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Volumn 13, Issue 5, 2015, Pages 558-576

The involvement of TNF-α in cognitive dysfunction associated with major depressive disorder: An opportunity for domain specific treatments

Author keywords

Antidepressant; Cytokines; Depression; Inflammation; TNF ; TNF antagonists

Indexed keywords

ADALIMUMAB; CASPASE 3; CASPASE 8; CERTOLIZUMAB PEGOL; CXCL13 CHEMOKINE; ETANERCEPT; FLUOXETINE; GAMMA INTERFERON; GOLIMUMAB; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PAROXETINE; SECONDARY LYMPHOID TISSUE CHEMOKINE; SERTRALINE; STRESS ACTIVATED PROTEIN KINASE; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1; TUMOR NECROSIS FACTOR;

EID: 84946713014     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X13666150630171433     Document Type: Article
Times cited : (112)

References (150)
  • 1
    • 84878757053 scopus 로고    scopus 로고
    • Cognitive deficits andfunctional outcomes in major depressive disorder: Determinants,substrates, and treatment interventions
    • McIntyre, R.S.; Cha, D.S.; Soczynska, J.K. Cognitive deficits andfunctional outcomes in major depressive disorder: determinants,substrates, and treatment interventions. Depress. Anxiety, 2013,30(6), 515-527. http://dx.doi.org/10.1002/da.22063
    • (2013) Depress. Anxiety , vol.30 , Issue.6 , pp. 515-527
    • McIntyre, R.S.1    Cha, D.S.2    Soczynska, J.K.3
  • 2
    • 75849155537 scopus 로고    scopus 로고
    • A meta-analysis ofcytokines in major depression
    • Dowlati, Y.; Herrmann, N.; Swardfager, W. A meta-analysis ofcytokines in major depression. Biol. Psychiatry, 2010, 67(5), 446-457. http://dx.doi.org/10.1016/j.biopsych.2009.09.033
    • (2010) Biol. Psychiatry , vol.67 , Issue.5 , pp. 446-457
    • Dowlati, Y.1    Herrmann, N.2    Swardfager, W.3
  • 3
    • 84896055808 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors inmood disorders, schizophrenia, and cognitive impairment: Asystematic review of biomarker studies
    • Stuart, M.J.; Baune, B.T. Chemokines and chemokine receptors inmood disorders, schizophrenia, and cognitive impairment: Asystematic review of biomarker studies. Neurosci. Biobehav. Rev., 2014, 42C, 93-115. http://dx.doi.org/10.1016/j.neubiorev.2014.02.001
    • (2014) Neurosci. Biobehav. Rev. , vol.42 , pp. 93-115
    • Stuart, M.J.1    Baune, B.T.2
  • 4
    • 84876670027 scopus 로고    scopus 로고
    • The neuroprogressivenature of major depressive disorder: Pathways to disease evolutionand resistance, and therapeutic implications
    • Moylan, S.; Maes, M.; Wray, N.R.; Berk, M. The neuroprogressivenature of major depressive disorder: pathways to disease evolutionand resistance, and therapeutic implications. Mol. Psychiatry, 2013,18(5), 595-606. http://dx.doi.org/10.1038/mp.2012.33
    • (2013) Mol. Psychiatry , vol.18 , Issue.5 , pp. 595-606
    • Moylan, S.1    Maes, M.2    Wray, N.R.3    Berk, M.4
  • 5
    • 84901253775 scopus 로고    scopus 로고
    • Dynamic microglial alterationsunderlie stress-induced depressive-like behavior and suppressedneurogenesis
    • Kreisel, T.; Frank, M.G.; Licht, T. Dynamic microglial alterationsunderlie stress-induced depressive-like behavior and suppressedneurogenesis. Mol. Psychiatry, 2014, 19(6), 699-709. http://dx.doi.org/10.1038/mp.2013.155
    • (2014) Mol. Psychiatry , vol.19 , Issue.6 , pp. 699-709
    • Kreisel, T.1    Frank, M.G.2    Licht, T.3
  • 6
    • 84893462851 scopus 로고    scopus 로고
    • Role ofimmune-inflammatory and oxidative and nitrosative stresspathways in the etiology of depression: Therapeutic implications
    • Anderson, G.; Berk, M.; Dean, O.; Moylan, S.; Maes, M. Role ofimmune-inflammatory and oxidative and nitrosative stresspathways in the etiology of depression: therapeutic implications. CNS Drugs, 2014, 28(1), 1-10. http://dx.doi.org/10.1007/s40263-013-0119-1
    • (2014) CNS Drugs , vol.28 , Issue.1 , pp. 1-10
    • Erson, G.1    Berk, M.2    Dean, O.3    Moylan, S.4    Maes, M.5
  • 7
    • 84892687196 scopus 로고    scopus 로고
    • Theintegrative management of treatment-resistant depression: Acomprehensive review and perspectives. Psychother
    • Carvalho, A.F.; Berk, M.; Hyphantis, T.N.; McIntyre, R.S. Theintegrative management of treatment-resistant depression: Acomprehensive review and perspectives. Psychother. Psychosom.,2014, 83(2), 70-88. http://dx.doi.org/10.1159/000357500
    • (2014) Psychosom. , vol.83 , Issue.2 , pp. 70-88
    • Carvalho, A.F.1    Berk, M.2    Hyphantis, T.N.3    McIntyre, R.S.4
  • 8
    • 80052482188 scopus 로고    scopus 로고
    • Cognitive impairmentin the remitted state of unipolar depressive disorder: A systematicreview
    • Hasselbalch, B.J.; Knorr, U.; Kessing, L.V. Cognitive impairmentin the remitted state of unipolar depressive disorder: a systematicreview. J. Affect. Disord., 2011, 134(1-3), 20-31. http://dx.doi.org/10.1016/j.jad.2010.11.011
    • (2011) J. Affect. Disord. , vol.134 , Issue.13 , pp. 20-31
    • Hasselbalch, B.J.1    Knorr, U.2    Kessing, L.V.3
  • 9
    • 79954604454 scopus 로고    scopus 로고
    • The new '5-HT' hypothesis of depression: Cell-mediated immuneactivation induces indoleamine 2,3-dioxygenase, which leads tolower plasma tryptophan and an increased synthesis of detrimentaltryptophan catabolites (TRYCATs), both of which contribute to theonset of depression
    • Maes, M.; Leonard, B.E.; Myint, A.M.; Kubera, M.; Verkerk, R. The new '5-HT' hypothesis of depression: cell-mediated immuneactivation induces indoleamine 2,3-dioxygenase, which leads tolower plasma tryptophan and an increased synthesis of detrimentaltryptophan catabolites (TRYCATs), both of which contribute to theonset of depression. Prog. Neuro-Pychopharmacol. Biol. Psychiatry,2011, 35(3), 702-721. http://dx.doi.org/10.1016/j.pnpbp.2010.12.017
    • (2011) Prog. Neuro-Pychopharmacol. Biol. Psychiatry , vol.35 , Issue.3 , pp. 702-721
    • Maes, M.1    Leonard, B.E.2    Myint, A.M.3    Kubera, M.4    Verkerk, R.5
  • 10
    • 84889256377 scopus 로고    scopus 로고
    • Impact of inflammation on neurotransmitter changesin major depression: An insight into the action of antidepressants
    • Leonard, B.E. Impact of inflammation on neurotransmitter changesin major depression: an insight into the action of antidepressants. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2014, 48, 261-267. http://dx.doi.org/10.1016/j.pnpbp.2013.10.018
    • (2014) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.48 , pp. 261-267
    • Leonard, B.E.1
  • 11
    • 84857361203 scopus 로고    scopus 로고
    • Increased autoimmune activity against 5-HT: A key component ofdepression that is associated with inflammation and activation ofcell-mediated immunity, and with severity and staging ofdepression
    • Maes, M.; Ringel, K.; Kubera, M.; Berk, M.; Rybakowski, J. Increased autoimmune activity against 5-HT: a key component ofdepression that is associated with inflammation and activation ofcell-mediated immunity, and with severity and staging ofdepression. J. Affect. Disord., 2012, 136(3), 386-392. http://dx.doi.org/10.1016/j.jad.2011.11.016
    • (2012) J. Affect. Disord. , vol.136 , Issue.3 , pp. 386-392
    • Maes, M.1    Ringel, K.2    Kubera, M.3    Berk, M.4    Rybakowski, J.5
  • 12
    • 84867582069 scopus 로고    scopus 로고
    • Effect of celecoxib add-on treatment onsymptoms and serum IL-6 concentrations in patients with majordepressive disorder: Randomized double-blind placebo-controlledstudy
    • Abbasi, S.H.; Hosseini, F.; Modabbernia, A.; Ashrafi, M.; Akhondzadeh, S. Effect of celecoxib add-on treatment onsymptoms and serum IL-6 concentrations in patients with majordepressive disorder: randomized double-blind placebo-controlledstudy. J. Affect. Disord., 2012, 141(2-3), 308-314. http://dx.doi.org/10.1016/j.jad.2012.03.033
    • (2012) J. Affect. Disord. , vol.141 , Issue.23 , pp. 308-314
    • Abbasi, S.H.1    Hosseini, F.2    Modabbernia, A.3    Ashrafi, M.4    Akhondzadeh, S.5
  • 13
    • 68049129642 scopus 로고    scopus 로고
    • Oxidative stress parameters after combined fluoxetine andacetylsalicylic acid therapy in depressive patients
    • Galecki, P.; Szemraj, J.; Bienkiewicz, M.; Zboralski, K.; Galecka, E. Oxidative stress parameters after combined fluoxetine andacetylsalicylic acid therapy in depressive patients. Hum. Psychopharmacol.,2009, 24(4), 277-286. http://dx.doi.org/10.1002/hup.1014
    • (2009) Hum. Psychopharmacol. , vol.24 , Issue.4 , pp. 277-286
    • Galecki, P.1    Szemraj, J.2    Bienkiewicz, M.3    Zboralski, K.4    Galecka, E.5
  • 14
    • 84865583011 scopus 로고    scopus 로고
    • Novel therapeutictargets in depression: Minocycline as a candidate treatment
    • Soczynska, J.K.; Mansur, R.B.; Brietzke, E. Novel therapeutictargets in depression: minocycline as a candidate treatment. Behav.Brain Res., 2012, 235(2), 302-317. http://dx.doi.org/10.1016/j.bbr.2012.07.026
    • (2012) Behav.Brain Res. , vol.235 , Issue.2 , pp. 302-317
    • Soczynska, J.K.1    Mansur, R.B.2    Brietzke, E.3
  • 15
    • 84859571611 scopus 로고    scopus 로고
    • Minocycline as adjunctivetherapy for patients with unipolar psychotic depression: An openlabelstudy
    • Miyaoka, T.; Wake, R.; Furuya, M. Minocycline as adjunctivetherapy for patients with unipolar psychotic depression: an openlabelstudy. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2012,37(2), 222-226. http://dx.doi.org/10.1016/j.pnpbp.2012.02.002
    • (2012) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.37 , Issue.2 , pp. 222-226
    • Miyaoka, T.1    Wake, R.2    Furuya, M.3
  • 16
    • 34548463097 scopus 로고    scopus 로고
    • Disabilityin major depression related to self-rated and objectively-measuredcognitive deficits: A preliminary study
    • Naismith, S.L.; Longley, W.A.; Scott, E.M.; Hickie, I.B. Disabilityin major depression related to self-rated and objectively-measuredcognitive deficits: a preliminary study. BMC Psychiatry, 2007, 7,32. http://dx.doi.org/10.1186/1471-244X-7-32
    • (2007) BMC Psychiatry , vol.7 , pp. 32
    • Naismith, S.L.1    Longley, W.A.2    Scott, E.M.3    Hickie, I.B.4
  • 17
    • 77957374545 scopus 로고    scopus 로고
    • Inflammation-induced anhedonia:Endotoxin reduces ventral striatum responses to reward
    • Eisenberger, N.I.; Berkman, E.T.; Inagaki, T.K.; Rameson, L.T.; Mashal, N.M.; Irwin, M.R. Inflammation-induced anhedonia:endotoxin reduces ventral striatum responses to reward. Biol.Psychiatry, 2010, 68(8), 748-754. http://dx.doi.org/10.1016/j.biopsych.2010.06.010
    • (2010) Biol.Psychiatry , vol.68 , Issue.8 , pp. 748-754
    • Eisenberger, N.I.1    Berkman, E.T.2    Inagaki, T.K.3    Rameson, L.T.4    Mashal, N.M.5    Irwin, M.R.6
  • 18
    • 78649657571 scopus 로고    scopus 로고
    • Dorsal vs ventral hippocampal neurogenesis:Implications for cognition and mood
    • Kheirbek, M.A.; Hen, R. Dorsal vs ventral hippocampal neurogenesis:implications for cognition and mood. Neuropsychopharmacology,2011, 36(1), 373-374. http://dx.doi.org/10.1038/npp.2010.148
    • (2011) Neuropsychopharmacology , vol.36 , Issue.1 , pp. 373-374
    • Kheirbek, M.A.1    Hen, R.2
  • 19
    • 77949281906 scopus 로고    scopus 로고
    • Enhancing outcomes from major depression: Usingantidepressant combination therapies with multifunctionalpharmacologic mechanisms from the initiation of treatment
    • Stahl, S.M. Enhancing outcomes from major depression: usingantidepressant combination therapies with multifunctionalpharmacologic mechanisms from the initiation of treatment. CNSSpectr., 2010, 15 (2), 79-94.
