Early allograft dysfunction after liver transplantation: An intermediate outcome measure for targeted improvements

Annals of Hepatology

Volumn 15, Issue 1, 2016, Pages 53-60

  Lee, David D ^a   Croome, Kristopher P ^a   Shalev, Jefree A ^a   Musto, Kaitlyn R ^a   Sharma, Meenu ^a   Keaveny, Andrew P ^a   Taner, C Burcin ^a  

^a Department of Transplant   (United States)

Author keywords

Liver transplantation; Outcome; Survival

Indexed keywords

BILIRUBIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER;

ADULT; AGE; ARTICLE; CONTROLLED STUDY; EARLY ALLOGRAFT DYSFUNCTION; FEMALE; GRAFT DYSFUNCTION; HEART DEATH; HUMAN; INTERNATIONAL NORMALIZED RATIO; LENGTH OF STAY; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OPERATION DURATION; ORGAN DONOR; ORGAN SIZE; PEROPERATIVE CARE; PREOPERATIVE CARE; RISK FACTOR; STEATOSIS; SURVIVAL; TREATMENT OUTCOME; ADOLESCENT; ADVERSE EFFECTS; AGED; ALLOGRAFT; BLOOD; CHI SQUARE DISTRIBUTION; CHILD; ENZYME ASSAY; EPIDEMIOLOGY; FLORIDA; GRAFT SURVIVAL; HEALTH CARE QUALITY; INCIDENCE; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE; PRESCHOOL CHILD; PRIMARY GRAFT DYSFUNCTION; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; TIME FACTOR; TOTAL QUALITY MANAGEMENT; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ALLOGRAFTS; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; BIOMARKERS; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; CLINICAL ENZYME TESTS; FEMALE; FLORIDA; GRAFT SURVIVAL; HUMANS; INCIDENCE; INTERNATIONAL NORMALIZED RATIO; KAPLAN-MEIER ESTIMATE; LENGTH OF STAY; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PRIMARY GRAFT DYSFUNCTION; PROPORTIONAL HAZARDS MODELS; QUALITY IMPROVEMENT; QUALITY INDICATORS, HEALTH CARE; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84949188932     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.5604/16652681.1184212     Document Type: Article

References (26)

