Effects of artificial light at night on human health: A literature review of observational and experimental studies applied to exposure assessment

Chronobiology International

Volumn 32, Issue 9, 2015, Pages 1294-1310

  Cho, YongMin ^a   Ryu, Seung Hun ^a   Lee, Byeo Ri ^a   Kim, Kyung Hee ^a   Lee, Eunil ^a   Choi, Jaewook ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Artificial light at night; breast cancer; circadian rhythm; light exposure; light pollution

Indexed keywords

MELATONIN;

ADVERSE EFFECTS; BREAST NEOPLASMS; CIRCADIAN RHYTHM; FEMALE; HUMAN; ILLUMINATION; MALE; METABOLISM; NEOPLASMS, RADIATION-INDUCED; OBSERVATIONAL STUDY; PATHOPHYSIOLOGY; PHOTOPERIODICITY; RADIATION RESPONSE; RISK ASSESSMENT; RISK FACTOR; SIGNAL TRANSDUCTION; SLEEP; SLEEP WAKE DISORDERS; SUNLIGHT; TIME FACTOR; WAKEFULNESS;

BREAST NEOPLASMS; CIRCADIAN CLOCKS; CIRCADIAN RHYTHM; FEMALE; HUMANS; LIGHTING; MALE; MELATONIN; NEOPLASMS, RADIATION-INDUCED; OBSERVATIONAL STUDIES AS TOPIC; PHOTOPERIOD; RISK ASSESSMENT; RISK FACTORS; SIGNAL TRANSDUCTION; SLEEP; SLEEP WAKE DISORDERS; SUNLIGHT; TIME FACTORS; WAKEFULNESS;

EID: 84948085785     PISSN: 07420528     EISSN: 15256073     Source Type: Journal    
DOI: 10.3109/07420528.2015.1073158     Document Type: Review

References (100)

