Type specific Real time PCR for detection of human herpes virus 6 in schizophrenia and bipolar patients: A case control study

BMC Psychiatry

Volumn 15, Issue 1, 2015, Pages

  Yavarian, Jila ^a   Malekshahi, Somaye Shatizadeh ^a   Yavarian, Roya ^b   Yazdani, Shaghayegh ^a   Janani, Leila ^c   Jandaghi, Nazanin Zahra Shafiei ^a   Kiani, Seyed Jalal ^a   Ahamadkhaniha, Hamid Reza ^d  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b URMIA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bipolar disorder; HHV 6; Schizophrenia

Indexed keywords

ADULT; ARTICLE; BIPOLAR DISORDER; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PREVALENCE; REAL TIME POLYMERASE CHAIN REACTION; SCHIZOPHRENIA; VIRUS DETECTION; VIRUS TYPING; ISOLATION AND PURIFICATION; MONONUCLEAR CELL; NORMAL HUMAN; PROCEDURES; PSYCHOLOGY; ROSEOLOVIRUS INFECTIONS; VIROLOGY;

VIRUS DNA;

ADULT; BIPOLAR DISORDER; CASE-CONTROL STUDIES; DNA, VIRAL; FEMALE; HEALTHY VOLUNTEERS; HERPESVIRUS 6, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; REAL-TIME POLYMERASE CHAIN REACTION; ROSEOLOVIRUS INFECTIONS; SCHIZOPHRENIA;

EID: 84947346836     PISSN: None     EISSN: 1471244X     Source Type: Journal    
DOI: 10.1186/s12888-015-0662-z     Document Type: Article

References (33)

