Is asthma prevalence still increasing?

Expert Review of Respiratory Medicine

Volumn 10, Issue 1, 2016, Pages 39-51

  Lundbäck, Bo ^a,b   Backman, Helena ^b   Lötvall, Jan ^a   Rönmark, Eva ^b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

Asthma; Epidemiology; Population studies; Prevalence

Indexed keywords

ASTHMA; AUSTRALIA; EUROPE; HUMAN; MULTICENTER STUDY (TOPIC); NORTH AMERICA; POPULATION RESEARCH; PREVALENCE; REVIEW; TREND STUDY; URBANIZATION; URBAN POPULATION;

ASTHMA; AUSTRALIA; EUROPE; HUMANS; PREVALENCE; URBAN POPULATION;

EID: 84948172646     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/17476348.2016.1114417     Document Type: Review

References (117)

1. Woolcock AJ. The problem of asthma worldwide. Eur Respir Rev. 1991;1:361-368.
2. Sears MR. Epidemiological trends in bronchial asthma. In: Kalliner M, Barnes P, Persson C, editors. Asthma: its pathology and treatment. Lung biology in health & disease Vol. 49. New York (NY): Marcel Dekker Inc.; 1991. p. 1-49.
3. Lundbäck B. Epidemiology of rhinitis and asthma. Clin Exp Allergy. 1998;28(S2):3-10.
4. Anderson HR, Gupta R, Strachan DP, et al. 50 years of asthma: UK trends from 1955 to 2004. Thorax. 2007;62:85-90.
5. Ma Y, Zhao J, Ha ZR, et al. Very low prevalence of asthma and allergies in schoolchildren from rural Beijing, China. Pediatr Pulmonol. 2009;44(8):793-799. Exemplifies urban-rural difference in asthma prevalence in developing countries.
6. Devenny A, Wassall H, Ninan T, et al. Respiratory symptoms and atopy in children in Aberdeen: questionnaire studies of a defined school population repeated over 35 years. BMJ. 2004;329:489-490. Exemplify that increase in asthma prevalence may be leveling off in the UK.
7. Ng Man Kwong G, Proctor A, Billings C, et al. Increasing prevalence of asthma diagnosis and symptoms in children is confined to mild symptoms. Thorax. 2001;56(4):312-314. Exemplify that increase in asthma prevalence may be leveling off in the UK.
8. Anderson HR, Ruggles R, Dp S, et al. Trends in prevalence of symptoms of asthma, hay fever, and eczema in 12-14 year olds in the British Isles, 1995-2002: questionnaire survey. BMJ. 2004;328:1052-1053. Exemplify that increase in asthma prevalence may be leveling off in the UK.
9. Braun-Fahrlander C, Gassner M, Grize L, et al. No further increase in asthma, hay fever and atopic sensitisation in adolescents living in Switzerland. Eur Respir J. 2004;23(3):407-413. Exemplify that increase in asthma prevalence may be leveling off in Switzerland.
10. Zöllner IK, Weiland SK, Piechotowski I, et al. No increase in the prevalence of asthma, allergies and atopic sensitization among children in Germany: 1992-2001. Thorax. 2005;60:545-548. Exemplify that increase in asthma prevalence may be leveling off in Germany.
11. Robertson CF, Roberts MF, Kappers JH. Asthma prevalence in Melbourne schoolchildren: have we reached the peak? Med J Aust. 2004;180(6):273-276. No further increase in asthma prevalence in Australian children.
12. Toelle BG, Ng K, Belousova E, et al. Prevalence of asthma and allergy in schoolchildren in Belmont, Australia: three cross sectional surveys over 20 years. BMJ. 2004;328:386. No further increase in asthma prevalence in Australian children.
13. Wennergren G. The prevalence of asthma has reached a plateau. Acta Paediatr. 2011;100:938-939.
14. Anandan C, Nurmatov U, Ocp VS, et al. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy. 2010;65:152-167. Detailed review on changes in asthma prevalence worldwide. Focus mainly on children and teenagers. Net effect worldwide: still an increase.