1. Auger RR, Burgess HJ, Dierkhising RA, et al. (2011). Light exposure among adolescents with delayed sleep phase disorder: A prospective cohort study. Chronobiol Int. 28:911-20.
2. Bauer SE, Wagner SE, Burch J, et al. (2013). A case-referent study: Light at night and breast cancer risk in Georgia. Int J Health Geogr. 12:23.
3. Benloucif S, Green K, L'Hermite-Balériaux M, et al. (2006). Responsiveness of the aging circadian clock to light. Neurobiol Aging. 27:1870-9.
4. Blask DE. (2009). Melatonin, sleep disturbance and cancer risk. Sleep Med Rev. 13:257-64.
5. Borugian MJ, Gallagher RP, Friesen MC, et al. (2005). Twenty-fourhour light exposure and melatonin levels among shift workers. J Occup Environ Med. 47:1268-75.
6. Bunnell DE, Treiber SP, Phillips NH, et al. (1992). Effects of evening bright light exposure on melatonin, body temperature and sleep. J Sleep Res. 1:17-23.
7. Burgess HJ. (2013). Evening ambient light exposure can reduce circadian phase advances to morning light independent of sleep deprivation. J Sleep Res. 22:83-8.
8. Burke TM, Markwald RR, Chinoy ED, et al. (2013). Combination of light and melatonin time cues for phase advancing the human circadian clock. Sleep. 36:1617-24.
9. Cajochen C, Jewett ME, Dijk DJ. (2003). Human circadian melatonin rhythm phase delay during a fixed sleep-wake schedule interspersed with nights of sleep deprivation. J Pineal Res. 35: 149-57.
10. Canton JL, Smith MR, Choi HS, et al. (2009). Phase delaying the human circadian clock with a single light pulse and moderate delay of the sleep/dark episode: No influence of iris color. J Circadian Rhythms. 7:8.
11. Carrier J, Dumont M. (1995). Sleep propensity and sleep architecture after bright light exposure at three different times of day. J Sleep Res. 4:202-11.
12. Chang AM, Santhi N, St Hilaire M, et al. (2012). Human responses to bright light of different durations. J Physiol. 590: 3103-12.
13. Chang AM, Scheer FA, Czeisler CA, et al. (2013). Direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans depend on prior light history. Sleep. 36: 1239-46.
14. Chang AM, Scheer FA, Czeisler CA. (2011). The human circadian system adapts to prior photic history. J Physiol. 589: 1095-102.
15. Chellappa SL, Steiner R, Oelhafen P, et al. (2013). Acute exposure to evening blue-enriched light impacts on human sleep. J Sleep Res. 22:573-80.
16. Chepesiuk R. (2009). Missing the dark: Health effects of light pollution. Environ Health Perspect. 117:A20-7.
17. Cho JR, Joo EY, Koo DL, et al. (2013). Let there be no light: The effect of bedside light on sleep quality and background electroencephalographic rhythms. Sleep Med. 14:1422-5.
18. Czepita D, Mojsa A, Czepita M, et al. (2012). Myopia and night lighting. Investigations on children with negative family history. Klin Oczna. 114:22-5.
19. Daurat A, Foret J, Benoit O, et al. (2000). Bright light during nighttime: Effects on the circadian regulation of alertness and performance. Biol Signals Recept. 9:309-18.
20. Davis S, Mirick DK, Stevens RG. (2001). Night shift work, light at night, and risk of breast cancer. J Natl Cancer Inst. 93: 1557-62.
21. Davis S, Mirick DK. (2006). Circadian disruption, shift work and the risk of cancer: A summary of the evidence and studies in Seattle. Cancer Causes Control. 17:539-45.
22. Deacon SJ, Arendt J. (1994). Phase-shifts in melatonin, 6-sulphatoxymelatonin and alertness rhythms after treatment with moderately bright light at night. Clin Endocrinol (Oxf). 40: 413-20.
23. Dewan K, Benloucif S, Reid K, et al. (2011). Light-induced changes of the circadian clock of humans: Increasing duration is more effective than increasing light intensity. Sleep. 34:593-9.
24. Dickerman B, Liu J. (2012). Does current scientific evidence support a link between light at night and breast cancer among female night-shift nurses? Review of evidence and implications for occupational and environmental health nurses. Workplace Health Saf. 60:273-81.
25. Dumont M, Benhaberou-Brun D, Paquet J. (2001). Profile of 24-h light exposure and circadian phase of melatonin secretion in night workers. J Biol Rhythms. 16:502-11.
26. Figueiro MG, Bierman A, Plitnick B, et al. (2009). Preliminary evidence that both blue and red light can induce alertness at night. BMC Neurosci. 10:105.
