Current Estimate of Costs of Lung Cancer Screening in the United States

Thoracic Surgery Clinics

Volumn 25, Issue 2, 2015, Pages 205-215

  Mauchley, David C ^a   Mitchell, John D ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Budget impact model; Cost effectiveness; Early lung cancer action project (ELCAP); Low dose computed tomography (LDCT); Lung cancer screening; National lung screening trial (NLST)

Indexed keywords

BRONCHOSCOPY; CANCER MORTALITY; CANCER SCREENING; COMPUTER ASSISTED TOMOGRAPHY; COST BENEFIT ANALYSIS; COST CONTROL; COST EFFECTIVENESS ANALYSIS; ECONOMIC EVALUATION; FALSE POSITIVE RESULT; HEALTH CARE COST; HEALTH CARE UTILIZATION; HIGH RISK POPULATION; HUMAN; LUNG BIOPSY; LUNG CANCER; MEDIASTINOSCOPY; PRIORITY JOURNAL; QUALITY ADJUSTED LIFE YEAR; REVIEW; SMOKING CESSATION; SPIRAL COMPUTER ASSISTED TOMOGRAPHY; THORACOSCOPY; THORACOTOMY; THORAX RADIOGRAPHY; UNITED STATES; EARLY DIAGNOSIS; ECONOMICS; LUNG TUMOR; MASS SCREENING; PROCEDURES; RADIATION DOSE; RADIOGRAPHY; RISK;

COST-BENEFIT ANALYSIS; EARLY DETECTION OF CANCER; HEALTH EXPENDITURES; HUMANS; LUNG NEOPLASMS; MASS SCREENING; RADIOTHERAPY DOSAGE; RISK; TOMOGRAPHY, X-RAY COMPUTED; UNITED STATES;

EID: 84948086372     PISSN: None     EISSN: 15585069     Source Type: Journal    
DOI: 10.1016/j.thorsurg.2014.12.005     Document Type: Review

References (24)

1. National Lung Screening Trial Research Team, Aberle D.R., Adams A.M., et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N England J Med 2011, 365:395-409.
2. Moyer V.A., US Preventive Services Task Force Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2014, 160:330-338.
3. Henschke C.I., McCauley D.I., Yankelevitz D.F., et al. Early lung cancer action project: overall design and findings from baseline screening. Lancet 1999, 354:99-105.
4. Marshall D., Simpson K.N., Earle C.C., et al. Potential cost-effectiveness of one-time screening for lung cancer (LC) in a high risk cohort. Lung Cancer 2001, 32:227-236.
5. Marshall D., Simpson K.N., Earle C.C., et al. Economic decision analysis model of screening for lung cancer. Eur J Cancer 2001, 37:1759-1767.
6. Wisnivesky J.P., Mushlin A.I., Sicherman N., et al. The cost-effectiveness of low-dose CT screening for lung cancer: preliminary results of baseline screening. Chest 2003, 124:614-621.
7. Mahadevia P.J., Fleisher L.A., Frick K.D., et al. Lung cancer screening with helical computed tomography in older adult smokers: a decision and cost-effectiveness analysis. JAMA 2003, 289:313-322.
8. Manser R., Dalton A., Carter R., et al. Cost-effectiveness analysis of screening for lung cancer with low dose spiral CT (computed tomography) in the Australian setting. Lung Cancer 2005, 48:171-185.
9. McMahon P.M., Kong C.Y., Bouzan C., et al. Cost-effectiveness of computed tomography screening for lung cancer in the United States. J Thorac Oncol 2011, 6:1841-1848.
10. Villanti A.C., Jiang Y., Abrams D.B., et al. A cost-utility analysis of lung cancer screening and the additional benefits of incorporating smoking cessation interventions. PLoS One 2013, 8:e71379.
11. Goulart B.H., Bensink M.E., Mummy D.G., et al. Lung cancer screening with low-dose computed tomography: costs, national expenditures, and cost-effectiveness. J Natl Compr Canc Netw 2012, 10:267-275.
12. Pierce J.P., Messer K., White M.M., et al. Prevalence of heavy smoking in California and the United States, 1965-2007. JAMA 2011, 305:1106-1112.
13. Breen N., Gentleman J.F., Schiller J.S. Update on mammography trends: comparisons of rates in 2000, 2005, and 2008. Cancer 2011, 117:2209-2218.
14. Patz E.F., Pinsky P., Gatsonis C., et al. Overdiagnosis in low-dose computed tomography screening for lung cancer. JAMA Intern Med 2014, 174:269-274.
15. Mariotto A.B., Yabroff K.R., Shao Y., et al. Projections of the cost of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011, 103:117-128.
16. National Cancer Institute Surveillance epidemiology and end results 2013, National Institute of Health, Bethesda (MD), Available at:, Accessed August 14, 2014. http://seer.cancer.gov/.
17. Hanmer J., Lawrence W.F., Anderson J.P., et al. Report of nationally representative values for the noninstitutionalized US adult population for 7 health-related quality-of-life scores. Med Decis Making 2006, 26:391-400.
18. Pyenson B.S., Sander M.S., Jiang Y., et al. An actuarial analysis shows that offering lung cancer screening as an insurance benefit would save lives at relatively low cost. Health Aff 2012, 31:770-779.
19. Braithwaite R.S., Meltzer D.O., King J.T., et al. What does the value of modern medicine say about the $50,000 per quality-adjusted life-year decision rule?. Med Care 2008, 46:349-356.
20. Mulshine J.L., Jablons D.M. Volume CT for diagnosis of nodules found in lung-cancer screening. N Engl J Med 2009, 361:2281-2282.
21. van Klaveren R.J., Oudkerk M., Prokop M., et al. Management of lung nodules detected by volume CT scanning. N Engl J Med 2009, 361:2221-2229.
22. Ostroff J.S., Buckshee N., Mancuso C.A., et al. Smoking cessation following CT screening for early detection of lung cancer. Prev Med 2001, 33:613-621.
23. Pinsky P.F., Gierada D.S., Hocking W., et al. National lung screening trial findings by age: Medicare-eligible versus under-65 population. Ann Intern Med 2014, 161(9):627-633.
24. Roth J.A., Sullivan S.D., Ravelo A., et al. Low-dose computed tomography lung cancer screening in the Medicare program: projected clinical, resource, and budget impact. J Clin Oncol 2014, 32(15 suppl):6501.