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Volumn 121, Issue 23, 2015, Pages 4141-4149

Addition of radiotherapy to adjuvant chemotherapy is associated with improved overall survival in resected pancreatic adenocarcinoma: An analysis of the National Cancer Data Base

Author keywords

chemoradiation; chemotherapy; pancreatic; radiation

Indexed keywords

ARTICLE; CANCER ADJUVANT THERAPY; CANCER CLASSIFICATION; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CLINICAL FEATURE; COHORT ANALYSIS; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; PRIORITY JOURNAL; RADIATION DOSE; TREATMENT OUTCOME; ADENOCARCINOMA; ADJUVANT CHEMORADIOTHERAPY; ADJUVANT CHEMOTHERAPY; ADULT; AGED; FACTUAL DATABASE; MIDDLE AGED; MORTALITY; PANCREATIC NEOPLASMS; PATHOLOGY; PROPENSITY SCORE; PROPORTIONAL HAZARDS MODEL; SURVIVAL; VERY ELDERLY;

EID: 84948585742     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.29652     Document Type: Article
Times cited : (69)

References (34)
  • 1
    • 84960126081 scopus 로고    scopus 로고
    • National Cancer Institute. Accessed February 9
    • National Cancer Institute. SEER Stat Fact Sheets: Pancreas Cancer. http://seer.cancer.gov/statfacts/html/pancreas.html. Accessed February 9, 2015.
    • (2015) SEER Stat Fact Sheets: Pancreas Cancer.
  • 2
    • 33846405332 scopus 로고    scopus 로고
    • Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial
    • Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA. 2007;297:267-277.
    • (2007) JAMA. , vol.297 , pp. 267-277
    • Oettle, H.1    Post, S.2    Neuhaus, P.3
  • 3
    • 12144287320 scopus 로고    scopus 로고
    • A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
    • Neoptolemos JP, Stocken DD, Friess H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004;350:1200-1210.
    • (2004) N Engl J Med. , vol.350 , pp. 1200-1210
    • Neoptolemos, J.P.1    Stocken, D.D.2    Friess, H.3
  • 4
    • 77952090720 scopus 로고    scopus 로고
    • Adjuvant chemoradiation for pancreatic adenocarcinoma: The Johns Hopkins Hospital-Mayo Clinic collaborative study
    • Hsu CC, Herman JM, Corsini MM, et al. Adjuvant chemoradiation for pancreatic adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study. Ann Surg Oncol. 2010;17:981-990.
    • (2010) Ann Surg Oncol. , vol.17 , pp. 981-990
    • Hsu, C.C.1    Herman, J.M.2    Corsini, M.M.3
  • 6
    • 78049434513 scopus 로고    scopus 로고
    • Adjuvant gemcitabine alone versus gemcitabine-based chemoradiotherapy after curative resection for pancreatic cancer: A randomized EORTC-40013-22012/FFCD-9203/GERCOR phase II study
    • Van Laethem JL, Hammel P, Mornex F, et al. Adjuvant gemcitabine alone versus gemcitabine-based chemoradiotherapy after curative resection for pancreatic cancer: a randomized EORTC-40013-22012/FFCD-9203/GERCOR phase II study. J Clin Oncol. 2010; 28:4450-4456.
    • (2010) J Clin Oncol. , vol.28 , pp. 4450-4456
    • Van Laethem, J.L.1    Hammel, P.2    Mornex, F.3
  • 7
    • 62249176551 scopus 로고    scopus 로고
    • DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
    • Iacobuzio-Donahue CA, Fu B, Yachida S, et al. DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer. J Clin Oncol. 2009;27:1806-1813.
    • (2009) J Clin Oncol. , vol.27 , pp. 1806-1813
    • Iacobuzio-Donahue, C.A.1    Fu, B.2    Yachida, S.3