27. Figueiro MG, Rea MS. (2012). Preliminary evidence that light through the eyelids can suppress melatonin and phase shift dim light melatonin onset. BMC Res Notes. 5:221.
28. Foret J, Daurat A, Tirilly G. (1998). Effect of bright light at night on core temperature, subjective alertness and performance as a function of exposure time. Scand J Work Environ Health. 24: 115-20.
29. Foret J, Daurat A, Touitou Y, et al. (1996). The effect on body temperature and melatonin of a 39-h constant routine with two different light levels at nighttime. Chronobiol Int. 13: 35-45.
30. Gangwisch JE. (2014). Invited commentary: Nighttime light exposure as a risk factor for obesity through disruption of circadian and circannual rhythms. Am J Epidemiol. 180:251-3.
31. Gaston KJ, Visser ME, Hölker F. (2015). The biological impacts of artificial light at night: The research challenge. Philos Trans R Soc Lond B Biol Sci. 370:20140133.
32. Gooley JJ, Chamberlain K, Smith KA, et al. (2011). Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans. J Clin Endocrinol Metab. 96:E463-72.
33. Gordijn MC, Beersma DG, Korte HJ, et al. (1999). Effects of light exposure and sleep displacement on dim light melatonin onset. J Sleep Res. 8:163-74.
34. Goulet G, Mongrain V, Desrosiers C, et al. (2007). Daily light exposure in morning-type and evening-type individuals. J Biol Rhythms. 22:151-8.
35. Grundy A, Sanchez M, Richardson H, et al. (2009). Light intensity exposure, sleep duration, physical activity, and biomarkers of melatonin among rotating shift nurses. Chronobiol Int. 26: 1443-61.
36. Haim A, Portnov BA. (2013). Light pollution as a new risk factor for human breast and prostate cancers. Dordrecht, Heidelberg, New York, London: Springer.
37. Haim A, Zubidat AE. (2015). Artificial light at night: melatonin as a mediator between the environment and epigenome. Philos Trans R Soc Lond B Biol Sci. 370:20140121.
38. Harada T. (2004). Effects of evening light conditions on salivary melatonin of Japanese junior high school students. J Circadian Rhythms. 2:4.
39. Hätönen T, Alila-Johansson A, Mustanoja S, et al. (1999). Suppression of melatonin by 2000-Lux light in humans with closed eyelids. Biol Psychiatry. 46:827-31.
40. Hirota N, Sone Y, Tokura H. (2010). Effect of evening exposure to bright or dim light after daytime bright light on absorption of dietary carbohydrates the following morning. J Physiol Anthropol. 29:79-83.
41. Hood B, Bruck D, Kennedy G. (2004). Determinants of sleep quality in the healthy aged: The role of physical, psychological, circadian and naturalistic light variables. Age Ageing. 33:159-65.
42. Hurley S, Goldberg D, Nelson D, et al. (2014). Light at night and breast cancer risk among California teachers. Epidemiology. 25: 697-706.
43. Hurley S, Nelson DO, Garcia E, et al. (2013). A cross-sectional analysis of light at night, neighborhood sociodemographics and urinary 6-sulfatoxymelatonin concentrations: Implications for the conduct of health studies. Int J Health Geogr. 12:39.
44. Juutilainen J, Kumlin T. (2006). Occupational magnetic field exposure and melatonin: Interaction with light-at-night. Bioelectromagnetics. 27:423-6.
45. Kantermann T, Roenneberg T. (2009). Is light-at-night a health risk factor or a health risk predictor? Chronobiol Int. 26:1069-74.
46. Kavcic P, Rojc B, Dolenc-Groselj L, et al. (2011). The impact of sleep deprivation and nighttime light exposure on clock gene expression in humans. Croat Med J. 52:594-603.
47. Kloog I, Haim A, Stevens RG, et al. (2008). Light at night codistributes with incident breast but not lung cancer in the female population of Israel. Chronobiol Int. 25:65-81.
48. Kloog I, Haim A, Stevens RG, et al. (2009). Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men. Chronobiol Int. 26:108-25.
49. Kloog I, Portnov BA, Rennert HS, et al. (2011). Does the modern urbanized sleeping habitat pose a breast cancer risk? Chronobiol Int. 28:76-80.
50. Kloog I, Stevens RG, Haim A, et al. (2010). Nighttime light level codistributes with breast cancer incidence worldwide. Cancer Causes Control. 21:2059-68.
51. Kohsaka M, Kohsaka S, Fukuda N, et al. (2001). Effects of bright light exposure on heart rate variability during sleep in young women. Psychiatry Clin Neurosci. 55:283-4.
52. Komada Y, Tanaka H, Yamamoto Y, et al. (2000). Effects of bright light pre-exposure on sleep onset process. Psychiatry Clin Neurosci. 54:365-6.
