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Volumn 54, Issue 10, 2015, Pages 1737-1746

The impact of complete chemotherapy stop on the overall survival of patients with advanced colorectal cancer in first-line setting: A meta-analysis of randomized trials

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ANTINEOPLASTIC AGENT;

EID: 84946228300     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2015.1044022     Document Type: Article
Times cited : (18)

References (44)
  • 2
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, Homerin M, Hmissi A, Cassidy J, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol. 2000; 18 (16): 2938-47.
    • (2000) J Clin Oncol , vol.18 , Issue.16 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3    Homerin, M.4    Hmissi, A.5    Cassidy, J.6
  • 3
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet. 2000; 355 (9209): 1041-7.
    • (2000) Lancet , vol.355 , Issue.9209 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3    Navarro, M.4    James, R.D.5    Karasek, P.6
  • 4
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, Andre T, Achille E, Lledo G, Flesh M, Mery-Mignard D, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004; 22 (2): 229-37.
    • (2004) J Clin Oncol , vol.22 , Issue.2 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3    Lledo, G.4    Flesh, M.5    Mery-Mignard, D.6
  • 5
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 2004; 22 (1): 23-30.
    • (2004) J Clin Oncol , vol.22 , Issue.1 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3    Fuchs, C.S.4    Ramanathan, R.K.5    Williamson, S.K.6
  • 6
    • 42949150908 scopus 로고    scopus 로고
    • Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer
    • Cassidy J, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol. 2008; 26 (12): 2006-12.
    • (2008) J Clin Oncol , vol.26 , Issue.12 , pp. 2006-2012
    • Cassidy, J.1    Clarke, S.2    Diaz-Rubio, E.3    Scheithauer, W.4    Figer, A.5    Wong, R.6
  • 7
    • 33746805967 scopus 로고    scopus 로고
    • Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup Trial
    • Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup Trial. J Clin Oncol. 2006; 24 (21): 3347-53.
    • (2006) J Clin Oncol , vol.24 , Issue.21 , pp. 3347-3353
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3    Fuchs, C.S.4    Ramanathan, R.K.5    Williamson, S.K.6
  • 8
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz LB, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol. 2008; 26 (12): 2013-9.
    • (2008) J Clin Oncol , vol.26 , Issue.12 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Diaz-Rubio, E.3    Scheithauer, W.4    Figer, A.5    Wong, R.6
  • 9
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
    • Van Cutsem E, Kohne CH, Lang I, Folprecht G, Nowacki MP, Cascinu S, et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol. 2011; 29 (15): 2011-9.
    • (2011) J Clin Oncol , vol.29 , Issue.15 , pp. 2011-2019
    • Van Cutsem, E.1    Kohne, C.H.2    Lang, I.3    Folprecht, G.4    Nowacki, M.P.5    Cascinu, S.6
  • 11
    • 34447255724 scopus 로고    scopus 로고
    • Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
    • Seymour MT, Maughan TS, Ledermann JA, Topham C, James R, Gwyther SJ, et al. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. Lancet. 2007; 370 (9582): 143-52.
    • (2007) Lancet , vol.370 , Issue.9582 , pp. 143-152
    • Seymour, M.T.1    Maughan, T.S.2    Ledermann, J.A.3    Topham, C.4    James, R.5    Gwyther, S.J.6
  • 12
    • 34447277453 scopus 로고    scopus 로고
    • Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (Cairo): A phase III randomised controlled trial
    • Koopman M, Antonini NF, Douma J, Wals J, Honkoop AH, Erdkamp FL, et al. Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet. 2007; 370 (9582): 135-42.
    • (2007) Lancet , vol.370 , Issue.9582 , pp. 135-142
    • Koopman, M.1    Antonini, N.F.2    Douma, J.3    Wals, J.4    Honkoop, A.H.5    Erdkamp, F.L.6
  • 13
    • 33644843853 scopus 로고    scopus 로고
    • OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-A GERCOR study
    • Tournigand C, Cervantes A, Figer A, Lledo G, Flesch M, Buyse M, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer-a GERCOR study. J Clin Oncol. 2006; 24 (3): 394-400.