  • 9
    • 0023262033 scopus 로고
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer
    • Gastrointestinal Tumor Study Group.
    • Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer. 1987;59:2006-2010.
    • (1987) Cancer. , vol.59 , pp. 2006-2010
  • 10
    • 0033497862 scopus 로고    scopus 로고
    • Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: Phase III trial of the EORTC Gastrointestinal Tract Cancer Cooperative Group
    • Klinkenbijl JH, Jeekel J, Sahmoud T, et al. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC Gastrointestinal Tract Cancer Cooperative Group. Ann Surg. 1999;230: 776-782.
    • (1999) Ann Surg. , vol.230 , pp. 776-782
    • Klinkenbijl, J.H.1    Jeekel, J.2    Sahmoud, T.3
  • 11
    • 40449113435 scopus 로고    scopus 로고
    • Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: A randomized controlled trial
    • Regine WF, Winter KA, Abrams RA, et al. Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA. 2008;299:1019-1026.
    • (2008) JAMA. , vol.299 , pp. 1019-1026
    • Regine, W.F.1    Winter, K.A.2    Abrams, R.A.3
  • 12
    • 77952319560 scopus 로고    scopus 로고
    • The role of radiation therapy in pancreas cancer
    • Hazard L. The role of radiation therapy in pancreas cancer. Gastrointest Cancer Res. 2009;3:20-28.
    • (2009) Gastrointest Cancer Res. , vol.3 , pp. 20-28
    • Hazard, L.1
  • 13
    • 84861618476 scopus 로고    scopus 로고
    • Analysis of local control in patients receiving IMRT for resected pancreatic cancers
    • Yovino S, Maidment BW III, Herman JM, et al. Analysis of local control in patients receiving IMRT for resected pancreatic cancers. Int J Radiat Oncol Biol Phys. 2012;83:916-920.
    • (2012) Int J Radiat Oncol Biol Phys. , vol.83 , pp. 916-920
    • Yovino, S.1    Maidment, B.W.2    Herman, J.M.3
  • 14
    • 84855827439 scopus 로고    scopus 로고
    • Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704-A phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas
    • Abrams RA, Winter KA, Regine WF, et al. Failure to adhere to protocol specified radiation therapy guidelines was associated with decreased survival in RTOG 9704-A phase III trial of adjuvant chemotherapy and chemoradiotherapy for patients with resected adenocarcinoma of the pancreas. Int J Radiat Oncol Biol Phys. 2012;82: 809-816.
    • (2012) Int J Radiat Oncol Biol Phys. , vol.82 , pp. 809-816
    • Abrams, R.A.1    Winter, K.A.2    Regine, W.F.3
  • 15
    • 79955921754 scopus 로고    scopus 로고
    • Folfirinox versus gemcitabine for metastatic pancreatic cancer
    • Conroy T, Desseigne F, Ychou M, et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med. 2011;364: 1817-1825.
    • (2011) N Engl J Med. , vol.364 , pp. 1817-1825
    • Conroy, T.1    Desseigne, F.2    Ychou, M.3
  • 16
    • 84866731260 scopus 로고    scopus 로고
    • Five year results of US intergroup/RTOG 9704 with postoperative CA 19-9-90 U/mL and comparison to the CONKO-001 trial
    • Berger AC, Winter K, Hoffman JP, et al. Five year results of US intergroup/RTOG 9704 with postoperative CA 19-9-90 U/mL and comparison to the CONKO-001 trial. Int J Radiat Oncol Biol Phys. 2012;84:e291-e297.
    • (2012) Int J Radiat Oncol Biol Phys. , vol.84 , pp. e291-e297
    • Berger, A.C.1    Winter, K.2    Hoffman, J.P.3
  • 17
