Efficacy Interactions of PEG-DOX-N-acetyl Glucosamine Prodrug Conjugate for Anticancer Therapy

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 97, Issue , 2015, Pages 454-463

  Pawar, Smita K ^a   Vavia, Pradeep ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Abbreviations NAG N acetyl glucosamine; BSA bovine serum albumin; CON A concanavallin A; DOX doxorubicin; GLUT glucose transporter; MALDI TOF matrix assisted laser diffraction inductively coupled time of flight; PEG polyethylene glycol

Indexed keywords

BOVINE SERUM ALBUMIN; DOXORUBICIN; LECTIN RECEPTOR; MACROGOL; N ACETYLGLUCOSAMINE; ANTINEOPLASTIC AGENT; LECTIN; MACROGOL DERIVATIVE; MICELLE; PRODRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG EFFICACY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; HYDROPHILICITY; IN VITRO STUDY; IN VIVO STUDY; LECTIN BINDING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PROTEIN BINDING; RECEPTOR BINDING ASSAY; SURFACE CHARGE; ZETA POTENTIAL; 3T3 CELL LINE; ANIMAL; CHEMISTRY; METABOLISM; MICELLE; SPECTROFLUOROMETRY;

3T3 CELLS; ACETYLGLUCOSAMINE; ANIMALS; ANTINEOPLASTIC AGENTS; DOXORUBICIN; HUMANS; LECTINS; MICE; MICELLES; MOLECULAR WEIGHT; PARTICLE SIZE; POLYETHYLENE GLYCOLS; PRODRUGS; SPECTROMETRY, FLUORESCENCE;

EID: 84947944488     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.07.019     Document Type: Article

References (40)