1. Deschênes M, Belle SH, Krom RA, Zetterman RK, Lake JR. Early allograft dysfunction after liver transplantation: a definition and predictors of outcome. National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database. Transplantation 1998; 66: 302-10.
2. Olthoff KM, Kulik L, Samstein B, Kaminski M, Abecassis M, Emond J, Shaked A, et al. Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors. Liver Transplantation 2010; 16: 943-9.
3. Croome KP, Hernandez-Alejandro R, Chandok N. Early allograft dysfunction is associated with excess resource utilization after liver transplantation. Transplant Proceedings 2013; 45: 259-64.
4. Camci C, Akdogan M, Gurakar A, Gilcher R, Rose J, Monlux R, Alamain S, et al. The impact of total plasma exchange on early allograft dysfunction. Transplant Proceedings 2004; 36: 2567-9.
5. Deschenes M. Early allograft dysfunction: causes, recognition, and management. Liver Transplantation 2013; 19: S6-S8.
6. Friedman BH, Wolf JH, Wang L, Putt ME, Shaked A, Christie JD, Hancock WW, et al. Serum cytokine profiles associated with early allograft dysfunction in patients undergoing liver transplantation. Liver Transplantation 2012; 18: 166-76.
7. Hoyer DP, Paul A, Gallinat EP, Reinhardt R, Minor T, Saner FH, Canbay A, et al. Donor information based prediction of early allograft dysfunction and outcome in liver transplantation. Liver International 2015; 35: 156-63.
8. Cortes M, Pareja E, García-Canaveras JC, Donato MT, Montero S, Mir J, Castel JV, et al. Metabolomics, discloses donor liver biomarkers associated with early allograft dysfunction. J Hepatology 2014; 61: 564-74.
9. Taner CB, Bulatao IG, Willingham DL, Perry DK, Sibulesky L, Pungpapong S, Aranda-Michel J, et al. Events in procurement as risk factors for ischemic cholangiopathy in liver transplantation using donation after cardiac death donors. Liver Transplantation 2012; 18: 100-11.
10. Feng S, Goodrich NP, Bragg-Gresham JL, Dykstra DM, Punch JD, DebRoy MA, Greenstein SM, et al. Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant 2006; 6: 783-90.
11. Ploeg RJ, D’Alessandro AM, Knechtle SJ, Stegall MD, Pirsch JD, Hoffmann RM, Saaki T, et al. Risk factors for primary dysfunction after liver transplantation-a multivariate analysis. Transplantation 1993; 55: 807-13.
12. Hong JC, Kaldas FM, Kositamongkol P, Petrowsky H, Farmer DG, Markovic D, Hiatt JR, et al. Predictive index for long-term survival after retransplantation of the liver in adult recipients: analysis of a 26-year experience in a single center. Ann Surg 2011; 254: 444-8.
13. Salvalaggio PR, Felga GE, Afonso RC, Ferraz-Neto BH. Early allograft dysfunction and liver transplant outcomes: a single center retrospective study. Transplant Proceedings 2012; 44(8): 2449-51.
14. Wagener G, Raffel B, Young AT, Minhaz M, Emond J. Predicting early allograft failure and mortality after liver transplantation: the role of the postoperative model for end-stage liver disease score. Liver Transplantation 2013; 19: 534-42.
15. Hong SH, Kwak JA, Jeon JY, Park CS. Prediction of early allograft dysfunction using serum phosphorous level in living donor liver transplantation. Transplant International 2013; 26: 402-10.
16. McDiarmid SV, Anand R, Martz K, Milis MJ, Mazariegos G. A multivariate analysis of Pre-, Peri-, and Post-transplant factors affecting outcome after pediatric liver transplantation. Ann Surg 2011; 254: 145-54.
17. Friedman BH, Wolf JH, Wang L, Putt ME, Shaked A, Christie JD, Hancock WW, et al. Serum cytokine profiles associated with early allograft dysfunction in patients undergoing liver transplantation. Liver Transplantation 2012; 18: 166-76.
18. Guarrera JV, Henry SD, Samstein B, Reznik E, Musat C, Lukose TI, Ratner LE, et al. Hypothermic machine preservation facilitates successful transplantation of “orphan” extended criteria donor livers. Am J Transplant 2015; 15: 161-9.
19. Vogel T, Brockmann JG, Coussios C, Friend PJ. The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury. Transplant Reviews (Orlando) 2012; 26: 156-62.
20. Jamieson RW, Zilvetti M, Roy D, Hughes D, Morovat A, Coussios CC, Friend PJ. Hepatic steatosis and normothermic perfusion-preliminary experiments in a porcine model. Transplantation 2011; 92: 289-95.
21. Lee DD, Singh A, Burns JM, Perry DK, Nguyen JH, Taner CB. Early allograft dysfunction in liver transplantation using donation after cardiac death donors results in inferior survival. Liver Transplantation 2014; 20: 1447-53.
22. Saidi RF, Bradley J, Greer D, Luskin R, O’Connor K, Delmonico F, Kennealey P, et al. Changing Pattern of Organ Donation at a Single Center: Are Potential Brain Dead Donors Being Lost to Donation After Cardiac Death? Am J Transplant 2010; 10: 2536-40.
23. Biancofiore G, Bindi ML, Romanelli AM, Bisà M, Boldrini A, Consani G, Filipponi F, et al. Postoperative intra-abdominal pressure and renal function after liver transplantation. Arch Surg 2003; 7: 703-6.
24. Lai JC, Feng S, Roberts JP. An examination of liver offers to candidates on the liver transplant wait-list. Gastroenterology 2012; 143: 1261-5.
25. Barshes NR, Horwitz IB, Franzini L, Vierling JM, Goss JA. Waitlist mortality decreases with increased use of extended criteria donor liver grafts at adult liver transplant centers. Am J Transplant 2007; 7: 1265-70.
26. Ghaferi AA, Birkmeyer JD, Dimick JB. Variation in hospital mortality associated with inpatient surgery. N Eng J Med 2009; 361: 1368-75.