15. Asher MI, Keil U, Anderson HR, et al. International study of asthma and allergy in childhood (ISAAC): Rationale and methods. Eur Respir J. 1995;8:483-491.
16. Sears MR. Trends in the prevalence of asthma. Chest. 2014;145(2):219-225. Excellent review of asthma prevalence trends and risk factors for asthma.
17. Von Hertzen L, Haahtela T. Signs of reversing trends in prevalence of asthma. Allergy. 2005;60:283-292.
18. European Respiratory Society. The European Lung White Book. Respiratory health and disease in Europe. Gibson GJ, Loddenkemper R, Sibille Y, et al., editors. Sheffield (UK): European Respiratory Society Publications; 2013. Summary of respiratory diseases including asthma in Europe including prevalence and burden of disease.
19. Gibson GJ, Loddenkemper R, Lundbäck B, et al. Respiratory health and disease in Europe: the new European Lung White Book. Eur Respir J. 2013;42(3):559-563.
20. Asher MI, Montefort S, Björkstén B, et al. the ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet. 2006;368:733-743. Key-paper describing changes in prevalence of asthma and allergic diseases among children and teenagers worldwide
21. Eder W, Mj E, Von Mutius E. The Asthma Epidemic. N Engl J Med. 2006;355:2226-2235. Excellent review of asthma prevalence and risk factors
22. Pride NB. Revision of the European Community for Coal and Steel Questionnaire on respiratory symptoms. Eur Respir J. 1989;2:697-699.
23. Samet JM. Epidemiologic approaches for the identification of asthma. Chest. 1987;91(S):74-78.
24. Toren K, Brisman J, Jarvholm B. Asthma and asthma-like symptoms in adults assessed by questionnaires. A literature review. Chest. 1993;104:600-608.
25. Lundbäck B, Rönmark E, Jönsson E, et al. Incidence of physician-diagnosed asthma in adults -A real incidence or a result of increased awareness? Report from the obstructive lung disease in Northern Sweden studies. Respir Med. 2001;95:685-692.
26. Fletcher CM, Elmes PC, Fairbairn AS, et al. The significance of respiratory symptoms and the diagnosis of chronic bronchitis in a working population. Br Med J. 1959;2:257-266.
27. Fairbairn AS, Wood CH, Fletcher CM. Variability in answers to a questionnaire on respiratory symptoms. Br J Prev Soc Med. 1959;13:175-193.
28. Lebowitz MD, Burrows B. Comparison of questionnaires: the BMRC and NHLI respiratory questionnaires and a new self-completion questionnaire. Am Rev Respir Dis. 1976;113:627-635.
29. Bergmann MM, Jacobs EJ, Hoffmann K, et al. Agreement of self-reported medical history: comparison of an in-person interview with a self-administered questionnaire. Eur J Epidemiol. 2004;19:411-416.
30. Cerveri I, Bruschi C, Ricciardi M, et al. Epidemiological diagnosis of asthma: methodological considerations of prevalence evaluation. Eur J Epidemiol. 1987;3:202-205.
31. Lundbäck B, Stjernberg N, Rosenhall L, et al. Methacholine reactivity and asthma. Report from the Northern Sweden Obstructive Lung Disease Project. Allergy. 1993;48:117-124.
32. Crane J, Mallol J, Beasley R, et al. International Study of Asthma and Allergies in Childhood Phase I study group. Agreement between written and video questions for comparing asthma symptoms in ISAAC. Eur Respir J. 2003;21(3):455-461.
33. Aaron SD, Vandenhem KL, Boulet LP, et al. Overdiagnosis of asthma in obese and non-obese adults. CMAJ. 2008;179(11):1121-1131.
34. Heffler E, Pizzimenti S, Guida G, et al.. Prevalence of over-/misdiagnosis of asthma in patients referred to an allergy clinic. J Asthma. 2015;1-4. Epub ahead of print Aug. 19.
35. Burney PG, Luczynska C, Chinn S, et al. The European Community Respiratory Health Survey. Eur Respir J. 1994;7:954-960.
36. Chinn S, Jarvis D, Burney P, et al. Increase in diagnosed asthma but not in symptoms in the European Community Respiratory Health Survey. Thorax. 2004;59:646-651. The ECRHS' cohort follow-up survey. Increase in diagnosed asthma but not in symptoms.
