Alzheimer disease: APOE∗ε 4-associated increase in AD risk linked to phospholipid dysregulation

Nature Reviews Neurology

Volumn 11, Issue 11, 2015, Pages 610-

  Malkki, Hemi ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL PHOSPHATE; SYNAPTOJANIN; APOLIPOPROTEIN E4; PHOSPHOLIPID;

ALZHEIMER DISEASE; APOLIPOPROTEIN E EPSILON4 GENE; CAUSE OF DEATH; DEMENTIA; DNA MODIFICATION; GENE; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; LIPIDOSIS; MEMORY DISORDER; MOLECULAR DYNAMICS; NONHUMAN; NOTE; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; ANIMAL; COGNITIVE DEFECT; COMPLICATION; FEMALE; MALE; METABOLISM;

ALZHEIMER DISEASE; ANIMALS; APOLIPOPROTEIN E4; COGNITION DISORDERS; FEMALE; HUMANS; MALE; PHOSPHOLIPIDS;

EID: 84947040610     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2015.180     Document Type: Note

References (2)

1. Zhu, L. et al. Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimeŕs disease pathogenesis. Proc. Natl Acad. Sci. USA doi:10.1073/pnas.1510011112
2. Mapstone, M. et al. Plasma phospholipids identify antecedent memory impairment in older adults. Nat. Med. 20, 415-418 (2014).