    • (2010) Cnsspectr. , vol.15 , Issue.2 , pp. 79-94
    • Stahl, S.M.1
  • 20
    • 84889097583 scopus 로고    scopus 로고
    • Is there an association between peripheralimmune markers and structural/functional neuroimaging findings?
    • Frodl, T.; Amico, F. Is there an association between peripheralimmune markers and structural/functional neuroimaging findings? Prog. Neuropsychopharmacol. Biol. Psychiatry, 2014, 48, 295-303. http://dx.doi.org/10.1016/j.pnpbp.2012.12.013
    • (2014) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.48 , pp. 295-303
    • Frodl, T.1    Amico, F.2
  • 21
    • 78049266766 scopus 로고    scopus 로고
    • The roles of TNF in braindysfunction and disease. Pharmacol
    • Clark, I.A.; Alleva, L.M.; Vissel, B. The roles of TNF in braindysfunction and disease. Pharmacol. Ther., 2010, 128 (3), 519-48. http://dx.doi.org/10.1016/j.pharmthera.2010.08.007
    • (2010) Ther. , vol.128 , Issue.3 , pp. 519-548
    • Clark, I.A.1    Alleva, L.M.2    Vissel, B.3
  • 22
    • 80054107097 scopus 로고    scopus 로고
    • Depressive-like behavior induced by tumornecrosis factor-alpha in mice
    • Kaster, M.P.; Gadotti, V.M.; Calixto, J.B.; Santos, A.R.; Rodrigues, A.L. Depressive-like behavior induced by tumornecrosis factor-alpha in mice. Neuropharmacology, 2012, 62 (1),419-426. http://dx.doi.org/10.1016/j.neuropharm.2011.08.018
    • (2012) Neuropharmacology , vol.62 , Issue.1 , pp. 419-426
    • Kaster, M.P.1    Gadotti, V.M.2    Calixto, J.B.3    Santos, A.R.4    Rodrigues, A.L.5
  • 23
    • 84874938625 scopus 로고    scopus 로고
    • Depressive-like behaviour induced by anintracerebroventricular injection of streptozotocin in mice: Theprotective effect of fluoxetine, antitumour necrosis factor-alpha andthalidomide therapies
    • Souza, L.C.; Filho, C.B.; Fabbro, L.D.; de Gomes, M.G.; Goes, A.T.; Jesse, C.R. Depressive-like behaviour induced by anintracerebroventricular injection of streptozotocin in mice: Theprotective effect of fluoxetine, antitumour necrosis factor-alpha andthalidomide therapies. Behav. Pharmacol., 2013, 24(2), 79-86. http://dx.doi.org/10.1097/FBP.0b013e32835efc2f
    • (2013) Behav. Pharmacol. , vol.24 , Issue.2 , pp. 79-86
    • Souza, L.C.1    Filho, C.B.2    Fabbro, L.D.3    De Gomes, M.G.4    Goes, A.T.5    Jesse, C.R.6
  • 24
    • 84856078575 scopus 로고    scopus 로고
    • TNF-alpha protein synthesisinhibitor restores neuronal function and reverses cognitive deficitsinduced by chronic neuroinflammation
    • Belarbi, K.; Jopson, T.; Tweedie, D. TNF-alpha protein synthesisinhibitor restores neuronal function and reverses cognitive deficitsinduced by chronic neuroinflammation. J. Neuroinflamm., 2012, 9,23. http://dx.doi.org/10.1186/1742-2094-9-23
    • (2012) J. Neuroinflamm. , vol.9 , pp. 23
    • Belarbi, K.1    Jopson, T.2    Tweedie, D.3
  • 25
    • 38749102020 scopus 로고    scopus 로고
    • Pro-inflammatory cytokinesand treatment response to escitalopram in major depressivedisorder
    • Eller, T.; Vasar, V.; Shlik, J.; Maron, E. Pro-inflammatory cytokinesand treatment response to escitalopram in major depressivedisorder. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2008,32(2), 445-450. http://dx.doi.org/10.1016/j.pnpbp.2007.09.015
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , Issue.2 , pp. 445-450
    • Eller, T.1    Vasar, V.2    Shlik, J.3    Maron, E.4
  • 26
    • 84871986003 scopus 로고    scopus 로고
    • A randomizedcontrolled trial of the tumor necrosis factor antagonist infliximabfor treatment-resistant depression: The role of baselineinflammatory biomarkers
    • Raison, C.L.; Rutherford, R.E.; Woolwine, B.J. A randomizedcontrolled trial of the tumor necrosis factor antagonist infliximabfor treatment-resistant depression: the role of baselineinflammatory biomarkers. JAMA Psychiatry, 2013, 70(1), 31-41. http://dx.doi.org/10.1001/2013.jamapsychiatry.4
    • (2013) JAMA Psychiatry , vol.70 , Issue.1 , pp. 31-41
    • Raison, C.L.1    Rutherford, R.E.2    Woolwine, B.J.3
  • 27
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: Acomprehensive review
    • Tracey, D.; Klareskog, L.; Sasso, E.H.; Salfeld, J.G.; Tak, P.P. Tumor necrosis factor antagonist mechanisms of action: acomprehensive review. Pharmacol. Ther., 2008, 117(2), 244-279. http://dx.doi.org/10.1016/j.pharmthera.2007.10.001
    • (2008) Pharmacol. Ther. , vol.117 , Issue.2 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3    Salfeld, J.G.4    Tak, P.P.5
  • 28
    • 37849052961 scopus 로고    scopus 로고
    • TNFalpha blockade in humandiseases: Mechanisms and future directions
    • Wong, M.; Ziring, D.; Korin, Y. TNFalpha blockade in humandiseases: mechanisms and future directions. Clin. Immunol., 2008,126(2), 121-136. http://dx.doi.org/10.1016/j.clim.2007.08.013
    • (2008) Clin. Immunol. , vol.126 , Issue.2 , pp. 121-136
    • Wong, M.1    Ziring, D.2    Korin, Y.3
  • 29
    • 84875736874 scopus 로고    scopus 로고
    • Microglial CD14activated by iNOS contributes to neuroinflammation in cerebralischemia
    • Zhou, M.; Wang, C.M.; Yang, W.L.; Wang, P. Microglial CD14activated by iNOS contributes to neuroinflammation in cerebralischemia. Brain Res., 2013, 1506, 105-14. http://dx.doi.org/10.1016/j.brainres.2013.02.010
    • (2013) Brain Res. , vol.1506 , pp. 105-114
    • Zhou, M.1    Wang, C.M.2    Yang, W.L.3    Wang, P.4
  • 30
    • 0037218371 scopus 로고    scopus 로고
    • Critical paracrine interactionsbetween TNF-alpha and IL-10 regulate lipopolysaccharidestimulatedhuman choriodecidual cytokine and prostaglandin E2production
    • Sato, T.A.; Keelan, J.A.; Mitchell, M.D. Critical paracrine interactionsbetween TNF-alpha and IL-10 regulate lipopolysaccharidestimulatedhuman choriodecidual cytokine and prostaglandin E2production. J. Immunol., 2003, 170(1), 158-66. http://dx.doi.org/10.4049/jimmunol.170.1.158
    • (2003) J. Immunol. , vol.170 , Issue.1 , pp. 158-166
    • Sato, T.A.1    Keelan, J.A.2    Mitchell, M.D.3
  • 31
    • 17044383352 scopus 로고    scopus 로고
    • TNF pathophysiology in murine models of chronicinflammation and autoimmunity
    • Kollias, G. TNF pathophysiology in murine models of chronicinflammation and autoimmunity. Semin. Arthritis Rheum., 2005, 34(Suppl1), 3-6. http://dx.doi.org/10.1016/j.semarthrit.2005.01.002
    • (2005) Semin. Arthritis Rheum. , vol.34 , pp. 3-6
    • Kollias, G.1
  • 32
    • 0141832116 scopus 로고    scopus 로고
    • Lymphotoxin/light, lymphoidmicroenvironments and autoimmune disease
    • Gommerman, J.L.; Browning, J.L. Lymphotoxin/light, lymphoidmicroenvironments and autoimmune disease. Nat. Rev. Immunol.,2003, 3(8), 642-655. http://dx.doi.org/10.1038/nri1151
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.8 , pp. 642-655
    • Gommerman, J.L.1    Browning, J.L.2
  • 33
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory &neurodegenerative (I&ND) hypothesis of depression: Leads forfuture research and new drug developments in depression
    • Maes, M.; Yirmyia, R.; Noraberg, J. The inflammatory & neurodegenerative (I& ND) hypothesis of depression: leads forfuture research and new drug developments in depression. Metab.Brain Dis., 2009, 24(1), 27-53. http://dx.doi.org/10.1007/s11011-008-9118-1
    • (2009) Metab.Brain Dis. , vol.24 , Issue.1 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3
  • 34
    • 55049114476 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha modulates survival, proliferation,and neuronal differentiation in neonatal subventricular zone cellcultures
    • Bernardino, L.; Agasse, F.; Silva, B.; Ferreira, R.; Grade, S.; Malva, J.O. Tumor necrosis factor-alpha modulates survival, proliferation,and neuronal differentiation in neonatal subventricular zone cellcultures. Stem Cells, 2008, 26(9), 2361-2371. http://dx.doi.org/10.1634/stemcells.2007-0914
    • (2008) Stem Cells , vol.26 , Issue.9 , pp. 2361-2371
    • Bernardino, L.1    Agasse, F.2    Silva, B.3    Ferreira, R.4    Grade, S.5    Malva, J.O.6
  • 35
    • 33847759064 scopus 로고    scopus 로고
    • Systemic LPS causes chronicneuroinflammation and progressive neurodegeneration
    • Qin, L.; Wu, X.; Block, M.L. Systemic LPS causes chronicneuroinflammation and progressive neurodegeneration. Glia, 2007,55(5), 453-462. http://dx.doi.org/10.1002/glia.20467