37. Frankel LH, Dublin LI. Sickness survey of principal cities in Pennsylvania and West Virginia. New York (NY): Metropolitan Life Insurance Co.; 1917.
38. Rackemann FM. Clinical allergy-asthma and hay fever. New York (NY): The MacMillan Co.; 1931.
39. Stocks P. Sickness in the population of England and Wales in 1944-1947. Studies on Medical and Population Subjects. London, UK. HMSO. 1949;2:1-51.
40. Claussen J. Asthma in Norway. Nord Med. 1948;37:525-530.
41. Kraepelin S. The frequency of bronchial asthma in Swedish school children. Acta Paediatr Scand. 1954;43(100S):149-153.
42. Grant G. Asthma among undergraduates at the University of Wales. Acta Allergol. 1957;11:37-44.
43. Broder I, Barlow P, Horton R. The epidemiology of asthma and hay fever in a total community, Tecumseh, Michigan. J Allergy. 1962;33:513-523.
44. Mannino DM, Homa DM, Akinbami LJ, et al. Surveillance for asthma-United States, 1980-1999. MMVR Surveil Summ. 2002;51:1-13.
45. Upton MN, McConnachie A, McSharry C, et al. Intergenerational 20 year trends in the prevalence of asthma and hay fever in adults: the Midspan family study surveys of parents and offspring. BMJ. 2000;321:88-92.
46. Latvala J, Von Hertzen L, Lindholm H, et al. Trends in prevalence of asthma and allergy in Finnish young men: nationwide study, 1966-2003. BMJ. 2005;330:1186-1187.
47. Áberg N. Asthma and allergic rhinitis in Swedish conscripts. Clin Exp Allergy. 1989;19(1):59-63.
48. Bråbäck L, Hjern A, Rasmussen F. Trends in asthma, allergic rhinitis and eczema among Swedish conscripts from farming and non-farming environments. A nationwide study over three decades. Clin Exp Allergy. 2004;34(1):38-43.
49. Alanko K. Prevalence of asthma in a Finnish rural population -A study of symptomatic subjects tested for bronchial hyperreactivity. Scand J Respir Dis. 1970;76S:1-64.
50. Julin A, Wilhelmsen L. Bronchial asthma and chronic bronchitis in a random population sample. Prevalence, clinical findings and socio-economic factors. Scand J Respir Dis. 1967;48:330-342.
51. Gulsvik A. Prevalence and manifestations of obstructive lung disease in the city of Oslo. Scand J Respir Dis. 1979;60:286-296.
52. Pedersen PA, Weeke ER Epidemiology of asthma in Denmark. Chest. 1987;91S:107-113.
53. Kiviloog J, Irnell L, Eklund G. The prevalence of bronchial asthma and chronic bronchitis in smokers and non-smokers in a representative Swedish population. Scand J Respir Dis. 1974;55:262-276.
54. Stjernberg N, Eklund A, Nyström L, et al. Prevalence of bronchial asthma and chronic bronchitis in a community in northern Sweden. Eur J Respir Dis. 1985;67:41-49.
55. Broder I, Higgins MW, Mathew KP. Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan 3. J All Clin Immunol. 1974;53:127-132.
56. Lebowitz MD, Knudson RJ, Burrows B. Tucson Epidemiologic study of obstructive lung diseases. I. Methodology and prevalence of disease. Am J Epidemiol. 1975;102:137-152.
57. Lundbäck B, Nyström L, Rosenhall L, et al. Obstructive lung disease in northern Sweden: respiratory symptoms assessed in a postal survey. Eur Respir J. 1991;4(3):257-266.
58. Larsson L, Boetius G, Uddenfelt M. Differences in utilization of asthma drugs between two Swedish provinces-relation to symptoms reporting. Eur Respir J. 1993;6:198-203.
59. Larsson L, Boëthius G, Uddenfeldt M. Differences in utilisation of asthma drugs between two neighbouring Swedish provinces: relation to prevalence of obstructive airway disease. Thorax. 1994;49(1):41-49.