    • (2006) J Clin Oncol , vol.24 , Issue.3 , pp. 394-400
    • Tournigand, C.1    Cervantes, A.2    Figer, A.3    Lledo, G.4    Flesch, M.5    Buyse, M.6
  • 14
    • 73349089651 scopus 로고    scopus 로고
    • Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? the GERCOR OPTIMOX2 Study
    • Chibaudel B, Maindrault-Goebel F, Lledo G, Mineur L, Andre T, Bennamoun M, et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study. J Clin Oncol. 2009; 27 (34): 5727-33.
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. 5727-5733
    • Chibaudel, B.1    Maindrault-Goebel, F.2    Lledo, G.3    Mineur, L.4    Andre, T.5    Bennamoun, M.6
  • 15
    • 0037425721 scopus 로고    scopus 로고
    • Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: A multicentre randomised trial
    • Maughan TS, James RD, Kerr DJ, Ledermann JA, Seymour MT, Topham C, et al. Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial. Lancet. 2003; 361 (9356): 457-64.
    • (2003) Lancet , vol.361 , Issue.9356 , pp. 457-464
    • Maughan, T.S.1    James, R.D.2    Kerr, D.J.3    Ledermann, J.A.4    Seymour, M.T.5    Topham, C.6
  • 16
    • 84938746812 scopus 로고    scopus 로고
    • Continuous versus intermittent chemotherapy strategies in metastatic colorectal cancer: A systematic review and meta-analysis
    • Berry SR, Cosby R, Asmis T, Chan K, Hammad N, Krzyzanowska MK, et al. Continuous versus intermittent chemotherapy strategies in metastatic colorectal cancer: a systematic review and meta-analysis. Ann Oncol. 2015; 26 (3): 477-85.
    • (2015) Ann Oncol , vol.26 , Issue.3 , pp. 477-485
    • Berry, S.R.1    Cosby, R.2    Asmis, T.3    Chan, K.4    Hammad, N.5    Krzyzanowska, M.K.6
  • 17
    • 84911463475 scopus 로고    scopus 로고
    • Final results and subgroup analyses of the phase 3 CAIRO3 study: Maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC)
    • Koopman M, Simkens L, May AM, Mol L, van Tinteren H, Punt CJA. Final results and subgroup analyses of the phase 3 CAIRO3 study: Maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC). ASCO Meeting Abstracts. 2014; 32 (15-suppl): 3504.
    • (2014) ASCO Meeting Abstracts , vol.32 , Issue.15 , pp. 3504
    • Koopman, M.1    Simkens, L.2    May, A.M.3    Mol, L.4    Van Tinteren, H.5    Punt, C.J.A.6
  • 18
    • 85006667663 scopus 로고    scopus 로고
    • Maintenance strategy with Fluoropyrimidines (FP) plus Bevacizumab (Bev), Bev alone or no treatment, following a 24-week first-line induction with FP, Oxaliplatin (Ox) and Bev for patients with metastatic colorectal cancer: Mature data and subgroup analysis of the AIO KRK 0207 Phase III Study. Presented at the ESMO 2014 Congress
    • Hegewisch-Becker S, Graeven U, Lerchenmuller CA, Killing B, Depenbusch R, Steffens C, et al. Maintenance strategy with Fluoropyrimidines (FP) plus Bevacizumab (Bev), Bev alone or no treatment, following a 24-week first-line induction with FP, Oxaliplatin (Ox) and Bev for patients with metastatic colorectal cancer: Mature data and subgroup analysis of the AIO KRK 0207 Phase III Study. Presented at the ESMO 2014 Congress. Ann Oncol. 2014; 25. (suppl 4; abstr 4980)(suppl 4).
    • (2014) Ann Oncol , vol.25
    • Hegewisch-Becker, S.1    Graeven, U.2    Lerchenmuller, C.A.3    Killing, B.4    Depenbusch, R.5    Steffens, C.6
  • 19
    • 79955506636 scopus 로고    scopus 로고
    • Intermittent versus continuous chemotherapy in advanced colorectal cancer: A randomised GISCAD trial
    • Labianca R, Sobrero A, Isa L, Cortesi E, Barni S, Nicolella D, et al. Intermittent versus continuous chemotherapy in advanced colorectal cancer: a randomised GISCAD trial. Ann Oncol. 2011; 22 (5): 1236-42.
    • (2011) Ann Oncol , vol.22 , Issue.5 , pp. 1236-1242
    • Labianca, R.1    Sobrero, A.2    Isa, L.3    Cortesi, E.4    Barni, S.5    Nicolella, D.6
  • 20
    • 84925548115 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 2009; 62 (10): 1006-12.
