Overexpression of mutant HSP27 causes axonal neuropathy in mice

Journal of Biomedical Science

Volumn 22, Issue 1, 2015, Pages

  Lee, Jinho ^a   Jung, Sung Chul ^b   Joo, Jaesoon ^a   Choi, Yu Ri ^a,b   Moon, Hyo Won ^a   Kwak, Geon ^a   Yeo, Ha Kyung ^a   Lee, Ji Su ^a   Ahn, Hye Jee ^a   Jung, Namhee ^b   Hwang, Sunhee ^a   Rheey, Jingeun ^c   Woo, So Youn ^b   Kim, Ji Yon ^b   Hong, Young Bin ^c   Choi, Byung Ok ^a,c  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Ewha Womans University School of Medicine   (South Korea)

^c Samsung Medical Center   (South Korea)

Author keywords

Axonopathy; Charcot Marie Tooth disease (CMT); Distal hereditary motor neuropathy (dHMN); Heat shock 27 kDa protein 1 (HSP27 or HSPB1); Magnetic resonance image (MRI); Mouse model

Indexed keywords

HEAT SHOCK PROTEIN 27; MESSENGER RNA; NEUROFILAMENT PROTEIN; TUBULIN; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, MOUSE; TUMOR PROTEIN;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXONAL NEUROPATHY; BEHAVIORAL SCIENCE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DEMYELINATION; ELECTRON MICROSCOPY; FEMALE; GENE OVEREXPRESSION; HSP27 GENE; IMMUNOHISTOCHEMISTRY; LIPID COMPOSITION; MOTOR DYSFUNCTION; MOUSE; MOUSE MODEL; MUSCLE ACTION POTENTIAL; NERVE CELL LESION; NERVE CONDUCTION VELOCITY; NEUROPATHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL NEUROPATHY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ROTAROD TEST; SCIATIC NERVE; SURAL NERVE; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; GENETICS; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; METABOLISM; MOTONEURON; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; SPINAL MUSCULAR ATROPHY;

ANIMALS; CHARCOT-MARIE-TOOTH DISEASE; DISEASE MODELS, ANIMAL; HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; MUTATION; NEOPLASM PROTEINS; PERIPHERAL NERVOUS SYSTEM DISEASES;

EID: 84947935023     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/s12929-015-0154-y     Document Type: Article

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