60. Charpin D, Vervloet D, Charpin J. Epidemiology of asthma in Western Europe. Allergy. 1988;43:481-492.
61. Paoletti P, Carmignani G, Viegi G. Prevalence of asthma and asthmatic symptoms in a general population sample of north Italy. Eur Respir J. 1989;2(6S):527-531.
62. Miller A, Thornton JA, Anderson HA, et al. Clinical respiratory abnormalities in Michigan-prevalence by sex and smoking history in representative samples of the adult population. Chest. 1988;94:1187-1194.
63. Manfreda J, Becker AB, Wang PZ, et al. Transient physician-diagnosed asthma. Prevalence in Manitoba between 1980 and 1990. Chest.; 103:158-167.
64. Haahtela T, Lindholm H, Bjorksten F, et al. Prevalence of asthma in Finnish young men. BMJ. 1990;301:266-268.
65. Vesterinen E, Kaprio J, Koskenvou M. Prospective study of asthma in relation to smoking habits among 14 729 adults. Thorax. 1988;43:534-539.
66. Vondra V, Baly J, Mazakova H. Epidemiology of bronchial asthma and bronchial hyperreactivity in adults. Eur Respir J. 1989;2(8S):868.
67. Woolcock AJ, Peat JK, Salome CM, et al., et al Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population. Thorax. 1987;42:361-368.
68. Abramson MJ, Hensley MJ, Saunders NA, et al. Evaluation of a new asthma questionnaire. J Asthma. 1991;28:129-139.
69. Toelle BG, Peat JK, Salome CM, et al. Towards a definition of asthma for epidemiology. Am Rev Respir Dis. 1992;146:633-637.
70. Sears MR. Epidemiology of asthma. In: Flenley DC, Petty DL, editors. Recent advances in respiratory medicine. Vol. 4. Edinburgh (Scotland): Churchill; 1986. p. 1-11.
71. Janson C, Chinn S, Jarvis D, et al. Physician-diagnosed asthma and drug utilization in the European Community Respiratory Health Survey. Eur Respir J. 1997;10(8):1795-1802.
72. Pallasaho P, Lundbäck B, Läspä S-L, et al. Increasing prevalence of asthma but not of chronic bronchitis in Finland? Report from the FinEsS-Helsinki study. Respir Med. 1999;93:798-809.
73. Kotaniemi J, Lundbäck B, Nieminen M, et al. Increase of asthma in adults in Northern Finland - a report from The FinEsS study. Allergy. 2001;56:169-174.
74. Meren M, Jannus-Pruljan L, Loit H-M, et al. Asthma, chronic bronchitis and respiratory symptoms among adults in Estonia. Respir Med. 2001;95:954-964.
75. Pallasaho P, Lundback B, Meren M, et al. Prevalence and risk factors for asthma and chronic bronchitis in the capitals Helsinki, Stockholm, and Tallinn. Respir Med. 2002;96(10):759-769. Exemplifies difference in prevalence of diagnosed asthma between Eastern and Western Europe although similar prevalence of symptoms common in asthma.
76. Kainu A, Pallasaho P, Piirila P, et al. Increase in prevalence of physician-diagnosed asthma in Helsinki during the Finnish asthma programme: improved recognition of asthma in primary care? A cross-sectional cohort study. Prim Care Respir J. 2013;22(1):64-71. Increase in prevalence of diagnosed asthma but not in symptoms common in asthma among adults in Helsinki, Finland.
77. Ekerljung L, Andersson A, Sundblad BM, et al. Has the increase in the prevalence of asthma and respiratory symptoms reached a plateau in Stockholm, Sweden? Int J Tuberc Lung Dis. 2010;14(6):764-771.
78. Backman H, Hedman L, Jansson SA, et al. Prevalence trends in respiratory symptoms and asthma in relation to smoking-two cross-sectional studies ten years apart among adults in northern Sweden. World Allergy Organ J. 2014;7(1):1. Increase in prevalence of diagnosed asthma but not in symptoms common in asthma among adults in northern Sweden.
79. Björnsson E, Plaschke P, Norrman E, et al. Symptoms related to asthma and chronic bronchitis in three areas of Sweden. Eur Respir J. 1994;7(12):2146-2153.