    • 55249091643 scopus 로고    scopus 로고
    • The impact of resection margin status and postoperative CA19-9 levels on survival and patterns of recurrence after postoperative high-dose radiotherapy with 5-FU-based concurrent chemotherapy for resectable pancreatic cancer
    • Kinsella TJ, Seo Y, Willis J, et al. The impact of resection margin status and postoperative CA19-9 levels on survival and patterns of recurrence after postoperative high-dose radiotherapy with 5-FU-based concurrent chemotherapy for resectable pancreatic cancer. Am J Clin Oncol. 2008;31:446-453.
    • (2008) Am J Clin Oncol. , vol.31 , pp. 446-453
    • Kinsella, T.J.1    Seo, Y.2    Willis, J.3
  • 18
    • 84863625926 scopus 로고    scopus 로고
    • Immortal time bias: A frequently unrecognized threat to validity in the evaluation of postoperative radiotherapy
    • Park HS, Gross CP, Makarov DV, Yu JB. Immortal time bias: a frequently unrecognized threat to validity in the evaluation of postoperative radiotherapy. Int J Radiat Oncol Biol Phys. 2012;83:1365-1373.
    • (2012) Int J Radiat Oncol Biol Phys. , vol.83 , pp. 1365-1373
    • Park, H.S.1    Gross, C.P.2    Makarov, D.V.3    Yu, J.B.4
  • 19
    • 84869456305 scopus 로고    scopus 로고
    • Keys to personalized care in pancreatic oncology
    • Crane CH, Iacobuzio-Donahue CA. Keys to personalized care in pancreatic oncology. J Clin Oncol. 2012;30:4049-4950.
    • (2012) J Clin Oncol. , vol.30 , pp. 4049-4950
    • Crane, C.H.1    Iacobuzio-Donahue, C.A.2
  • 20
    • 84910119746 scopus 로고    scopus 로고
    • Effect of adjuvant radiotherapy on survival in resected pancreatic cancer: A propensity score Surveillance, Epidemiology, and End Results database analysis
    • Sugawara A, Kunieda E. Effect of adjuvant radiotherapy on survival in resected pancreatic cancer: a propensity score Surveillance, Epidemiology, and End Results database analysis. J Surg Oncol. 2014;110: 960-966.
    • (2014) J Surg Oncol. , vol.110 , pp. 960-966
    • Sugawara, A.1    Kunieda, E.2
  • 21
    • 84883796070 scopus 로고    scopus 로고
    • Impact of adjuvant radiotherapy on survival after pancreatic cancer resection: An appraisal of data from the National Cancer Data Base
    • Kooby D, Gillespie T, Liu Y, et al. Impact of adjuvant radiotherapy on survival after pancreatic cancer resection: an appraisal of data from the National Cancer Data Base. Ann Surg Oncol. 2013;20: 3634-3642.
    • (2013) Ann Surg Oncol. , vol.20 , pp. 3634-3642
    • Kooby, D.1    Gillespie, T.2    Liu, Y.3
  • 22
    • 0027511678 scopus 로고
    • Resection margins in carcinoma of the head of the pancreas Implications for radiation therapy
    • Willett CG, Lewandrowski K, Warshaw AL, Efird J, Compton CC. Resection margins in carcinoma of the head of the pancreas. Implications for radiation therapy. Ann Surg. 1993;217:144-148.
    • (1993) Ann Surg. , vol.217 , pp. 144-148
    • Willett, C.G.1    Lewandrowski, K.2    Warshaw, A.L.3    Efird, J.4    Compton, C.C.5
  • 23
    • 84865586712 scopus 로고    scopus 로고
    • Microscopic margins and patterns of treatment failure in resected pancreatic adenocarcinoma
    • Gnerlich JL, Luka SR, Deshpande AD, et al. Microscopic margins and patterns of treatment failure in resected pancreatic adenocarcinoma. Arch Surg. 2012;147:753-760.
