Discriminating neural representations of physical and social pains: How multivariate statistics challenge the “shared representation” theory of pain

Journal of Neurophysiology

Volumn 114, Issue 5, 2015, Pages 2558-2560

  Rogachov, A ^a,b   Cheng, J C ^a,b   DeSouza, D D ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

FMRI; Multivariate statistics; Pain; Social rejection

Indexed keywords

ARTICLE; BRAIN REGION; ELECTROENCEPHALOGRAM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; MULTIVARIATE ANALYSIS; PAIN; PAIN ASSESSMENT; PAIN MEASUREMENT; PHYSICAL DISEASE; PHYSICAL PAIN; PRIORITY JOURNAL; SHARED REPRESENTATION THEORY; SOCIAL EXCLUSION; SOCIAL REJECTION; THEORY; BRAIN; BRAIN MAPPING; NUCLEAR MAGNETIC RESONANCE IMAGING;

BRAIN; BRAIN MAPPING; HUMANS; MAGNETIC RESONANCE IMAGING; PAIN;

EID: 84946423257     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00075.2015     Document Type: Article

References (7)

1. Eisenberger NI. The pain of social disconnection: examining the shared neural underpinnings of physical and social pain. Nat Rev Neurosci 13: 421–434, 2012.
2. Eisenberger NI, Lieberman MD, Williams KD. Does rejection hurt? An FMRI study of social exclusion. Science 302: 290–292, 2003.
3. Haufe S, Meinecke F, Gorgen K, Dahne S, Haynes JD, Blankertz B, Biessmann F. On the interpretation of weight vectors of linear models in multivariate neuroimaging. Neuroimage 87: 96–110, 2014.
4. Macdonald G, Leary MR. Why does social exclusion hurt? The relationship between social and physical pain. Psychol Bull 131: 202–223, 2005.
5. Sheth SA, Mian MK, Patel SR, Asaad WF, Williams ZM, Dougherty DD, Bush G, Eskandar EN. Human dorsal anterior cingulate cortex neurons mediate ongoing behavioural adaptation. Nature 488: 218–221, 2012.
6. Truini A, Garcia-Larrea L, Cruccu G. Reappraising neuropathic pain in humans–how symptoms help disclose mechanisms. Nat Rev Neurol 9: 572–582, 2013.
7. Woo CW, Koban L, Kross E, Lindquist MA, Banich MT, Ruzic L, Andrews-Hanna JR, Wager TD. Separate neural representations for physical pain and social rejection. Nat Commun 5: 5380, 2014.