Comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2"

Science Translational Medicine

Volumn 7, Issue 314, 2015, Pages

  Vassalli, Anne ^a   Li, Sha ^a   Tafti, Mehdi ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DYNORPHIN; HYPOCRETIN RECEPTOR 2 ANTIBODY; INFLUENZA NUCLEOPROTEIN; INFLUENZA VACCINE; NUCLEOPROTEIN; OREXIN 2 RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN; CORE PROTEIN; OREXIN RECEPTOR; RNA BINDING PROTEIN; VIRUS ANTIBODY;

ARTICLE; BINDING AFFINITY; BRAIN CELL; CELL MEDIATED CYTOTOXICITY; CELLULAR DISTRIBUTION; CROSS REACTION; GENE; GENE FREQUENCY; GENE MUTATION; HCRTR2 GENE; IMMUNOREACTIVITY; NARCOLEPSY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; HUMAN; IMMUNOLOGY;

ANTIBODIES, VIRAL; CROSS REACTIONS; HUMANS; OREXIN RECEPTORS; RNA-BINDING PROTEINS; VIRAL CORE PROTEINS;

EID: 84947764326     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aad2353     Document Type: Article

References (9)

1. S. S. Ahmed, W. Volkmuth, J. Duca, L. Corti, M. Pallaoro, A. Pezzicoli, A. Karle, F. Rigat, R. Rappuoli, V. Narasimhan, I. Julkunen, A. Vuorela, O. Vaarala, H. Nohynek, F. L. Pasini, E. Montomoli, C. Trombetta, C. M. Adams, J. Rothbard, L. Steinman, Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2. Sci. Transl. Med. 7, 294ra105 (2015).
2. J. N. Marcus, C. J. Aschkenasi, C. E. Lee, R. M. Chemelli, C. B. Saper, M. Yanagisawa, J. K. Elmquist, Differential expression of orexin receptors 1 and 2 in the rat brain. J. Comp. Neurol. 435, 6-25 (2001).
3. L. Lin, J. Faraco, R. Li, H. Kadotani, W. Rogers, X. Lin, X. Qiu, P. J. de Jong, S. Nishino, E. Mignot, The sleep disorder canine narcolepsy is caused by amutation in the hypocretin (orexin) receptor 2 gene. Cell 98, 365-376 (1999).
4. J. T. Willie, R. M. Chemelli, C. M. Sinton, S. Tokita, S. C. Williams, Y. Y. Kisanuki, J. N. Marcus, C. Lee, J. K. Elmquist, K. A. Kohlmeier, C. S. Leonard, J. A. Richardson, R. E. Hammer, M. Yanagisawa, Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: Molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron 38, 715-730 (2003).
5. C. Peyron, J. Faraco, W. Rogers, B. Ripley, S. Overeem, Y. Charnay, S. Nevsimalova, M. Aldrich, D. Reynolds, R. Albin, R. Li, M. Hungs, M. Pedrazzoli, M. Padigaru, M. Kucherlapati, J. Fan, R. Maki, G. J. Lammers, C. Bouras, R. Kucherlapati, S. Nishino, E. Mignot, A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat. Med. 6, 991-997 (2000).
6. T. C. Thannickal, R. Y. Moore, R. Nienhuis, L. Ramanathan, S. Gulyani, M. Aldrich, M. Cornford, J. M. Siegel, Reduced number of hypocretin neurons in human narcolepsy. Neuron 27, 469-474 (2000).
7. S. Nishino, B. Ripley, S. Overeem, G. J. Lammers, E. Mignot, Hypocretin (orexin) deficiency in human narcolepsy. Lancet 355, 39-40 (2000).
8. A. Yamanaka, S. Tabuchi, T. Tsunematsu, Y. Fukazawa, M. Tominaga, Orexin directly excites orexin neurons through orexin 2 receptor. J. Neurosci. 30, 12642-12652 (2010).
9. B. Ripley, N. Fujiki, M. Okura, E. Mignot, S. Nishino, Hypocretin levels in sporadic and familial cases of canine narcolepsy. Neurobiol. Dis. 8, 525-534 (2001)