Variation in the contents of sepsis bundles and quality measures: A systematic review

Annals of the American Thoracic Society

Volumn 12, Issue 11, 2015, Pages 1676-1684

  Kramer, Rachel D ^a   Cooke, Colin R ^b   Liu, Vincent ^c   Miller, Russell R ^d,e   Iwashyna, Theodore J ^b,f,g  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c KAISER PERMANENTE   (United States)

^d INTERMOUNTAIN MEDICAL CENTER   (United States)

^e UNIVERSITY OF UTAH   (United States)

^f VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^g MONASH UNIVERSITY   (Australia)

Author keywords

Bundles; Guidelines; Quality improvement; Quality metrics; Sepsis

Indexed keywords

ANTIBIOTIC AGENT; LACTIC ACID; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; BLOOD CULTURE; CENTRAL VENOUS PRESSURE; HUMAN; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; MEAN ARTERIAL PRESSURE; RESUSCITATION; REVIEW; SEPSIS; SHORT COURSE THERAPY; SYSTEMATIC REVIEW; TOTAL QUALITY MANAGEMENT; URINE VOLUME; ECONOMICS; LENGTH OF STAY; MORTALITY; PROTOCOL COMPLIANCE; SEVERITY OF ILLNESS INDEX; STANDARDS; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; GUIDELINE ADHERENCE; HUMANS; LENGTH OF STAY; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 84946780329     PISSN: 23256621     EISSN: None     Source Type: Journal    
DOI: 10.1513/AnnalsATS.201503-163BC     Document Type: Review

References (31)

