TRPC6 channel translocation into phagosomal membrane augments phagosomal function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 47, 2015, Pages E6486-E6495

  Riazanski, Vladimir ^a   Gabdoulkhakova, Aida G ^a   Boynton, Lin S ^a   Eguchi, Raphael R ^a   Deriy, Ludmila V ^a   Hogarth, D Kyle ^a   Loaëc, Nadège ^b   Oumata, Nassima ^b   Galons, Hervé ^c   Brown, Mary E ^a   Shevchenko, Pavel ^a   Gallan, Alexander J ^a   Yoo, Sang Gune ^a   Naren, Anjaparavanda P ^d   Villereal, Mitchel L ^a   Beacham, Daniel W ^e   Bindokas, Vytautas P ^a   Birnbaumer, Lutz ^f   Meijer, Laurent ^b   Nelson, Deborah J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Centre de Perharidy   (France)

^c Centre National de la Recherche Scientifique   (France)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e MOLECULAR PROBES INC   (United States)

^f NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alveolar macrophage; Cystic fibrosis; Phagosome; Roscovitine; TRPC6

Indexed keywords

PROTON PUMP; ROSCOVITINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; ACID; CALCIUM; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIACYLGLYCEROL; G PROTEIN COUPLED RECEPTOR; MOLECULAR LIBRARY; PERTUSSIS TOXIN; PURINE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC6 PROTEIN, HUMAN; TRPC6 PROTEIN, MOUSE;

ACIDIFICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERICIDAL ACTIVITY; CALCIUM SIGNALING; CELL MEMBRANE; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; LUNG INFECTION; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOSOME; PRIORITY JOURNAL; PROTON TRANSPORT; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CHANNEL GATING; CHEMISTRY; DRUG EFFECTS; EXOCYTOSIS; FLUORESCENT ANTIBODY TECHNIQUE; INTRACELLULAR MEMBRANE; METABOLISM; MICROBIAL VIABILITY; MOLECULAR LIBRARY; PATCH CLAMP TECHNIQUE; PHARMACOLOGY; PROTEIN TRANSPORT;

ACIDS; ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; CELL MEMBRANE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIGLYCERIDES; EXOCYTOSIS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTRACELLULAR MEMBRANES; ION CHANNEL GATING; MACROPHAGES, ALVEOLAR; MICE; MICROBIAL VIABILITY; MODELS, BIOLOGICAL; PATCH-CLAMP TECHNIQUES; PERTUSSIS TOXIN; PHAGOSOMES; PROTEIN TRANSPORT; PURINES; RECEPTORS, G-PROTEIN-COUPLED; SMALL MOLECULE LIBRARIES; TRPC CATION CHANNELS;

EID: 84948398452     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1518966112     Document Type: Article

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