SELEX: How It Happened and Where It will Go

Journal of Molecular Evolution

Volumn 81, Issue 5-6, 2015, Pages 140-143

  Gold, Larry ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER;

HISTORY; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; UNITED STATES;

APTAMERS, NUCLEOTIDE; HISTORY, 20TH CENTURY; SELEX APTAMER TECHNIQUE; UNITED STATES;

EID: 84948380581     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-015-9705-9     Document Type: Review

References (4)

1. Ellington AD, Szostak JW (1990) In vitro selection of RNA molecules that bind specific ligands. Nature 346(6287):818–822
2. Hathout Y, Brody E, Clemens PR, Cripe L, DeLisle RK, Furlong P, Gordish-Dressman H, Hache L, Henricson E, Hoffman EP, Kobayashi YM, Lorts A, Mah JK, McDonald C, Mehler B, Nelson S, Nikrad M, Singer B, Steele F, Sterling D, Sweeney HL, Williams S, Gold L (2015) Large-scale serum protein biomarker discovery in Duchenne muscular dystrophy. Proc Natl Acad Sci USA 112(23):7153–7158
3. Oliphant AR, Struhl K (1989) An efficient method for generating proteins with altered enzymatic properties: application to beta-lactamase. Proc Natl Acad Sci USA 86(23):9094–9098
4. Tuerk C, Gold L (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249(4968):505–510