1. T. Minko, S.S. Dharap, R.I. Pakunlu, and Y. Wang Molecular targeting of drug delivery systems to cancer Curr. Drug Targets 5 4 2004 389 406
2. Y. Luo, N.J. Bernshaw, Z.R. Lu, J. Kopecek, and G.D. Prestwich Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates Pharm. Res. 19 4 2002 396 402
3. H. Maeda, L.W. Seymour, and Y. Miyamoto Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo Bioconjug. Chem. 3 1992 351 362
4. J.D. Byrne, T. Betancourt, and L.B. Peppas Active targeting schemes for nanoparticle systems in cancer therapeutics Adv. Drug Deliv. Rev. 60 15 2008 1615 1626
5. A. David Carbohydrate-based biomedical copolymers for targeted delivery of anticancer drugs Israel J. Chem. 50 2 2010 204 219
6. G.P. Adams, and L.M. Weiner Monoclonal antibody therapy of cancer Nat. Biotechnol. 23 2005 1147 1157
7. S.S. Dharap, Y. Wang, P. Chandna, J.J. Khandare, B. Qiu, T. Minko, and et al. Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide Proc. Natl. Acad. Sci. USA 102 2005 12962 12967
8. P.K. Dubey, V. Mishra, S. Jain, S. Mahor, and S. Vyas Liposomes modified with cyclic RGD peptide for tumor targeting J. Drug Target. 12 5 2004 257 264
9. C. Mohanty, M. Das, J. Kanwar, and S.K. Sahoo Receptor mediated tumor targeting: an emerging approach for cancer therapy Curr. Drug Deliv. 8 1 2011 45 58
10. R. Duncan The drawing area of polymer therapeutics Nat. Rev. Drug Discovery 2 2003 347 360
11. R. Duncan Polymer conjugates as anticancer nanomedicines Nat. Rev. Cancer 6 2006 688 701
12. K.J. Wu, and R.W. Odom Characterising synthetic polymers by MALDI MS Anal. Chem. News Features 1 1998 456 461
13. J.J. Khandare, A. Mohr, M. Calderon, P. Welker, K. Licha, and R. Haag Structure-biocompatibility relationship of dendritic polyglycerol derivatives Biomaterials 31 15 2010 4268 4277
14. M. Macheda, S. Rogers, and J. Best Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer J. Cell. Physiol. 202 2005 654 662
15. S. Pawar, A. Budhwar, F. Kharas, J. Khandare, and P. Vavia Design, synthesis and evaluation of N-acetyl glucosamine (NAG)-PEG-doxorubicin targeted conjugates for anticancer delivery Int. J. Pharm. 436 1-2 2012 183 193
16. T. Li, H.B. Lee, and K. Park Comparative stereochemical analysis of glucose-binding proteins for rational design of glucose-specific agents J. Biomater. Sci. Polym. Ed. 9 1998 327 344
17. N. Malik, R. Wiwattanapatapee, R. Klopsch, K. Lorenz, H. Frey, and J.W. Weener Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo J Controlled Rel. 65 2000 133 148
18. G.J. Quinlan, G.S. Martin, and T.W. Evans Albumin: biochemical properties and therapeutic potential Hepatology 41 6 2005 1211 1219
19. Y. Qian, X. Zhou, J. Chen, and Y. Zhang Binding of bezafibrate to human serum albumin: insight into the non-covalent interaction of an emerging contaminant with biomacromolecules Molecules 17 2012 6821 6831
20. M.V.R. Rao, M. Atreyi, and M.R. Rajeswari Fluorescence studies on concanavalin-A J. Biosci. 6 6 1984 823 828
21. K. Amin, and R.M. Dannenfelser In vitro hemolysis: guidance for the pharmaceutical scientist J. Pharm. Sci. 95 6 2006 1173 1176
22. J.W. Nah, Y. Jeong, and C.S. Cho Polymeric micelle formation of multiblock copolymer composed of poly(γ-benzyl l-glutamate) and poly(ethylene oxide) Bull. Korean Chem. Soc. 21 4 2000 383 388
23. F. Khan, A. Ahmad, and M.I. Khan Interaction of fusarium solani lectin with monosaccharides and oligosaccharides: a fluorometric study Photochem. Photobiol. 83 2007 966 970
24. K. Cho, X. Wang, S. Nie, Z. Chen, and D.M. Shin Therapeutic nanoparticles for drug delivery in cancer Clin. Cancer Res. 14 2008 1310 1316
25. V.P. Torchilin Targeted pharmaceutical nanocarriers for cancer therapy and imaging AAPS J. 9 2 2007 E128 E143
26. H.F. Oshrat, R. Eva, B. Simon, and A. Yoram Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells Biomacromolecules 9 2008 435 443
27. O.H. Frenkel, N. Debotton, S. Benita, and Y. Altschuler Targeting of nanoparticles to the clathrin-mediated endocytic pathway BBRC 353 2007 26 32
28. T. Min, H. Ye, P. Zhang, J. Liu, C. Zhang, W. Shen, and et al. Water-soluble poly(ethylene glycol) prodrug of pemetrexed: synthesis, characterization, and preliminary cytotoxicity J. Appl. Polym. Sci. 111 2009 444 451
29. O.K. Abou-Zied, and O.I.K. Al-Shihi Characterization of subdomain IIA binding site of human serum albumin in its native, unfolded, and refolded states using small molecular probes J. Am. Chem. Soc. 130 2008 10793 10801
30. M.J. Eftink Fluorescence quenching reactions: probing biological macromolecular structures T.G. Dewey, Biophysical and Biochemical Aspects of Fluorescence Spectroscopy 1991 Plenum Press New York 1 41
31. J.R. Lakowicz Principles of Fluorescence Spectroscopy 1999 Kluwer Academic/Plenum Publishers New York
32. Shuming Nie Understanding and overcoming major barriers in cancer nanomedicine Nanomedicine 5 4 2010 523 528
33. D.C. Doll Oxidative haemolysis after administration of doxorubicin Br. Med. J. (Clin. Res. Ed.) 287 6386 1983 180 181
34. S. Banerjee, N. Aher, R. Patil, and J. Khandare Poly(ethylene glycol)-prodrug conjugates: concept, design and applications J. Drug. Deliv. 2012
35. K.H. Schlick, C.K. Lange, G.D. Gillispie, and M.J. Cloninger Characterization of protein aggregation via intrinsic fluorescence lifetime J. Am. Chem. Soc. 131 46 2009 16608 16609
36. J.J. Kim, and K. Park Glucose-binding property of pegylated concanavalin A Pharm. Res. 18 6 2001 794 799
37. D.M. Chipman, V. Grisaro, and N. Sharon The binding of oligosaccharides containing N-acetylglucosamine and N-acetylmuramic acid to lysozyme. The specificity of binding subsites J. Biol. Chem. 242 1967 4388 4394
38. L. Wei, L. Tiantian, L. Zhilong, and W. Yun Study of the interaction between a water-soluble cationic fluorescent conjugated polymer and bovine serum albumin J. Solution Chem. 2012
39. C. Helm, W. Knoll, and J. Israelachvili Measurement of ligand-receptor interactions Proc. Natl. Acad. Sci. USA 88 1991 8169 8173
40. S.K. Pawar, and P.R. Vavia Glucosamine anchored cancer targeted nano-vesicular drug delivery system of doxorubicin J. Drug Target. 2015 1 12