    • (2007) Glia , vol.55 , Issue.5 , pp. 453-462
    • Qin, L.1    Wu, X.2    Block, M.L.3
  • 36
    • 55949104665 scopus 로고    scopus 로고
    • TNF signaling inhibition in the CNS:Implications for normal brain function and neurodegenerativedisease
    • McCoy, M.K.; Tansey, M.G. TNF signaling inhibition in the CNS:implications for normal brain function and neurodegenerativedisease. J. Neuroinflamm., 2008, 5, 45. http://dx.doi.org/10.1186/1742-2094-5-45
    • (2008) J. Neuroinflamm. , vol.5 , pp. 45
    • McCoy, M.K.1    Tansey, M.G.2
  • 37
    • 33644791099 scopus 로고    scopus 로고
    • TNF-alpha-secretingmonocytes are recruited into the brain of cholestatic mice
    • Kerfoot, S.M.; D'Mello, C.; Nguyen, H. TNF-alpha-secretingmonocytes are recruited into the brain of cholestatic mice. Hepatology, 2006, 43(1), 154-162. http://dx.doi.org/10.1002/hep.21003
    • (2006) Hepatology , vol.43 , Issue.1 , pp. 154-162
    • Kerfoot, S.M.1    D'mello, C.2    Nguyen, H.3
  • 39
    • 34547794475 scopus 로고    scopus 로고
    • The immune-mediated alteration ofserotonin and glutamate: Towards an integrated view of depression
    • Muller, N.; Schwarz, M.J. The immune-mediated alteration ofserotonin and glutamate: towards an integrated view of depression. Mol. Psychiatry, 2007, 12 (11), 988-1000. http://dx.doi.org/10.1038/sj.mp.4002006
    • (2007) Mol. Psychiatry , vol.12 , Issue.11 , pp. 988-1000
    • Muller, N.1    Schwarz, M.J.2
  • 40
    • 84860443755 scopus 로고    scopus 로고
    • Putative functional role foroligodendrocytes in mood regulation. Transl
    • Edgar, N.; Sibille, E. A putative functional role foroligodendrocytes in mood regulation. Transl. Psychiatry, 2012, 2,e109. http://dx.doi.org/10.1038/tp.2012.34
    • (2012) Psychiatry , vol.2
    • Edgar, N.1    Sibille, E.A.2
  • 41
    • 82955171270 scopus 로고    scopus 로고
    • Immunoexcitotoxicity as a centralmechanism in chronic traumatic encephalopathy-A unifying hypothesis
    • Blaylock, R.L.; Maroon, J. Immunoexcitotoxicity as a centralmechanism in chronic traumatic encephalopathy-A unifying hypothesis. Surg. Neurol. Int., 2011, 2, 107. http://dx.doi.org/10.4103/2152-7806.83391
    • (2011) Surg. Neurol. Int. , vol.2 , pp. 107
    • Blaylock, R.L.1    Maroon, J.2
  • 42
    • 16244376446 scopus 로고    scopus 로고
    • Differentialregulation of AMPA receptor and GABA receptor trafficking bytumor necrosis factor-alpha
    • Stellwagen, D.; Beattie, E.C.; Seo, J.Y.; Malenka, R.C. Differentialregulation of AMPA receptor and GABA receptor trafficking bytumor necrosis factor-alpha. J. Neurosci., 2005, 25 (12), 3219-3228. http://dx.doi.org/10.1523/JNEUROSCI.4486-04.2005
    • (2005) J. Neurosci. , vol.25 , Issue.12 , pp. 3219-3228
    • Stellwagen, D.1    Beattie, E.C.2    Seo, J.Y.3    Malenka, R.C.4
  • 43
    • 78651448663 scopus 로고    scopus 로고
    • Dopaminergic neuronal injury in theadult rat brain following neonatal exposure to lipopolysaccharideand the silent neurotoxicity
    • Fan, L.W.; Tien, L.T.; Zheng, B. Dopaminergic neuronal injury in theadult rat brain following neonatal exposure to lipopolysaccharideand the silent neurotoxicity. Brain Behav. Immun., 2011, 25(2),286-297. http://dx.doi.org/10.1016/j.bbi.2010.09.020
    • (2011) Brain Behav. Immun. , vol.25 , Issue.2 , pp. 286-297
    • Fan, L.W.1    Tien, L.T.2    Zheng, B.3
  • 44
    • 0037155582 scopus 로고    scopus 로고
    • Control of synapticstrength by glial TNFalpha
    • Beattie, E.C.; Stellwagen, D.; Morishita, W. Control of synapticstrength by glial TNFalpha. Science, 2002, 295 (5563), 2282-2285. http://dx.doi.org/10.1126/science.1067859
    • (2002) Science , vol.295 , Issue.5563 , pp. 2282-2285
    • Beattie, E.C.1    Stellwagen, D.2    Morishita, W.3
  • 45
    • 1242339720 scopus 로고    scopus 로고
    • Dissection of tumornecrosisfactor-alpha inhibition of long-term potentiation (LTP)reveals a p38 mitogen-activated protein kinase-dependent mechanismwhich maps to early-but not late-phase LTP
    • Butler, M.P.; O'Connor, J.J.; Moynagh, P.N. Dissection of tumornecrosisfactor-alpha inhibition of long-term potentiation (LTP)reveals a p38 mitogen-activated protein kinase-dependent mechanismwhich maps to early-but not late-phase LTP. Neuroscience, 2004,124 (2), 319-326. http://dx.doi.org/10.1016/j.neuroscience.2003.11.040
    • (2004) Neuroscience , vol.124 , Issue.2 , pp. 319-326
    • Butler, M.P.1    O'connor, J.J.2    Moynagh, P.N.3
  • 46
    • 74749106708 scopus 로고    scopus 로고
    • Neonatalintrahippocampal immune challenge alters dopamine modulation ofprefrontal cortical interneurons in adult rats
    • Feleder, C.; Tseng, K.Y.; Calhoon, G.G.; O'Donnell, P. Neonatalintrahippocampal immune challenge alters dopamine modulation ofprefrontal cortical interneurons in adult rats. Biol. Psychiatry, 2010,67(4), 386-392. http://dx.doi.org/10.1016/j.biopsych.2009.09.028
    • (2010) Biol. Psychiatry , vol.67 , Issue.4 , pp. 386-392
    • Feleder, C.1    Tseng, K.Y.2    Calhoon, G.G.3    O'donnell, P.4
  • 47
    • 84892449583 scopus 로고    scopus 로고
    • Tumor necrosis factor-alphaduring neonatal brain development affects anxiety- and depressionrelatedbehaviors in adult male and female mice
    • Babri, S.; Doosti, M.H.; Salari, A.A. Tumor necrosis factor-alphaduring neonatal brain development affects anxiety- and depressionrelatedbehaviors in adult male and female mice. Behav. Brain Res.,2014, 261, 305-314. http://dx.doi.org/10.1016/j.bbr.2013.12.037
    • (2014) Behav. Brain Res. , vol.261 , pp. 305-314
    • Babri, S.1    Doosti, M.H.2    Salari, A.A.3
  • 48
    • 0036121098 scopus 로고    scopus 로고
    • TNF receptor subtype signalling: Differences andcellular consequences
    • MacEwan, D.J. TNF receptor subtype signalling: differences andcellular consequences. Cell. Signal., 2002, 14(6), 477-492. http://dx.doi.org/10.1016/S0898-6568(01)00262-5
    • (2002) Cell. Signal. , vol.14 , Issue.6 , pp. 477-492
    • Macewan, D.J.1
  • 49
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia, Z.; Dickens, M.; Raingeaud, J.; Davis, R.J.; Greenberg, M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science, 1995, 270(5240), 1326-1331. http://dx.doi.org/10.1126/science.270.5240.1326
    • (1995) Science , vol.270 , Issue.5240 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 50
    • 52949147794 scopus 로고    scopus 로고
    • Roles of continuousneurogenesis in the structural and functional integrity of the adultforebrain
    • Imayoshi, I.; Sakamoto, M.; Ohtsuka, T. Roles of continuousneurogenesis in the structural and functional integrity of the adultforebrain. Nat. Neurosci., 2008, 11(10), 1153-1161. http://dx.doi.org/10.1038/nn.2185
    • (2008) Nat. Neurosci. , vol.11 , Issue.10 , pp. 1153-1161
    • Imayoshi, I.1    Sakamoto, M.2    Ohtsuka, T.3
  • 51
    • 3543046113 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-mediated neuroprotection againstglutamate-induced excitotoxicity is enhanced by N-methyl-Daspartatereceptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa Bpathway
    • Marchetti, L.; Klein, M.; Schlett, K.; Pfizenmaier, K.; Eisel, U.L. Tumor necrosis factor (TNF)-mediated neuroprotection againstglutamate-induced excitotoxicity is enhanced by N-methyl-Daspartatereceptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa Bpathway. J. Biol. Chem., 2004, 279 (31), 32869-32881. http://dx.doi.org/10.1074/jbc.M311766200
    • (2004) J. Biol. Chem. , vol.279 , Issue.31 , pp. 32869-32881
    • Marchetti, L.1    Klein, M.2    Schlett, K.3    Pfizenmaier, K.4    Eisel, U.L.5
  • 52
    • 84861556594 scopus 로고    scopus 로고
    • Inhibition of solubletumor necrosis factor ameliorates synaptic alterations and Ca2+dysregulation in aged rats
    • Sama, D.M.; Mohmmad, A. H.; Furman, J.L. Inhibition of solubletumor necrosis factor ameliorates synaptic alterations and Ca2+dysregulation in aged rats. PloS One, 2012, 7(5), e38170. http://dx.doi.org/10.1371/journal.pone.0038170
    • (2012) Plos One , vol.7 , Issue.5 , pp. 38170
    • Sama, D.M.1    Mohmmad, A.H.2    Furman, J.L.3
  • 53
    • 19944382538 scopus 로고    scopus 로고
    • Cytokines asmediators of depression: What can we learn from animal studies?
