral and physiological deficits

Journal of Visualized Experiments

Volumn 2015, Issue 105, 2015, Pages

  Goto, Tatsuhiko ^a   Toyoda, Atsushi ^a,b  

^a IBARAKI UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

Animal model; Behavior; Chronic social defeat stress; Issue 105; Mouse; Neuroscience; Polydipsia; Purified diet; Social behavior; Weight gain

Indexed keywords

EID: 84949448835     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/52973     Document Type: Article

References (32)

1. Heim, C., & Binder, E. B. Current research trends in early life stress and depression: Review of human studies on sensitive periods, geneenvironment interactions, and epigenetics. Exp. Neurol. 233 (1), 102-111 (2012).
2. Whiteford, H.A., et al. Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet. 382 (9904), 1575-1586 (2013).
3. Ferrari, A. J., et al. The Burden Attributable to Mental and Substance Use Disorders as Risk Factors for Suicide: Findings from the Global Burden of Disease Study 2010. PLoS ONE. 9 (4), e91936 (2014).
4. Flint, J., & Kendler, K. S. The genetics of major depression. Neuron. 81 (3), 484-503 (2014).
5. Nestler, E. J., et al. Neurobiology of Depression. Neuron. 34 (1), 13-25 (2002).
6. Gold, P. W., & Chrousos, G. P. Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states. Mol. Psychiatry. 7 (3), 254-275 (2002).
7. O'Keane, V., Frodl, T., & Dinan, T. G. A review of atypical depression in relation to the course of depression and changes in HPA axis organization. Psychoneuroendocrinology. 37 (10), 1589-1599 (2012).
8. Nestler, E. J., & Hyman, S. E. Animal models of neuropsychiatric disorders. Nat. Neurosci. 13 (10), 1161-1169 (2010).
9. Katz, R. J. Animal models and human depressive disorders. Neurosci. Biobehav. Rev. 5 (2), 231-246 (1981).
10. Krishnan, V., & Nestler, E. J. Animal models of depression: molecular perspectives. Curr. Top. Behav. Neurosci. 7, 121-147 (2011).
11. Kudryavtseva, N. N., Bakshtanovskaya, I. V., & Koryakina, L. A. Social model of depression in mice of C57BL/6J strain. Pharmacol. Biochem. Behav. 38 (2), 315-320 (1991).
12. Miczek, K. A., Yap, J. J., & Covington, H. E.3rd. Social stress, therapeutics and drug abuse: preclinical models of escalated and depressed intake. Pharmacol. Ther. 120 (2), 102-128 (2008).
13. Goto, T., et al. Subchronic and mild social defeat stress accelerates food intake and body weight gain with polydipsia-like features in mice. Behav. Brain Res. 270, 339-348 (2014).
14. Goto, T., Kubota, Y., & Toyoda, A. Plasma and Liver Metabolic Profiles in Mice Subjected to Subchronic and Mild Social Defeat Stress. J. Proteome Res. (2014).
15. Iio, W., Matsukawa, N., Tsukahara, T., Kohari, D., & Toyoda, A. Effects of chronic social defeat stress on MAP kinase cascade. Neurosci. Lett. 504 (3), 281-284 (2011).
16. Iio, W., et al. Effects of chronic social defeat stress on peripheral leptin and its hypothalamic actions. BMC Neurosci. 15, 72 (2014).
17. Iio, W., et al. Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. Biochem. Biophys. Res. Commun. 421 (2), 301-304 (2012).
18. Crawley, J. N. What's Wrong With My Mouse?: Behavioral Phenotyping of Transgenic and Knockout Mice. 2nd ed. Hoboken, John Wiley & Sons Inc, ISBN: 978-0-471-47192-9 (2007).
19. Golden, S. A., Covington, H. E. 3rd., Berton, O., & Russo, S. J. A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 6 (8), 1183-1191 (2011).
20. Miczek, K. A., Maxson, S. C., Fish, E. W., & Faccidomo S. Aggressive behavioral phenotypes in mice. Behav. Brain Res. 125, 167-181 (2001).
21. Krishnan, V., et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell. 131 (2), 391- 404 (2007).
22. Chuang, J.C., et al. A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biol. Psychiatry. 67 (11), 1075-1082 (2010).
23. Warren, B.L., et al. Neurobiological sequelae of witnessing stressful events in adult mice. Biol. Psychiatry. 73 (1), 7-14 (2013).
24. Savignac, H.M., et al. Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain. Neuroscience. 192, 524-536 (2011).
25. Green, J.G., et al. Childhood Adversities and Adult Psychiatric Disorders in the National Comorbidity Survey Replication I: associations with first onset of DSM-IV disorders. Arch. Gen. Psychiatry. 67 (2), 113-123 (2010).
26. Miniati, M., et al. Clinical characteristics and treatment outcome of depression in patients with and without a history of emotional and physical abuse. J. Psychiatr. Res. 44 (5), 302-309 (2010).
27. Tao, M., et al. Examining the relationship between lifetime stressful life events and the onset of major depression in Chinese women. J. Affect. Disord. 135 (1-3), 95-99 (2011).
28. Valente, S., & Fisher, D. Recognizing and managing psychogenic polydipsia in mental health. J. Nurse Pract. 6 (7), 546-550 (2010).
29. Dundas, B., & Harris, M., Narasimham, M. Psychogenic Polydipsia Review: Etiology, Differential, and Treatment. Curr. Psychiatry Rep. 9 (3), 236-241 (2007).
30. Tsumura, K., et al. Downregulation of AQP2 expression in the kidney of polydipsic STR/N mice. Am. J. Physiol. Renal Physiol. 290 (2), F478- F485 (2006).
31. Flores, P., et al. Schedule-Induced Polydipsia: Searching for the Endophenotype of Compulsive Behavior. World J. Neurosci. 4, 253-260 (2014).
32. Cryan, J. F., & Dinan, T. G. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat. Rev. Neurosci. 13 (10), 701-712 (2012).