Poor glycemic control associates with high intravitreal angiopoietin-2 levels in patients with diabetic retinopathy

Acta Ophthalmologica

Volumn 93, Issue 6, 2015, Pages e515-e516

  Tuuminen, Raimo ^a   Haukka, Jari ^b   Loukovaara, Sirpa ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 2; HEMOGLOBIN A1C; VASCULOTROPIN; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

BODY MASS; DIABETES MELLITUS; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE DURATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCEMIC CONTROL; HUMAN; LETTER; PRIORITY JOURNAL; PROTEIN DETERMINATION; ADULT; AGED; FEMALE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; MALE; METABOLISM; MIDDLE AGED; VERY ELDERLY; VITRECTOMY; VITREOUS BODY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANGIOPOIETIN-2; BLOOD GLUCOSE; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERGLYCEMIA; MALE; MIDDLE AGED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITRECTOMY; VITREOUS BODY; YOUNG ADULT;

EID: 84947048299     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/aos.12401     Document Type: Letter

References (5)

1. Hammes HP, Feng Y, Pfister F, &, Brownlee M, (2011): Diabetic retinopathy: targeting vasoregression. Diabetes 60: 9-16.
2. Klaassen I, Van Noorden CJ, &, Schlingemann RO, (2013): Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions. Prog Retin Eye Res 34: 19-48.
3. Loukovaara S, Robciuc A, Holopainen JM, et al., (2013): Ang-2 upregulation correlates with increased levels of MMP-9, VEGF, EPO and TGFbeta1 in diabetic eyes undergoing vitrectomy. Acta Ophthalmol 91: 531-539.
4. The Diabetes Control and Complications Trials Research Group (1995): The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trial. Diabetes 44: 968-983.
5. Zehetner C, Kirchmair R, Kralinger M, &, Kieselbach G, (2013): Correlation of vascular endothelial growth factor plasma levels and glycemic control in patients with diabetic retinopathy. Acta Ophthalmol 91: e470-e473.