    • Dunn, A.J.; Swiergiel, A.H.; de Beaurepaire, R. Cytokines asmediators of depression: what can we learn from animal studies?Neurosci. Biobehav. Rev., 2005, 29(45), 891-909. http://dx.doi.org/10.1016/j.neubiorev.2005.03.023
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , Issue.45 , pp. 891-909
    • Dunn, A.J.1    Swiergiel, A.H.2    De Beaurepaire, R.3
  • 54
    • 79960884919 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory cytokinesexpression in rat's brain and spleen exposed to chronic mild stress:Involvement in depression
    • You, Z.; Luo, C.; Zhang, W. Pro- and anti-inflammatory cytokinesexpression in rat's brain and spleen exposed to chronic mild stress:involvement in depression. Behav. Brain Res., 2011, 225(1), 135-141. http://dx.doi.org/10.1016/j.bbr.2011.07.006
    • (2011) Behav. Brain Res. , vol.225 , Issue.1 , pp. 135-141
    • You, Z.1    Luo, C.2    Zhang, W.3
  • 55
    • 84881117875 scopus 로고    scopus 로고
    • Systemic tumornecrosis factor-alpha decreases brain stimulation reward andincreases metabolites of serotonin and dopamine in the nucleusaccumbens of mice
    • van Heesch, F.; Prins, J.; Korte-Bouws, G.A. Systemic tumornecrosis factor-alpha decreases brain stimulation reward andincreases metabolites of serotonin and dopamine in the nucleusaccumbens of mice. Behav. Brain Res., 2013, 253, 191-195. http://dx.doi.org/10.1016/j.bbr.2013.07.038
    • (2013) Behav. Brain Res. , vol.253 , pp. 191-195
    • Van Heesch, F.1    Prins, J.2    Korte-Bouws, G.A.3
  • 56
    • 33748808678 scopus 로고    scopus 로고
    • The proinflammatorycytokines interleukin-1beta and tumor necrosis factor-alphaactivate serotonin transporters
    • Zhu, C.B.; Blakely, R.D.; Hewlett, W.A. The proinflammatorycytokines interleukin-1beta and tumor necrosis factor-alphaactivate serotonin transporters. Neuropsychopharmacology, 2006,31(10), 2121-2131. http://dx.doi.org/10.1038/sj.npp.1301029
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2121-2131
    • Zhu, C.B.1    Blakely, R.D.2    Hewlett, W.A.3
  • 57
    • 33646101010 scopus 로고    scopus 로고
    • TNFalphasignaling in depression and anxiety: Behavioral consequences ofindividual receptor targeting
    • Simen, B.B.; Duman, C.H.; Simen, A.A.; Duman, R.S. TNFalphasignaling in depression and anxiety: behavioral consequences ofindividual receptor targeting. Biol. Psychiatry, 2006, 59(9), 775-785. http://dx.doi.org/10.1016/j.biopsych.2005.10.013
    • (2006) Biol. Psychiatry , vol.59 , Issue.9 , pp. 775-785
    • Simen, B.B.1    Duman, C.H.2    Simen, A.A.3    Duman, R.S.4
  • 58
    • 0034333060 scopus 로고    scopus 로고
    • Neurobehavioral alterations inmice with a targeted deletion of the tumor necrosis factor-alpha gene:Implications for emotional behavior
    • Yamada, K.; Iida, R.; Miyamoto, Y. Neurobehavioral alterations inmice with a targeted deletion of the tumor necrosis factor-alpha gene:implications for emotional behavior. J. Neuroimmunol., 2000,111(12), 131-138. http://dx.doi.org/10.1016/S0165-5728(00)00375-1
    • (2000) J. Neuroimmunol. , vol.111 , Issue.12 , pp. 131-138
    • Yamada, K.1    Iida, R.2    Miyamoto, Y.3
  • 59
    • 59249085094 scopus 로고    scopus 로고
    • Evidence for a cytokine model ofcognitive function
    • McAfoose, J.; Baune, B.T. Evidence for a cytokine model ofcognitive function. Neurosci. Biobehav. Rev., 2009, 33(3), 355-366. http://dx.doi.org/10.1016/j.neubiorev.2008.10.005
    • (2009) Neurosci. Biobehav. Rev. , vol.33 , Issue.3 , pp. 355-366
    • McAfoose, J.1    Baune, B.T.2
  • 60
    • 50549094089 scopus 로고    scopus 로고
    • Interpreting crosstalk between TNF-alphaand NGF: Potential implications for disease
    • Takei, Y.; Laskey, R. Interpreting crosstalk between TNF-alphaand NGF: potential implications for disease. Trends Mol. Med.,2008, 14(9), 381-388. http://dx.doi.org/10.1016/j.molmed.2008.07.002
    • (2008) Trends Mol. Med. , vol.14 , Issue.9 , pp. 381-388
    • Takei, Y.1    Laskey, R.2
  • 61
    • 0346992335 scopus 로고    scopus 로고
    • Involvementof tumor necrosis factor alpha in hippocampal development andfunction
    • Golan, H.; Levav, T.; Mendelsohn, A.; Huleihel, M. Involvementof tumor necrosis factor alpha in hippocampal development andfunction. Cereb. Cortex, 2004, 14(1), 97-105. http://dx.doi.org/10.1093/cercor/bhg108
    • (2004) Cereb. Cortex , vol.14 , Issue.1 , pp. 97-105
    • Golan, H.1    Levav, T.2    Mendelsohn, A.3    Huleihel, M.4
  • 63
    • 84873531039 scopus 로고    scopus 로고
    • Long-termtreatment of thalidomide ameliorates amyloid-like pathologythrough inhibition of beta-secretase in a mouse model of Alzheimer'sdisease
    • He, P.; Cheng, X.; Staufenbiel, M.; Li, R.; Shen, Y. Long-termtreatment of thalidomide ameliorates amyloid-like pathologythrough inhibition of beta-secretase in a mouse model of Alzheimer'sdisease. PloS One, 2013, 8(2), e55091. http://dx.doi.org/10.1371/journal.pone.0055091
    • (2013) Plos One , vol.8 , Issue.2
    • He, P.1    Cheng, X.2    Staufenbiel, M.3    Li, R.4    Shen, Y.5
  • 64
    • 79954621673 scopus 로고    scopus 로고
    • Inanimal models, psychosocial stress-induced (Neuro) inflammation,apoptosis and reduced neurogenesis are associated to the onset ofdepression
    • Kubera, M.; Obuchowicz, E.; Goehler, L.; Brzeszcz, J.; Maes, M. Inanimal models, psychosocial stress-induced (neuro) inflammation,apoptosis and reduced neurogenesis are associated to the onset ofdepression. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2011,35(3), 744-759. http://dx.doi.org/10.1016/j.pnpbp.2010.08.026
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , Issue.3 , pp. 744-759
    • Kubera, M.1    Obuchowicz, E.2    Goehler, L.3    Brzeszcz, J.4    Maes, M.5
  • 65
    • 33646548627 scopus 로고    scopus 로고
    • A new chapter opens in anti-inflammatory treatments:The antidepressant bupropion lowers production of tumor necrosisfactor-alpha and interferon-gamma in mice
    • Brustolim, D.; Ribeiro-dos-Santos, R.; Kast, R.E.; Altschuler, E. L.; Soares, M.B. A new chapter opens in anti-inflammatory treatments:the antidepressant bupropion lowers production of tumor necrosisfactor-alpha and interferon-gamma in mice. Int. Immunopharmacol.,2006, 6(6), 903-907. http://dx.doi.org/10.1016/j.intimp.2005.12.007
    • (2006) Int. Immunopharmacol. , vol.6 , Issue.6 , pp. 903-907
    • Brustolim, D.1    Ribeiro-Dos-santos, R.2    Kast, R.E.3    Altschuler, E.L.4    Soares, M.B.5
  • 66
    • 0028217712 scopus 로고
    • Catalase, superoxidedismutase and glutathione peroxidase activity in neutrophils ofsham-operated and olfactory-bulbectomised rats following chronictreatment with desipramine and lithium chloride
    • Song, C.; Killeen, A.A.; Leonard, B.E. Catalase, superoxidedismutase and glutathione peroxidase activity in neutrophils ofsham-operated and olfactory-bulbectomised rats following chronictreatment with desipramine and lithium chloride. Neuropsychobiology,1994, 30 (1), 24-8. http://dx.doi.org/10.1159/000119131
    • (1994) Neuropsychobiology , vol.30 , Issue.1 , pp. 24-28
    • Song, C.1    Killeen, A.A.2    Leonard, B.E.3
  • 67
    • 32544444248 scopus 로고    scopus 로고
    • The effectsof chronic fluoxetine treatment on chronic mild stress-inducedcardiovascular changes and anhedonia
    • Grippo, A.J.; Beltz, T.G.; Weiss, R.M.; Johnson, A.K. The effectsof chronic fluoxetine treatment on chronic mild stress-inducedcardiovascular changes and anhedonia. Biol. Psychiatry, 2006,59(4), 309-316. http://dx.doi.org/10.1016/j.biopsych.2005.07.010
    • (2006) Biol. Psychiatry , vol.59 , Issue.4 , pp. 309-316
    • Grippo, A.J.1    Beltz, T.G.2    Weiss, R.M.3    Johnson, A.K.4
  • 68
    • 84872534794 scopus 로고    scopus 로고
    • Effects ofantidepressants on alternations in serum cytokines and depressivelikebehavior in mice after lipopolysaccharide administration.Pharmacol
    • Ohgi, Y.; Futamura, T.; Kikuchi, T.; Hashimoto, K. Effects ofantidepressants on alternations in serum cytokines and depressivelikebehavior in mice after lipopolysaccharide administration.Pharmacol. Biochem. Behav., 2013, 103(4), 853-859. http://dx.doi.org/10.1016/j.pbb.2012.12.003
    • (2013) Biochem. Behav. , vol.103 , Issue.4 , pp. 853-859
    • Ohgi, Y.1    Futamura, T.2    Kikuchi, T.3    Hashimoto, K.4
  • 69
    • 84857192442 scopus 로고    scopus 로고
    • A comparative examination of the antiinflammatoryeffects of SSRI and SNRI antidepressants on LPSstimulated microglia
    • Tynan, R.J.; Weidenhofer, J.; Hinwood, M.; Cairns, M.J.; Day, T.A.; Walker, F.R. A comparative examination of the antiinflammatoryeffects of SSRI and SNRI antidepressants on LPSstimulated microglia. Brain Behav. Immun., 2012, 26(3), 469-479. http://dx.doi.org/10.1016/j.bbi.2011.12.011
    • (2012) Brain Behav. Immun. , vol.26 , Issue.3 , pp. 469-479
    • Tynan, R.J.1    Weidenhofer, J.2    Hinwood, M.3    Cairns, M.J.4    Day, T.A.5    Walker, F.R.6
  • 70
    • 79959953811 scopus 로고    scopus 로고
    • Antiinflammatoryeffects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells
    • Liu, D.; Wang, Z.; Liu, S.; Wang, F.; Zhao, S.; Hao, A. Antiinflammatoryeffects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells. Neuropharmacology, 2011, 61(4), 592-599. http://dx.doi.org/10.1016/j.neuropharm.2011.04.033
    • (2011) Neuropharmacology , vol.61 , Issue.4 , pp. 592-599
    • Liu, D.1    Wang, Z.2    Liu, S.3    Wang, F.4    Zhao, S.5    Hao, A.6
  • 71
    • 84883011632 scopus 로고    scopus 로고
    • Fluoxetine and citalopram decrease microglial release of glutamateand D-serine to promote cortical neuronal viability followingischemic insult
    • Dhami, K.S.; Churchward, M.A.; Baker, G.B.; Todd, K.G. Fluoxetine and citalopram decrease microglial release of glutamateand D-serine to promote cortical neuronal viability followingischemic insult. Mol. Cell. Neurosci., 2013, 56, 365-374. http://dx.doi.org/10.1016/j.mcn.2013.07.006
    • (2013) Mol. Cell. Neurosci. , vol.56 , pp. 365-374
    • Dhami, K.S.1    Churchward, M.A.2    Baker, G.B.3    Todd, K.G.4
  • 72
    • 33746354022 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha inducesneurotoxicity via glutamate release from hemichannels of activatedmicroglia in an autocrine manner
    • Takeuchi, H.; Jin, S.; Wang, J. Tumor necrosis factor-alpha inducesneurotoxicity via glutamate release from hemichannels of activatedmicroglia in an autocrine manner. J. Biol. Chem., 2006, 281 (30),21362-8. http://dx.doi.org/10.1074/jbc.M600504200
    • (2006) J. Biol. Chem. , vol.281 , Issue.30 , pp. 21362-21368
    • Takeuchi, H.1    Jin, S.2    Wang, J.3
  • 73
    • 34249107980 scopus 로고    scopus 로고
    • Desipramine activated Bcl-2expression and inhibited lipopolysaccharide-induced apoptosis inhippocampus-derived adult neural stem cells
    • Huang, Y.Y.; Peng, C.H.; Yang, Y.P. Desipramine activated Bcl-2expression and inhibited lipopolysaccharide-induced apoptosis inhippocampus-derived adult neural stem cells. J. Pharmacol. Sci.,2007, 104(1), 61-72. http://dx.doi.org/10.1254/jphs.FP0061255
    • (2007) J. Pharmacol. Sci. , vol.104 , Issue.1 , pp. 61-72
    • Huang, Y.Y.1    Peng, C.H.2    Yang, Y.P.3
  • 74
    • 84857194922 scopus 로고    scopus 로고
    • Activation of serotonin receptors promotesmicroglial injury-induced motility but attenuates phagocyticactivity
    • Krabbe, G.; Matyash, V.; Pannasch, U.; Mamer, L.; Boddeke, H.W.; Kettenmann, H. Activation of serotonin receptors promotesmicroglial injury-induced motility but attenuates phagocyticactivity. Brain Behav. Immun., 2012, 26(3), 419-428. http://dx.doi.org/10.1016/j.bbi.2011.12.002
    • (2012) Brain Behav. Immun. , vol.26 , Issue.3 , pp. 419-428
    • Krabbe, G.1    Matyash, V.2    Pannasch, U.3    Mamer, L.4    Boddeke, H.W.5    Kettenmann, H.6
  • 75
    • 79959994418 scopus 로고    scopus 로고
    • Fluoxetineregulates the expression of neurotrophic/growth factors and glucosemetabolism in astrocytes
    • Allaman, I.; Fiumelli, H.; Magistretti, P.J.; Martin, J.L. Fluoxetineregulates the expression of neurotrophic/growth factors and glucosemetabolism in astrocytes. Psychopharmacology, 2011, 216(1), 75-84. http://dx.doi.org/10.1007/s00213-011-2190-y
    • (2011) Psychopharmacology , vol.216 , Issue.1 , pp. 75-84
    • Allaman, I.1    Fiumelli, H.2    Magistretti, P.J.3    Martin, J.L.4
  • 76
    • 84875235624 scopus 로고    scopus 로고
    • Antidepressants act directly on astrocytes:Evidences and functional consequences
    • Czeh, B.; Di Benedetto, B. Antidepressants act directly on astrocytes:evidences and functional consequences. Eur. Neuropsychopharmacol.,2013, 23 (3), 171-185. http://dx.doi.org/10.1016/j.euroneuro.2012.04.017
    • (2013) Eur. Neuropsychopharmacol. , vol.23 , Issue.3 , pp. 171-185
    • Czeh, B.1    Di Benedetto, B.2
  • 77
    • 84861427387 scopus 로고    scopus 로고
    • Microglia sculptpostnatal neural circuits in an activity and complement-dependent manner
    • Schafer, D.P.; Lehrman, E.K.; Kautzman, A.G. Microglia sculptpostnatal neural circuits in an activity and complement-dependent manner. Neuron, 2012, 74(4), 691-705. http://dx.doi.org/10.1016/j.neuron.2012.03.026
    • (2012) Neuron , vol.74 , Issue.4 , pp. 691-705
    • Schafer, D.P.1    Lehrman, E.K.2    Kautzman, A.G.3
  • 78
    • 70350218960 scopus 로고    scopus 로고
    • Critical review of human endotoxinadministration as an experimental paradigm of depression
    • Della, G. N.; Hannestad, J. A critical review of human endotoxinadministration as an experimental paradigm of depression. Neurosci. Biobehav. Rev., 2010, 34 (1), 130-43. http://dx.doi.org/10.1016/j.neubiorev.2009.07.014
    • (2010) Neurosci. Biobehav. Rev. , vol.34 , Issue.1 , pp. 130-143
    • Della, G.N.1    Hannestad, J.A.2
  • 79
    • 84872118489 scopus 로고    scopus 로고
    • Prenatalmaternal infection, neurodevelopment and adult schizophrenia: Asystematic review of population-based studies
    • Khandaker, G.M.; Zimbron, J.; Lewis, G.; Jones, P.B. Prenatalmaternal infection, neurodevelopment and adult schizophrenia: asystematic review of population-based studies. Psychol. Med., 2013,43(2), 239-257. http://dx.doi.org/10.1017/S0033291712000736
    • (2013) Psychol. Med. , vol.43 , Issue.2 , pp. 239-257
    • Khandaker, G.M.1    Zimbron, J.2    Lewis, G.3    Jones, P.B.4
  • 80
    • 29144498876 scopus 로고    scopus 로고
    • The vital link betweenchronic disease and depressive disorders
    • Chapman, D.P.; Perry, G.S.; Strine, T.W. The vital link betweenchronic disease and depressive disorders. Prev. Chronic Dis., 2005,2(1), A14.
