Genome-wide redistribution of H3K27me3 is linked to genotoxic stress and defective growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 46, 2015, Pages E6339-E6348

  Basenko, Evelina Y ^a   Sasaki, Takahiko ^a   Ji, Lexiang ^a   Prybol, Cameron J ^a   Burckhardt, Rachel M ^a   Schmitz, Robert J ^b   Lewis, Zachary A ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b University of Georgia   (United States)

Author keywords

Genotoxic stress; H3K27me3; H3k9me3; Heterochromatin; Polycomb

Indexed keywords

BLEOMYCIN; CAMPTOTHECIN; CISPLATIN; ETOPOSIDE; FUNGAL PROTEIN; GENOMIC DNA; HISTONE; HISTONE H2A; HISTONE H2A GAMMA; HISTONE H3K27; HISTONE LYSINE METHYLTRANSFERASE; HISTONE LYSINE METHYLTRANSFERASE 1; LYSINE DERIVATIVE; MESYLIC ACID METHYL ESTER; MITOMYCIN; POLYCOMB REPRESSIVE COMPLEX 2; RIBOSOME RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; HETEROCHROMATIN; MULTIENZYME COMPLEX; PROTEIN METHYLTRANSFERASE;

ALLELE; CHROMATIN ASSEMBLY AND DISASSEMBLY; COLONY FORMING UNIT; CONFERENCE PAPER; CONSTITUTIVE HETEROCHROMATIN; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; DNA REPLICATION; DOWN REGULATION; EMBRYO DEVELOPMENT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FUNGAL DEVELOPMENT; FUNGAL GENETICS; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; GENE ISOLATION; GENE MUTATION; GENE REPRESSION; GENE SILENCING; GENETIC LINKAGE; GENETIC PARAMETERS; GENOME ANALYSIS; GENOME WIDE REDISTRIBUTION; GENOMIC INSTABILITY; GENOTOXICITY; GENOTYPE; GROWTH INHIBITION; GROWTH RATE; HETEROCHROMATIN; HETEROKARYON; HISTONE METHYLATION; HUMAN; HUMAN CELL; MISSENSE MUTATION; NEUROSPORA CRASSA; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; PRIORITY JOURNAL; PROGENY; PROTEIN DEPLETION; RNA SEQUENCE; RNA SYNTHESIS; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; UPREGULATION; FUNGAL GENOME; GENETICS; METABOLISM; METHYLATION;

DNA DAMAGE; FUNGAL PROTEINS; GENOME, FUNGAL; HETEROCHROMATIN; HISTONES; METHYLATION; MULTIENZYME COMPLEXES; NEUROSPORA CRASSA; PROTEIN METHYLTRANSFERASES;

EID: 84947466083     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1511377112     Document Type: Article

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