Methylation of HOXA9 and ISL1 predicts patient outcome in high-grade non-invasive bladder cancer

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Kitchen, Mark O ^a,b   Bryan, Richard T ^c   Haworth, Kim E ^a   Emes, Richard D ^d   Luscombe, Christopher ^b   Gommersall, Lyndon ^b   Cheng, K K ^c   Zeegers, Maurice P ^e   James, Nicholas D ^f   Devall, Adam J ^c   Fryer, Anthony A ^a   Farrell, William E ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b UNIVERSITY HOSPITALS OF NORTH MIDLANDS NHS TRUST   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; TRANSCRIPTION FACTOR HOXA9; HOMEODOMAIN PROTEIN; INSULIN GENE ENHANCER BINDING PROTEIN ISL-1; LIM HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR; TUMOR MARKER;

ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER MORTALITY; CANCER PROGNOSIS; CANCER RECURRENCE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ACTIVITY; DNA METHYLATION; GENE; GENE EXPRESSION; GENE SEQUENCE; HISTOPATHOLOGY; HOXA9 GENE; HUMAN; HUMAN TISSUE; ISL1 GENE; METASTASIS; NKX6 2 GENE; NON MUSCLE INVASIVE BLADDER CANCER; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PROMOTER REGION; PYROSEQUENCING; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SPAG6 GENE; TUMOR INVASION; ZIC1 GENE; ZNF154 GENE; AGED; BLADDER TUMOR; GENETICS; PATHOLOGY; PROGNOSIS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; DNA METHYLATION; HOMEODOMAIN PROTEINS; HUMANS; LIM-HOMEODOMAIN PROTEINS; NEOPLASM GRADING; PROGNOSIS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS; URINARY BLADDER NEOPLASMS;

EID: 84947421665     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137003     Document Type: Article

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