    • (2005) Prev. Chronic Dis. , vol.2 , Issue.1 , pp. 14
    • Chapman, D.P.1    Perry, G.S.2    Strine, T.W.3
  • 81
    • 84900869730 scopus 로고    scopus 로고
    • Theprevalence and odds of depressive symptoms and clinical depressionin psoriasis patients: A systematic review and meta-analysis
    • Dowlatshahi, E.A.; Wakkee, M.; Arends, L.R.; Nijsten, T. Theprevalence and odds of depressive symptoms and clinical depressionin psoriasis patients: a systematic review and meta-analysis. J. Invest. Dermatol., 2014, 134(6), 1542-1551. http://dx.doi.org/10.1038/jid.2013.508
    • (2014) J. Invest. Dermatol. , vol.134 , Issue.6 , pp. 1542-1551
    • Dowlatshahi, E.A.1    Wakkee, M.2    Arends, L.R.3    Nijsten, T.4
  • 82
    • 77951220650 scopus 로고    scopus 로고
    • Psychiatric morbidity associated with some cytokines (IL-1beta,IL-12, IL-18 and TNF-alpha) among rheumatoid arthritis patients
    • El-Tantawy, A.M.; El-Sayed, A.E.; Kora, B.A.; Amin, R.T. Psychiatric morbidity associated with some cytokines (IL-1beta,IL-12, IL-18 and TNF-alpha) among rheumatoid arthritis patients. Egypt J. Immunol., 2008, 15(1), 1-11.
    • (2008) Egypt J. Immunol. , vol.15 , Issue.1 , pp. 1-11
    • El-Tantawy, A.M.1    El-Sayed, A.E.2    Kora, B.A.3    Amin, R.T.4
  • 83
    • 38049153269 scopus 로고    scopus 로고
    • Depressive symptoms in patients with chronic hepatitis C arecorrelated with elevated plasma levels of interleukin-1beta andtumor necrosis factor-alpha
    • Loftis, J.M.; Huckans, M.; Ruimy, S.; Hinrichs, D.J.; Hauser, P. Depressive symptoms in patients with chronic hepatitis C arecorrelated with elevated plasma levels of interleukin-1beta andtumor necrosis factor-alpha. Neurosci. Lett., 2008, 430(3), 264-268. http://dx.doi.org/10.1016/j.neulet.2007.11.001
    • (2008) Neurosci. Lett. , vol.430 , Issue.3 , pp. 264-268
    • Loftis, J.M.1    Huckans, M.2    Ruimy, S.3    Hinrichs, D.J.4    Hauser, P.5
  • 84
    • 79959597820 scopus 로고    scopus 로고
    • Persistent pro-inflammatory cytokines following theinitiation of pegylated IFN therapy in hepatitis C infection isassociated with treatment-induced depression
    • Krueger, C.; Hawkins, K.; Wong, S.; Enns, M.W.; Minuk, G.; Rempel, J.D. Persistent pro-inflammatory cytokines following theinitiation of pegylated IFN therapy in hepatitis C infection isassociated with treatment-induced depression. J. Viral Hepat.,2011, 18(7), e284-291. http://dx.doi.org/10.1111/j.1365-2893.2010.01408.x
    • (2011) J. Viral Hepat. , vol.18 , Issue.7 , pp. e284-e291
    • Krueger, C.1    Hawkins, K.2    Wong, S.3    Enns, M.W.4    Minuk, G.5    Rempel, J.D.6
  • 85
    • 62949083388 scopus 로고    scopus 로고
    • Increased soluble tumor necrosis factor-alphareceptors in patients with major depressive disorder
    • Grassi-Oliveira, R.; Brietzke, E.; Pezzi, J.C.; Lopes, R.P.; Teixeira, A. L.; Bauer, M. E. Increased soluble tumor necrosis factor-alphareceptors in patients with major depressive disorder. PsychiatryClin. Neurosci., 2009, 63(2), 202-208. http://dx.doi.org/10.1111/j.1440-1819.2008.01918.x
    • (2009) Psychiatryclin. Neurosci. , vol.63 , Issue.2 , pp. 202-208
    • Grassi-Oliveira, R.1    Brietzke, E.2    Pezzi, J.C.3    Lopes, R.P.4    Teixeira, A.L.5    Bauer, M.E.6
  • 86
    • 51249096556 scopus 로고    scopus 로고
    • Depression, comorbiditiesand the TNF-alpha system
    • Himmerich, H.; Fulda, S.; Linseisen, J. Depression, comorbiditiesand the TNF-alpha system. Eur. Psychiatry, 2008, 23(6), 421-429. http://dx.doi.org/10.1016/j.eurpsy.2008.03.013
    • (2008) Eur. Psychiatry , vol.23 , Issue.6 , pp. 421-429
    • Himmerich, H.1    Fulda, S.2    Linseisen, J.3
  • 87
    • 84876079221 scopus 로고    scopus 로고
    • Cytokinetargets in the brain: Impact on neurotransmitters and neurocircuits
    • Miller, A.H.; Haroon, E.; Raison, C.L.; Felger, J.C. Cytokinetargets in the brain: impact on neurotransmitters and neurocircuits. Depress. Anxiety, 2013, 30(4), 297-306. http://dx.doi.org/10.1002/da.22084
    • (2013) Depress. Anxiety , vol.30 , Issue.4 , pp. 297-306
    • Miller, A.H.1    Haroon, E.2    Raison, C.L.3    Felger, J.C.4
  • 88
    • 84862111527 scopus 로고    scopus 로고
    • Role ofcytokines in atypical depression
    • Yoon, H.K.; Kim, Y.K.; Lee, H.J.; Kwon, D.Y.; Kim, L. Role ofcytokines in atypical depression. Nord. J. Psychiatry, 2012, 66(3),183-188. http://dx.doi.org/10.3109/08039488.2011.611894
    • (2012) Nord. J. Psychiatry , vol.66 , Issue.3 , pp. 183-188
    • Yoon, H.K.1    Kim, Y.K.2    Lee, H.J.3    Kwon, D.Y.4    Kim, L.5
  • 89
    • 84867140020 scopus 로고    scopus 로고
    • Serum concentrations of CRP, IL-6, TNF-alpha and cortisol inmajor depressive disorder with melancholic or atypical features
    • Karlovic, D.; Serretti, A.; Vrkic, N.; Martinac, M.; Marcinko, D., Serum concentrations of CRP, IL-6, TNF-alpha and cortisol inmajor depressive disorder with melancholic or atypical features. Psychiatry Res., 2012, 198(1), 74-80. http://dx.doi.org/10.1016/j.psychres.2011.12.007
    • (2012) Psychiatry Res. , vol.198 , Issue.1 , pp. 74-80
    • Karlovic, D.1    Serretti, A.2    Vrkic, N.3    Martinac, M.4    Marcinko, D.5
  • 90
    • 84878237073 scopus 로고    scopus 로고
    • Evidence for a differential role ofHPA-axis function, inflammation and metabolic syndrome inmelancholic versus atypical depression
    • Lamers, F.; Vogelzangs, N.; Merikangas, K.R.; de Jonge, P.; Beekman, A.T.; Penninx, B.W. Evidence for a differential role ofHPA-axis function, inflammation and metabolic syndrome inmelancholic versus atypical depression. Mol. Psychiatry, 2013,18(6), 692-699. http://dx.doi.org/10.1038/mp.2012.144
    • (2013) Mol. Psychiatry , vol.18 , Issue.6 , pp. 692-699
    • Lamers, F.1    Vogelzangs, N.2    Merikangas, K.R.3    De Jonge, P.4    Beekman, A.T.5    Penninx, B.W.6
  • 91
    • 84878117912 scopus 로고    scopus 로고
    • The role ofimmune genes in the association between depression andinflammation: A review of recent clinical studies
    • Bufalino, C.; Hepgul, N.; Aguglia, E.; Pariante, C.M. The role ofimmune genes in the association between depression andinflammation: a review of recent clinical studies. Brain Behav.Immun., 2013, 31, 31-47. http://dx.doi.org/10.1016/j.bbi.2012.04.009
    • (2013) Brain Behav.Immun. , vol.31 , pp. 31-47
    • Bufalino, C.1    Hepgul, N.2    Aguglia, E.3    Pariante, C.M.4
  • 92
    • 0037400953 scopus 로고    scopus 로고
    • TNFB polymorphism may beassociated with schizophrenia in the Korean population
    • Jun, T.Y.; Pae, C.U.; Chae, J.H. TNFB polymorphism may beassociated with schizophrenia in the Korean population. Schizophr.Res., 2003, 61(1), 39-45. http://dx.doi.org/10.1016/S0920-9964(02)00303-1
    • (2003) Schizophr.Res. , vol.61 , Issue.1 , pp. 39-45
    • Jun, T.Y.1    Pae, C.U.2    Chae, J.H.3
  • 93
    • 76649086050 scopus 로고    scopus 로고
    • The -308 (G/A) single nucleotide polymorphism in theTNF-alpha gene and the risk of major depression in the elderly
    • Cerri, A.P.; Arosio, B.; Viazzoli, C.; Confalonieri, R.; Vergani, C.; Annoni, G. The -308 (G/A) single nucleotide polymorphism in theTNF-alpha gene and the risk of major depression in the elderly. Int. J.Ger. Psychiatry, 2010, 25(3), 219-223. http://dx.doi.org/10.1002/gps.2323
    • (2010) Int. J.Ger. Psychiatry , vol.25 , Issue.3 , pp. 219-223
    • Cerri, A.P.1    Arosio, B.2    Viazzoli, C.3    Confalonieri, R.4    Vergani, C.5    Annoni, G.6
  • 94
    • 84882925540 scopus 로고    scopus 로고
    • TNF-alpha -308G>Apolymorphism is associated with suicide attempts in majordepressive disorder
    • Kim, Y.K.; Hong, J.P.; Hwang, J.A. TNF-alpha -308G>Apolymorphism is associated with suicide attempts in majordepressive disorder. J. Affect. Disord., 2013, 150(2), 668-672. http://dx.doi.org/10.1016/j.jad.2013.03.019
    • (2013) J. Affect. Disord. , vol.150 , Issue.2 , pp. 668-672
    • Kim, Y.K.1    Hong, J.P.2    Hwang, J.A.3
  • 95
    • 71649086548 scopus 로고    scopus 로고
    • Regionallyspecificchanges in levels of tumour necrosis factor in thedorsolateral prefrontal cortex obtained postmortem from subjectswith major depressive disorder
    • Dean, B.; Tawadros, N.; Scarr, E.; Gibbons, A. S. Regionallyspecificchanges in levels of tumour necrosis factor in thedorsolateral prefrontal cortex obtained postmortem from subjectswith major depressive disorder. J. Affect. Disord., 2010, 120(1-3),245-8. http://dx.doi.org/10.1016/j.jad.2009.04.027
    • (2010) J. Affect. Disord. , vol.120 , Issue.13 , pp. 245-248
    • Dean, B.1    Tawadros, N.2    Scarr, E.3    Gibbons, A.S.4
  • 96
    • 84879410148 scopus 로고    scopus 로고
    • Different changes in cortical tumor necrosis factor-alpharelatedpathways in schizophrenia and mood disorders
    • Dean, B.; Gibbons, A.S.; Tawadros, N.; Brooks, L.; Everall, I.P.; Scarr, E. Different changes in cortical tumor necrosis factor-alpharelatedpathways in schizophrenia and mood disorders. Mol.Psychiatry 2013, 18(7), 767-773. http://dx.doi.org/10.1038/mp.2012.95
    • (2013) Mol.Psychiatry , vol.18 , Issue.7 , pp. 767-773
    • Dean, B.1    Gibbons, A.S.2    Tawadros, N.3    Brooks, L.4    Everall, I.P.5    Scarr, E.6
  • 97
