Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns

Journal of Neurogenetics

Volumn 29, Issue 2-3, 2015, Pages 135-143

  Wise, Alexandria ^a   Tenezaca, Luis ^a   Fernandez, Robert W ^b   Schatoff, Emma ^a   Flores, Julian ^a   Ueda, Atsushi ^c   Zhong, Xiaotian ^c   Wu, Chun Fang ^c   Simon, Anne F ^d   Venkatesh, Tadmiri ^a  

^a CITY COLLEGE OF NEW YORK   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Autism spectrum disorder; Drosophila; neurobeachin; neuromuscular junction; rugose; synaptic development

Indexed keywords

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EVOKED RESPONSE; GENE; IMMUNOCYTOCHEMISTRY; LOCOMOTION; LOSS OF FUNCTION MUTATION; MALE; MOUSE; MUTANT DROSOPHILA; NEUROBEACHIN GENE; NEUROMUSCULAR SYNAPSE; NEUROMUSCULAR TRANSMISSION; NONHUMAN; PERISTALSIS; PRIORITY JOURNAL; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL STRESS; SYNAPTIC TRANSMISSION; SYNAPTOSOME; T-MAZE TEST; ANIMAL; ANIMAL BEHAVIOR; DROSOPHILA MELANOGASTER; GENETICS; METABOLISM; MOTOR ACTIVITY; MUTATION; NEUROMUSCULAR JUNCTION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SYNAPSE; TRANSGENIC ANIMAL;

CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; DROSOPHILA PROTEIN; RUGOSE PROTEIN, DROSOPHILA;

A KINASE ANCHOR PROTEINS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; LOCOMOTION; MOTOR ACTIVITY; MUTATION; NEUROMUSCULAR JUNCTION; SIGNAL TRANSDUCTION; SOCIAL BEHAVIOR; SYNAPSES;

EID: 84946556522     PISSN: 01677063     EISSN: 15635260     Source Type: Journal    
DOI: 10.3109/01677063.2015.1064916     Document Type: Article

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