    • (2009) J Clin Epidemiol , vol.62 , Issue.10 , pp. 1006-1012
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 21
    • 68549101842 scopus 로고    scopus 로고
    • The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: Explanation and elaboration
    • Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009; 339: b2700.
    • (2009) BMJ , vol.339 , pp. b2700
    • Liberati, A.1    Altman, D.G.2    Tetzlaff, J.3    Mulrow, C.4    Gotzsche, P.C.5    Ioannidis, J.P.6
  • 23
    • 34547450763 scopus 로고    scopus 로고
    • Practical methods for incorporating summary time-to-event data into meta-analysis
    • Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials. 2007; 8: 16.
    • (2007) Trials , vol.8 , pp. 16
    • Tierney, J.F.1    Stewart, L.A.2    Ghersi, D.3    Burdett, S.4    Sydes, M.R.5
  • 24
    • 79959571031 scopus 로고    scopus 로고
    • Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
    • Adams RA, Meade AM, Seymour MT, Wilson RH, Madi A, Fisher D, et al. Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet Oncol. 2011; 12 (7): 642-53.
    • (2011) Lancet Oncol , vol.12 , Issue.7 , pp. 642-653
    • Adams, R.A.1    Meade, A.M.2    Seymour, M.T.3    Wilson, R.H.4    Madi, A.5    Fisher, D.6
  • 25
    • 84938740932 scopus 로고    scopus 로고
    • Continuous versus intermittent chemotherapy in metastatic colorectal cancer
    • 2006 ASCO Annual Meeting Proceedings Part I Vol 24, No 18S (June 20 Supplement)
    • Alexopoulos C, Kotsori A. Continuous versus intermittent chemotherapy in metastatic colorectal cancer. Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings Part I Vol 24, No 18S (June 20 Supplement), 2006: 3582.
    • (2006) Journal of Clinical Oncology , pp. 3582
    • Alexopoulos, C.1    Kotsori, A.2
  • 26
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000; 92 (3): 205-16.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.3 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6
  • 27
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983; 67 (6): 361-70.
    • (1983) Acta Psychiatr Scand , vol.67 , Issue.6 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2
  • 28
    • 0027417437 scopus 로고
    • The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology
    • Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993; 85 (5): 365-76.
    • (1993) J Natl Cancer Inst , vol.85 , Issue.5 , pp. 365-376
    • Aaronson, N.K.1    Ahmedzai, S.2    Bergman, B.3    Bullinger, M.4    Cull, A.5    Duez, N.J.6
  • 29
    • 2942584859 scopus 로고    scopus 로고
    • Intermittent androgen deprivation therapy for prostate cancer
    • Rashid MH, Chaudhary UB. Intermittent androgen deprivation therapy for prostate cancer. Oncologist. 2004; 9 (3): 295-301.
    • (2004) Oncologist , vol.9 , Issue.3 , pp. 295-301
    • Rashid, M.H.1    Chaudhary, U.B.2
  • 30
    • 33845224929 scopus 로고    scopus 로고
    • Continuous versus intermittent tamoxifen versus intermittent/alternated tamoxifen and medroxyprogesterone acetate as first-line endocrine treatment in advanced breast cancer: An EORTC phase III study (10863)
    • Beex L, Rose C, Mouridsen H, Jassem J, Nooij M, Estape J, et al. Continuous versus intermittent tamoxifen versus intermittent/alternated tamoxifen and medroxyprogesterone acetate as first-line endocrine treatment in advanced breast cancer: an EORTC phase III study (10863). Eur J Cancer. 2006; 42 (18): 3178-85.
    • (2006) Eur J Cancer , vol.42 , Issue.18 , pp. 3178-3185
    • Beex, L.1    Rose, C.2    Mouridsen, H.3    Jassem, J.4    Nooij, M.5    Estape, J.6
  • 31
    • 33748446259 scopus 로고    scopus 로고
    • Lack of benefit of maintenance paclitaxel in first-line chemotherapy in metastatic breast cancer
    • Gennari A, Amadori D, De Lena M, Nanni O, Bruzzi P, Lorusso V, et al. Lack of benefit of maintenance paclitaxel in first-line chemotherapy in metastatic breast cancer. J Clin Oncol. 2006; 24 (24): 3912-8.