1. Liu V, Escobar GJ, Greene JD, Soule J, Whippy A, Angus DC, Iwashyna TJ. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA 2014;312:90-92.
2. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med 2012;40:754-761.
3. Rhee C, Murphy MV, Li L, Platt R, Klompas M; Centers for Disease Control and Prevention Epicenters Program. Comparison of trends in sepsis incidence and coding using administrative claims versus objective clinical data. Clin Infect Dis 2015;60:88-95.
4. Torio CM, Andrews RM. National inpatient hospital costs: the most expensive conditions by payer, 2011: statistical brief #160. Healthcare Cost and Utilization Project (HCUP) Statistical Briefs [Internet]. Rockville (MD): Agency for Health Care Policy and Research (US); 2006-2013.
5. Centers for Medicare and Medicaid Services. New Medicare data available to increase transparency on hospital utilization [Internet]. [accessed 2015 June 29]. Available from: http://www.cms.gov/
6. Newsroom/MediaReleaseDatabase/Fact-sheets/2015-Fact-sheets-items/2015-06-01.html.
7. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, Suppes R, Feinstein D, Zanotti S, Taiberg L, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006; 34:1589-1596.
8. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29:1303-1310.
9. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, et al.; Surviving Sepsis Campaign. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med 2010;38: 367-374.
10. Iwashyna TJ, Odden A, Rohde J, Bonham C, Kuhn L, Malani P, Chen L, Flanders S. Identifying patients with severe sepsis using administrative claims: patient-level validation of the angus implementation of the international consensus conference definition of severe sepsis. Med Care 2014;52:e39-e43.
11. Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, et al.; ProCESS Investigators. A randomized trial of protocol-based care for early septic shock. N Engl J Med 2014;370:1683-1693.
12. Peake SL, Delaney A, Bailey M, Bellomo R, Cameron PA, Cooper DJ, Higgins AM, Holdgate A, Howe BD, Webb SA, et al.; ARISE Investigators; ANZICS Clinical Trials Group. Goal-directed resuscitation for patients with early septic shock. N Engl J Med 2014;371:1496-1506.
13. Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, et al.; ProMISe Trial Investigators. Trial of early, goal-directed resuscitation for septic shock. N Engl J Med 2015;372:1301-1311.
14. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, et al.; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med 2013;41:580-637.
15. Ferrer R, Artigas A, Levy MM, Blanco J, González-Dí az G, Garnacho-Montero J, Ibáñez J, Palencia E, Quintana M, de la Torre-Prados MV; Edusepsis Study Group. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA 2008;299:2294-2303.
16. Shiramizo SC, Marra AR, Durão MS, Paes  T, Edmond MB, Pavão dos Santos OF. Decreasing mortality in severe sepsis and septic shock patients by implementing a sepsis bundle in a hospital setting. PLoS One 2011;6:e26790.
17. Miller RR III, Dong L, Nelson NC, Brown SM, Kuttler KG, Probst DR, Allen TL, Clemmer TP; Intermountain Healthcare Intensive Medicine Clinical Program. Multicenter implementation of a severe sepsis and septic shock treatment bundle. Am J Respir Crit Care Med 2013;188:77-82.
18. Whippy A, Skeath M, Crawford B, Adams C, Marelich G, Alamshahi M, Borbon J. Kaiser Permanente's performance improvement system, part 3: multisite improvements in care for patients with sepsis. Jt Comm J Qual Patient Saf 2011;37:483-493.
19. Nguyen HB, Corbett SW, Steele R, Banta J, Clark RT, Hayes SR, Edwards J, Cho TW, Wittlake WA. Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med 2007;35:1105-1112.
20. Robson WP, Daniel R. The Sepsis Six: helping patients to survive sepsis. Br J Nurs 2008;17:16-21.
21. National Quality Forum. 0500 Severe sepsis and septic shock: management bundle (composite measure) [Internet]. [accessed 2015 May 12]; Available from: http://www.qualityforum.org/QPS/0500.
22. Michigan Health and Hospital Association. MHA Keystone Center member guidebook [Internet]. [accessed 2015 April 5]; Available from: http://www.mhakeystonecenter.org/documents/member-guidebook.pdf.
23. Crowe CA, Mistry CD, Rzechula K, Kulstad CE. Evaluation of a modified early goal-directed therapy protocol. Am J Emerg Med 2010;28:689-693.
24. Kramer RD, Cooke CR, Liu V, Miller RR, Iwashnya TJ. What's in a sepsis bundle? Descriptive comparison of sepsis quality measures. Presented at the American Thoracic Society 2015 International Conference, Denver, CO, May 20, 2015.
25. Harhay MO, Wagner J, Ratcliffe SJ, Bronheim RS, Gopal A, Green S, Cooney E, Mikkelsen ME, Kerlin MP, Small DS, et al. Outcomes and statistical power in adult critical care randomized trials. Am J Respir Crit Care Med 2014;189:1469-1478.
26. Centers for Medicare and Medicaid Services. Section 2.2-Severe Sepsis and Septic Shock (SEP). Specifications manual for national hospital inpatient quality measures [Internet]. [updated 2015 May 29; accessed 2015 June 2]. Available from: https://www.qualitynet.org/dcs/ContentServer?pagename=QnetPublic/Search/SearchResults&keywords=severe+sepsis+and+septic+shock&rowNum=21.
27. Feinstein AR, Sosin DM, Wells CK. The Will Rogers phenomenon: stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer. N Engl J Med 1985;312: 1604-1608.
28. Cooke CR, Iwashyna TJ. Sepsis mandates: improving inpatient care while advancing quality improvement. JAMA 2014;312: 1397-1398.
29. Kahn JM, Gould MK, Krishnan JA, Wilson KC, Au DH, Cooke CR, Douglas IS, Feemster LC, Mularski RA, Slatore CG, et al.; ATS Ad Hoc Committee on the Development of Performance Measures from ATS Guidelines. An official American thoracic society workshop report: developing performance measures from clinical practice guidelines. Ann Am Thorac Soc 2014;11: S186-S195.
30. Kitson AL, Rycroft-Malone J, Harvey G, McCormack B, Seers K, Titchen A. Evaluating the successful implementation of evidence into practice using the PARiHS framework: theoretical and practical challenges. Implement Sci 2008;3:1.
31. Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework. Am J Public Health 1999;89:1322-1327.