    • 81855198982 scopus 로고    scopus 로고
    • Proinflammatory cytokines inthe prefrontal cortex of teenage suicide victims
    • Pandey, G.N.; Rizavi, H.S.; Ren, X. Proinflammatory cytokines inthe prefrontal cortex of teenage suicide victims. J. Psychiatry Res.,2012, 46(1), 57-63. http://dx.doi.org/10.1016/j.jpsychires.2011.08.006
    • (2012) J. Psychiatry Res. , vol.46 , Issue.1 , pp. 57-63
    • Pandey, G.N.1    Rizavi, H.S.2    Ren, X.3
  • 98
    • 84887617892 scopus 로고    scopus 로고
    • The role ofinflammatory cytokines in suicidal behavior: A systematic review
    • Serafini, G.; Pompili, M.; Elena Seretti, M. The role ofinflammatory cytokines in suicidal behavior: a systematic review. Eur. Neuropsychopharmacol., 2013, 23(12), 1672-1686. http://dx.doi.org/10.1016/j.euroneuro.2013.06.002
    • (2013) Eur. Neuropsychopharmacol. , vol.23 , Issue.12 , pp. 1672-1686
    • Serafini, G.1    Pompili, M.2    Elena Seretti, M.3
  • 99
    • 84876109471 scopus 로고    scopus 로고
    • Suicidal ideation isassociated with elevated inflammation in patients with majordepressive disorder
    • O'Donovan, A.; Rush, G.; Hoatam, G. Suicidal ideation isassociated with elevated inflammation in patients with majordepressive disorder. Depress Anxiety, 2013, 30(4), 307-314. http://dx.doi.org/10.1002/da.22087
    • (2013) Depress Anxiety , vol.30 , Issue.4 , pp. 307-314
    • O'donovan, A.1    Rush, G.2    Hoatam, G.3
  • 101
    • 38749084587 scopus 로고    scopus 로고
    • Differences in cytokines betweennon-suicidal patients and suicidal patients in major depression
    • Kim, Y.K.; Lee, S.W.; Kim, S.H. Differences in cytokines betweennon-suicidal patients and suicidal patients in major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2008, 32(2), 356-361. http://dx.doi.org/10.1016/j.pnpbp.2007.08.041
    • (2008) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.32 , Issue.2 , pp. 356-361
    • Kim, Y.K.1    Lee, S.W.2    Kim, S.H.3
  • 102
    • 33846641772 scopus 로고    scopus 로고
    • Childhood maltreatment predicts adult inflammation in a lifecoursestudy
    • Danese, A.; Pariante, C.M.; Caspi, A.; Taylor, A.; Poulton, R. Childhood maltreatment predicts adult inflammation in a lifecoursestudy. Proc. Natl. Acad. Sci. U S A, 2007, 104(4), 1319-1324. http://dx.doi.org/10.1073/pnas.0610362104
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , Issue.4 , pp. 1319-1324
    • Danese, A.1    Pariante, C.M.2    Caspi, A.3    Taylor, A.4    Poulton, R.5
  • 103
    • 84875273658 scopus 로고    scopus 로고
    • Associationof elevated cytokines with childhood adversity in a sample ofhealthy adults
    • Hartwell, K.J.; Moran-Santa Maria, M.M.; Twal, W.O. Associationof elevated cytokines with childhood adversity in a sample ofhealthy adults. J. Psychiatr. Res., 2013, 47(5), 604-610. http://dx.doi.org/10.1016/j.jpsychires.2013.01.008
    • (2013) J. Psychiatr. Res. , vol.47 , Issue.5 , pp. 604-610
    • Hartwell, K.J.1    Moran-Santa Maria, M.M.2    Twal, W.O.3
  • 105
    • 80054745701 scopus 로고    scopus 로고
    • The effect of antidepressantmedication treatment on serum levels of inflammatory cytokines: Ameta-analysis
    • Hannestad, J.; DellaGioia, N.; Bloch, M. The effect of antidepressantmedication treatment on serum levels of inflammatory cytokines: Ameta-analysis. Neuropsychopharmacology, 2011, 36(12), 2452-2459. http://dx.doi.org/10.1038/npp.2011.132
    • (2011) Neuropsychopharmacology , vol.36 , Issue.12 , pp. 2452-2459
    • Hannestad, J.1    Dellagioia, N.2    Bloch, M.3
  • 106
    • 0033975012 scopus 로고    scopus 로고
    • Cytokine production and treatment response in major depressivedisorder
    • Lanquillon, S.; Krieg, J.C.; Bening-Abu-Shach, U.; Vedder, H. Cytokine production and treatment response in major depressivedisorder. Neuropsychopharmacology, 2000, 22(4), 370-379. http://dx.doi.org/10.1016/S0893-133X(99)00134-7
    • (2000) Neuropsychopharmacology , vol.22 , Issue.4 , pp. 370-379
    • Lanquillon, S.1    Krieg, J.C.2    Bening-Abu-shach, U.3    Vedder, H.4
  • 107
    • 0346914336 scopus 로고    scopus 로고
    • Raised plasma levels of tumor necrosis factor alpha in patients withdepression: Normalization during electroconvulsive therapy
    • Hestad, K.A.; Tonseth, S.; Stoen, C.D.; Ueland, T.; Aukrust, P. Raised plasma levels of tumor necrosis factor alpha in patients withdepression: normalization during electroconvulsive therapy. J.ECT, 2003, 19(4), 183-188. http://dx.doi.org/10.1097/00124509-200312000-00002
    • (2003) J.ECT , vol.19 , Issue.4 , pp. 183-188
    • Hestad, K.A.1    Tonseth, S.2    Stoen, C.D.3    Ueland, T.4    Aukrust, P.5
  • 108
    • 0347604853 scopus 로고    scopus 로고
    • Increasedserum tumor necrosis factor-alpha levels and treatment response inmajor depressive disorder
    • Tuglu, C.; Kara, S.H.; Caliyurt, O.; Vardar, E.; Abay, E. Increasedserum tumor necrosis factor-alpha levels and treatment response inmajor depressive disorder. Psychopharmacology (Berl), 2003,170(4), 429-433. http://dx.doi.org/10.1007/s00213-003-1566-z
    • (2003) Psychopharmacology (Berl) , vol.170 , Issue.4 , pp. 429-433
    • Tuglu, C.1    Kara, S.H.2    Caliyurt, O.3    Vardar, E.4    Abay, E.5
  • 109
    • 84870388281 scopus 로고    scopus 로고
    • Venlafaxine inhibits the upregulation ofplasma tumor necrosis factor-alpha (TNF-alpha) in the Chinesepatients with major depressive disorder: A prospective longitudinalstudy
    • Li, Z.; Qi, D.; Chen, J. Venlafaxine inhibits the upregulation ofplasma tumor necrosis factor-alpha (TNF-alpha) in the Chinesepatients with major depressive disorder: a prospective longitudinalstudy. Psychoneuroendocrinology, 2013, 38(1), 107-114. http://dx.doi.org/10.1016/j.psyneuen.2012.05.005
    • (2013) Psychoneuroendocrinology , vol.38 , Issue.1 , pp. 107-114
    • Li, Z.1    Qi, D.2    Chen, J.3
  • 110
    • 0346963279 scopus 로고    scopus 로고
    • Anti- and pro-inflammatory considerations inantidepressant use during medical illness: Bupropion lowers andmirtazapine increases circulating tumor necrosis factor-alpha levels
    • Kast, R.E. Anti- and pro-inflammatory considerations inantidepressant use during medical illness: bupropion lowers andmirtazapine increases circulating tumor necrosis factor-alpha levels. Gen. Hosp. Psychiatry, 2003, 25(6), 495-496. http://dx.doi.org/10.1055/s-2002-36390
    • (2003) Gen. Hosp. Psychiatry , vol.25 , Issue.6 , pp. 495-496
    • Kast, R.E.1
  • 111
    • 0036869374 scopus 로고    scopus 로고
    • Body weight, the tumor necrosis factor system, andleptin production during treatment with mirtazapine or venlafaxine
    • Kraus, T.; Haack, M.; Schuld, A.; Hinze-Selch, D.; Koethe, D.; Pollmacher, T. Body weight, the tumor necrosis factor system, andleptin production during treatment with mirtazapine or venlafaxine. Pharmacopsychiatry, 2002, 35(6), 220-225. http://dx.doi.org/10.1055/s-2002-36390
    • (2002) Pharmacopsychiatry , vol.35 , Issue.6 , pp. 220-225
    • Kraus, T.1    Haack, M.2    Schuld, A.3    Hinze-Selch, D.4    Koethe, D.5    Pollmacher, T.6
  • 112
    • 33845213789 scopus 로고    scopus 로고
    • Plasma cytokine profiles in depressed patients who fail to respondto selective serotonin reuptake inhibitor therapy
    • O'Brien, S.M.; Scully, P.; Fitzgerald, P.; Scott, L.V.; Dinan, T.G. Plasma cytokine profiles in depressed patients who fail to respondto selective serotonin reuptake inhibitor therapy. J. Psychiatr. Res.,2007, 41(34), 326-331. http://dx.doi.org/10.1016/j.jpsychires.2006.05.013
    • (2007) J. Psychiatr. Res. , vol.41 , Issue.34 , pp. 326-331
    • O'brien, S.M.1    Scully, P.2    Fitzgerald, P.3    Scott, L.V.4    Dinan, T.G.5
  • 113
    • 77952746394 scopus 로고    scopus 로고
    • Pharmacology of TNF blockade in rheumatoidarthritis and other chronic inflammatory diseases
    • Taylor, P.C. Pharmacology of TNF blockade in rheumatoidarthritis and other chronic inflammatory diseases. Curr. Opin.Pharmacol., 2010, 10(3), 308-315. http://dx.doi.org/10.1016/j.coph.2010.01.005
    • (2010) Curr. Opin.Pharmacol. , vol.10 , Issue.3 , pp. 308-315
    • Taylor, P.C.1
  • 114
    • 84880395212 scopus 로고    scopus 로고
    • Effects of longtermetanercept treatment on anxiety- and depression-likeneurobehaviors in rats
    • Bayramgurler, D.; Karson, A.; Ozer, C.; Utkan, T. Effects of longtermetanercept treatment on anxiety- and depression-likeneurobehaviors in rats. Physiol. Behav., 2013, 119, 145-148. http://dx.doi.org/10.1016/j.physbeh.2013.06.010
    • (2013) Physiol. Behav. , vol.119 , pp. 145-148
    • Bayramgurler, D.1    Karson, A.2    Ozer, C.3    Utkan, T.4
  • 115
    • 84875277496 scopus 로고    scopus 로고
    • Antidepressant effects of TNF-alpha blockade in an animal modelof depression
    • Krugel, U.; Fischer, J.; Radicke, S.; Sack, U.; Himmerich, H. Antidepressant effects of TNF-alpha blockade in an animal modelof depression. J. Psychiatr. Res., 2013, 47(5), 611-616. http://dx.doi.org/10.1016/j.jpsychires.2013.01.007
    • (2013) J. Psychiatr. Res. , vol.47 , Issue.5 , pp. 611-616
    • Krugel, U.1    Fischer, J.2    Radicke, S.3    Sack, U.4    Himmerich, H.5
  • 116
    • 84876443867 scopus 로고    scopus 로고