53. Kubota T, Uchiyama M, Hirokawa G, et al. (1998). Effects of evening light on body temperature. Psychiatry Clin Neurosci. 52:248-9.
54. Küller R. (2002). The influence of light on circarhythms in humans. J Physiol Anthropol Appl Human Sci. 21:87-91.
55. Lavoie S, Paquet J, Selmaoui B, et al. (2003). Vigilance levels during and after bright light exposure in the first half of the night. Chronobiol Int. 20:1019-38.
56. Li Q, Zheng T, Holford TR, et al. (2010). Light at night and breast cancer risk: Results from a population-based casecontrol study in Connecticut, USA. Cancer Causes Control. 21: 2281-5.
57. Lockley SW, Evans EE, Scheer FA, et al. (2006). Short-wavelength sensitivity for the direct effects of light on alertness, vigilance, and the waking electroencephalogram in humans. Sleep. 29: 161-8.
58. Lushington K, Galka R, Sassi LN, et al. (2002). Extraocular light exposure does not phase shift saliva melatonin rhythms in sleeping subjects. J Biol Rhythms. 17:377-86.
59. Martin JS, Hébert M, Ledoux E, et al. (2012). Relationship of chronotype to sleep, light exposure, and work-related fatigue in student workers. Chronobiol Int. 29:295-304.
60. Martinez-Nicolas A, Madrid JA, Rol MA. (2014). Day-night contrast as source of health for the human circadian system. Chronobiol Int. 31:382-93.
61. McFadden E, Jones ME, Schoemaker MJ, et al. (2014). The relationship between obesity and exposure to light at night: Cross-sectional analyses of over 100 000 women in the Breakthrough Generations Study. Am J Epidemiol. 180:245-50.
62. Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA Group. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement. PLoS Med. 6:e1000097.
63. Morita T, Tokura H. (1996). Effects of lights of different color temperature on the nocturnal changes in core temperature and melatonin in humans. Appl Human Sci. 15:243-6.
64. Nagata C, Nagao Y, Yamamoto S, et al. (2008). Light exposure at night, urinary 6-sulfatoxymelatonin, and serum estrogens and androgens in postmenopausal Japanese women. Cancer Epidemiol Biomarkers Prev. 17:1418-23.
65. Obayashi K, Saeki K, Iwamoto J, et al. (2013a). Exposure to light at night and risk of depression in the elderly. J Affect Disord. 151: 331-6.
66. Obayashi K, Saeki K, Iwamoto J, et al. (2013b). Exposure to light at night, nocturnal urinary melatonin excretion, and obesity/dyslipidemia in the elderly: A cross-sectional analysis of the HEIJO-KYO study. J Clin Endocrinol Metab. 98:337-44.
67. Obayashi K, Saeki K, Iwamoto J, et al. (2014a). Association between light exposure at night and nighttime blood pressure in the elderly independent of nocturnal urinary melatonin excretion. Chronobiol Int. 31:779-86.
68. Obayashi K, Saeki K, Iwamoto J, et al. (2014b). Effect of exposure to evening light on sleep initiation in the elderly: A longitudinal analysis for repeated measurements in home settings. Chronobiol Int. 31:461-7.
69. Obayashi K, Saeki K, Kurumatani N. (2014c). Association between light exposure at night and insomnia in the general elderly population: The HEIJO-KYO cohort. Chronobiol Int. 31:976-82.
70. O'Leary ES, Schoenfeld ER, Stevens RG, et al. (2006). Shift work, light at night, and breast cancer on Long Island, New York. Am J Epidemiol. 164:358-66.
71. Parry BL, Meliska CJ, Sorenson DL, et al. (2010). Increased sensitivity to light-induced melatonin suppression in premenstrual dysphoric disorder. Chronobiol Int. 27:1438-53.
72. Phipps-Nelson J, Redman JR, Schlangen LJ, et al. (2009). Blue light exposure reduces objective measures of sleepiness during prolonged nighttime performance testing. Chronobiol Int. 26: 891-912.
73. Rahman SA, Flynn-Evans EE, Aeschbach D, et al. (2014). Diurnal spectral sensitivity of the acute alerting effects of light. Sleep. 37:271-81.
74. Rahman SA, Marcu S, Shapiro CM, et al. (2011). Spectral modulation attenuates molecular, endocrine, and neurobehavioral disruption induced by nocturnal light exposure. Am J Physiol Endocrinol Metab. 300:E518-27.
75. Reiter RJ, Tan DX, Korkmaz A, et al. (2007). Light at night, chronodisruption, melatonin suppression, and cancer risk: A review. Crit Rev Oncog. 13:303-28.
76. Rüger M, Gordijn MC, Beersma DG, et al. (2003). Acute and phaseshifting effects of ocular and extraocular light in human circadian physiology. J Biol Rhythms. 18:409-19.