80. Lötvall J, Ekerljung L, Ronmark ep, et al. West Sweden Asthma Study: prevalence trends over the last 18 years argues no recent increase in asthma. Respir Res. 2009;10:e94. Increase in prevalence of diagnosed asthma but not in symptoms common in asthma among adults in south-west of Sweden.
81. Bjerg A, Ekerljung L, Middelveld R, et al. Increased prevalence of symptoms of rhinitis but not of asthma between 1990 and 2008 in Swedish adults: comparisons of the ECRHS and GA (2) LEN surveys. PLoS One. 2011;6(2):e16082.
82. Wilson DH, Adams RJ, Tucker D, et al. Trends in asthma prevalence and population changes in South Australia, 1990-2003. Med J Aust. 2006;184:226-229. Since late 1990s, no further increase in prevalence of asthma in asthma among South Australian adults.
83. Browatzki A, Ulrik CS, Lange P. Prevalence and severity of self-reported asthma in young adults, 1976-2004. Eur Respir J. 2009;34(5):1046-1051.
84. de Marco R, Cappa V, Accordini S, et al. Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010. Eur Respir J. 2012;39:883-892. Increase in prevalence of asthma and some increase in symptoms common in asthma according to three nationwide Italian studies.
85. de Marco R, Verlato G, Zanolin ME, et al. Nonresponse bias in EC Respiratory Health Survey in Italy. Eur Respir J. 1994;7:2139-2245.
86. de Marco R, Poli A, Ferrari M, et al. The impact of climate and traffic-related NO2 on the prevalence of asthma and allergic rhinitis in Italy. Clin Exp Allergy. 2002;32:1405-1412.
87. de Marco R, Accordini S, Antonicelli L, et al. The gene environmental interactions in respiratory diseases (GEIRD) project. Int Arch Allergy Immunol. 2010;152:255-263.
88. James AL, Knuiman MW, Divitini ML, et al. Changes in the prevalence of asthma in adults since 1966: the Busselton health study. Eur Respir J. 2010;35(2):273-278. Major increase in prevalence of asthma over four decades but less so regarding symptoms. However, no data about changes after the millennium shift
89. QRESEARCH and the Information Centre for health and social care. Primary care epidemiology of allergic disorders: analysis using QRESEARCH database 2001-2006 [Internet]. Final Report to the Information Centre and Department of Health. 2007 [cited 2015 Nov. 16]. Available from: http://www.qre search.org/Public-Documents/HSCIC% 20allergies%20report%20from% 20QRESEARCH%20.pdf
90. Arif AA, Delclos GL, Lee ES, et al. Prevalence and risk factors of asthma and wheezing among US adults: an analysis of the NHANES III data. Eur Respir J. 2003;21(5):827-833.
91. Gershon AS, Guan J, Wang C, et al. Trends in asthma prevalence and incidence in Ontario, Canada, 1966-2005: A population study. Am J Epidemiol. 2010;172:728-736.
92. Burr ML, Wat D, Evans C, et al. Asthma prevalence in 1973, 1998 and 2003. Thorax. 2006;61:296-299.
93. Meren M, Raukas-Kivioja A, Jannus-Pruljan L, et al. Low prevalence of asthma in westernizing countries-myth or reality? Prevalence of asthma in Estonia-report from the "FinEsS" study. J Asthma. 2005;42:359-365. Exemplifies under-diagnosis of adult asthma in Eastern Europe.
94. Laatikainen T, Von Hertzen L, Koskinen JP, et al. Allergy gap between Finnish and Russian Karelia on increase. Allergy. 2011;66(7):886-892.
95. Nowak D, Heinrich J, Jörres R, et al. Prevalence of respiratory symptoms, bronchial hyperresponsiveness and atopy among adults: west and east Germany. Eur Respir J. 1996;9(12):2541-2552.
96. Meren M, Loit HM, Raukas-Kivioja A, et al. Decrease in respiratory symptoms parallels to a decrease in smoking in Estonia. Eur Respir J. 2009;34(S53):A3333.