    • Chronic administration of infliximab (TNF-alpha inhibitor)decreases depression and anxiety-like behaviour in rat model ofchronic mild stress
    • Karson, A.; Demirtas, T.; Bayramgurler, D.; Balci, F.; Utkan, T. Chronic administration of infliximab (TNF-alpha inhibitor)decreases depression and anxiety-like behaviour in rat model ofchronic mild stress. Basic Clin. Pharmacol. Toxicol., 2013, 112(5),335-340. http://dx.doi.org/10.1111/bcpt.12037
    • (2013) Basic Clin. Pharmacol. Toxicol. , vol.112 , Issue.5 , pp. 335-340
    • Karson, A.1    Demirtas, T.2    Bayramgurler, D.3    Balci, F.4    Utkan, T.5
  • 118
    • 65249156122 scopus 로고    scopus 로고
    • Interferon-gamma and tumornecrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in micein response to bacillus Calmette-Guerin
    • O'Connor, J.C.; Andre, C.; Wang, Y. Interferon-gamma and tumornecrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in micein response to bacillus Calmette-Guerin. J. Neurosci., 2009, 29(13),4200-4209. http://dx.doi.org/10.1523/JNEUROSCI.5032-08.2009
    • (2009) J. Neurosci. , vol.29 , Issue.13 , pp. 4200-4209
    • O'connor, J.C.1    Andre, C.2    Wang, Y.3
  • 119
    • 84857036853 scopus 로고    scopus 로고
    • Infliximab, a TNF-alpha antagonisttreatment in patients with ankylosing spondylitis: The impact ondepression, anxiety and quality of life level
    • Ertenli, I.; Ozer, S.; Kiraz, S. Infliximab, a TNF-alpha antagonisttreatment in patients with ankylosing spondylitis: The impact ondepression, anxiety and quality of life level. Rheumatol. Int., 2012,32(2), 323-330. http://dx.doi.org/10.1007/s00296-010-1616-x
    • (2012) Rheumatol. Int. , vol.32 , Issue.2 , pp. 323-330
    • Ertenli, I.1    Ozer, S.2    Kiraz, S.3
  • 120
    • 84875427364 scopus 로고    scopus 로고
    • Depressive symptoms inCrohn's disease: Relationship with immune activation and tryptophanavailability
    • Guloksuz, S.; Wichers, M.; Kenis, G. Depressive symptoms inCrohn's disease: relationship with immune activation and tryptophanavailability. PloS One, 2013, 8(3), e60435. http://dx.doi.org/10.1371/journal.pone.0060435
    • (2013) Plos One , vol.8 , Issue.3 , pp. 60435
    • Guloksuz, S.1    Wichers, M.2    Kenis, G.3
  • 121
    • 22844451589 scopus 로고    scopus 로고
    • The impact of majordepressive disorder on the short- and long-term outcome of Crohn'sdisease treatment with infliximab
    • Persoons, P.; Vermeire, S.; Demyttenaere, K. The impact of majordepressive disorder on the short- and long-term outcome of Crohn'sdisease treatment with infliximab. Aliment. Pharmacol. Ther.,2005, 22(2), 101-110. http://dx.doi.org/10.1111/j.1365-2036.2005.02535.x
    • (2005) Aliment. Pharmacol. Ther. , vol.22 , Issue.2 , pp. 101-110
    • Persoons, P.1    Vermeire, S.2    Demyttenaere, K.3
  • 122
    • 34249085886 scopus 로고    scopus 로고
    • Crohn's disease,fatigue, and infliximab: Is there a role for cytokines in thepathogenesis of fatigue? World
    • Minderhoud, I.M.; Samsom, M.; Oldenburg, B. Crohn's disease,fatigue, and infliximab: is there a role for cytokines in thepathogenesis of fatigue? World J. Gastroenterol., 2007, 13(14),2089-2093.
    • (2007) J. Gastroenterol. , vol.13 , Issue.14 , pp. 2089-2093
    • Minderhoud, I.M.1    Samsom, M.2    Oldenburg, B.3
  • 124
    • 53549118009 scopus 로고    scopus 로고
    • Infliximab rescue of efalizumabwithdrawal flare and psoriasis-precipitated depression
    • Yip, L.; Harrison, S.; Foley, P. Infliximab rescue of efalizumabwithdrawal flare and psoriasis-precipitated depression. Australas. J.Dermatol., 2008, 49(4), 250-251. http://dx.doi.org/10.1111/j.1440-0960.2008.00487.x
    • (2008) Australas. J.Dermatol. , vol.49 , Issue.4 , pp. 250-251
    • Yip, L.1    Harrison, S.2    Foley, P.3
  • 125
    • 51649114225 scopus 로고    scopus 로고
    • Fatigue inpatients with advanced cancer: A pilot study of an intervention withinfliximab
    • Tookman, A.J.; Jones, C.L.; DeWitte, M.; Lodge, P.J. Fatigue inpatients with advanced cancer: a pilot study of an intervention withinfliximab. Support. Care Cancer, 2008, 16(10), 1131-1140. http://dx.doi.org/10.1007/s00520-008-0429-x
    • (2008) Support. Care Cancer , vol.16 , Issue.10 , pp. 1131-1140
    • Tookman, A.J.1    Jones, C.L.2    Dewitte, M.3    Lodge, P.J.4
  • 126
    • 84878129547 scopus 로고    scopus 로고
    • Transcriptional signaturesrelated to glucose and lipid metabolism predict treatment responseto the tumor necrosis factor antagonist infliximab in patients withtreatment-resistant depression
    • Mehta, D.; Raison, C.L.; Woolwine, B.J. Transcriptional signaturesrelated to glucose and lipid metabolism predict treatment responseto the tumor necrosis factor antagonist infliximab in patients withtreatment-resistant depression. Brain Behav. Immun., 2013, 31,205-215. http://dx.doi.org/10.1016/j.bbi.2013.04.004
    • (2013) Brain Behav. Immun. , vol.31 , pp. 205-215
    • Mehta, D.1    Raison, C.L.2    Woolwine, B.J.3
  • 127
    • 84872500205 scopus 로고    scopus 로고
    • Candidate genes expressionprofile associated with antidepressants response in the GENDEPstudy: Differentiating between baseline 'predictors' and longitudinal'targets'
    • Cattaneo, A.; Gennarelli, M.; Uher, R. Candidate genes expressionprofile associated with antidepressants response in the GENDEPstudy: differentiating between baseline 'predictors' and longitudinal'targets'. Neuropsychopharmacology, 2013, 38(3), 377-385. http://dx.doi.org/10.1038/npp.2012.191
    • (2013) Neuropsychopharmacology , vol.38 , Issue.3 , pp. 377-385
    • Cattaneo, A.1    Gennarelli, M.2    Uher, R.3
  • 128
    • 84884210609 scopus 로고    scopus 로고
    • Tumor necrosisfactor and its targets in the inflammatory cytokine pathway areidentified as putative transcriptomic biomarkers for escitalopramresponse
    • Powell, T.R.; Schalkwyk, L.C.; Heffernan, A.L. Tumor necrosisfactor and its targets in the inflammatory cytokine pathway areidentified as putative transcriptomic biomarkers for escitalopramresponse. Eur. Neuropsychopharmacol., 2013, 23(9), 1105-1114. http://dx.doi.org/10.1016/j.euroneuro.2012.09.009
    • (2013) Eur. Neuropsychopharmacol. , vol.23 , Issue.9 , pp. 1105-1114
    • Powell, T.R.1    Schalkwyk, L.C.2    Heffernan, A.L.3
  • 129
    • 78751681222 scopus 로고    scopus 로고
    • Improvements in patient-reported outcomes, symptomsof depression and anxiety, and their association with clinicalremission among patients with moderate-to-severe active earlyrheumatoid arthritis
    • Kekow, J.; Moots, R.; Khandker, R.; Melin, J.; Freundlich, B.; Singh, A. Improvements in patient-reported outcomes, symptomsof depression and anxiety, and their association with clinicalremission among patients with moderate-to-severe active earlyrheumatoid arthritis. Rheumatology (Oxford), 2011, 50(2), 401-409. http://dx.doi.org/10.1093/rheumatology/keq327
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.2 , pp. 401-409
    • Kekow, J.1    Moots, R.2    Khandker, R.3    Melin, J.4    Freundlich, B.5    Singh, A.6
  • 130
    • 84891853644 scopus 로고    scopus 로고
    • Open-labelobservation of addition of etanercept versus a conventional diseasemodifyingantirheumatic drug in subjects with active rheumatoidarthritis despite methotrexate therapy in the Latin American region
    • Machado, D.A.; Guzman, R.M.; Xavier, R.M. Open-labelobservation of addition of etanercept versus a conventional diseasemodifyingantirheumatic drug in subjects with active rheumatoidarthritis despite methotrexate therapy in the Latin American region. J. Clin. Rheumatol., 2014, 20(1), 25-33. http://dx.doi.org/10.1097/RHU.0000000000000055
    • (2014) J. Clin. Rheumatol. , vol.20 , Issue.1 , pp. 25-33
    • Machado, D.A.1    Guzman, R.M.2    Xavier, R.M.3
  • 131
    • 44049097512 scopus 로고    scopus 로고
    • Patient-reportedoutcomes and health-care resource utilization in patients withpsoriasis treated with etanercept: Continuous versus interruptedtreatment
    • Gelfand, J.M.; Kimball, A.B.; Mostow, E.N. Patient-reportedoutcomes and health-care resource utilization in patients withpsoriasis treated with etanercept: continuous versus interruptedtreatment. Value Health, 2008, 11(3), 400-407. http://dx.doi.org/10.1111/j.1524-4733.2007.00251.x
    • (2008) Value Health , vol.11 , Issue.3 , pp. 400-407
    • Gelfand, J.M.1    Kimball, A.B.2    Mostow, E.N.3
  • 132
    • 70449492883 scopus 로고    scopus 로고
    • Improvements in patientreportedoutcomes in moderate-to-severe psoriasis patientsreceiving continuous or paused etanercept treatment over 54 weeks:The CRYSTEL study
    • Dauden, E.; Griffiths, C.E.; Ortonne, J. P. Improvements in patientreportedoutcomes in moderate-to-severe psoriasis patientsreceiving continuous or paused etanercept treatment over 54 weeks:the CRYSTEL study. J. Eur. Acad. Dermatol. Venereol., 2009, 23(12), 1374-1382. http://dx.doi.org/10.1111/j.1468-3083.2009.03321.x
    • (2009) J. Eur. Acad. Dermatol. Venereol. , vol.23 , Issue.12 , pp. 1374-1382
    • Dauden, E.1    Griffiths, C.E.2    Ortonne, J.P.3
  • 133
    • 29844440963 scopus 로고    scopus 로고
    • Etanercept and clinical outcomes,fatigue, and depression in psoriasis: Double-blind placebocontrolledrandomised phase III trial