    • (2006) J Clin Oncol , vol.24 , Issue.24 , pp. 3912-3918
    • Gennari, A.1    Amadori, D.2    De Lena, M.3    Nanni, O.4    Bruzzi, P.5    Lorusso, V.6
  • 32
    • 70249130544 scopus 로고    scopus 로고
    • Duration of chemotherapy for advanced non-small-cell lung cancer: A systematic review and meta-analysis of randomized trials
    • Soon YY, Stockler MR, Askie LM, Boyer MJ. Duration of chemotherapy for advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomized trials. J Clin Oncol. 2009; 27 (20): 3277-83.
    • (2009) J Clin Oncol , vol.27 , Issue.20 , pp. 3277-3283
    • Soon, Y.Y.1    Stockler, M.R.2    Askie, L.M.3    Boyer, M.J.4
  • 33
    • 60149111149 scopus 로고    scopus 로고
    • Optimal duration of first-line chemotherapy for advanced non-small cell lung cancer: A systematic review with meta-analysis
    • Lima JP, dos Santos LV, Sasse EC, Sasse AD. Optimal duration of first-line chemotherapy for advanced non-small cell lung cancer: a systematic review with meta-analysis. Eur J Cancer. 2009; 45 (4): 601-7.
    • (2009) Eur J Cancer , vol.45 , Issue.4 , pp. 601-607
    • Lima, J.P.1    Dos Santos, L.V.2    Sasse, E.C.3    Sasse, A.D.4
  • 34
    • 34548242294 scopus 로고    scopus 로고
    • Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer
    • de Gramont A, Buyse M, Abrahantes JC, Burzykowski T, Quinaux E, Cervantes A, et al. Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer. J Clin Oncol. 2007; 25 (22): 3224-9.
    • (2007) J Clin Oncol , vol.25 , Issue.22 , pp. 3224-3229
    • De Gramont, A.1    Buyse, M.2    Abrahantes, J.C.3    Burzykowski, T.4    Quinaux, E.5    Cervantes, A.6
  • 35
    • 84908137867 scopus 로고    scopus 로고
    • Six versus fewer planned cycles of first-line platinum-based chemotherapy for non-small-cell lung cancer: A systematic review and meta-analysis of individual patient data
    • Rossi A, Chiodini P, Sun JM, OBrien ME, von Plessen C, Barata F, et al. Six versus fewer planned cycles of first-line platinum-based chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data. Lancet Oncol. 2014; 15 (11): 1254-62.
    • (2014) Lancet Oncol , vol.15 , Issue.11 , pp. 1254-1262
    • Rossi, A.1    Chiodini, P.2    Sun, J.M.3    OBrien, M.E.4    Von Plessen, C.5    Barata, F.6
  • 36
    • 24644457747 scopus 로고    scopus 로고
    • Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico DellItalia Meridionale
    • Colucci G, Gebbia V, Paoletti G, Giuliani F, Caruso M, Gebbia N, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico DellItalia Meridionale. J Clin Oncol. 2005; 23 (22): 4866-75.
    • (2005) J Clin Oncol , vol.23 , Issue.22 , pp. 4866-4875
    • Colucci, G.1    Gebbia, V.2    Paoletti, G.3    Giuliani, F.4    Caruso, M.5    Gebbia, N.6
  • 37
    • 77955164514 scopus 로고    scopus 로고
    • Phase III study of first-line XELOX plus bevacizumab (BEV) for 6 cycles followed by XELOX plus BEV or single-agent (s/a) BEV as maintenance therapy in patients (pts) with metastatic colorectal cancer (mCRC): The MACRO Trial (Spanish Cooperative Group for the Treatment of Digestive Tumors [TTD])
    • Tabernero J, Aranda E, Gomez A, Massuti B, Sastre J, Abad A, et al. Phase III study of first-line XELOX plus bevacizumab (BEV) for 6 cycles followed by XELOX plus BEV or single-agent (s/a) BEV as maintenance therapy in patients (pts) with metastatic colorectal cancer (mCRC): The MACRO Trial (Spanish Cooperative Group for the Treatment of Digestive Tumors [TTD]). ASCO Meeting Abstracts. 2010; 28 (15-suppl): 3501.