97. Montnemery P, Ädelroth E, Heuman K, et al. Prevalence of obstructive lung diseases and respiratory symptoms in southern Sweden. Respir Med. 1998;92(12):1337-1345.
98. Larsson M, Hallström J, Frisk M, et al. Environmental tobacco smoke exposure during childhood is associated with increased prevalence of asthma in adults. Chest. 2001;120:711-717.
99. Bjerg A, Sandström T, Lundbäck B, et al. Time trends in asthma and wheeze in Swedish children 1996-2006: prevalence and risk factors by sex. Allergy. 2010;65(1):48-55.
100. Andersson M, Bjerg A, Forsberg B, et al. The clinical expression of asthma in schoolchildren has changed between 1996 and 2006. Pediatr All Immunol. 2010;21(5):859-866.
101. Rönmark E, Bjerg A, Perzanowski M, et al. Major increase in allergic sensitization in school children from 1996 to 2006 in Northern Sweden. J Allergy Clin Immunol. 2009;124(2):357-363. Major increase in asthma prevalence of allergic sensitization may precede increase in asthma prevalence.
102. Akasawa A, Akashi M, Aota A, et al. The first nationwide survey of asthma prevalence in Japan using ISAAC and ECRHS questionnaire. J All Clin Immunol. 2007;119(S):e170.
103. Lam HT, Rönmark E, Tuong NV, et al. Increase in asthma and a high prevalence of bronchitis: results from a population study among adults in urban and rural Vietnam. Respir Med. 2011;105:177-185.
104. Sy DQ, Than Binh MH, Quoc NT, et al., Prevalence of asthma and asthma-like symptoms in Dalat Highlands, Vietnam. Singapore Med J. 2007;48:294-303.
105. Chan-Yeung M, Zhang LX, Tu DH, et al. The prevalence of asthma and asthma-like symptoms among adults in rural Beijing, China. Eur Respir J. 2002;19:853-858.
106. Jindal SK, Aggarwal AN, Gupta D, et al. Indian study on epidemiology of asthma, respiratory symptoms and chronic bronchitis in adults (INSEARCH). Int J Tuberc Lung Dis. 2012;16(9):1270-1277.
107. Aggarwal AN, Chaudhry K, Chabra SK, et al. Prevalence and risk factors for bronchial asthma in Indian adults: a multicentre study. Indian j Chest Dis Allied Soc. 2006;48(1):13-22.
108. Adeloye D, Chan KY, Rudan I, et al. An estimate of asthma in Africa: a systematic review. Croat Med J. 2013;54:519-531.
109. Wjst M, Boakye D. Asthma in Africa. PLoS Med. 2007;4:e72.
110. van Gemert F, van der Molen D, Jones R, et al. The impact of asthma and COPD in sub-Saharan Africa. Prim Care Respir J. 2011;20:240-248.
111. Ait-Khaled N, Odhiambo J, Pearce N, et al. Prevalence of symptoms of asthma, rhinitis and eczema in 13- to 14-year-old children in Africa: the International Study of Asthma and Allergies in Childhood Phase III. Allergy. 2007;62(3):247-258.
112. Ehrlich RI, White N, Norman R, et al. Wheeze, asthma diagnosis and medication use: a national adult survey in a developing country. Thorax. 2005;60:895-901.
113. Nafti S, Taright S, El Ftouh M, et al. Prevalence of asthma in North Africa: the Asthma Insights and Reality in the Maghreb (AIRMAG) study. Respir Med. 2009;103(S2):2-11.
114. Erhabor GE, Agbroko SO, Bamigboye P, et al. Prevalence of asthma symptoms among university students 15 to 35 years of age in Obafemi Awolowo University, Ile-Ife, Osun State. J Asthma. 2006;43:161-164.
115. Desalu OO, Oluboyo PO, Salami AK. The prevalence of bronchial asthma among adults in Ilorin, Nigeria. Afr J Med Med Sci. 2009;38:149-154.
116. To T, Stanojevic S, Moores G, et al. Global asthma prevalence in adults: findings from the cross-sectional world health survey. BMC Publ Health. 2012;12:e204.
117. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet. 1998;351:1225-1232.