    • Tyring, S.; Gottlieb, A.; Papp, K. Etanercept and clinical outcomes,fatigue, and depression in psoriasis: double-blind placebocontrolledrandomised phase III trial. Lancet, 2006, 367(9504), 29-35. http://dx.doi.org/10.1016/S0140-6736(05)67763-X
    • (2006) Lancet , vol.367 , Issue.9504 , pp. 29-35
    • Tyring, S.1    Gottlieb, A.2    Papp, K.3
  • 134
    • 36148988466 scopus 로고    scopus 로고
    • Effects of etanercept therapyon fatigue and symptoms of depression in subjects treated formoderate to severe plaque psoriasis for up to 96 weeks
    • Krishnan, R.; Cella, D.; Leonardi, C. Effects of etanercept therapyon fatigue and symptoms of depression in subjects treated formoderate to severe plaque psoriasis for up to 96 weeks. Br. J.Dermatol., 2007, 157(6), 1275-1277. http://dx.doi.org/10.1111/j.1365-2133.2007.08205.x
    • (2007) Br. J.Dermatol. , vol.157 , Issue.6 , pp. 1275-1277
    • Krishnan, R.1    Cella, D.2    Leonardi, C.3
  • 135
    • 84867575056 scopus 로고    scopus 로고
    • Self-reported healthoutcomes in patients with psoriasis and psoriatic arthritisrandomized to two etanercept regimens
    • Gniadecki, R.; Robertson, D.; Molta, C.T. Self-reported healthoutcomes in patients with psoriasis and psoriatic arthritisrandomized to two etanercept regimens. J. Eur. Acad. Dermatol.Venereol., 2012, 26(11), 1436-1443. http://dx.doi.org/10.1111/j.1468-3083.2011.04308.x
    • (2012) J. Eur. Acad. Dermatol.Venereol. , vol.26 , Issue.11 , pp. 1436-1443
    • Gniadecki, R.1    Robertson, D.2    Molta, C.T.3
  • 136
    • 84899477303 scopus 로고    scopus 로고
    • Disease characteristics in patients with and without psoriaticarthritis treated with etanercept
    • Papp, K.; Poulin, Y.; Vieira, A.; Shelton, J.; Poulin-Costello, M. Disease characteristics in patients with and without psoriaticarthritis treated with etanercept. J. Eur. Acad. Dermatol. Venereol.,2014, 28(5), 581-589. http://dx.doi.org/10.1111/jdv.12138
    • (2014) J. Eur. Acad. Dermatol. Venereol. , vol.28 , Issue.5 , pp. 581-589
    • Papp, K.1    Poulin, Y.2    Vieira, A.3    Shelton, J.4    Poulin-Costello, M.5
  • 137
    • 58149388237 scopus 로고    scopus 로고
    • Effects of adalimumabmaintenance therapy on health-related quality of life of patientswith Crohn's disease: Patient-reported outcomes of the CHARMtrial
    • Loftus, E.V.; Feagan, B.G.; Colombel, J.F. Effects of adalimumabmaintenance therapy on health-related quality of life of patientswith Crohn's disease: patient-reported outcomes of the CHARMtrial. Am. J. Gastroenterol., 2008, 103(12), 3132-3141. http://dx.doi.org/10.1111/j.1572-0241.2008.02175.x
    • (2008) Am. J. Gastroenterol. , vol.103 , Issue.12 , pp. 3132-3141
    • Loftus, E.V.1    Feagan, B.G.2    Colombel, J.F.3
  • 138
    • 77950594947 scopus 로고    scopus 로고
    • The effect of adalimumabon reducing depression symptoms in patients with moderate tosevere psoriasis: A randomized clinical trial
    • Menter, A.; Augustin, M.; Signorovitch, J. The effect of adalimumabon reducing depression symptoms in patients with moderate tosevere psoriasis: A randomized clinical trial. J. Am. Acad. Dermatol.,2010, 62(5), 812-818. http://dx.doi.org/10.1016/j.jaad.2009.07.022
    • (2010) J. Am. Acad. Dermatol. , vol.62 , Issue.5 , pp. 812-818
    • Menter, A.1    Augustin, M.2    Signorovitch, J.3
  • 139
    • 84879690397 scopus 로고    scopus 로고
    • The effect ofTNF-alpha blockers on psychometric measures in ankylosingspondylitis patients: A preliminary observation
    • Arisoy, O.; Bes, C.; Cifci, C.; Sercan, M.; Soy, M. The effect ofTNF-alpha blockers on psychometric measures in ankylosingspondylitis patients: a preliminary observation. Rheumatol. Int.,2013, 33(7), 1855-1864. http://dx.doi.org/10.1007/s00296-013-2671-x
    • (2013) Rheumatol. Int. , vol.33 , Issue.7 , pp. 1855-1864
    • Arisoy, O.1    Bes, C.2    Cifci, C.3    Sercan, M.4    Soy, M.5
  • 140
    • 84897046481 scopus 로고    scopus 로고
    • Association of TNF-alphapolymorphism with prediction of response to TNF blockers inspondyloarthritis and inflammatory bowel disease: A meta-analysis
    • Tong, Q.; Zhao, L.; Qian, X.D. Association of TNF-alphapolymorphism with prediction of response to TNF blockers inspondyloarthritis and inflammatory bowel disease: a meta-analysis. Pharmacogenom. J, 2013, 14(14), 1691-1700. http://dx.doi.org/10.2217/pgs.13.146
    • (2013) Pharmacogenom. J , vol.14 , Issue.14 , pp. 1691-1700
    • Tong, Q.1    Zhao, L.2    Qian, X.D.3
  • 141
    • 77950632641 scopus 로고    scopus 로고
    • Associations betweentumor necrosis factor-alpha (TNF-alpha) -308 and -238 G/Apolymorphisms and shared epitope status and responsiveness to TNF-alpha blockers in rheumatoid arthritis: A metaanalysis update
    • Lee, Y.H.; Ji, J.D.; Bae, S.C.; Song, G.G. Associations betweentumor necrosis factor-alpha (TNF-alpha) -308 and -238 G/Apolymorphisms and shared epitope status and responsiveness to TNF-alpha blockers in rheumatoid arthritis: a metaanalysis update.J. Rheumatol., 2010, 37(4), 740-746. http://dx.doi.org/10.3899/jrheum.090707
    • (2010) J. Rheumatol. , vol.37 , Issue.4 , pp. 740-746
    • Lee, Y.H.1    Ji, J.D.2    Bae, S.C.3    Song, G.G.4
  • 142
    • 84870661648 scopus 로고    scopus 로고
    • Effects ofpolymorphisms in TRAILR1 and TNFR1A on the response to anti-TNF therapies in patients with rheumatoid and psoriatic arthritis
    • Morales-Lara, M.J.; Canete, J.D.; Torres-Moreno, D. Effects ofpolymorphisms in TRAILR1 and TNFR1A on the response to anti-TNF therapies in patients with rheumatoid and psoriatic arthritis. Joint Bone Spine, 2012, 79(6), 591-596. http://dx.doi.org/10.1016/j.jbspin.2012.02.003
    • (2012) Joint Bone Spine , vol.79 , Issue.6 , pp. 591-596
    • Morales-Lara, M.J.1    Canete, J.D.2    Torres-Moreno, D.3
  • 143
    • 80455131338 scopus 로고    scopus 로고
    • Genetic and genomic predictors ofanti-TNF response
    • Prajapati, R.; Plant, D.; Barton, A. Genetic and genomic predictors ofanti-TNF response. Pharmacogenom. J., 2011, 12(11), 1571-1585. http://dx.doi.org/10.2217/pgs.11.114
    • (2011) Pharmacogenom. J. , vol.12 , Issue.11 , pp. 1571-1585
    • Prajapati, R.1    Plant, D.2    Barton, A.3
  • 144
    • 58449126626 scopus 로고    scopus 로고
    • Anti-tumornecrosis factor-alpha therapy is associated with less frequent moodand anxiety disorders in patients with rheumatoid arthritis
    • Uguz, F.; Akman, C.; Kucuksarac, S.; Tufekci, O. Anti-tumornecrosis factor-alpha therapy is associated with less frequent moodand anxiety disorders in patients with rheumatoid arthritis. PsychiatryClin. Neurosci., 2009, 63(1), 50-55. http://dx.doi.org/10.1111/j.1440-1819.2008.01905.x
    • (2009) Psychiatryclin. Neurosci. , vol.63 , Issue.1 , pp. 50-55
    • Uguz, F.1    Akman, C.2    Kucuksarac, S.3    Tufekci, O.4
  • 145
    • 84890235819 scopus 로고    scopus 로고
    • Innovative solutions to novel drugdevelopment in mental health
    • Insel, T.R.; Voon, V.; Nye, J.S. Innovative solutions to novel drugdevelopment in mental health. Neurosci. Biobehav. Rev., 2013,37(Pt 1), 2438-2444. http://dx.doi.org/10.1016/j.neubiorev.2013.03.022
    • (2013) Neurosci. Biobehav. Rev. , vol.37 , pp. 2438-2444
    • Insel, T.R.1    Voon, V.2    Nye, J.S.3
  • 146
    • 84870344600 scopus 로고    scopus 로고
    • Disease activity and cognition inrheumatoid arthritis: An open label pilot study
    • Raftery, G.; He, J.; Pearce, R. Disease activity and cognition inrheumatoid arthritis: an open label pilot study. Arthritis Res. Ther.,2012, 14(6), R263. http://dx.doi.org/10.1186/ar4108
    • (2012) Arthritis Res. Ther. , vol.14 , Issue.6 , pp. 263
    • Raftery, G.1    He, J.2    Pearce, R.3
  • 147
    • 77955034395 scopus 로고    scopus 로고
    • Everyday cognitive failure in sarcoidosis:The prevalence and the effect of anti-TNF-alpha treatment
    • Elfferich, M.D.; Nelemans, P.J.; Ponds, R.W.; De Vries, J.; Wijnen, P.A.; Drent, M. Everyday cognitive failure in sarcoidosis:the prevalence and the effect of anti-TNF-alpha treatment. Respiration, 2010, 80(3), 212-219. http://dx.doi.org/10.1159/000314225
    • (2010) Respiration , vol.80 , Issue.3 , pp. 212-219
    • Elfferich, M.D.1    Nelemans, P.J.2    Ponds, R.W.3    De Vries, J.4    Wijnen, P.A.5    Drent, M.6
  • 148
    • 49949104408 scopus 로고    scopus 로고
    • Rapid improvement in verbal fluency andaphasia following perispinal etanercept in Alzheimer's disease
    • Tobinick, E.L.; Gross, H. Rapid improvement in verbal fluency andaphasia following perispinal etanercept in Alzheimer's disease. BMC Neurol., 2008, 8, 27. http://dx.doi.org/10.1186/1471-2377-8-27
    • (2008) BMC Neurol. , vol.8 , pp. 27
    • Tobinick, E.L.1    Gross, H.2
  • 150
    • 84898752877 scopus 로고    scopus 로고
    • The NIMH Research Domain Criteria (RDoC) Project:Precision medicine for psychiatry
    • Insel, T.R. The NIMH Research Domain Criteria (RDoC) Project:precision medicine for psychiatry. Am. J. Psychiatry, 2014, 171(4),395-397. http://dx.doi.org/10.1176/appi.ajp.2014.14020138
    • (2014) Am. J. Psychiatry , vol.171 , Issue.4 , pp. 395-397
    • Insel, T.R.1


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