1. Yolken RH, Torrey EF. Viruses, schizophrenia, and bipolar disorder. Clin Microbiol Rev. 1995;8(1):131-45.
2. Niebuhr DW, Millikan AM, Yolken R, Li Y, Weber NS. Results from a hypothesis generating case-control study: herpes family viruses and schizophrenia among military personnel. Schizophrenia Bull. 2008;34:1182-8.
3. Hannachi N, El Kissi Y, Samoud S, Nakhli J, Letaief L, Gaabout S, et al. High prevalence of Human Herpesvirus 8 in schizophrenic patients. Psychiatry Res. 2014;15:192-7.
4. Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenegger S, Kaplan M, et al. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science. 1986;234:596-601.
5. Agut H. Puzzles concerning the pathogenicity of human herpesvirus 6. N Engl J Med. 1993;329:203-4.
6. Campadelli-Fiume G, Mirandola P, Menotti L. Human herpesvirus 6: an emerging pathogen. EID. 1999;5:353-66.
7. Pruksananonda P, Hall CB, Insel RA, McIntyre K, Pellett PE, Long CE, et al. Primary human herpesvirus 6 infection in young children. N Engl J Med. 1992;326:1445-50.
8. Fotheringham J, Donati D, Akhyani N, Fogdell-Hahn A, Vortmeyer A, Heiss JD, et al. Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS Med. 2007;4:e180.
9. Yamanish K, Okuno T, Shiraki K, Takahashi M, Kondo T, Asano Y, et al. Identification of human herpesvirus-6 as the causal agent of exanthema subitum. Lancet. 1988;1:1065-7.
10. Mamishi S, Kamrani L, Mohammadpour M, Yavarian J. Prevalence of HHV-6 in cerebrospinal fluid of children younger than 2 years of age with febrile convulsion. Iran J Microbiol. 2014;6:87-90.
11. Theodore WH, Shinnar S, Gaillard WD, Wainwright MS, Epstein L, Jacobson S. Human herpes virus 6B: a possible role in epilepsy? Epilepsia. 2008;49: 1828-37.
12. Reynaud JM, Horvat B. Human herpesvirus 6 and Neuroinflammation. ISRN Virol. 2013;Article ID 834890:1-11.
13. Blauvelt A. Skin diseases associated with human herpesvirus 6, 7, and 8 infection. JIDSP. 2001;6:197-202.
14. Association AP. Diagnostic and statistical manual of mental disorders: DSMIV-TR®: American Psychiatric Pub. 2000.
15. Gibbon M, Spitzer RL, First MB. User's guide for the structured clinical interview for DSM-IV axis II personality disorders: SCID-II: American Psychiatric Pub. 1997.
16. Caserta MT, Hall CB, Schnabel K, Lofthus G, Marino A, Shelley L, et al. Diagnostic assays for active infection with human herpesvirus 6 (HHV-6). J clin virol. 2010;48:55-7.
17. Achour A, Boutolleau D, Slim A, Agut H, Gautheret-Dejean A. Human herpesvirus-6 (HHV-6) DNA in plasma reflects the presence of infected blood cells rather than circulating viral particles. J clin virol. 2007;38:280-5.
18. Duggal S, Bhatia NK, Duggal AK, Bhatia MS. Viral infections and schizophrenia. Delhi Psych J. 2008;11:190-6.
19. Roizman B, Carmichael LE, Deinhardt F, de-The G, Nahmias AJ, Plowright W, et al. Herpesviridae: definition, provisional nomenclature, and taxonomy. Intervirol. 1981;16:201-17.
20. Nicolson GL, Haier J. Role of chronic bacterial and viral infections in neurodegenerative, neurobehavioural, psychiatric, autoimmune and fatiguing illnesses: Part 2. BJMP. 2010;3:301-11.
21. Tanaka-Taya K, Kondo T, Mukai T, Miyoshi H, Yamamoto Y, Okada S, et al. Seroepidemiological study of human herpesvirus-6 and-7 in children of different ages and detection of these two viruses in throat swabs by polymerase chain reaction. J Med Virol. 1996;48:88-94.
22. Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. Clin Microbiol Rev. 1997;10:521-67.
23. Nitsche A, Muller CW, Radonic A, Landt O, Ellerbrok H, Pauli G, et al. Human herpesvirus 6A DNA is detected frequently in plasma but rarely in peripheral blood leukocytes of patients after bone marrow transplantation. J Infect Dis. 2001;183:130-3.
24. Luppi M, Barozzi P, Maiorana A, Marasca R, Trovato R, Fano R, et al. Human herpesvirus-6: a survey of presence and distribution of genomic sequences in normal brain and neuroglial tumors. J Med Virol. 1995;47:105-11.
25. Chan PK, Ng HK, Hui M, Ip M, Cheung JL, Cheng AF. Presence of human herpesviruses 6, 7, and 8 DNA sequences in normal brain tissue. J Med Virol. 1999;59:491-5.
26. Chan PK, Ng HK, Hui M, Cheng AF. Prevalence and distribution of human herpesvirus 6 variants A and B in adult human brain. J Med Virol. 2001;64: 42-6.
27. Cuomo L, Trivedi P, Cardillo MR, Gagliardi FM, Vecchione A, Caruso R, et al. Human herpesvirus 6 infection in neoplastic and normal brain tissue. J Med Virol. 2001;63:45-51.
28. Donati D, Akhyani N, Fogdell-Hahn A, Cermelli C, Cassiani-Ingoni R, Vortmeyer A, et al. Detection of human herpesvirus-6 in mesial temporal lobe epilepsy surgical brain resections. Neurology. 2003;61:1405-11.
29. De Bolle L, Naesens L, De Clercq E. Update on human herpesvirus 6 biology, clinical features, and therapy. Clin Microbiol Rev. 2005;18:217-45.
30. Fukuda R, Sasaki T, Kunugi H, Nanko S. No changes in paired viral antibody titers during the course of acute schizophrenia. Neuropsychobiology. 1999; 40:57-62.
31. Bradbury TN, Miller GA. Season of birth in schizophrenia: a review of evidence, methodology and etiology. Psychol Bull. 1985;98:569-94.
32. Boyd JH, Pulver AE, Stewart W. Season of birth: schizophrenia and bipolar disorder. Schizophr Bull. 1986;12:173-85.
33. Yolken R. Viruses and schizophrenia: a focus on herpes simplex virus. Herpes. 2004;11:83-8