    • (2012) Arch Surg. , vol.147 , pp. 753-760
    • Gnerlich, J.L.1    Luka, S.R.2    Deshpande, A.D.3
  • 24
    • 21044451123 scopus 로고    scopus 로고
    • Meta-Analysis of randomised adjuvant therapy trials for pancreatic cancer
    • Stocken DD, Buchler MW, Dervenis C, et al. Meta-Analysis of randomised adjuvant therapy trials for pancreatic cancer. Br J Cancer. 2005;92:1372-1381.
    • (2005) Br J Cancer. , vol.92 , pp. 1372-1381
    • Stocken, D.D.1    Buchler, M.W.2    Dervenis, C.3
  • 25
    • 84155164281 scopus 로고    scopus 로고
    • Perineural invasion and lymph node involvement as indicators of surgical outcome and pattern of recurrence in the setting of preoperative gemcitabinebased chemoradiation therapy for resectable pancreatic cancer
    • Takahashi H, Ohigashi H, Ishikawa O, et al. Perineural invasion and lymph node involvement as indicators of surgical outcome and pattern of recurrence in the setting of preoperative gemcitabinebased chemoradiation therapy for resectable pancreatic cancer. Ann Surg. 2012;255:95-102.
    • (2012) Ann Surg. , vol.255 , pp. 95-102
    • Takahashi, H.1    Ohigashi, H.2    Ishikawa, O.3
  • 27
    • 34250829023 scopus 로고    scopus 로고
    • Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy
    • Krishnan S, Rana V, Janjan NA, et al. Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy. Cancer. 2007;110:47-55.
    • (2007) Cancer. , vol.110 , pp. 47-55
    • Krishnan, S.1    Rana, V.2    Janjan, N.A.3
  • 28
    • 33846908072 scopus 로고    scopus 로고
    • Impact of chemoradiotherapy after disease control with chemotherapy in locally advanced pancreatic adenocarcinoma in GERCOR phase II and III studies
    • Huguet F, Andre T, Hammel P, et al. Impact of chemoradiotherapy after disease control with chemotherapy in locally advanced pancreatic adenocarcinoma in GERCOR phase II and III studies. J Clin Oncol. 2007;25:326-331.
    • (2007) J Clin Oncol. , vol.25 , pp. 326-331
    • Huguet, F.1    Andre, T.2    Hammel, P.3
  • 29
    • 3042697976 scopus 로고    scopus 로고
    • Chemotherapy for pancreatic cancer
    • Crane CH, Ben-Josef E, Small Jr. W. Chemotherapy for pancreatic cancer. N Engl J Med. 2004;350:2713-2715.
    • (2004) N Engl J Med. , vol.350 , pp. 2713-2715
    • Crane, C.H.1    Ben-Josef, E.2    Small, W.3
  • 30
    • 3042697976 scopus 로고    scopus 로고
    • Chemotherapy for pancreatic cancer
    • Bydder S, Spry N. Chemotherapy for pancreatic cancer. N Engl J Med. 2004;350:2713-2715.
    • (2004) N Engl J Med. , vol.350 , pp. 2713-2715
    • Bydder, S.1    Spry, N.2
  • 32
    • 1542720458 scopus 로고    scopus 로고
    • Adjuvant therapy for pancreatic cancer-Dhe debate continues
    • Choti MA. Adjuvant therapy for pancreatic cancer-Dhe debate continues. N Engl J Med. 2004;350:1249-1251.
    • (2004) N Engl J Med. , vol.350 , pp. 1249-1251
    • Choti, M.A.1
  • 33
    • 84995744010 scopus 로고    scopus 로고
    • Adjuvant chemoradiation for pancreatic cancer: What does the evidence tell us?
    • Chuong MD, Boggs DH, Patel KN, Regine WF. Adjuvant chemoradiation for pancreatic cancer: what does the evidence tell us? J Gastrointest Oncol. 2014;5:166-177.
    • (2014) J Gastrointest Oncol. , vol.5 , pp. 166-177
    • Chuong, M.D.1    Boggs, D.H.2    Patel, K.N.3    Regine, W.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.