Clinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both

Leukemia and Lymphoma

Volumn 56, Issue 12, 2015, Pages 3357-3364

  Zand, Ladan ^a   Nasr, Samih H ^b   Gertz, Morie A ^c   Dispenzieri, Angela ^c   Lacy, Martha Q ^c   Buadi, Francis K ^c   Kumar, Shaji ^c   Kyle, Robert A ^c   Fervenza, Fernando C ^a   Sethi, Sanjeev ^b   Dingli, David ^b   Rajkumar, S Vincent ^b   Kapoor, Prashant ^c   McCurdy, Arleigh ^c   Leung, Nelson ^a,c  

^a Division of Nephrology and Hypertension   (United States)

^b Department of Laboratory Medicine and Pathology ^*  (United States)

^c MAYO CLINIC   (United States)

Author keywords

Light chain deposition disease; multiple myeloma; myeloma cast nephropathy; renal disease

Indexed keywords

CREATININE; IMMUNOGLOBULIN LIGHT CHAIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; BONE ATROPHY; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; FEMALE; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; KIDNEY DISEASE; LIGHT CHAIN DEPOSITION DISEASE; MAJOR CLINICAL STUDY; MALE; MYELOMA; MYELOMA CAST NEPHROPATHY; OVERALL SURVIVAL; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; RETROSPECTIVE STUDY; AMYLOID NEUROPATHIES; BIOPSY; COMPLICATION; FLUORESCENCE MICROSCOPY; KIDNEY; KIDNEY DISEASES; KIDNEY DISTAL TUBULE; METABOLISM; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; MULTIPLE MYELOMA; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; TREATMENT OUTCOME; ULTRASTRUCTURE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AMYLOID NEUROPATHIES; BIOPSY; COMBINED MODALITY THERAPY; FEMALE; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; KIDNEY; KIDNEY DISEASES; KIDNEY TUBULES, DISTAL; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MULTIPLE MYELOMA; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84948673433     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2015.1040011     Document Type: Article

References (12)

1. Randall RE, Williamson WC Jr, Mullinax F, et al. Manifestations of systemic light chain deposition. Am J Med 1976; 60: 293-299.
2. Nasr SH, Valeri AM, Cornell LD, et al. Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institution. Clin J Am Soc Nephrol 2012; 7: 231-239.
3. Heilman RL, Velosa JA, Holley KE, et al. Long-term follow-up and response to chemotherapy in patients with light-chain deposition disease. Am J Kidney Dis 1992; 20: 34-41.
4. Lin J, Markowitz GS, Valeri AM, et al. Renal monoclonal immunoglobulin deposition disease: the disease spectrum. J Am Soc Nephrol 2001; 12: 1482-1492.
5. Ronco PM, Alyanakian MA, Mougenot B, et al. Light chain deposition disease: a model of glomerulosclerosis defined at the molecular level. J Am Soc Nephrol 2001; 12: 1558-1565.
6. Pozzi C, DAmico M, Fogazzi GB, et al. Light chain deposition disease with renal involvement: clinical characteristics and prognostic factors. Am J Kidney Dis 2003; 42: 1154-1163.
7. Buxbaum JN, Chuba JV, Hellman GC, et al. Monoclonal immunoglobulin deposition disease: light chain and light and heavy chain deposition diseases and their relation to light chain amyloidosis. Clinical features, immunopathology, and molecular analysis. Ann Internal Med 1990; 112: 455-464.
8. Leung N, Bridoux F, Hutchison CA, et al. Monoclonal gammopathy of renal significance: when MGUS is no longer undetermined or insignificant. Blood 2012; 120: 4292-4295.
9. Ganeval D, Noel LH, Preud'homme JL, et al. Light-chain deposition disease: its relation with AL-type amyloidosis. Kidney Int 1984; 26: 1-9.
10. Tubbs RR, Gephardt GN, McMahon JT, et al. Light chain nephropathy. Am J Med 1981; 71: 263-269.
11. Ronco P, Plaisier E, Mougenot B, et al. Immunoglobulin light (heavy)-chain deposition disease: from molecular medicine to pathophysiology-driven therapy. Clin J Am Soc Nephrol 2006; 1: 1342-1350.
12. Buxbaum J, Gallo G. Nonamyloidotic monoclonal immunoglobulin deposition disease. Light-chain, heavy-chain, and light-and heavy-chain deposition diseases. Hematol/oncol Clin North Am 1999; 13: 1235-1248.