Pallidal Deep Brain Stimulation in DYT6: Significant Long-Term Improvement of Dystonia and Disability

Movement Disorders Clinical Practice

Volumn 1, Issue 2, 2014, Pages 118-120

  França, Sara ^a,b   Massano, João ^a,b,c   Linhares, Paulo ^a,b   Rosas, Maria José ^a   Volkmann, Jens ^d  

^a Universidade do Porto   (Portugal)

^b University of Porto   (Portugal)

^c HOSPITAL PEDRO HISPANO   (Portugal)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

Author keywords

cervical dystonia; deep brain stimulation; DYT6; generalized dystonia; globus pallidus; primary dystonia; THAP1 gene

Indexed keywords

BACLOFEN; LEVODOPA; TRIHEXYPHENIDYL;

ADULT; ARTICLE; BRAIN DEPTH STIMULATION; CASE REPORT; CLINICAL ARTICLE; DISABILITY; DYSTONIA; FEMALE; FRAMESHIFT MUTATION; HUMAN; LONG TERM CARE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SPEECH DISORDER; STEREOTAXIC SURGERY; X-RAY COMPUTED TOMOGRAPHY;

EID: 84947863179     PISSN: None     EISSN: 23301619     Source Type: Journal    
DOI: 10.1002/mdc3.12019     Document Type: Article

References (5)

1. Fuchs T, Gavarini S, Saunders-Pullman R, et al. Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia. Nat Genet 2009;41:286–288.
2. Zittel S, Moll CK, Bruggemann N, et al. Clinical neuroimaging and electrophysiological assessment of three DYT6 dystonia families. Mov Disord 2010;25:2405–2412.
3. Groen JL, Ritz K, Contarino MF, et al. DYT6 dystonia: mutation screening, phenotype, and response to deep brain stimulation. Mov Disord 2010;25:2420–2427.
4. Jech R, Bares M, Krepelova A, et al. DYT 6 – a novel THAP1 mutation with excellent effect on pallidal DBS. Mov Disord 2011;26:924–925.
5. Panov F, Tagliati M, Alterman R, et al. Pallidal deep brain stimulation for DYT6 dystonia. J Neurol Neurosurg Psychiatry 2012;83:182–187.