    • (2010) ASCO Meeting Abstracts , vol.28 , Issue.15 , pp. 3501
    • Tabernero, J.1    Aranda, E.2    Gomez, A.3    Massuti, B.4    Sastre, J.5    Abad, A.6
  • 38
    • 84871667344 scopus 로고    scopus 로고
    • Bevacizumab (Bev) with or without erlotinib as maintenance therapy, following induction first-line chemotherapy plus Bev, in patients (pts) with metastatic colorectal cancer (mCRC): Efficacy and safety results of the International GERCOR DREAM phase III trial
    • Tournigand C, Samson B, Scheithauer W, Lledo G, Viret F, Andre T, et al. Bevacizumab (Bev) with or without erlotinib as maintenance therapy, following induction first-line chemotherapy plus Bev, in patients (pts) with metastatic colorectal cancer (mCRC): Efficacy and safety results of the International GERCOR DREAM phase III trial. ASCO Meeting Abstracts. 2012; 30 (18-suppl):LB A3500.
    • (2012) ASCO Meeting Abstracts , vol.30 , Issue.18 , pp. A3500
    • Tournigand, C.1    Samson, B.2    Scheithauer, W.3    Lledo, G.4    Viret, F.5    Andre, T.6
  • 39
    • 84861432557 scopus 로고    scopus 로고
    • Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDIC-VII study
    • Tveit KM, Guren T, Glimelius B, Pfeiffer P, Sorbye H, Pyrhonen S, et al. Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: the NORDIC-VII study. J Clin Oncol. 2012; 30 (15): 1755-62.
    • (2012) J Clin Oncol , vol.30 , Issue.15 , pp. 1755-1762
    • Tveit, K.M.1    Guren, T.2    Glimelius, B.3    Pfeiffer, P.4    Sorbye, H.5    Pyrhonen, S.6
  • 40
    • 0027478423 scopus 로고
    • Meta-analysis of the literature or of individual patient data: Is there a difference?
    • Stewart LA, Parmar MK. Meta-analysis of the literature or of individual patient data: is there a difference? Lancet. 1993; 341 (8842): 418-22.
    • (1993) Lancet , vol.341 , Issue.8842 , pp. 418-422
    • Stewart, L.A.1    Parmar, M.K.2
  • 41
    • 84946208916 scopus 로고    scopus 로고
    • Selecting for maintenance or stop-and-go strategy in metastatic colorectal cancer
    • Abstracts 2013;49 (2-suppl): 2222013
    • De Gramont A. Selecting for maintenance or stop-and-go strategy in metastatic colorectal cancer. The European Cancer Congress 2013: Abstracts 2013;49 (2-suppl): 2222013.
    • (2013) The European Cancer Congress
    • De Gramont, A.1
  • 42
    • 0036302615 scopus 로고    scopus 로고
    • Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: Results of a multivariate analysis of 3825 patients
    • Kohne CH, Cunningham D, Di Costanzo F, Glimelius B, Blijham G, Aranda E, et al. Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 patients. Ann Oncol. 2002; 13 (2): 308-17.
    • (2002) Ann Oncol , vol.13 , Issue.2 , pp. 308-317
    • Kohne, C.H.1    Cunningham, D.2    Di Costanzo, F.3    Glimelius, B.4    Blijham, G.5    Aranda, E.6
  • 43
    • 79958806016 scopus 로고    scopus 로고
    • Four molecular subtypes of colorectal cancer and their precursor lesions
    • Kang GH. Four molecular subtypes of colorectal cancer and their precursor lesions. Arch Pathol Lab Med. 2011; 135 (6): 698-703.
    • (2011) Arch Pathol Lab Med , vol.135 , Issue.6 , pp. 698-703
    • Kang, G.H.1
  • 44
    • 84877619075 scopus 로고    scopus 로고
    • A colorectal cancer classification system that associates cellular phenotype and responses to therapy
    • Sadanandam A, Lyssiotis CA, Homicsko K, Collisson EA, Gibb WJ, Wullschleger S, et al. A colorectal cancer classification system that associates cellular phenotype and responses to therapy. Nat Med. 2013; 19 (5): 619-25.
    • (2013) Nat Med , vol.19 , Issue.5 , pp. 619-625
    • Sadanandam, A.1    Lyssiotis, C.A.2    Homicsko, K.3    Collisson, E.A.4    Gibb, W.J.5    Wullschleger, S.6


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