77. Rüger M, Gordijn MC, Beersma DG, et al. (2005). Weak relationships between suppression of melatonin and suppression of sleepiness/fatigue in response to light exposure. J Sleep Res. 14: 221-7.
78. Rüger M, Gordijn MC, Beersma DG, et al. (2006). Time-of-daydependent effects of bright light exposure on human psychophysiology: Comparison of daytime and nighttime exposure. Am J Physiol Regul Integr Comp Physiol. 290:R1413-20.
79. Santhi N, Thorne HC, van der Veen DR, et al. (2012). The spectral composition of evening light and individual differences in the suppression of melatonin and delay of sleep in humans. J Pineal Res. 53:47-59.
80. Shanahan TL, Kronauer RE, Duffy JF, et al. (1999). Melatonin rhythm observed throughout a three-cycle bright-light stimulus designed to reset the human circadian pacemaker. J Biol Rhythms. 14:237-53.
81. Skene DJ, Lockley SW, Thapan K, et al. (1999). Effects of light on human circadian rhythms. Reprod Nutr Dev. 39:295-304.
82. St Hilaire MA, Gooley JJ, Khalsa SB, et al. (2012). Human phase response curve to a 1 h pulse of bright white light. J Physiol. 590: 3035-45.
83. Stevens RG, Blask DE, Brainard GC, et al. (2007). Meeting report: The role of environmental lighting and circadian disruption in cancer and other diseases. Environ Health Perspect. 115: 1357-62.
84. Stevens RG, Brainard GC, Blask DE, et al. (2014). Breast cancer and circadian disruption from electric lighting in the modern world. CA Cancer J Clin. 64:207-18.
85. Stevens RG. (2009). Light-at-night, circadian disruption and breast cancer: Assessment of existing evidence. Int J Epidemiol. 38: 963-70.
86. Thessing VC, Anch AM, Muehlbach MJ, et al. (1994). Two- and 4-hour bright-light exposures differentially effect sleepiness and performance the subsequent night. Sleep. 17:140-5.
87. Tzischinsky O, Lavie P. (1997). The effects of evening bright light on next-day sleep propensity. J Biol Rhythms. 12:259-65.
88. van de Werken M, Giménez MC, de Vries B, et al. (2013). Shortwavelength attenuated polychromatic white light during work at night: Limited melatonin suppression without substantial decline of alertness. Chronobiol Int. 30:843-54.
89. Vollmer C, Michel U, Randler C. (2012). Outdoor light at night (LAN) is correlated with eveningness in adolescents. Chronobiol Int. 29:502-8.
90. Wada K, Nagata C, Nakamura K, et al. (2012). Light exposure at night, sleep duration and sex hormone levels in pregnant Japanese women. Endocr J. 59:393-8.
91. Wada K, Nakamura K, Tamai Y, et al. (2013a). Associations of urinary 6-sulfatoxymelatonin with demographics, body mass, sex steroids, and lifestyle factors in preschool Japanese children. Ann Epidemiol. 23:60-5.
92. Wada K, Yata S, Akimitsu O, et al. (2013b). A tryptophan-rich breakfast and exposure to light with low color temperature at night improve sleep and salivary melatonin level in Japanese students. J Circadian Rhythms. 11:4.
93. Wahnschaffe A, Haedel S, Rodenbeck A, et al. (2013). Out of the lab and into the bathroom: Evening short-term exposure to conventional light suppresses melatonin and increases alertness perception. Int J Mol Sci. 14:2573-89.
94. Wallace-Guy GM, Kripke DF, Jean-Louis G, et al. (2002). Evening light exposure: Implications for sleep and depression. J Am Geriatr Soc. 50:738-9.
95. Whittom S, Dumont M, Petit D, et al. (2010). Effects of melatonin and bright light administration on motor and sensory symptoms of RLS. Sleep Med. 11:351-5.
96. Wright Jr KP, Gronfier C, Duffy JF, et al. (2005). Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans. J Biol Rhythms. 20: 168-77.
97. Yang WS, Deng Q, Fan WY, et al. (2014). Light exposure at night, sleep duration, melatonin, and breast cancer: A dose-response analysis of observational studies. Eur J Cancer Prev. 23:269-76.
98. Yokoi M, Aoki K, Shimomura Y, et al. (2003). Effect of bright light on EEG activities and subjective sleepiness to mental task during nocturnal sleep deprivation. J Physiol Anthropol Appl Human Sci. 22:257-63.
99. Yokoi M, Aoki K, Shimomura Y, et al. (2006). Exposure to bright light modifies HRV responses to mental tasks during nocturnal sleep deprivation. J Physiol Anthropol. 25:153-61.
100. Zeitzer JM, Khalsa SB, Boivin DB, et al. (2005). Temporal dynamics of late-night photic stimulation of the human circadian timing system. Am J Physiol Regul Integr Comp Physiol. 289: R839-44.